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Matches 1 - 50 out of 4,719

Document Document Title
WO/2018/013957A1
The present invention provides a nanocomplex comprising at least one agent and a nanocarrier. The agent is bound to the nanocarrier. The nanocarrier comprises at least one cationic polymer responsive to a stimulus, at least one anionic p...  
WO/2018/012778A1
The present invention relates to a conjugate for photodynamic diagnosis or treatment in which a peptide binds with a photosensitizer via an intracellularly degradable linkage, and to a composition for photodynamic diagnosis or treatment ...  
WO/2018/007801A1
The present disclosure relates to quantum dot nanoparticles useful for targeting and manipulating mitochondrial function, and to methods of targeting and manipulating mitochondrial function using such quantum dot nanoparticles.  
WO/2018/002170A1
Polymeric micelle - phthalocyanine nano-systems are useful as therapeutic, diagnostic, and theranostic (therapeutic and diagnostic) nano-systems for photodynamic therapy and/or fluorescence-based imaging. In particular, there is provided...  
WO/2017/214166A1
A method of forming metal nanoparticles includes applying a substance to an area of interest, applying cold plasma to the area of interest, and synthesizing nanoparticles from the substance using the cold plasma in the area of interest, ...  
WO/2017/205877A1
Methods and compositions for the prevention or reduction of platelet transfusion associated complications are provided. The subject methods include modifying donor whole blood or platelets prior to transfusion to prevent or reduce alloim...  
WO/2017/201615A1
The present disclosure provides biophotonic compositions comprising one or more fungal-derived chromophores optionally further comprising oxidants, polymer-based carriers and additional chromophores. Said compositions are disclosed to ha...  
WO/2017/205590A2
A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising...  
WO/2017/203260A1
The present invention pertains to an inventive release mechanism for extracellular vesicle (EV)-mediated intracellular and intramembrane delivery of therapeutic polypeptides. More specifically, the invention relates to EVs comprising pol...  
WO/2017/203359A1
The present disclosure provides biophotonic compositions comprising one or more photosynthetic organism-derived chromophores or a non-photosynthetic prokaryote-derived chromophores and methods useful in phototherapy. In particular, the b...  
WO/2017/199090A1
The present invention provides a pharmaceutical composition that includes a neutral carrier treated with energy proportional to biopotential of human brain or nervous tissue. Preferably, the neutral carrier is obtained from initial liqui...  
WO/2017/197531A1
Devices, materials, compounds, systems, and processes for Cherenkov-Activated Nuclear-Targeted Photodynamic Therapy that involves generating Cherenkov light within the tissue of a target volume and using this light to activate photosensi...  
WO/2017/196278A1
The invention is about a device for measuring and dosing the oxygen concentration of chemotherapy solutions by positioning oxygen probes in the tumor bed where the tumor is intense in the patient's body in intraperitoneal chemotherapy (I...  
WO/2017/195127A1
The present invention relates to silica hollow nanoparticles having inside their cavity a metal core consisting of inorganic nanostructures coated by a protective agent and agglomerated with a polymeric aggregating agent, useful in parti...  
WO/2017/195780A1
Provided is a method for restoring the three-dimensional structure of an abnormalized protein. A method for restoring the three-dimensional structure of an abnormalized protein to a normal structure by bringing a functional mineral water...  
WO/2017/191552A1
The present invention relates to an optical fiber and a device including the optical fiber. The optical fiber is an optical fiber (1) functionalized with at least one particle (1) of a polymeric gel comprising at least one photosensitive...  
WO/2017/192804A1
The presently disclosed subject matter provides agents, compositions, and methods for augmenting ablation of a target tissue in a subject in need thereof, for example, using agents that modulate protective and/or reparative cellular proc...  
WO/2017/191219A1
There is disclosed a composition comprising self-assembled nano-particles, the nano-particles comprising dendrimers having a phthalocyanine covalently bound to the periphery thereof. The composition is useful in the therapy and/or diagno...  
WO/2017/192579A1
Bio-photonic devices or target cells and cell cultures including bio-photonic devices and target cells are provided. Methods of preparing cell cultures including bio-photonic devices and target cells are also provided. Methods of analyzi...  
WO/2017/191572A1
The present invention refers to cells from a subpopulation of progenitors of endothelial cells loaded with gold nanoparticles sensitive to excitation with infrared radiation with consequent release of thermal energy, to a composition com...  
WO/2017/185016A1
Disclosed and methods for light-based treatment of skin disorders such as acne. Also disclosed are devices for providing said light-based treatments. These treatments can be used in conjunction with and augmented by topical formulations ...  
WO/2017/181000A1
A nanocomposite for detection and treatment of a target of interest including tumor cells or pathogens includes at least one nanostructure, each nanostructure having a core and a shell surrounding the core; a reporter assembled on the sh...  
WO/2017/180054A1
The present invention relates to an apparatus (1) for use in irradiation therapy, comprising an ionization module (2) adapted to emit ionization irradiation, and a power source (4) and a control unit (5) to provide a user interface. The ...  
WO/2017/178516A1
The present invention relates to a radiofrequency (RF) hyperthermia device comprising a radiofrequency carrier signal generator (1 ), a radiofrequency amplifier (4), an electrode (6) and a counter-electrode (7), a first impedance measuri...  
WO/2017/176380A1
Systems and methods are provided for locating anatomical features in the skin based on analysis of reflected light, and treating the located anatomical features using high-energy light. A labeling agent can be administered to optically d...  
