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Matches 551 - 600 out of 17,196

Document Document Title
WO/2013/096574
An embodiment in accordance with the present invention provides a device and method to deliver direct ionic current safely to target neural tissue, while also eliminating interruptions in the output of the device that can result from the...  
WO/2013/096176
The present invention is directed to a hemostatic material comprising a scaffold and a galvanic particulate. The galvanic particulate comprises particles made of at least two dissimilar metals. The scaffold is preferably a biocompatible ...  
WO/2013/096650
The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise par...  
WO/2013/091085
A methodology integrating multiscale analysis and design optimization to design a novel bone replacement implant made of a functionally graded cellular material that meets fatigue requirements imposed by cyclic loadings. The pore microar...  
WO/2013/096605
The invention provides biodegradable compositions and methods for using such biodegradable compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, t...  
WO/2013/091662
The present invention relates to a process for modifying the surface morphology of a medical device. The modified surface has, among other advantageous properties, an improved capacity for sorption or conjugation of a variety of bioactiv...  
WO/2013/096763
Unitary surgical devices are disclosed. Such devices may include an elongated body extending between a proximal end and a distal end, and having one or more lumens extending through the elongated body and a tip disposed at the distal end...  
WO/2013/096965
Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. The devices are adapted to permit fluid flow across the membrane in which the device ...  
WO/2013/093868
A treated surface of a device (10) for implantation or for application as a wound dressing, comprises an array of plasma-activated hydrophilic cell-adhesive areas (18) having the ability to reduce fibrous reaction, is in the form of an a...  
WO/2013/096831
Porous calcium phosphate granules and methods of making the same are provided. Embodiments of the methods include producing a solid spherical granule precursor that includes: (i) a calcium phosphate component; and (ii) a porogen componen...  
WO/2013/096650
The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise par...  
WO/2013/092857
A method of processing a surface of a metallic implant, such as a dental implant, to provide a desirable surface roughness, comprising subjecting the metallic implant to blasting with particles of one or more titanium oxides, including a...  
WO/2013/093052
A method for assembling, by brazing, a substrate comprising at least one outer surface made from pyrocarbon with parts such as balls, each comprising at least one outer surface made from pyrocarbon. An assembly obtained in this way.  
WO/2013/092339
The present invention refers to biocompatible porous scaffolds, especially bone regeneration scaffolds, comprising carbon-based nanoparticles, especially diamond nanoparticles, methods for the production of such biocompatible porous scaf...  
WO/2013/095138
The invention is directed to a biodegradable porous polymer network, to a process for preparing a biodegradable porous polymer network, and to the use of a biodegradable polymer network. More in particular, the biodegradable porous polym...  
WO/2013/091865
The tissue construct with viable cells in an extracellular matrix made of fibrin is produced with a special method, in which a matrix material and cells are shaped into a hollow body, in particular a tubular hollow body, by means of a ro...  
WO/2013/096249
The present disclosure provides a tissue product comprising a tissue sheet, The sheet can be formed from a plurality of tissue matrix fragments.  
WO/2013/093921
An isolated fiber is disclosed comprising: i. an internal core which comprises a synthetic polymer; ii. an outer layer which comprises collagen; and iii. an intermediate layer disposed between the internal core and the outer layer which ...  
WO/2013/096340
The present invention relates to a biologically active medical device, which includes a matrix seeded with progenitor cells, and then covered by ciliated tissue. The matrix is capable of enabling cellular migration. The ciliated tissue i...  
WO/2013/091050
The present invention describes a method for producing biomaterials by using an infra-red laser to cause two polymer materials to adhere to each other. These biomaterials have numerous uses, in particular as polymer supports, scaffolds a...  
WO/2013/096252
The present disclosure provides tissue fillers. The tissue fillers can include a plurality of tissue particles formed from acellular tissue matrix fragments. The tissue fillers can be used to fill tissue sites, such as voids formed after...  
WO/2013/087073
The invention relates to an implant with a structured surface and to methods for producing the implant with a structured surface, and to methods for determining the wetting properties of said implant.  
WO/2013/087073
The invention relates to an implant with a structured surface and to methods for producing the implant with a structured surface, and to methods for determining the wetting properties of said implant.  
WO/2013/088347
The invention relates to a mineralised composite material and methods of forming such a material. The process comprises mineralisation of a chitin template with calcium carbonate. The mineralised composite material of the invention has s...  
WO/2013/089078
The purpose of the present invention is to provide a resin composite that is more wear resistant and has higher fracture energy than conventional resin composites. A resin composite that: is manufactured using 40 to 400 weight parts of i...  
WO/2013/085562
A medical device having a lubricious coating on at least a section of the medical device, and a method of coating a medical device, the lubricious coating being applied over a primer coating which is directed applied to the medical devic...  
