| Document |
Document Title |
|
WO/2021/142884A1 |
Disclosed is the use of aspirin in the preparation of a platelet-targeted drug delivery system. Aspirin is co-incubated with a platelet in vitro to inhibit the aggregation and deformation of the platelet, so that the platelet is used as ...
|
|
WO/2021/142460A1 |
A method for treating cancer in a patient in which a sample of the tumor or cancer is obtained from the patient and screened for responsiveness to 2,2'-dithio-bis-ethane sulfonate analogs. The sample is treated with 2,2'-dithio-bis-ethan...
|
|
WO/2021/142395A1 |
Provided are therapeutic combinations or formulations of drugs comprising triple monoamine reuptake inhibitors, melanin concentrating hormone receptor 1 (MCHRl) antagonists and diazoxide or its formulations and various combinations there...
|
|
WO/2021/135482A1 |
A water-soluble conjugated polymer for photothermal therapy, a polymerized monomer thereof, a preparation method therefor, and application thereof. The water-soluble conjugated polymer has good solubility in an aqueous solution, has exce...
|
|
WO/2021/136262A1 |
A nano composite material, comprising BiOX particles having oxygen vacancy defects and a coating; the coating is a biocompatible material; when under near-infrared radiation, the photothermal conversion efficiency of the nano composite i...
|
|
WO/2021/137932A1 |
The present invention relates to the use of iodide compounds, to treat and prevent cachexia and cardiotoxicity resulting from treatment with an anti-cancer therapy.
|
|
WO/2021/127814A1 |
Disclosed are a photo-nanovaccine for cancer treatment, a preparation method therefor and an application thereof. The photo-nanovaccine comprises a black phosphorus quantum dot and an exosome, the black phosphorus quantum dot being wrapp...
|
|
WO/2021/132636A1 |
The present disclosure provides a composition, a combination product, a medical device and the like for treating or preventing cancer or a tumor or preventing the recurrence of the cancer or the tumor. The present disclosure provides a c...
|
|
WO/2021/129678A1 |
Disclosed are a conjugate with a radiation-responsive group and the use thereof. The conjugate has a general formula P—L—D, wherein P is a radiation-responsive group containing aryl or heteroaryl; L is not present or is a divalent li...
|
|
WO/2021/130237A1 |
The present invention relates to tumor-targeted probes for use as medicaments and for use in treatment of cancer and to methods of treatment wherein such probes are used. The probes consist of a light-absorbing molecule linked directly o...
|
|
WO/2021/134010A1 |
Viability of cancer cells (e.g., glioblastoma cells) can be reduced by administering mannose to the cancer cells; and applying an alternating electric field with a frequency between 100 and 500 kHz to the cancer cells. Susceptibility to ...
|
|
WO/2021/134023A2 |
Peptide-based systems containing hydrophobic amino acids (e.g., tryptophan), charged amino acids (e.g., arginine), and/or sulfur-containing amino acids (e.g., cysteine), which can be used either alone or in combination with nanoparticles...
|
|
WO/2021/125611A1 |
The present invention provides an eco-friendly smart photosensitizer comprising a conjugate of hydroxypropylmethyl cellulose and porfimer sodium photosensitizer, and a photo-stem cell therapy product comprising the photosensitizer. The p...
|
|
WO/2021/122969A1 |
The present invention relates to a method comprising the steps of provision of a sample derived from a blood sample of a subject that has received a checkpoint-inhibitor therapy and is suspected of developing or has developed symptoms of...
|
|
WO/2021/124028A1 |
The present invention relates to photoresponsive triggered-release nanoparticles and the use thereof as a new strategy for providing antitumour treatment for breast cancer with increased specificity. Described are natural killer (NK) cel...
|
|
WO/2021/125641A1 |
The present invention relates to a method for controlling the active discharge of a self-healing peptide motif, for auditory enhancement, according to biological environment and external stimuli, and, more specifically, to: a biomedical ...
|
|
WO/2021/114909A1 |
A photodynamic therapy system based on a biodegradable two-dimensional material nanosheet, comprising a two-dimensional material nanosheet, a dispersant having a modification effect on the upper and lower surfaces of the two-dimensional ...
|
|
WO/2021/114605A1 |
Disclosed is a liver-targeted therapeutic drug based on a sugar-based metal framework material and a preparation method therefor. The liver-targeted therapeutic drug is composed of A, B, C, and D, wherein A is selected from one or more o...
|
|
WO/2021/116748A2 |
|
|
WO/2021/119358A1 |
Methods for treating, selecting a treatment, and monitoring a treatment for an inflammatory bowel disease in a patient in need are disclosed. Treatments include administering an antifungal compound. The method for selecting and monitorin...
|
|
WO/2021/119555A2 |
The present disclosure provides compositions and methods for enhancing immunity (or immune response). The compositions and methods are particularly useful for potentiating immune response of a lymphoid cell. The compositions and methods ...
|
|
WO/2021/113986A1 |
Molecular complexes and compositions containing the same are disclosed herein. More specifically, carbohydrate polymers, for example hyaluronic acid or a salt thereof, are complexed with a biologically active compound selected from natur...
|
|
WO/2021/116331A1 |
The present invention concerns amphiphilic copolymers that may be photo- or redox-cleavable and that may assemble into polymersomes. It also concerns their process of preparation and their use as drug carriers.
|
|
WO/2021/114164A1 |
Provided is a method for preparing an exosome, which falls within the field of biotechnology. The method comprises the following steps: placing human astrocytes in a medium for culturing; performing circulatory stimulation on the human a...
