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WO/2001/055220A1 |
A condensation product of chitosan is formed by its reaction with a bisulfite addition compound HOCRR'SO¿3?A wherein: each of R and R' independently represents a hydrogen atom, or R represents a hydrogen atom and R' represents an option...
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WO/2001/050872A2 |
A method for produce sanitation using bacteriophages is disclosed. According to one embodiment of the present invention, the method includes the steps of (1) providing at least one bacteriophage; and (2) applying the bacteriophage to the...
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WO/2001/050866A2 |
Methods and devices for sanitation using bacteriophage are disclosed. According to one embodiment of the present invention, a method for sanitation using at least one bacteriophage includes the steps of (1) storing the at least one bacte...
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WO/2001/051027A2 |
The present invention provides bioerodable constructs for controlled release of bioactive materials. In a preferred mode, the constructs may be utilized adjacent to a biological surface. The constructs are based on a blend of two or more...
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WO/2001/051066A2 |
The present invention provides a method for reducing the risk of bacterial infection or sepsis in a susceptible patient by treating the susceptible patient with a pharmaceutical composition containing bacteriophage of one or more strains...
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WO/2001/049258A2 |
The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable po...
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WO/2001/049250A2 |
Active acne and acneiform scars are treated by topical application of a composition containing lipoic acid and/or a lipoic acid derivative such as dihydrolipoic acid, a lipoic or dihydrolipoic acid ester, a lipoic or dihydrolipoic acid a...
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WO/2001/045762A2 |
The invention is related to a medical pharmaceutical product for topical use with a medically acceptable hydrophobic polymer that - once applied on a wound - cooperates with the wound and reacts with the produced wound exudate in such a ...
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WO/2001/045760A1 |
The bone generating product comprises a coagulated matrix of platelet rich plasma with a recombinant compound for generating thrombin in presence of at least a phospholipid, and an effective amount of calcium containing compound disperse...
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WO/2001/044307A2 |
Biodegradable biocompatible hydrogels based on poly(vinyl alcohol) and methods for their preparation. The methods for preparation of the hydrogels involve the use of prepolymers. The prepolymers have a PVA backbone and pendant chains tha...
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WO/2001/037890A1 |
Propellant-free spray-on skin patch composition comprising at least one substantially water insoluble film forming agent, at least one film plasticiser agent, at least one water soluble compound, at least one organic solvent and optional...
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WO/2001/037847A2 |
A composition containing vernix to provide therapeutic treatment in a human, and a method for using the composition, are disclosed. The composition may contain a natural or synthetic medicament, or may be manipulated to regulate transpor...
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WO/2001/026624A1 |
The present invention provides a denatured albumin lamina, method of its manufacture and a method for its use in repairing lesions on solid visceral organs. The lamina can be impregnated with a variety of bioagents.
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WO/2001/026606A2 |
Scar tissue is reduced or inhibited by application of a composition containing lipoic acid and/or a lipoic acid derivative such as dihydrolipoic acid, a lipoic or dihydrolipoic acid ester, a lipoic or dihydrolipoic acid amide, a lipoic o...
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WO/2001/023011A1 |
A method of topical scar treatment or prophylaxis using a medical applicator and/or packaging device for the topical application of a fluid gel topical scar therapy agent characterised in that the agent comprises a composition comprising...
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WO/2001/019325A1 |
A topical composition with silicone oil emulsified in water. The topical composition may be made by diluting a concentrated silicone oil-in-water emulsion with water. The silicone oil of the topical composition and of the concentrated si...
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WO/2001/015734A2 |
The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a controlled fashion, and for use as medical or surg...
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WO/2001/013967A1 |
A concentrated solution of a wound healing promoter, in particular fibronectin, is used to develop solid wound dressings. The solid wound dressings containing fibronectin are easy to apply, easy to remove, and deliver fibronectin in a ra...
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WO/2001/013968A1 |
Compositions are disclosed which are normally pressure sensitive adhesive at ambient temperature, which are also absorbent of fluids, especially body fluids, and which contain 0.1 to 65 wt.% of a cyclodextrin material. Such compositions ...
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WO/2001/005443A1 |
The invention concerns a fluid adhesive protein foam, which is biocompatible, biologically absorbable and non-toxic, for surgical and/or therapeutic use, in particular for protecting/healing tissue wounds and for binding together biologi...
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WO/2001/000246A2 |
The invention provides a polymeric structure comprising a multifunctional poly(alkylene oxide), such as a poly(ethylene glycol) derivative, covalently cross-linked to a polymer selected from the group consisting of chitosan and conjugate...
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WO/2000/078259A1 |
The present invention describes the incorporation of liposomal gene constructs directly into a wound to further improve wound repair, or into wound coverage and/or closure materials to enhance the functionality of the material. The prese...
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WO/2000/076533A1 |
Dried hemoactive materials comprise both a cross-linked biologically compatible polymer and a non-cross-linked biologically compatible polymer. The cross-linked polymer is selected to form a hydrogel when exposed to blood. The non-cross-...
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WO/2000/074738A1 |
In one embodiment, the present invention relates to a method of treating a wound, involving applying to the wound a room temperature vulcanizing silicone composition comprising a crosslinkable polymer, a crosslinking agent, and a catalys...
