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Matches 1 - 50 out of 37,423

Document Document Title
WO/2018/188989A1
The invention relates to a native bone substitute material for promoting osteogenesis, comprising native bone composite material having a hydroxyapatite structure and collagen, the bone substitute material being obtainable by atelopeptid...  
WO/2018/191527A1
The invention relates to biodegradable, metal alloys, methods for their preparation and applications for their use. The alloys include magnesium and other components, such as, yttrium, calcium, zirconium, and zinc. These elements are all...  
WO/2018/190687A1
The present invention relates to a method for manufacturing spherical ceramic granules, comprising: (a) a step of preparing an organic and inorganic composite liquid; (b) a step of manufacturing spherical granules by injecting, into an e...  
WO/2018/190113A1
An objective of the present invention is to provide a simple, novel method for forming artificial enamel in which multiple hydroxyapatite nanorods are densely gathered and aligned in the same crystal orientation. An artificial enamel (st...  
WO/2018/189185A1
The present invention relates to a dental implant made of a ceramic material comprising an implant surface having at least partially a contact angle of less than 20°, said implant surface being at least partially covered by a protective...  
WO/2018/188279A1
Disclosed are a novel artificial joint alloy and a smelting process therefor, wherein the alloy can also be used for other medical human body implants. The novel artificial joint alloy is non-magnetic and non-toxic, with the properties t...  
WO/2018/189159A1
The invention relates to an implant component having a male and/or female frictional connection section and a functional section, wherein: the frictional connection section has a first coating and the functional section has a second coat...  
WO/2018/191681A1
The present disclosure provides for a medical device or a substrate coated with polydopamine which is further linked to ligands such as antibodies and/or antibody fragments. The polydopamine coating and the ligands may be linked through ...  
WO/2018/191274A1
Embodiments of the present disclosure encompass systems and methods for in-situ/in vivo, bottom-up tissue generation for wound repair, repair of tissue defects, and the like. Embodiments of the systems of the present disclosure include m...  
WO/2018/190688A1
The purpose of the present invention is to provide organic and inorganic composite granules of a uniform size and a production method therefor. To this end, the present invention provides inorganic and organic composite granules which ar...  
WO/2018/189384A1
The present invention relates to a regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, the present invention relates to a connective tissue regenerative material, preferably ...  
WO/2018/191622A1
Provided are compositions comprising a viral vector and a VEGF gene or a fragment thereof, and methods of using the compositions for the treatment of an injury of a fibrous connective tissue.  
WO/2018/191672A1
This invention provides for a network of cell-derived microfilaments. Also provided are methods of producing a network of microfilaments via culturing cells in a matrix support and cell culture medium wherein the cells proliferate and fo...  
WO/2018/187752A1
Provided herein are methods for the controlled, independent modification of the surface of titanium-based materials and compositions generated thereby. The methods allow for the alteration of multiple surface characteristics including ge...  
WO/2018/187407A1
The invention relates to biomimetic, biodegradable composites including a magnesium (Mg) alloy mesh and a polymer/extracellular matrix (ECM). These hybrid composites, more particularly, are useful for the fabrication of medical implant d...  
WO/2018/186420A1
The present invention addresses the problem of providing a cell population which includes mesenchymal stem cells having a strong immunosuppressive effect, a production method therefor, mesenchymal stem cells having a strong immunosuppres...  
WO/2018/187286A1
An injectable hydrogel composition that forms a porous gel rapidly after injection fro tissue engineering. The composition comprises a biodegradable, biocompatible, gelling polymer, that is optionally reverse-gelling; an Extra cellular m...  
WO/2018/187782A1
Provided herein are methods for the controlled, independent modification of the surface of polymer-based materials and compositions generated thereby. The methods include use of low temperature plasma for surface modification. The method...  
WO/2018/185770A1
The present invention relates to implants comprising a deformable body formed of a polymer comprising functional groups capable of cross-linking to form a cross-link; said body provided in a first configuration which is cross-linked to a...  
WO/2018/185755A1
A minimally invasive system using a surgical robot as a three-dimensional printer for fabrication of biological tissues inside the body of a subject. A preoperative plan is used to direct and control both the motion of the robot and the ...  
WO/2018/185650A1
The present invention relates to a thermoplastic polyurethane composite comprising functionalised nanoparticles incorporated into a polyurethane matrix, and to the synthesis method thereof. The method comprises melting a diisocyanate in ...  
WO/2018/187530A1
The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compou...  
WO/2018/187780A1
This document describes systems and method of embedded printing for additive manufacturing. A print material is printed into a support material. The print material and the support material each have a fluid phase and a solid phase. The p...  
WO/2018/187595A1
This document describes a process of producing gel microparticles, which are consistent in size and morphology. Through the process of coacervation, large volumes of gel microparticle slurry can be produced by scaling up reactor vessel s...  
WO/2018/185302A1
The present invention relates to moulding or casting processes for producing solid objects. The process involves a suspension which comprising a liquid non-aqueous substance and a material such as a ceramic. The suspension is liquid at e...  
