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WO/2003/022161A1 |
A suture loop (21) is formed in a hollow braided suture (111) by feeding one end of a length of suture through a part in the braid of the suture (111) and into the inner lumen formed by the hollow braid. The braided configuration of the ...
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WO/2003/017851A1 |
A biocompatible fastener particularly well-suited for use in fundoplication procedures. In a preferred embodiment, the fastener is designed to break within the span of approximately three to six months after implantation and comprises a ...
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WO/2003/004071A1 |
The rate of degradation of polymers and polymer blends containing (poly) lactic acid can be increased and controlled by the inclusion of up to 10% (typically less than 1%) by weight of specific additives such as lauric acid or a derivati...
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WO/2003/000303A1 |
The present invention relates to compositions comprising a combination of one or more antiseptic and an antibiotic. It is based, at least in part, on the discovery that such combinations tend to deter the formation of antibiotic-resistan...
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WO/2002/094110A1 |
The invention provides ligating clips for surgical use which have antimicrobial or antibiotic properties. More particularly, the ligating clips have antimicrobial and/or antibiotic agents either in a coating or provided within the materi...
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WO/2002/087586A1 |
Disclosed is a sustained release system that includes a polymer and a prodrug having a solubility less than about 1 mg/ml dispersed in the polymer. Advantageously, the polymer is permeable to the prodrug and may be non-release rate limit...
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WO/2002/085385A2 |
The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and preferably in a nanocrystalline form, for re...
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WO/2002/085387A2 |
The invention relates to the use of one or more antimicrobial metals, most preferably silver, preferably formed with atomic disorder, and preferably in a nanocrystalline form,for the treatment of inflammatory skin conditions. The nanocry...
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WO/2002/085299A2 |
Therapeutic treatments using the direct application of selected structures of antimicrobial metals in free-standing powder form, solution form and/or suspension form in therapeutically effective amounts. The selected structures of antimi...
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WO/2002/085386A2 |
The invention relates to a method to induce apoptosis and to inhibit matrix metalloproteinases in a disease condition in a human or animal by contacting hyperplastic tissue, tumor tissue, or a cancerous lesion with one or more antimicrob...
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WO/2002/085384A2 |
The invention provides methods and kits to form water swellable gel coatings, preferably lubricious coatings, on substrates, and coated substrates thus formed. The coatings contain one or more antimicrobial metals formed with atomic diso...
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WO/2002/081793A1 |
The invention relates to a novel process for preparing a solution of silk or silk-like protein from a variety of potential sources, and spinning it to produce a reformed silk fibre for biomedical and other uses. The silk is pre-dissolved...
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WO/2002/076287A2 |
Sutures formed from one or more filaments are coated with an oil, such as for example, mineral oil or castor oil. The sutures exhibit good durability as reflected by fray resistance.
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WO/2002/076521A2 |
A suture filament is made from a polyolefin such as polypropylene which contains a fatty acid diester of polyethylene glycol, such as, for example, polyethylene glycol distearate.
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WO/2002/074191A2 |
An electrospinning device for generating a coat from a liquefied polymer, the device comprising: (a) a dispenser for dispensing the liquefied polymer; (b) a cavity having a longitudinal axis, comprising a first system of electrodes; the ...
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WO/2002/074189A2 |
An apparatus for forming a nonwoven material from a liquefied polymer, the apparatus comprising: (a) a precipitation electrode;(b) a dispenser spaced apart from the precipitation electrode, and defining a first axis therebetween, the dis...
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WO/2002/074190A2 |
An apparatus for forming a tubular structure from a liquefied polymer, theapparatus comprising: (a) a dispenser for dispensing the liquefied polymer;(b) a precipitation electrode being at a first potential relative to thedispenser, the p...
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WO/2002/058718A2 |
Methods of promoting angiogenesis by delivering angiogenic factors are disclosed. The factors can be delivered as a gradient to a localized area of tissue to direct vascular growth.
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WO2000056376A9 |
Devices formed of or including biocompatible polyhydroxylkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus...
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WO/2002/051464A2 |
The present disclosure invention relates to medical devices treated with a solution comprising one or more solvents and a combination of chlorhexidine free base and a water-soluble chlorhexidine salt in a weight/weight ratio of between a...
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WO/2002/049536A2 |
A vascular prosthesis comprising a first layer (12) having a predetermined first porosity and a second layer (14) having a predetermined second porosity, wherein the first layer (12) and the second layer (14) are each made of first and s...
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WO/2002/049535A2 |
A stent assembly comprising an expensible tubular supporting element (10) and at least one coat (14/16) of electrospun polymer fibers, each of the at least one coat (14/16) having a predetermined porosity, the at least one coat including...
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WO/2002/049678A2 |
An apparatus for manufacturing a polymer fiber shell from liquefied polymer is provided. The apparatus includes: (a) a precipitation electrode being for generating the polymer fiber shell thereupon; (b) a dispenser, being at a first pote...