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WO/2000/072852A1 |
A method and a composition for preventing or reducing the incidence of post surgical adhesion formation is disclosed. The method involves application of fibrin monomer composition under polymerizing conditions to the surgical wound site....
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WO/2000/062828A1 |
In general, the present invention relates to a two-phase method for forming an autologous bioadhesive sealant composition or fibrin glue wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom t...
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WO/2000/062827A2 |
This invention relates generally to two-part polymer compositions that rapidly form covalent linkages when mixed together. Such compositions are particularly well suited for use in a variety of tissue related applications when rapid adhe...
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WO/2000/050570A2 |
This invention relates to compositions and methods for modifying growth or differentiation of growth-factor dependent cells, using fusion proteins composed of a growth factor and a binding domain derived from a polysaccharidase linked di...
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WO/2000/050095A1 |
A bioadhesive wound-healing composition includes pullulan, pyruvate, an antioxidant, and a mixture of saturated and unsaturated fatty acids. The composition can be provided in the form of a film that does not self-adhere. The composition...
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WO/2000/049084A1 |
A hyaluronic acid gel composition characterized by comprising hyaluronic acid and a polymer, having undergone substantially no modification with a chemical crosslinking agent or chemical modifying agent, and having a percentage dissoluti...
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WO/2000/047621A1 |
A method for producing protein compositions comprising fibrinogen and fibronectin is disclosed, wherein a fibrinogen and fibronectin-containing starting solution is treated with a precipitating composition which comprises two different c...
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WO/2000/046319A1 |
A bioadhesive composition formed by polymerising a homogeneous aqueous reaction mixture comprising from about 5 % to about 50 %, by weight of the reaction mixture, of at least one ionic water soluble monomer, from about 10 % to about 50 ...
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WO/2000/045864A1 |
A bioadhesive composition for use as a skin adhesive, the composition formed by polymerising with cross-linking and/or entanglement an aqueous reaction mixture comprising effective amounts of at least one monomer dissolved or suspended t...
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WO/2000/044401A1 |
A melanoma inhibiting activity factor (MIA), preferably in combination with an osteoinductive protein, is a useful pharmaceutical agent for promoting bone healing and/or cartilage repair.
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WO2000009018A9 |
Polymerized type I and/or III collagen based compositions for medical use as vascular sealants and wound dressings, and the preparation thereof, are described. Prior to polymerization, the collagen monomers are prepared recombinantly whe...
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WO/2000/044287A1 |
A composition comprising of a monomer component comprised of an alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl este...
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WO/2000/044808A1 |
The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.
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WO/2000/043050A1 |
Approaches have been developed to apply multicomponent medical adhesives that improve binding of the medical adhesive (106) to a substrate (104) having covalently bound adhesive components. Use of the multicomponent adhesive reduces the ...
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WO/2000/037037A2 |
The present invention is directed to a composition for treating burns. The composition comprises a therapeutically effective amount of one or more weak organic acid compatible with huamn skin, in a suitable carrier delivered at pH 4.0 - ...
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WO/2000/035276A1 |
Disclosed are cyanoacrylate compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. These compositions provide for $i(in situ) formation of an antimicrobial polymer...
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WO/2000/033764A1 |
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic groups capable of...
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WO/2000/027327A1 |
Provided herein is a novel hemostatic polymer composition comprising a substance containing uncharged organic hydroxyl groups and a substance containing at least one of a halogen atom and an epoxy group, which is characterized as inducin...
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WO/2000/023022A1 |
Methods and compositions for forming protective and/or medicated films on body tissue. Liquid compositions contain a hydrophobically modified polymer, other than an esterified lower-hydroxyalkyl-subsituted cellulose, suspended or dissolv...
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WO/2000/010618A1 |
A sheet comprises a biodegradable, non-thrombogenic, tissue-compatible material suitable for therapeutic use by topical administration, the sheet being flexible, hydratable and activatable so that it bonds to tissue, and retains its inte...
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WO/2000/010540A1 |
The present invention provides novel 'patch in a bottle' technology in which a fluid composition, e.g., an aerosol spray, is applied onto a surface as a fluid, but then dries to form a covering element, such as a patch, having a tack fre...
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WO/2000/009176A1 |
A wound treatment composition is provided comprising an adsorbent material for adsorbing moisture on or around a wound; and, a saccharide or polysaccharide or derivative thereof. The composition is preferably carried within an envelope i...
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WO/2000/007638A1 |
Water unstable bioadhesive compositions comprising an aqueous plasticiser, a cross-linking agent, a copolymer of a hydrophilic unsaturated water soluble first monomer and a hydrophilic unsaturated water-soluble second monomer, characteri...
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WO/2000/006215A1 |
Bioadhesive compositions which comprise a hydrophobic polymer wherein the concentration of the polymer at the surface of the adhesive is greater than its concentration in the bulk of the adhesive are described; and biomedical electrodes,...
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WO/2000/006214A1 |
Bioadhesive composition comprising an aqueous plasticiser, a cross-linking agent, a copolymer of a hydrophilic unsaturated water soluble first monomer and a hydrophilic unsaturated water-soluble second monomer, characterised in that they...
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WO/2000/000180A1 |
The present invention relates to an injectable medicament for local application in the treatment of bone fractures, wherein the fractured parts are mechanically stabilized by means of an osteosynthetic implant or an external fixing eleme...
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