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Matches 551 - 600 out of 36,006

Document Document Title
WO/2016/207355A1
The invention provides a three dimensional (3D), porous, biodegradable and biocompatible tissue engineering scaffold, wherein at least 25% w/w of the scaffold is particulate egg shell membrane (ESM) distributed substantially uniformly th...  
WO/2016/202100A1
Disclosed is a polyether ether ketone/nano-hydroxyapatite dental implant consisting of a neck (1) and a root (2), the neck (1) of which is grafted with a fibronectin or a basic fibroblast growth factor, and the surface of the root (2) of...  
WO/2016/205462A1
A vascular graft, comprising a biodegradable scaffold comprising: a biodegradable polyester electrospun tubular core; a biodegradable polyester outer sheath surrounding the biodegradable polyester tubular core; and a biodegradable poly(l...  
WO/2016/203071A1
The invention relates to bioactive hydrogels produced with natural-origin ingredients, which are cross-linked via electrostatic-type interactions and which include bone morphogenetic proteins (BMP), and to the method for producing said h...  
WO/2016/203409A1
A method of forming a substrate includes mapping a three dimensional spatial distribution of at least one structural protein fiber of extracellular matrix of biological material of interest, designing a fiber assembly pattern based on an...  
WO/2016/202980A1
This invention concerns a method for sealing dentinal tubules exposed at the tooth surface as a consequence of enamel defects, based on amorphous calcium polyphosphate microparticles that, in contrast to polyphosphate-calcium salts/compl...  
WO/2016/204217A1
Provided is a novel biocompatible material having improved biocompatibility. A biocompatible material comprising a fluoropolymer, said biocompatible material being characterized in that the fluoropolymer is a copolymer of a fluoroolefin ...  
WO/2016/205468A1
Compositions for forming a silicone elastomer and the silicone elastomers thereby which have improved characteristics and which can be used for medical devices are disclosed. The composition for forming a silicone elastomer can include (...  
WO/2016/204266A1
The purpose of the present invention is to provide a polymer film which can conform to movements of the living body or to fine ruggedness and further has excellent adhesion to biotissues. The present invention provides a polymer film whi...  
WO/2016/204403A1
The present invention provides: a collagen-based sustained-release BMP delivery carrier wherein a collagen-based BMP delivery carrier has incorporated therein a bisphosphonate, and heparin is selectively secured thereto so as to increase...  
WO/2016/201577A1
Provided herein are synthetic living tissue structures comprising multiple layers of fibers deposited in solidified form from a 3D bioprinter, together with kits and methods of use related thereto. The fibers comprise a plurality of mamm...  
WO/2016/198238A1
The present invention concerns a material comprising a polymer capable of forming a hydrogel and nanoparticles comprising a solubilising lipid comprising at least one fatty acid glyceride, an amphiphilic lipid, and a co-surfactant compri...  
WO/2016/201185A1
Biomaterials, implants made therefrom, methods of making the biomaterial and implants, methods of promoting bone or wound healing in a mammal by administering the biomaterial or implant to the mammal, and kits that include such biomateri...  
WO/2016/201382A1
Provided herein are novel hyaluronic acid-based materials for in-situ gelation in wounds and other contexts, which materials are biocompatible and which have favorable gelation kinetics. The resulting hydrogels have desirable rheological...  
WO/2016/198215A1
An osteoinductive orthopedic prosthesis, comprising a metallic body, the external surface of said metallic body comprising a coating of lyophilized collagen.  
WO/2016/201202A1
Medical devices, systems, and methods for treating conditions using antithrombin-heparin conjugates are disclosed. For example, medical devices can be coated with antithrombin-heparin (ATH) resulting in reduced thrombogenicity. Various c...  
WO/2016/200288A1
A method for producing coatings on elements of human major joint endoprostheses made of titanium and titanium alloy relates to manufacturing technologies for medical products with enhanced biological compatibility and can be used on the ...  
WO/2016/200956A1
The present invention provides silicon-based polycarbonates, processes for their preparation and their use in the synthesis of copolymers, in particular segmented copolymers such as polyurethanes for biomedical applications.  
WO/2016/197491A1
Provided is a three dimensional tissue scaffold comprising a stem cell attracting element associated with a matrix, and fusion protein of stem cell attracting factor and collagen-binding domain, and methods of uses thereof.  
WO/2016/194011A1
A method is described for preparing cellularized constructs through quick prototyping comprising the following steps: (A) preparing a polymeric solution comprising one or more natural and/or synthetic polymers in a culture medium at a te...  
WO/2016/192760A1
A process of preparing a cross-linked polysaccharide product comprising hyaluronic acid and dextran, the process comprising the steps of: (a) providing a hyaluronic acid and a dextran; (b) binding the dextran to the hyaluronic acid by et...  
WO/2016/196371A1
The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.  
WO/2016/193991A1
The invention attempts to disclose few examples, few embodiments along with few illustrations for the purpose of understanding the concept of developing a novel scaffold derived from a specific breed of fish scales as a novel material po...  
WO/2016/192733A1
The present invention relates to a conduit comprising a first material, having 1) a through-going hole, 2) fibers aligned along the long-axis in the through-going hole, each fiber having a diameter in the range 200-2000 nm. The conduit i...  
WO/2016/195181A1
The present invention relates to a scaffold preparing method and a scaffold prepared thereby and, more specifically, to a scaffold preparing method for promoting bone regeneration by physically and chemically containing collagen and SDF-...  
