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WO/2024/112802A1 |
In some aspects, the present disclosure pertains to medical devices, at least a portion of which comprises a polymeric region comprising a poly(urethane amide) that comprises urethane (-O-CO-NH-) groups, and amide (-CO-NH-) groups. In ot...
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WO/2024/109943A1 |
Provided are an antibacterial nanomaterial, a preparation method therefor, and use thereof. The antibacterial nanomaterial comprises polydopamine nanoparticles and a silver layer loaded on the surfaces of the polydopamine nanoparticles. ...
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WO/2024/112312A1 |
The present invention relates to hydrogels containing hyaluronic acid with improved rheological properties. Within the scope of the invention, Niacinamide, which is a derivative of vitamin B3 having a basic nature, is utilized instead of...
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WO/2024/064792A3 |
The present disclosure relates to a composition for three-dimensional cell and/or organoid culture, comprising a phase-changing matrix comprising a partially ordered polypeptide, and a plurality of cells encapsulated in the matrix. In em...
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WO/2024/109777A1 |
Provided are an artificial skin stent and a printing method. The artificial skin stent comprises hydrogel layers (10) and fiber membrane layers (20). The hydrogel layers (10) include a lower hydrogel layer (11), a middle hydrogel layer (...
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WO/2024/108469A1 |
The present invention belongs to the technical field of bone tissue repair materials, and provides a shape memory material with a chelating system. The shape memory material with a chelating system comprises polyurethane and a metal comp...
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WO/2024/112747A1 |
A system for treating an eye comprising a tissue stored within a lumen of an elongated cannula, the tissue comprises scleral, amniotic membrane, or acellular biomatrix tissue and having an elongated form factor. Related devices, systems,...
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WO/2024/112551A1 |
An implant includes a substrate having an outer surface, a first layer disposed on the outer surface of the substrate, and a second layer disposed on the outer surface of the substrate. The first layer includes a polymeric material.
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WO/2024/109180A1 |
Disclosed are a method for preparing a macromolecular valve leaflet material, a macromolecular valve leaflet, and an artificial valve. The method comprises: step 1, soaking a reinforcing material in a first macromolecule solution, and dr...
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WO/2024/109011A1 |
The present invention relates to a method for preparing a high-strength interpenetrating polymer network (IPN) hydrogel blood vessel having a directionally arranged fiber microstructure. The method comprises: preparing a raw material of ...
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WO/2024/109747A1 |
Provided are a biological patch, a preparation method therefor, and use thereof. The biological patch is a fish skin-based biological patch, and comprises more than or equal to 1.4 wt% of a first fatty acid and less than or equal to 2 wt...
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WO/2024/104273A1 |
The present invention relates to a polyurethane copolymer. The soft segment of the polyurethane copolymer comprises a polydimethylsiloxane structure and a polycarbonate structure, the polydimethylsiloxane structure being shown as formula...
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WO/2024/106970A1 |
The present invention relates to a powder formulation for tissue repair and an injectable composition for tissue repair comprising same and, more particularly, to: a powder formulation comprising a copolymer of a hydrophilic biocompatibl...
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WO/2024/107917A1 |
The present disclosure relates to compositions and methods for restoring enamel, e.g., on tooth surfaces.
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WO/2024/103389A1 |
Provided are a method for preparing a biological valve material by means of double-bond polymerization after aldehyde crosslinking, as well as the biological valve material and use. The preparation method comprises: step S110, contacting...
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WO/2024/106444A1 |
The present invention provides a drug which can improve the implantation rate of an embryo and can be used in combination with an existing drug used in the treatment of infertility, a screening method by which such a drug can be reliably...
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WO/2024/103392A1 |
A method for preparing a biological valve material by copolymerization and crosslinking, a biological valve material, and use. The preparation method comprises: step S110, contacting a biological material with an aldehyde group crosslink...
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WO/2024/103510A1 |
Disclosed herein are a degradable drug-loaded coating on the surface of a zinc alloy implant, a preparation method therefor, and use thereof. Firstly, photosensitive degradable polycarbonate with a metal ion capture function is synthesiz...
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WO/2024/105208A1 |
The present invention pertains to artificial vascular prostheses for the repair of damaged or diseased blood vessels. There is currently a urgent and unmet clinical need for vascular prostheses, particularly those of small-diameters. The...
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WO/2024/103630A1 |
Provided are a composite coating on the surface of a biomedical titanium alloy and a preparation method therefor. Said coating can effectively enhance the antibacterial performance, the soft tissue affinity, and the synosteosis capacity ...
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WO/2024/106959A1 |
The present invention relates to a composition for promoting tissue regeneration, the composition comprising stem cell spheroids. The stem cell spheroids according to the present invention can be produced in a uniform size and are standa...
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WO/2024/103390A1 |
A biological valve material based on aldehyde group crosslinking, a preparation method therefor, and use thereof. The preparation method comprises: step S110, contacting a biological material with an aldehyde group crosslinking agent sol...
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WO/2024/108204A1 |
Injectable fiber-hydrogel composites are provided. The injectable fiber-hydrogels include a matrix metalloproteinase (MMP)-degradable hyaluronic acid (HA) hydrogel and a fibrous hydrogel comprising a guest macromer of a HA backbone and h...
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WO/2024/108037A1 |
Equine-specific therapeutic compositions comprising placental-derived materials and methods of use, and method of producing said equine-specific therapeutic compositions that is dear, safe, and physiologically and biologically active liq...
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WO/2024/098286A1 |
Provided in the present application is a neuromodulation device, comprising: a substrate, living cells grown on the surface of the substrate, and a hydrogel used for encapsulating the living cells on the surface of the substrate, wherein...
