| Document |
Document Title |
|
WO/2023/216874A1 |
Disclosed in the present invention are a surface grafted cross-linked zwitterionic polymer coating, a preparation method therefor, and the use thereof. The present invention particularly relates to surface modification of medical instrum...
|
|
WO/2023/219968A1 |
A method for use in the manufacture of a medical implant is provided. A sandwich is formed, the sandwich including a fabric layer; a coating layer comprising a polymer configured to inhibit tissue growth thereon; a binding layer sandwich...
|
|
WO/2023/220041A1 |
A structurally enhanced composite graft is provided which comprises: at least one mechanical reinforcement component ("MRC") and at least one biostimulative tissue derived component ("BTC"). The composite graft may have a desired selecte...
|
|
WO/2023/217292A1 |
The present invention provides a piezoelectric/conductive composite conduit and a method for preparing same. The piezoelectric/conductive composite conduit has a length of 1-3 cm, an inner diameter of 2.5-3.5 mm, and a wall thickness of ...
|
|
WO/2023/220690A1 |
Provided herein are methods of inducing immune tolerance to graft cells in a human patient in need thereof comprising administering to the patient (i) the graft cells, (ii) a chimeric FasL protein conjugated to a hydrogel, and (iii) tran...
|
|
WO/2023/216099A1 |
An injectable hydrogel for treating heart failure and having myocardial tissue repair functionality, a method for preparing same, and use thereof. The hydrogel is prepared by chelating alginic acid and a multivalent cation. The hydrogel ...
|
|
WO/2023/216069A1 |
The present invention relates to a plastic orthopedic composition having erosion resistance, comprising: a powder composition comprising calcium sulfate hemihydrate, tricalcium phosphate, and hydroxypropyl methylcellulose; and a solvent ...
|
|
WO/2023/217283A1 |
Provided in the present invention is a hydrogel. The hydrodel comprises water, glycerol, cellulose ether, and a polymer. The polymer comprises a first polymer and a second polymer. The first polymer is polyacrylonitrile. The second polym...
|
|
WO/2023/216521A1 |
The embodiments of the present invention disclose a surface modification method for degradable pure magnesium or a degradable magnesium alloy, and a pure magnesium or magnesium alloy material, so as to solve the technical problems whereb...
|
|
WO/2023/216509A1 |
An implant prosthesis, comprising: a prosthetic body (10), a mounting part being provided on the prosthetic body (10); a drug carrying container (20), fixedly mounted on the mounting part, the drug carrying container (20) having an accom...
|
|
WO/2023/218412A1 |
The present invention relates to a scaffold comprising polycaprolactone (C6H10O2)n and glycine (C2H5NO2), characterised in that the scaffold is prepared by means of the joint electrospinning of the polycaprolactone and the glycine; and t...
|
|
WO/2023/219142A1 |
The purpose of the present invention is to provide tendon/ligament-like artificial tissue having sufficient strength. According to the present invention, tendon/ligament-like artificial tissue having sufficient strength is provided by: e...
|
|
WO/2023/219948A1 |
Systems and methods to eliminate or reduce the foreign body response (FBR) that occurs when a medical device is implanted into a patient. The FBR causes a chronic inflammatory response that leads to the encapsulation of a medical device ...
|
|
WO/2023/219498A1 |
The invention provides inter alia a method for enzymatic digestion of an extracellular matrix protein in a tissue sample, comprising the steps of: - providing an aqueous medium that comprises (i) a matrix metalloproteinase and (ii) a cat...
|
|
WO/2023/218455A1 |
The technology concerns a construct comprising at least one tissular region and at least one polymeric region for use as an implant.
|
|
WO/2023/215479A1 |
Viscoelastic hydrogel microparticles are used for repair of tissue defects and injuries or filling and occlusion of anatomical structures. These are administered as a microparticle suspension using a catheter, syringe, steerable catheter...