WO/2016/196365A1
The present disclosure relates to the field of pharmaceutical compositions, ocular implants, and systems and methods for treating an ocular condition. In certain aspects, the disclosure provides ocular implant systems for treating post-o...  
WO/2016/193741A1
The present invention provides an orthopaedic material comprising a biocompatible material and at least one compound corresponding to the general formula A- [P(O)(OH)2]n wherein A means A1, A2 or A3, and wherein A1 is a linear, branched ...  
WO/2016/195462A1
The present invention relates to a functional cell sheet using an electrically activated conductive polymer, and a method of producing same and, more particularly, provides: a functional cell sheet using an electrically activated conduct...  
WO/2016/194895A1
The purpose of the present invention is to provide a sheet derived from a biological tissue, which can be used for the production of a tubular structure that can be used in an artificial blood vessel and has excellent pressure resistance...  
WO/2016/192702A2
The invention relates to molded bodies, in particular implants, comprising piezo-active calcium titanium oxide, including piezo-active doped calcium titanium oxide, the use of such calcium titanium oxide and a method for the production a...  
WO/2016/197038A1
Compositions and methods using an engineered cardiac fibroblast-derived 3 -dimensional extracellular matrix (ECM) are disclosed. The ECM includes the structural proteins fibronectin, collagen type I, collagen type III, and elastin, and f...  
WO/2016/196308A1
The invention relates to methods for generating viral-free cells using nucleases for use in transplantation. The nucleases may be CRISPR/Cas9 complexes with guided RNA to target and inactivate viral genomes within cells. The nucleases de...  
WO/2016/192702A3
The invention relates to molded bodies, in particular implants, comprising piezo-active calcium titanium oxide, including piezo-active doped calcium titanium oxide, the use of such calcium titanium oxide and a method for the production a...  
WO/2016/195152A1
The present invention relates to a method for manufacturing a collagen film using ultraviolet light, the method comprising: a collagen solution preparing step for dissolving collagen in an acidic solution to prepare a collagen solution; ...  
WO/2016/187698A1
Provided herein are compositions comprising: (a) a polymeric catechol binder, such as: polymeric dopamine, polymeric norepinephrine, polymeric epinephrine; polymeric pyrogallol, polymeric tannic acid, polymeric hydroxyhydroquinone, polym...  
WO/2016/189556A8
The present invention refers to a pharmaceutical composition comprising polysiloxane oligomers of formula (I), functionalized with at least one antimicrobial agent. Of note, the composition is stable over the time, and is able to bind th...  
WO/2016/191327A1
A wicking component is integrated into an arthroscopically deployable bone anchor, and is intended to improve soft tissue-to-bone repair. Once deployed, the fibrous wick component extends from within the bone tunnel, out of the hole, and...  
WO/2016/189097A1
The present invention relates to a process for the preparation of a topography for improved blood coagulation and/or cell attachment on a body made of titanium or a titanium alloy. The process comprises the subsequent steps of a) etching...  
WO/2016/189556A1
The present invention refers to a pharmaceutical composition comprising polysiloxane oligomers of formula (I), functionalized with at least one antimicrobial agent. Of note, the composition is stable over the time, and is able to bind th...  
WO/2016/191073A1
This document relates to decellularized nerve allografts. For example, decellularized nerve allografts and methods and materials for using decellularized nerve allografts to repair nerve injuries or bridge a severed nerve are provided.  
WO/2016/191689A1
Described are sheet-form cell growth scaffold particles, and methods for preparing and using them. The particles can be prepared using punch or other cutting operations to provide relatively uniform, populations of particles in terms of ...  
WO/2016/189474A1
The present invention relates to a scaffold for the growth and/or differentiation of neuronal precursors mainly constituted by protein nanotubes as well as to an in vitro method for the growth and/or differentiation of neuronal precursor...  
WO/2016/189094A1
The invention provides materials presenting a biologically active matrix comprising a physiological fibrillar fibronectin network, such as implantable constructs, and their use for modulating cell behaviour and fate, including cell growt...  
WO/2016/189099A1
The present invention relates to a process for the preparation of a topography for improved protein adherence on a body made of titanium or a titanium alloy. The process comprises the subsequent steps of a) pre-treating the surface compr...  
WO/2016/188342A1
Disclosed are an implantable medical instrument, a preparation method thereof and an implantable medical instrument preform for the preparation of the implantable medical instrument. The implantable medical instrument comprises a metal b...  
WO/2016/188123A1
A composition for repairing chondral defects is provided. The composition comprises a bone marrow concentrate, a cartilage fragment or powder, and a synovial membrane. Also provided is a method for treating a chondral defect in a subject...  
WO/2016/190202A1
Provided is a multi-ply tubular woven fabric structure that is useful as a base material of a hose for protecting a linear object such as a wire or cable for transporting a fluid or powder or a conduit tube, a tubular filter, an artifici...  
WO/2016/185186A1
Metal objects are treated by anodising the metal object in contact with an aqueous electrolyte, and then subjecting the anodised metal object to a reversed voltage. The anodising is performed in two stages, firstly to passivate with the ...  
WO/2016/187327A1
Biocompatible copolymers and thermo-responsive hydrogels formed from the copolymers are disclosed. The biocompatible copolymers include monomers comprising polysaccharides or derivatives thereof, therapeutic agents or derivatives thereof...  
WO/2016/184432A1
Disclosed is a tyramine derivative compound, as shown in formula (I). Also disclosed are a pharmaceutical composition comprising the compound and an application of the pharmaceutical composition in preparing a drug for treating and/or pr...  

Matches 551 - 600 out of 36,006