WO/2017/175827A1
The purpose of the present invention is to provide a means with which it is possible to selectively improve the amount of a boron-containing compound accumulated in cancer cells. The present invention pertains to the use of at least one ...  
WO/2017/173478A1
The present invention relates to a device, comprising: an agent carrier comprising an agent transfer surface for delivery of an agent into a tissue, wherein the agent carrier comprises or is acoustically couplable to a piezoelectric subs...  
WO/2017/170531A1
Provided are light-emitting nanoparticles that exhibit light emission stability and light resistance, and are less biologically toxic. The light-emitting nanoparticles contain a matrix material and a light-emitting substance included in ...  
WO/2017/173440A1
Methods and systems for radiation therapy involve administering a payload / combination of biocompatible high-Z and semiconductor NPs to tissue, such as a tumor or an eye. Ionizing radiation may be directed towards the payload, and ioniz...  
WO/2017/173089A1
Described herein are systems and methods for manipulation of tumors with pulsed electric fields. The systems and methods described herein can be used for theranostic applications for oncology diagnosis and treatment, especially when comb...  
WO/2017/165667A1
The subject disclosure relates to compounds and compositions including chemotherapy agents and/or radiation therapy with bipolar trans carotenoids, and the use of such compounds for the treatment of various cancers including pancreatic a...  
WO/2017/164334A1
The purpose of the present invention is to provide a novel boron-containing compound which exhibits excellent accumulation in cancers due to the EPR effect, which does not take nanoparticle form and therefore exhibits high penetration in...  
WO/2017/164822A1
A core-shell plasmonic nanogapped nanostructured material is provided. The core-shell nanogapped nanostructured material has a core and at least one shell surrounding the core, wherein the at least one shell comprises a first layer compr...  
WO/2017/156616A1
The application relates to liposomal nanovesicles comprising porphyrin-lipid conjugates within the liposomal lipid bilayer. Said porphyrin-lipid conjugate comprise porphyrins that are modified with a -CH(R1)-O-R2 group and that chelate a...  
WO/2017/157874A1
Device (1) for stimulation of at least one cell (2), and/or for stimulation of at least one electrochemical reaction, comprising at least one semiconductor (3) that is configured to convert electromagnetic radiation (4) into a charge sep...  
WO/2017/156148A1
Combination treatment with Prussian blue nanoparticles and at least one immunotherapeutic treatment. Stable, functionalized Prussian blue nanoparticles, including those with enhanced stability under alkaline conditions, and methods of ca...  
WO/2017/156191A1
Provided herein are composite nanoparticles, methods of making composite nanoparticles and methods of using composite nanoparticles to treat or ameliorate various diseases, such as, for example, cancer.  
WO/2017/148454A1
The present invention relates to photoactivatable nanoparticles for photodynamic applications containing a photosensitizer, a (C8 to C22) fatty alcohol and a polymeric surfactant, preferably poly(ethylene oxide) monomethyl ether-block-po...  
WO/2017/149378A1
The system comprises a support to receive a nanoparticle assembly (NPA) and to be conveyed towards a localized area of an organism infected or at risk to be infected by microorganisms; said nanoparticle assembly (NPA) comprising a plural...  
WO/2017/151748A1
The invention provides oligonucleotide conjugates including a photolabile crosslinker attached to a cargo moiety, e.g., a therapeutic or diagnostic agent. The invention further provides reagents useful in the preparation of such conjugat...  
WO/2017/135048A1
A composition for photodynamic therapy for treating Helicobacter pylori infections which contains methylene blue and has a pH of 7.6-9.5, a Helicobacter pylori infection treatment method, a system for sterilizing lesions caused by a Heli...  
WO/2017/136504A1
A phosphor-containing drug activator and suspension thereof are provided. The suspension at least includes two or more phosphors capable of emitting ultraviolet and visible light upon interaction with x-rays. The two or more phosphors in...  
WO/2017/132248A1
A method of creating and sustaining an elevated level of free radicals in a volume of targeted tissue that utilizes targeted nanostructures (16) that include a metallic component (26) that acts to amplify the effects of a free radical-pr...  
WO/2017/132639A1
Compositions and methods for repairing or regenerating damaged tissue are disclosed. In particular, the invention relates to methods of anchoring biomolecules and/or cells to tissues in order to immobilize and concentrate therapeutic fac...  
WO/2017/125413A1
The present invention relates to mesoporous organosilica nanoparticles, the production method thereof and the uses of same in treatment involving photodynamic therapy or in imaging.  
WO/2017/120672A1
The present document describes methods and uses of biophotonic compositions which comprise at least one oxidant and at least one chromophore capable of activating the oxidant, in association with a pharmacologically acceptable carrier fo...  
WO/2017/121246A1
A composition comprising a functional substance prolonging the lifespan of singlet oxygen, an emulsifier, a photosensitizer and a preparation method thereof. An emulsion is produced from the action of the emulsifier on the functional sub...  
WO/2017/122906A1
The present invention relates to a Buddleja officinalis extract to be used in a photosensitizer for photodynamic therapy, and a method for preparing the Buddleja officinalis extract. According to the present invention, a photosensitizer ...  
WO/2017/120671A1
The present disclosure describes methods and uses of biophotonic compositions which comprise at least one oxidant and at least one chromophore capable of activating the oxidant, in association with a pharmacologically acceptable carrier ...  
WO/2017/123052A1
The present invention provides nanoparticles formed by self-assembly of an amphipathic compound in which at least one biocompatible hydrophilic polymer is linked to a cypate or a derivative thereof, and the uses thereof for photodynamic ...  

Matches 1 - 50 out of 4,719