WO/2018/187184A1
An injectable therapeutic angiogenic material includes an in situ gelling hyaluronic acid-based hydrogel containing a first plurality of clustered VEGF heparin nanoparticles in which VEGF is immobilized to the heparin nanoparticles and a...  
WO/2018/186419A1
The present invention addresses the problem of providing a cell population which includes mesenchymal stem cells having a high angiogenic potential, a production method therefor, mesenchymal stem cells having a high angiogenic potential,...  
WO/2018/186418A1
The present invention addresses the problem of providing a cell population which includes attached cells derived from fetal appendages and has a low differentiation potential, a production method therefor, and a pharmaceutical compositio...  
WO/2018/187756A1
Provided herein are magnesium-based sponges and foams and methods for surface modification to enhance bioactivity. The magnesium-based sponges and foams may be useful as tissue or bone grafts which promote cellular adhesion and osseointe...  
WO/2018/186953A1
Described are macro-capsules and barriers that can be used to prepare therapeutic cell implants, methods of encapsulating therapeutic cells, and methods of using the encapsulated cells in the treatment of disease.  
WO/2018/187380A1
The invention is directed to three-dimensional, engineered, bioprinted biological tissue constructs exhibiting a liver disorder, methods of making the constructs, and use of the constructs in assays, such as drug testing and molecular di...  
WO/2018/185313A1
The invention relates to a coating comprising a hydrogel layer of a hydrogel of a polysaccharide and polymer brushes attached to the hydrogel layer. The invention also relates to a process for making the coating according to any one of t...  
WO/2018/183856A1
A method of forming cured microparticles includes providing a poly(glycerol sebacate) resin in an uncured state. The method also includes forming the composition into a plurality of uncured microparticles and curing the uncured micropart...  
WO/2018/183809A1
The present invention includes a fluid interface system for use in medical implants. The fluid interface system of the present invention can include one or more fluid interface channels disposed within an implant. The fluid interface sys...  
WO/2018/181960A1
The present invention relates to a method for producing an osteoblast cluster from human iPS cells, the method comprising: (1) a step for inducing the formation of embryoid bodies by non-adhesively culturing undifferentiated human iPS ce...  
WO/2018/181245A1
[Problem] To provide an adhesive for hard tissue bonding that has an adequate pot life and exceptional biocompatibility and is replaced by bone over time, and an adhesive kit for hard tissue bonding. Also, to provide a bone cement that h...  
WO/2018/176138A1
A coating composition comprises an aqueous solution comprising at least one vinyl carboxylic acid monomer and at least one neutral monomer, wherein the at least one neutral monomer has a glass transition temperature of less than about 10...  
WO/2018/183946A1
Transgenic silkworms stably expressing synthetic spider silk genes or composite silkworm/spider silk genes are disclosed. The exogenous spider silk genes are stably intergrated into a defined site of the fibroin heavy chain intron or a f...  
WO/2018/181824A1
Provided are an information processing device, a system, an information processing method and a program capable of generating a material for regenerative medicine that is optimized to the situation. This information processing device is ...  
WO/2018/178859A1
Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI lay...  
WO/2018/182536A1
Systems and methods for continuous printing of a three-dimensional (3D) object are provided. The system includes a resin tank, an optical image source, a support fluid reservoir and a pumping structure. The resin tank is where the 3D obj...  
WO/2018/178266A1
The present invention relates to a carrier composition for particulate and granular bone substitute materials which is a hydrogel comprising a mixture of ethylene oxide(EO)-propylene oxide(PO) block copolymers and silica nanoparticles em...  
WO/2018/183801A1
Disclosed herein is a prosthesis that may be used to replace standard prosthetic material used in osteo-odonto-keratoprosthesis (OOKP) surgery. The disclosed prosthesis is not prepared from tissue removed from a patient's tooth and jaw b...  
WO/2018/181918A1
The objective of the present invention is to provide a cylindrical structure with which excellent puncture resistance can be imparted while maintaining the flexibility of a base material, by covering the base material using a covering ma...  
WO/2018/181832A1
This photocurable composition for use in optical shaping contains: a (meth)acrylic monomer (X) which has a weight-average molecular weight of 400-580 and is at least one selected from di(meth)acrylic monomers having two aromatic rings an...  
WO/2018/182278A1
The present invention relates to a porous microsphere including a mussel adhesive protein, and a method for manufacturing same. A porous microsphere including a mussel adhesive protein according to the present invention can be injected i...  
WO/2018/179358A1
Provided is an antibacterial biological implant capable of stable display of excellent antibacterial properties over time. In this method for producing an antibacterial biological implant, an antibacterial biological implant 1 is obtaine...  
WO/2018/179357A1
Provided is an antibacterial biological implant capable of stable display of excellent antibacterial properties over time. This antibacterial biological implant 1 is provided with a substrate 2 made of a metal material and an anodized co...  
WO/2018/182462A1
The invention relates to a method for creating a coating on medical implantable devices placed inside a recipient's body and having at least one surface in contact with blood, in particular on vascular prostheses made of a polymer materi...  
WO/2018/182834A1
The three-dimensional lattice structures disclosed herein have applications including use in medical implants. Some examples of the lattice structure are structural in that they can be used to provide structural support or mechanical spa...  

Matches 1 - 50 out of 37,423