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Matches 1 - 50 out of 37,792

Document Document Title
WO/2019/008106A1
The present invention relates to a three-dimensional macroporous scaffold structure comprising cross-linked cationized bovine serum albumin. The invention also relates to a production method for the three-dimensional macroporous scaffold...  
WO/2019/009428A1
[Problem] To provide a medical implant of good biocompatibility. [Solution] Provided is an implant used for joining to biological tissue, including bone and teeth, the implant being made of a metal selected from titanium or titanium allo...  
WO/2019/010304A1
Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral layer. Other formulations include a ca...  
WO/2019/009265A1
The present invention addresses the problem of providing a medicine with which it is possible to simply treat and/or prevent retinal degenerative diseases associated with photoreceptor degeneration, including retinitis pigmentosa. The so...  
WO/2019/008192A1
The invention relates to a biodegradable surface coating for suppressing/delaying arrosion/corrosion or degradation of solid materials for medical applications and their integration into cell aggregates.  
WO/2019/010464A1
The present invention provides compositions and methods for improving cardiac function. Specifically, the present invention provides compositions and methods for treating a subject having a disorder or condition associated with aberrant ...  
WO/2019/007423A1
An implantable apparatus, comprising at least one corrodible zinc-containing portion, wherein a content range of zinc in the at least one zinc-containing portion is [30, 50) wt.% and zinc in the zinc-containing portion is an amorphous st...  
WO/2019/010485A1
This disclosure provides method for treating fibrosis in a patient in need thereof, comprising administering to the patient an effective amount of a bioconjugate comprising a glycan bonded to at least one peptide comprising at least one ...  
WO/2019/008552A1
This application discloses the production of a Bio MicroElectroMechanical System device (BioMEMs) targeted to the promotion of bone regeneration by means of coating a biomedical metallic substrate with a functionalized ferroelectric /pie...  
WO/2019/008381A1
This invention relates to a composite material which is a copolymer of at least (i) a functionalised carbon nanoparticle, (ii) a polyol, (iii) a compound comprising at least two isocyanate groups, wherein the functionalised carbon nanopa...  
WO/2019/005943A1
This disclosure relates compositions comprising upconverting core-shell nanocrystals and photoactive compositions and methods using these compositions to modify treat myopia and other ocular conditions. In some cases, the methods use nea...  
WO/2019/006256A1
Methods of preparing calcification-resistant bioprosthetic tissue include providing fresh biological tissue, cross-linking the tissue, treating the cross-linked tissue with an alcohol for a time sufficient to allow the alcohol to be diff...  
WO/2019/002369A1
A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, said method comprising: i) providing a crosslinked glycosaminoglycan, wherein said glycosaminoglycan is at least partially N-deacetylated such t...  
WO/2019/004382A1
Provided are: an immunoisolation membrane which is resistant to a drop in substance permeability, and which can be produced inexpensively; and a method for producing same. This immunoisolation memrane contains a surface-modified porous m...  
WO/2019/002912A1
The present technology provides nanocomposite compositions that include about 0.1 wt.% to about 40 wt.% of nanoparticles having a net cationic charge by weight of the composition; about 0.1 wt.% to about 50 wt.% of one or more gelling ag...  
WO/2019/004378A1
Provided is a transplant chamber comprising an immunoisolation membrane containing a porous membrane in at least part of the boundary between the interior and the exterior, wherein the porous membrane contains a polymer, and within the m...  
WO/2019/004809A1
A mixture and combination comprising poly(ethylene glycol diacrylate), 1-vinyl-2-pyrrolidone and a photoinitiator, as well as the same mixture with a ceramic reinforcement, namely hydroxyapatite. A photopolymeric resin useful for 3D prin...  
WO/2019/004793A2
Provided is a method for manufacturing artificial skin, the method comprising the steps of: mixing fibroblasts and collagen to form a dermis simulation layer; applying keratinocytes onto the dermis simulation layer, followed by culturing...  
WO/2019/004381A1
Provided are: a transplant chamber which is highly durable and which efficiently ensures an internal space thereof, and which can maintain biological substances encapsulated therein for long periods; and a method for producing same. This...  
WO/2019/006380A2
A prosthetic heart valve includes a first upper frame portion and a stent frame connected to the first upper frame portion via at least two stent frame extensions. The stent frame includes a base and at least two stent posts extending up...  
WO/2019/006383A2
A transcatheter prosthetic heart valve includes a stent frame and at least one sheet of leaflet material formed in to a tube, which includes a lower portion disposed on an exterior of the stent frame and an upper edge portion disposed wi...  
WO/2019/005848A1
Hyaluronic acid and silk protein fragments based tissue fillers and methods of the same are provided herein.  
WO/2019/001784A1
The present invention relates to a method of preparing a sterilized injectable hydrogel composition, comprising the steps: a) providing an amide crosslinked glycosaminoglycan, b) swelling the amide crosslinked glycosaminoglycan in a solu...  
WO/2019/002148A1
The present invention relates to a method for producing cartilaginous tissue by means of selection of and sampling from chondrocytes or spheroids and the use thereof as pharmaceutical composition, drug or transplant. The invention specif...  
WO/2019/005802A1
Techniques to fabricate and use a nanocomposite coating that includes one or more nanotubes such as carbon nanotubes are disclosed. In some examples, a guidewire may include the nanocomposite material. The guidewire is immune to electrom...  