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WO/2002/036054A1 |
This invention is an anti-proliferative drug placed onto or within a sterile sheet or mesh (10) that is designed to be placed between internal body tissues to prevent the formation of post-operative adhesions, which adhesions are really ...
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WO/2002/030478A2 |
The present invention provides an indicator for the in-situ detection of the presence of a substance or a microbe at a location. The indicator comprises a layer (8) which is susceptible to degradation by the substance or microbe or a fir...
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WO/2002/026271A1 |
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be c...
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WO/2002/026280A1 |
The present invention includes biocompatible coatings and films for use on implantable medical devices and medical devices containing such coatings and films applied to a surface thereof, which coatings/films are present on the device in...
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WO/2002/026139A1 |
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be c...
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WO/2002/026281A1 |
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be c...
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WO/2002/013701A1 |
Sutures fabricated from and/or coated with compositions including water-soluble glass are described herein. Pedgets containing water-soluble glass within the interstices of the pledget and/or coated wiht compositions including water-solu...
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WO/2002/009785A1 |
A method of treating living tissue includes applying to living tissue a biocompatible adhesive composition, where the adhesive composition contains at least one alkyl ester cyanoacrylate monomer and a polymerization initiator or accelera...
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WO/2002/004606A1 |
Compositions comprising bioactive glass compositions or extracts thereof which include ions in an appropriate concentration and ratio that they enhance osteoblast production, and methods of preparation and use thereof, are disclosed. The...
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WO/2002/002245A2 |
Electrostatic Impregnation Of Powders On SubstratesThe use of electrostatic impregnation to load materials such as binders and flavors onto substrates such as fibers and medical devices is disclosed. Substrates loaded with materials such...
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WO/2001/098364A2 |
Peptides, compositions and methods for inhibiting and controlling the growth of Burkholderia cepacia are disclosed. The composition comprises a peptide mixture with antimicrobial activity against Burkholderia cepacia and at least one car...
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WO/2001/095875A1 |
Carboxymethylcellulose compositions having a molecular weight of less than about 100 kdaltons are provided for preparing medical implants, devices and implantable pharmaceutical preparations. The medical implants, devices and implantable...
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WO/2001/091803A2 |
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The ...
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WO/2001/085214A1 |
The present invention provides a radio-opaque composition including a polymer or monomer, wherein the polymer or monomer has a non-leachable radio-opaque moiety. The non-leachable radio-opaque moiety is covalently attached to the polymer...
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WO2000051566A9 |
A method of reducing scar formation at a wound site includes contacting the wound site with an effective scar reducing amount of a cross-linked polysaccharide having a positive charge and thereby reducing scar formation as the wound site...
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WO/2001/080920A2 |
The invention provides bioabsorbable materials with antimicrobial coatings or powders which provide an effective and sustainable antimicrobial effect. Specifically, this invention provides bioabsorbable materials comprising a bioabsorbab...
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WO/2001/068722A1 |
Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers.
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WO/2001/067987A1 |
Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely of polylactide resorbable polymers, which are eng...
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WO/2001/068721A1 |
Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and hydrolyzed copolymers of vinyl acetate, ...
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WO/2001/067961A1 |
A dispenser in which a dry powder (one component of a two-part adhesive tissue sealant and/or adhesive) is stored in a container (e.g., a carpule) having a septum at one end, an open end opposite the septum, and a movable plug. The powde...
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WO/2001/060793A2 |
The invention relates to special-purpose fibers and can be used for manufacturing protective fabrics applied as adsorbent and medical suture material. Preliminary oriented fiber is exposed to a partial or total dehydrohalogenation by a t...
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WO/2001/058503A1 |
The invention relates to implantable bioprostheses (e.g. implantable biological tissues) and to compositions and methods for stabilizing them. Implantable bioprostheses stabilized as described herein exhibit improved mechanical propertie...
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WO/2001/056646A1 |
There is provided a medical device adapted for insertion into a human or animal body, characterised in that its exterior surface is coated with i) an inner first layer of a biocompatible carrier providing sustained release of a biologica...
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WO/2001/056626A1 |
Disclosed are surgical sutures, films, adhesives, and sealants made from spider silk, along or in combination with non-spider silk structural elements. Such surgical sutures, films, adhesives, and sealants are made in recombinant systems...
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WO/2001/057528A1 |
The invention relates to a method of treating a surface of an object with a hydrophobin-containing solution for providing the surface with a hydrophobin coating, the object being chosen from the group consisting of a window, a contact le...
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WO/2001/056475A1 |
There are described devices implantable in the human or animal body. Such a device takes the form of a pre-formed three-dimensional article, comprising at least in part a material which is hydratable and capable of bonding to tissue whil...
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WO/2001/043788A2 |
The present invention relates to antimicrobial compositions, methods for the production of these compositions, and use of these compositions with medical devices, such as catheters, and implants. The compositions of the present invention...
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