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WO/2024/100177A1 |
The present invention relates to an artificial ligament (10) comprising an elongate braided hollow sheath (20) having an inner volume and a deformable insert (30) accommodated in the inner volume over at least part of the length of the s...
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WO/2024/098892A1 |
The present invention provides an anti-calcification animal-derived biomedical material, a preparation method therefor, and use thereof in artificial heart valves and biological patches. For the anti-calcification animal-derived biomater...
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WO/2024/098490A1 |
Provided are a nerve conduit and a preparation method therefor. The nerve conduit comprises response units and electrically conductive units which are alternately arranged in sequence. The response units and the electrically conductive u...
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WO/2024/102476A1 |
Provided herein, inter alia, are soft tissue devices including hydrogel composites, compositions, and use for fat grafting and regenerating soft tissue.
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WO/2024/102853A1 |
Compositions and methods for delivery of therapeutic agents to an individual in need thereof, for prevention/reduction of tissue adhesion, and for 3D printing are disclosed herein. In some embodiments, the composition comprises octadecyl...
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WO/2024/101418A1 |
Disclosed is a resin composition which contains a thermoplastic polyurethane (A1) and a (meth)acrylic copolymer (B), wherein: the (meth)acrylic copolymer (B) is an amphiphilic copolymer; and the difference between the refractive index of...
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WO/2024/101906A1 |
The present invention relates to a human implant for inducing body vessel regeneration and a method of treating lymphedema or ischemic disease using same. A structure according to the present invention provides appropriate physical stren...
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WO/2024/102465A1 |
Embodiments herein relate to polyacrylic acid containing lubricious coatings for medical devices. In an embodiment, a lubricious coated medical device is included having a substrate and a first layer disposed over the substrate. The firs...
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WO/2024/098285A1 |
Provided is an exosome program-controlled tissue repair material, comprising: a flexible substrate (110), a stem cell (120) growing on the surface of the flexible substrate (110), and a hydrogel (130) configured for encapsulating the ste...
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WO/2024/096102A1 |
The present invention provides a pre-sintered body and a composition which are for obtaining a zirconia sintered body that, after short sintering in which the time of holding at a maximum sintering temperature is 10 minutes or less, main...
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WO/2024/098068A1 |
The present disclosure provides mixed-surface polyamidoamine (PAMAM) polymers comprising cationic surface groups and neutral surface groups. Also provided are scavenging apparatuses, microfibers, filters, and other devices comprising the...
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WO/2024/092856A1 |
The present invention relates to the technical field of biomedical materials, and particularly, to a super-hydrophobic self-cleaning anticoagulant composite coating material, a method for preparing same, and use thereof. In the provided ...
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WO/2024/094890A1 |
An implant for cartilage and meniscus repair and formed from decellularized cartilage extracellular matrix (dECM) ink is described. The dECM ink has a dECM concentration of 5 to 10% (w/v), preferably a pH of 10-12, and the dECM in the im...
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WO/2024/094556A1 |
The present invention discloses a method for generating a plurality of biocompatible fibroin fibres (6) generated from the turbulent mixing produced in the inner mixing region of a nebulizer, among a dope stream comprising a dope solutio...
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WO/2024/094887A1 |
The present invention relates to the production of skin substitutes with a defined ratio of blood endothelial cells (BEC), to lymphatic endothelial cells (LEC), and their use in medicine.
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WO/2024/095956A1 |
Provided is a method for modifying crystalline calcium phosphate particles into amorphous calcium phosphate by wet grinding using a bead mill, without causing particle agglomeration. A slurry that contains calcium phosphate particles and...
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WO/2023/034614A9 |
Systems and methods for nerve repair can include a polymer configured to form an elongated conduit to receive an in vivo nerve therein and provide a mechanical stabilization to the in vivo nerve. The polymer can be configured to degrade ...
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WO/2024/097403A1 |
A dissolvable stretch ring (100) including a biodegradable polymer positioned on or adjacent to at least one haptic of an intraocular lens (IOL) is described. The dissolvable stretch ring (10) can be included in an IOL arrangement, compr...
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WO/2024/097250A1 |
This disclosure provides a respirator}- tract insertable device comprising a mesh that carries a probiotic composition. For example, a method of treating or preventing chronic obstructive pulmonary disease (COPD) or a respiratory infecti...
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WO/2024/096942A1 |
A medical device that is at least partially formed of a metal alloy that includes at least 15 awt.% rhenium, and a medical device that is partially or fully formed of such metal alloy.
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WO/2024/097114A1 |
The disclosed inventions relate to an improved bioceramic coated product and methods of characterizing coated products. More specifically, the disclosed inventions relate to an improved bioceramic coated product comprising bioceramic par...
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WO/2024/096401A1 |
One aspect relates to a pharmaceutical composition for wound healing or skin tissue regeneration, the pharmaceutical composition containing an extracellular matrix and a kelp extract. According to one aspect, the extracellular matrix and...
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WO/2024/086893A1 |
Dilute zinc alloys and processes for their manufacture are provided. The alloys contain iron and/or copper as major alloying metals and are prepared using hot extrusion and optional post-extrusion annealing. The alloys exhibit high stren...
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WO/2024/089422A1 |
An apparatus (105) for manufacturing a tubular biological structure (165) comprises a tubular member (150) configured to be rotated, wherein the tubular member (150) comprises a tubular wall extending from a first end (151) and a second ...
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WO/2024/089699A1 |
Formulations usable for additive manufacturing of a three-dimensional object featuring, in at least a portion thereof, a biological and/or biocompatible material, which utilize minocycline and/or any other compound that features a tetrac...
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