WO/2019/006013A1
A medical implant has a hierarchical surface roughness and includes an implant body, which includes a combination of meso-scale surface features, micro-scale surface features, and nano-scale surface features.  
WO/2019/006317A1
Provided herein, inter alia, are non-crosslinked polymers that possess thermoresponsive properties. These polymers possess a cleavable bond that breaks under certain conditions The disclosure also provides pharmaceutical compositions con...  
WO/2019/003206A1
The present document describes a composition and pharmaceutical composition comprising gelatin derived from a cold-adapted aquatic species, chitosan, agarose and glycerol. Further, the present document discusses a process for manufacturi...  
WO/2019/004446A1
The present invention addresses the problem of providing an excellent treatment agent for lysosomal storage disease. Provided is a treatment agent for lysosomal storage disease, containing a cellular structure that includes multiple bioc...  
WO/2019/003090A1
The present invention relates to a coating comprising functionalised magnetic or metallic nanoparticles linked to bacteriophages, proteins or peptides having antibacterial action and being derived from same. The antibacterial coating can...  
WO/2019/004380A1
The present invention provides a chamber for implantation which has an immunoisolation membrane at the boundary between the inside and outside of the chamber for implantation. The immunoisolation membrane comprises a porous membrane. The...  
WO/2019/006430A1
The present invention is an improved implant made from regenerative tissue or natural tissue, methods of making the implant, and methods of using the implant.  
WO/2019/004361A1
The present invention provides a method for swiftly producing a layered cell sheet that is non-invasively obtained and is utilizable for transplantation, etc., the method including (1) a step of applying a centrifugal force to a first ce...  
WO/2019/004377A1
Provided are: a transplant chamber having an immunoisolation membrane including a porous membrane at at least part of the boundary between the interior and the exterior, wherein the porous membrane contains a polymer, and has, within the...  
WO/2019/004379A1
The present invention provides: a flexible implantation chamber which is a plane-shaped implantation chamber which can stably hold a biological constituent and has a structure in which immunoisolation membranes face each other; and an im...  
WO/2019/001472A1
A branched polyglycol epoxy derivative cross-linked sodium hyaluronate gel, preparation therefor, and an application thereof. A cross-linking agent used in the prepared cross-linked sodium hyaluronate gel is a polyglycol epoxy derivative...  
WO/2019/006328A1
The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the ...  
WO/2019/002277A1
The invention relates to a magnesium alloy which comprises: Zn: 0.5 - 2 wt%, Mn: 0.2 - 1 wt%, Ca: 0.1 - 2 wt%, wherein the magnesium alloy comprises 0.6 wt% or more Mn or 0.6 wt% or more Ca, between 0.5 wt% and 1,5 wt% Mn and Ca in sum, ...  
WO/2018/232445A1
A method for preparing a scaffold, said method comprising the steps of providing a solution comprising fibre-forming molecules; subjecting the solution to a cooling medium to establish a temperature difference at an interface between the...  
WO/2018/234972A1
The present invention relates to a polymeric device, for the ocular release of drugs, composed of coaxial polymeric nanofibres that preferably comprise polycaprolactone, gelatine, polyvinyl alcohol and an angiogenesis inhibitor, which is...  
WO/2018/237179A1
This document provides methods and materials for treating a mammal (e.g., a human) having one or more stenotic blood vessels. For example, amnion coated balloons that can be used in balloon angioplasty are provided.  
WO/2018/235984A1
The present invention relates to an integral biomaterial for regeneration of a bone tissue and a fabrication method therefor and, more particularly, to an integral biomaterial for regeneration of a bone tissue, comprising an infrastructu...  
WO/2018/236604A1
A method and material composition of a highly porous material that is applied to an object, such as a biomaterial implant and biomedical device, is described. The method involves forming a bijel mixture that is exposed to at least an out...  
WO/2018/236835A1
Provided herein are novel devices for the formation of arteriovenous fistulas, which may aid subjects in need of hemodialysis. The novel devices are provided in a non-surgical procedure, greatly decreasing the cost and increasing the con...  
WO/2018/233767A1
The invention relates to a coating or a body provided with a coating. The coating is at least partly made of a composite material which comprises a porous support that has a metal core surrounded with a metal oxide. According to the inve...  
WO/2018/235786A1
Provided are: a means for identifying a cell which is suitable for transplantation into the cornea; and a means for producing a cell population, which is suitable for transplantation into the cornea, by using the aforesaid means. A metho...  
WO/2018/235745A1
The present invention pertains to a biocompatible long-fiber nonwoven fabric including, as the main component, a biocompatible polymer, wherein biocompatible long fibers constituting the biocompatible long-fiber nonwoven fabric have a fi...  
WO/2018/237232A1
An adhesive skin patch with a support liner comprises at least a strip drug product and a release liner longer than the drug product. The support liner includes a backing film and an adhesive layer; the drug product is quadrilateral with...  
WO/2018/227264A1
The inventions relate to medicine and may be used in neurosurgery, traumatology, neurology, rehabilitation. The aim of the claimed group of disclosures is to create the implant suitable for treatment for nerve tissue injuries of various ...  
WO/2018/231636A1
Provided is an implant configured to fit at or near a bone defect to promote bone growth. The implant comprises an oxysterol uniformly disposed in an acellular tissue matrix (ATM). The acellular tissue matrix can be porcine collagen, whi...  

Matches 1 - 50 out of 37,792