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Matches 1 - 50 out of 4,770

Document Document Title
WO/2018/069536A1
The present invention provides TPCS2a, gemcitabine and optionally another cytotoxic agent, preferably cisplatin, for use in a method of treating a cholangiocarcinoma in a human patient comprising a photochemical internalization method. R...  
WO/2018/071837A1
Embodiments of the disclosure concern methods and compositions for treating cancer in an individual that includes combination therapy comprising radiofrequency therapy and immunotherapy. In specific embodiments, utilization of the radiof...  
WO/2018/065860A1
The present disclosure relates to quantum dot nanoparticles conjugated to ligands, and in particular quantum dot nanoparticles wherein each nanoparticle is conjugated to a polymenzable ligand. The present disclosure also relates to metho...  
WO/2018/064961A1
Provided herein is a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission fro...  
WO/2018/064963A1
Provided is use of a fullerene structure comprising at least one active ingredient selected from a group consisting of an oil-soluble hollow fullerene, an oil-soluble metallofullerene, a composition of the oil-soluble hollow fullerene an...  
WO/2018/061201A1
A phototherapy system according to the present invention includes a photosensitizer that selectively accumulates at a lesion in a living body, and a phototherapy device. A phototherapy device (10) includes a light irradiation part (3) th...  
WO/2018/060437A1
The present invention is generally directed to improvements in the treatment of cancer and diseases in the central nervous system. A new drug delivery system is provided, method for producing it and medical uses.  
WO/2018/053646A1
The present document describes methods of using compositions for inhibiting biofilm formation, or disrupting existing or developing biofilms in a subject, which composition comprises at least one chromophore and a pharmacologically accep...  
WO/2018/053645A1
The present document describes methods and uses of compositions which comprise at least one photoactivator or chromophore in association with a pharmacologically acceptable carrier for use in reducing pain that is associated with a medic...  
WO/2018/053641A1
The present disclosure relates to methods for reducing scarring of wounds. The methods comprising topically applying on the wound a biophotonic composition followed by illumination of the applied biophotonic composition with actinic ligh...  
WO/2018/052846A1
Systems and methods for capture, recording, and regeneration of subtle energy resonance signals are described herein. A system for capturing and recording the signals may include an antenna array disposed within an electromagnetic shield...  
WO/2018/045284A1
The present disclosure includes system, methods, and kits relating to creating a second structure with a plurality of first structures at a target site inside or adjacent to a host object. The methods include the step of generating a fie...  
WO/2018/044912A1
The invention provides compositions and kits including at least one nucleic acid or polypeptide molecule encoding for a mutant CoChop protein. Methods of the invention include administering a composition comprising a mutant CoChop to a s...  
WO/2018/038025A1
Provided is a near infrared light emitting material containing a porphyrin compound that is amorphous and is represented by general formula (I).  
WO/2018/036078A1
Disclosed is a method for preparing a solution containing ligand-bonded gold nanoclusters. The method comprises the following steps: providing an aqueous solution containing a gold precursor, a base and a ligand; performing a reduction r...  
WO/2018/029862A1
The efficacy of an antitumor aqueous solution that can be generated by plasma irradiation varies according to the plasma irradiation conditions, and more optimal plasma irradiation conditions depend on the type of tumor. Therefore, the p...  
WO/2018/031448A1
Embodiments of near- infrared light-cleavable heptamethine cyanine-based conjugates, particularly targeting agent-drug conjugates, according to Formula I and conjugate precursors are disclosed. The disclosed targeting agent-drug conjugat...  
WO/2018/026816A1
A phosphor-containing drug activator activatable from a Monte Carlo derived x-ray exposure for treatment of a diseased site. The activator includes an admixture or suspension of one or more phosphors capable of emitting ultraviolet and v...  
WO/2018/025165A1
A medicament comprising a parsley extract for use in the treatment and/or prevention of endometriosis is described. The medicament may also comprise an oleander extract.  
WO/2018/024716A1
The present invention refers to a process for preparing a salt solution comprising sodium chloride and extracts of parts of officinal plants, preferably extracts of olive tree leaves; the invention is further directed to the salt solutio...  
WO/2018/021138A1
Provided is a novel boron-containing compound. A compound represented by formula below is prepared and used. A black circle represents a B atom, and a white circle represents B-H; -R1 represents a group having 3-10 repeating sequences of...  
WO/2018/016014A1
The efficacy of an antitumor aqueous solution generatable by plasma irradiation varies according to plasma irradiation conditions, and appropriate plasma irradiation conditions depend on the type of tumor. Therefore, the present inventio...  
WO/2018/014111A1
There is provided methods, compositions and treatment regimens for treating cancer, or for inhibiting metastasis/recurrence of cancer in a patient using 1) a primary cancer treatment such as chemotherapy, and 2) within 12 to 120 hours po...  
WO/2018/015733A1
The invention provides a liquid-dispersible powder comprising nanoscale grains of matrix embedded with one or more isolated nanoparticles and a composition for the magnetic nanoparticle hyperthermia (MNH) treatment of tumours comprising ...  
WO/2018/013957A1
The present invention provides a nanocomplex comprising at least one agent and a nanocarrier. The agent is bound to the nanocarrier. The nanocarrier comprises at least one cationic polymer responsive to a stimulus, at least one anionic p...  