|
|
WO/2021/119146A1 |
This invention is directed to compositions and methods for treating cornea pathologies. Specifically, aspects of the invention are drawn to a biomolecule and methods of using the same to treat cornea pathologies that affect tissue innerv...
|
|
WO/2021/112122A1 |
[Problem] The present invention addresses the problem of developing a catalyst compound which has blood-brain barrier penetration properties and enables the oxygenation of amyloids in a body upon being irradiated with light from the outs...
|
|
WO/2021/113401A2 |
Compositions, methods and kits for treating active or passive titin-induced cardiac muscle stiffness by administering an HDAC6 specific inhibitor or an HDAC6 activator.
|
|
WO/2021/112174A1 |
Provided is a novel application of near-infrared ray immunological therapy. Specifically, provided are: a target-specific complex having a structure in which a near-infrared light sensitive substance is linked to IgY specific to targets ...
|
|
WO/2021/113734A1 |
Provided are compositions, combinations, and methods and uses for treating a subject having a tumor, lesion or cancer. In some aspects, the methods and uses include administering a targeting molecule that binds PD-L1, conjugated with pht...
|
|
WO/2021/105620A1 |
The invention concerns a biocompatible oily ferrofluid comprising magnetic nanoparticles based on iron oxide and an oily phase comprising at least one fatty acid ester, characterized in that said magnetic nanoparticles are surface-functi...
|
|
WO/2021/108705A2 |
The present application relates to a method for inhibiting calcification of aortic valves or inhibiting aortic valve sclerosis/fibrosis. The method involves selecting a subject having, or at risk of developing, calcific aortic valve dise...
|
|
WO/2021/104112A1 |
Provided is a drug comprising live cyanobacteria, which improves tumor hypoxia by generating oxygen by means of photosynthesis under laser irradiation so as to change the micro-environment of a tumor and achieve an oxygen-increasing tumo...
|
|
WO/2021/104834A1 |
The present disclosure relates to combination therapies for the treatment of pathological conditions, such as cancer. In particular, the present disclosure relates to combination therapies comprising treatment with Antibody Drug Conjugat...
|
|
WO/2021/103232A1 |
A preparation method for a drug carrier and an application. The preparation method comprises preparation of ZIF-M nanoparticles, preparation of ZIF-M@PVP/DMPC nanoparticles, and preparation of ZIF-M@LIP nanoparticles. Nanoparticles are p...
|
|
WO/2021/098688A1 |
A function of a naturally existing cyanobacteria, aiming to provide a photosensitizer having a simple preparation process. It utilizes the characteristics that cyanobacteria photosynthetically produces oxygen after being irradiated, thus...
|
|
WO/2021/099575A1 |
Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of peritoneal carcinomatosis (PC) has been shown to significantly decrease overall survival in pa...
|
|
WO/2021/102057A1 |
The present application is related to cancer immunotherapy, e.g. stimulation of T cell mediated anti-tumor therapy.
|
|
WO/2021/097524A1 |
The present inventors have developed printable collagen bioinks using unmodified type I collagen with mechanical and structural properties that facilitate application to tissue in a structured form. In particular, the compositions of the...
|
|
WO/2021/102356A1 |
The invention provides methods and compositions for treatment of a subject with a glioma. The methods comprise administering a composition comprising Coenzyme Q10 to the subject by continuous intravenous infusion; and administering radia...
|
|
WO/2021/094396A1 |
The present invention relates to a composition and a kit of parts for antimicrobial photodynamic therapy and uses of the same, the composition comprising (a) hydrogen peroxide, carbamide peroxide and/or sodium hypochlorite and (b) at lea...
|
|
WO/2021/091281A1 |
The present invention relates to a technique for effective intranasal delivery to the brain. More specifically, the present invention is used for diagnosing, preventing or treating central nervous system encephalopathy, neurodegenerative...
|
|
WO/2021/091862A1 |
Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, di...
|
|
WO/2021/091107A1 |
The present invention relates to a pharmaceutical composition for enhancing radiation sensitivity containing ageloxime D as an active ingredient, and a composition for aiding anticancer treatment, wherein the ageloxime D increases the ra...
|
|
WO/2021/084166A1 |
The invention relates to a gold nanoparticle comprising as active ingredients the antioxidants anti-catalase, superoxide oxidase, glutathione, in combination with adenosine triphosphate, optionally combined with a polymer; a food, cosmet...
|
|
WO/2021/031320A9 |
A nano-particle based on DNA photothermal melting, a preparation method therefor, and an application thereof. The nano-particle comprises a polydopamine core, DNA double strands, and a gadolinium salt chelate. The DNA double strands are ...
|
|
WO/2021/086312A1 |
Next generation therapeutics for treatment of microrganisms (especially bacterium, fungus or certain virus) and cancer and for fluorescence diagnosis are provided. Association complex(es) effective as bactericides are formed in situ by l...
|
|
WO/2021/081642A1 |
The present disclosure relates to methods of ameliorating an inflamed state in a cell or tissue by subjecting an inflamed cell or tissue to a biophotonic composition, illuminating the biophotonic composition for a time sufficient for the...
|
|
WO/2021/084361A1 |
The present invention relates to exfoliated black phosphorus for use in the treatment of prostate cancer with or without irradiation by photothermal or photodynamic therapy.
|
|
WO/2021/082512A1 |
Provided herein is the use of biologically inert compounds that can be photoactiveted by blue light at a specific wavelength to remove or kill drug-resistant bacteria. The photoactivatable compounds include blebbistatin analogues such as...
|
|
WO/2021/076961A1 |
Compositions and methods of treatment for inhibiting capillary tube regression and/or lymphatic tube regression are described, as well as factors and signaling pathways that control the regression of capillary tube networks. Capillary tu...
|