|
|
WO/2023/214361A1 |
The present invention relates to a method for decellularization of a tissue, the decellularized tissue matrix obtained by the method, and a scaffold comprising said matrix. The method for decellularization of a tissue according to the pr...
|
|
WO/2023/215757A1 |
Antimicrobial CaNCR peptide variants or CaNCR peptide variant multimers are disclosed along with compositions comprising the CaNCR peptide variants or CaNCR peptide variant multimers and transgenic or genetically edited plants or microor...
|
|
WO/2023/215885A1 |
In certain embodiments, the present disclosure provides methods of treating diseased or damaged tissue in a patient. In some forms the methods comprise introducing a photocurable composition to the diseased or damaged tissue, the photocu...
|
|
WO/2023/215329A1 |
In some aspects, the present disclosure pertains to injectable polysaccharide-based hydrogels that comprises an anionic polysaccharide, a cationic crosslinking agent and a hemostatic agent. In some aspects, the present disclosure pertain...
|
|
WO/2023/215883A1 |
In certain embodiments, the present disclosure provides adhesive compositions and medical graft materials comprising adhesive compositions. In some forms, such adhesive compositions comprise are photocurable and comprise one or more phen...
|
|
WO/2023/215872A1 |
Described are photocurabie liquid adhesives, kits for preparing photocurabie liquid adhesives, and methods for their preparation and use. Kits can include first and second components that can be mixed to prepare a photocurabie liquid adh...
|
|
WO/2023/213385A1 |
The invention relates to novel biocompatible Ta-Nb-Ti alloys, methods for preparing the same, and uses thereof.
|
|
WO/2023/212160A1 |
This disclosure relates to drug releasing implants. In certain embodiments, the implants release drugs from a biodegradable material. In certain embodiments, the implant is a low swelling hydrogel. In certain embodiments, the drug is an ...
|
|
WO/2023/210403A1 |
The present invention provides a method for evaluating the hair regeneration ability of dermal sheath cup (DSC) cells using the expression level of a gene related to smooth muscle differentiation as an indicator. The present invention al...
|
|
WO/2023/210775A1 |
The problem to be solved by the present invention is to provide: an immunoisolation device which can achieve both of the reduction in diffusion distance effective for the improvement in permeability of a substance such as a physiological...
|
|
WO/2023/210609A1 |
The purpose of the present invention is to provide a simple method for producing a cell sheet, wherein the cell sheet produced by the method is easily handled. The present invention provides a method for producing a cell sheet, the metho...
|
|
WO/2023/208607A1 |
A first aspect of invention relates a method for preparing a biodegradable biological tissue, preferably a collagen containing tissue. The (decellularized) biological tissue is first stabilized by a tissue water replacing material and th...
|
|
WO/2023/210765A1 |
The present invention addresses the problem of providing an immunoisolation device: that realizes both a reduction in diffusion distance, which is effective for improving the permeation of physiologically active substance, nutrients, etc...
|
|
WO/2023/209738A1 |
Provided in the present disclosure are biopolymer formulations comprising thiolated gelatin and methacrylated hyaluronic acid. Said formulations are useful for corneal applications, by way of example for treatment of disease of or damage...
|
|
WO/2023/212124A1 |
Biologics, including peptides, proteins, antibodies, nucleic acids (DNA and RNA), oligonucleotides, vaccines, or complex combinations of these substances, are important for treating various types of diseases and tissue and organ regenera...
|
|
WO/2023/206055A1 |
Provided are a modification and the use of silk fibroin. Calcium in silk fibroin or fibroin fibers is partially or completely removed, so as to obtain the modified silk fibroin with a broad-spectrum antioxidant effect. A method for prepa...
|
|
WO/2023/211147A1 |
The present invention relates to a method for preparing an extracellular matrix-induced self-assembly-based 3D printed artificial tissue, and artificial tissue prepared thereby, and provides: a method in which a self-assembly, formed by ...