WO/2018/012778A1
The present invention relates to a conjugate for photodynamic diagnosis or treatment in which a peptide binds with a photosensitizer via an intracellularly degradable linkage, and to a composition for photodynamic diagnosis or treatment ...  
WO/2018/007801A1
The present disclosure relates to quantum dot nanoparticles useful for targeting and manipulating mitochondrial function, and to methods of targeting and manipulating mitochondrial function using such quantum dot nanoparticles.  
WO/2018/002170A1
Polymeric micelle - phthalocyanine nano-systems are useful as therapeutic, diagnostic, and theranostic (therapeutic and diagnostic) nano-systems for photodynamic therapy and/or fluorescence-based imaging. In particular, there is provided...  
WO/2017/214166A1
A method of forming metal nanoparticles includes applying a substance to an area of interest, applying cold plasma to the area of interest, and synthesizing nanoparticles from the substance using the cold plasma in the area of interest, ...  
WO/2017/205877A1
Methods and compositions for the prevention or reduction of platelet transfusion associated complications are provided. The subject methods include modifying donor whole blood or platelets prior to transfusion to prevent or reduce alloim...  
WO/2017/201615A1
The present disclosure provides biophotonic compositions comprising one or more fungal-derived chromophores optionally further comprising oxidants, polymer-based carriers and additional chromophores. Said compositions are disclosed to ha...  
WO/2017/205590A2
A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising...  
WO/2017/203260A1
The present invention pertains to an inventive release mechanism for extracellular vesicle (EV)-mediated intracellular and intramembrane delivery of therapeutic polypeptides. More specifically, the invention relates to EVs comprising pol...  
WO/2017/205590A3
A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising...  
WO/2017/203359A1
The present disclosure provides biophotonic compositions comprising one or more photosynthetic organism-derived chromophores or a non-photosynthetic prokaryote-derived chromophores and methods useful in phototherapy. In particular, the b...  
WO/2017/199090A1
The present invention provides a pharmaceutical composition that includes a neutral carrier treated with energy proportional to biopotential of human brain or nervous tissue. Preferably, the neutral carrier is obtained from initial liqui...  
WO/2017/197531A1
Devices, materials, compounds, systems, and processes for Cherenkov-Activated Nuclear-Targeted Photodynamic Therapy that involves generating Cherenkov light within the tissue of a target volume and using this light to activate photosensi...  
WO/2017/196278A1
The invention is about a device for measuring and dosing the oxygen concentration of chemotherapy solutions by positioning oxygen probes in the tumor bed where the tumor is intense in the patient's body in intraperitoneal chemotherapy (I...  
WO/2017/195127A1
The present invention relates to silica hollow nanoparticles having inside their cavity a metal core consisting of inorganic nanostructures coated by a protective agent and agglomerated with a polymeric aggregating agent, useful in parti...  
WO/2017/195780A1
Provided is a method for restoring the three-dimensional structure of an abnormalized protein. A method for restoring the three-dimensional structure of an abnormalized protein to a normal structure by bringing a functional mineral water...  
WO/2017/191552A1
The present invention relates to an optical fiber and a device including the optical fiber. The optical fiber is an optical fiber (1) functionalized with at least one particle (1) of a polymeric gel comprising at least one photosensitive...  
WO/2017/192804A1
The presently disclosed subject matter provides agents, compositions, and methods for augmenting ablation of a target tissue in a subject in need thereof, for example, using agents that modulate protective and/or reparative cellular proc...  
WO/2017/191219A1
There is disclosed a composition comprising self-assembled nano-particles, the nano-particles comprising dendrimers having a phthalocyanine covalently bound to the periphery thereof. The composition is useful in the therapy and/or diagno...  
WO/2017/192579A1
Bio-photonic devices or target cells and cell cultures including bio-photonic devices and target cells are provided. Methods of preparing cell cultures including bio-photonic devices and target cells are also provided. Methods of analyzi...  
WO/2017/191572A1
The present invention refers to cells from a subpopulation of progenitors of endothelial cells loaded with gold nanoparticles sensitive to excitation with infrared radiation with consequent release of thermal energy, to a composition com...  
WO/2017/185016A1
Disclosed and methods for light-based treatment of skin disorders such as acne. Also disclosed are devices for providing said light-based treatments. These treatments can be used in conjunction with and augmented by topical formulations ...  
WO/2017/181000A1
A nanocomposite for detection and treatment of a target of interest including tumor cells or pathogens includes at least one nanostructure, each nanostructure having a core and a shell surrounding the core; a reporter assembled on the sh...  
WO/2017/180054A1
The present invention relates to an apparatus (1) for use in irradiation therapy, comprising an ionization module (2) adapted to emit ionization irradiation, and a power source (4) and a control unit (5) to provide a user interface. The ...  
WO/2017/178516A1
The present invention relates to a radiofrequency (RF) hyperthermia device comprising a radiofrequency carrier signal generator (1 ), a radiofrequency amplifier (4), an electrode (6) and a counter-electrode (7), a first impedance measuri...  
WO/2017/176380A1
Systems and methods are provided for locating anatomical features in the skin based on analysis of reflected light, and treating the located anatomical features using high-energy light. A labeling agent can be administered to optically d...  

Matches 1 - 50 out of 4,770