WO/2013/084817
The present invention provides a membrane for inducing the regeneration of a bone/tissue, which comprises: an organic base; and a new bone induction layer which is arranged on one surface or both surfaces of the organic base and comprise...  
WO/2013/086236
This disclosure generally relates to cell-based therapies for treatment of visual disorders, including disorders of the cornea. Methods are exemplified for directed differentiation of corneal cells from stem cells. Compositions of cornea...  
WO/2013/086024
The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.  
WO/2013/084204
The invention relates to a hydrophobic thermoplastic copolymer which is in particular of use for manufacturing and/or coating medical devices, in particular implantable medical devices, characterized in that it is obtained by copolymeriz...  
WO/2013/086236
This disclosure generally relates to cell-based therapies for treatment of visual disorders, including disorders of the cornea. Methods are exemplified for directed differentiation of corneal cells from stem cells. Compositions of cornea...  
WO/2013/084137
A spinal cord device comprises a body formed of a biocompatible, biodegradable matrix. The body includes proximal, cranial and distal, caudal surfaces for connection to two ends of an injured spinal cord after removal of an injured secti...  
WO/2013/083511
The invention relates to a thermoplastic polyurethane urea that can be obtained by reacting the following components: component A), a polycarbonate polyol A1) which comprises at least one structural unit of general formula (I) and, if de...  
WO/2013/086283
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to TMJ implantation materials and implants (e.g., temporomandi bular join...  
WO/2013/083935
The invention relates to a process for preparing cements used for reparative or reconstructive bone surgery, in particular for fixing prostheses, for bone repair and for vertebroplasty, and obtained from liquid single-phase formulations....  
WO/2013/083844
The present invention relates to a method for producing a multi-layer material having anisotropic pores. It further relates to a multi-layer material that can be produced by the method according to the invention and to the use of a multi...  
WO/2013/081103
The present invention relates to a method for producing an auricular cartilage tissue by which an auricular cartilage tissue is capable of being produced which has a sufficient thickness and mechanical strength, and the auricular cartila...  
WO/2013/078770
A material is described herein. The material includes a multi-vinylsulfone containing molecule and a multi-nucleophile containing molecule. The material can form a hydrogel from an aqueous solution with dissolved multi-vinylsulfone and a...  
WO/2013/081648
A calcium-based bone cement formula having a powder component and a setting liquid component with a liquid to powder ratio of 0.20 ml/g to 0.50 ml/g is provided, wherein the powder component includes tetracalcium phosphate. The bone ceme...  
WO/2013/078790
A process utilizing PEEK material to manufacture a cerebral cranium bone, comprising the steps of: choosing corresponding original PEEK material according to patient electronic CT data provided by a hospital; heating the original PEEK ma...  
WO/2013/079469
It is provided a self-healing polymer network comprising transition metal thiolates, particularly thiolates of a transition metal that is able to self-assemble by metallophilic attractions, and more particularly Au(l), Ag(l), Cu(l) thiol...  
WO/2013/079646
The present invention relates to a homogeneous aqueous solution of injectable chitosan containing a chitosan having a degree of acetylation lower than 20%, said solution containing between 0.1 and 3.5% by weight of chitosan, said solutio...  
WO/2013/079443
The invention relates to a molded part for supporting bone regeneration, in particular the regeneration of a jawbone or jawbone section in a mammal, preferably a human, wherein the molded part is suitable for applying to the jawbone and ...  
WO/2013/075392
Provided are a method and a device for constructing a three-dimensional cellular microenvironment. The method comprises the following steps: 1) establishing a three-dimensional transparent sponge scaffold or a three-dimensional transpare...  
WO/2013/077897
An implant device for humans or mammals has a body structure having an exposed surface and one or more selected portions of the exposed surface having a bone formation enhancing 3-dimensional pattern. The exposed surface can be on exteri...  
WO/2013/077669
The present invention relates to: a production method for a ceramic powder derived from bird beak bone; a production method for a biomedical or industrial ceramic material comprising a ceramic powder derived from bird beak bone; and the ...  
WO/2013/077896
The present invention relates to a novel bone graft and methods for producing said graft. Said bone graft can be used for surgical, plastic and/or cosmetic bone replacement for a patient in need thereof. The bone graft is made of a scaff...  
WO/2013/077046
The purpose of the present invention is to obtain a surface modification member that can be favorably adhered to an implant material in a method for bonding together the surface modification member and the implant material by using a slu...  
WO/2013/078315
Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. Also described are methods for making and using these medical gr...  
WO/2013/077425
The present invention provides: [1] a method for producing a retinal tissue, characterized by comprising steps (1) to (3), i.e., (1) a first step of subjecting a pluripotent stem cell to floating culture in a serum-free culture medium co...  

Matches 551 - 600 out of 17,196