|
|
WO/2023/210402A1 |
The present invention provides a method for evaluating the hair regeneration ability of dermal sheath cup (DSC) cells using a mitochondrial respiration level as an indicator. The present invention also provides a composition for hair reg...
|
|
WO/2023/212126A1 |
The present invention provides a soft tissue composite. The soft tissue composite comprises a first collagen fiber bundle of a first soft tissue isolated from a first donor and a polymeric material, and the first collagen fiber bundle in...
|
|
WO/2023/211728A1 |
Methods of promoting healing of a wound in a dermal location of a subject are provided. Aspects of the methods may include administering an effective amount of a Piezo inhibitor composition to the wound to promote healing of the wound, e...
|
|
WO/2023/208566A1 |
The present invention, inter alia, relates to a method for preparing a biological material for a medical application comprising exposing the biological material to a first liquid, for example comprising, by at least 10%, a component othe...
|
|
WO/2023/212637A1 |
Systems, methods, and devices include techniques for healing a bone void and/or regenerating a portion of bone by forming an exosome solution with one or more cell-derived exosomes and one or more cellular components. The one or more cel...
|
|
WO/2023/212416A1 |
Disclosed herein are various bioreactor devices that mimic the mammalian joint. The bioreactor device includes a series of bioreactor chambers that contain different components of the joint, such as bone, cartilage, synovium, and ligamen...
|
|
WO/2023/205854A1 |
The present invention relates to biocompatible hydrogels, in particular, biocompatible hydrogels for delivering a cell to a subject, wherein the hydrogel comprising a scaffold and an oxygen carrier.
|
|
WO/2023/211909A1 |
Compositions for local delivery of a drug to an intracranial region, such as brain tissue or a brain tumor. Methods for locally delivering drug or therapy to an intracranial region. Compositions may include a hydrogel in which a chemothe...
|
|
WO/2023/208968A1 |
The present invention relates to a guided bone regeneration device that is intended for the reconstruction of a buccal bone defect and is composed of an optionally micro-perforated smooth wall which is made of titanium and has a shape th...
|
|
WO/2023/204122A1 |
[Problem] The purpose of the present invention is to provide a method for producing a hydroxyl-group- and (meth)acryl-group-containing siloxane at high purity and high yield. [Solution] The present invention provides a method for purifyi...
|
|
WO/2023/205265A1 |
The present disclosure provides improved polymer compositions, such as GelMA polymer compositions. In certain embodiments, the improved polymer compositions can be used for delivering one or more therapeutic agents, such as cells, to a t...
|
|
WO/2023/205051A1 |
Compositions, methods, and applications for single component systems for the formation of in situ hydrogels are described. The single component systems are effective for forming stable, single solutions containing precursors providing bo...
|
|
WO/2023/205370A1 |
Disclosed herein are apparatuses comprising one or more channels defining a luminal space, wherein the luminal space is defined by an inner wall of fibrous basement membrane material, as well as methods of their manufacture and use.
|
|
WO/2023/204434A1 |
According to the present invention, a decellularized tissue supplement is prepared by: a preparation step for preparing tissue of a non-human mammal; a pretreatment step for pretreating the tissue; a first inactivation step for inactivat...
|
|
WO/2023/204424A1 |
The present invention relates to a technology relating to an implant abutment and, more specifically, to an implant abutment absorbing external shock and a manufacturing method thereof, wherein when an implant abutment made of titanium (...
|
|
WO/2023/205141A1 |
Disclosed are compositions and kits useful for bone repair and reconstruction of bone defects such as bone voids and fractures. The compositions can include two reactive components that when mixed together form a polythiourethane that cu...
|
|
WO/2023/205519A1 |
A method for producing a microfluidic device, the method comprising: producing a first housing portion and a second housing portion; securing the second housing portion to the first housing portion; enclosing a three-dimensional biomater...
|
