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WO/2019/007423A1 |
An implantable apparatus, comprising at least one corrodible zinc-containing portion, wherein a content range of zinc in the at least one zinc-containing portion is [30, 50) wt.% and zinc in the zinc-containing portion is an amorphous st...
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WO/2019/007400A1 |
Disclosed are a biodegradable film, a preparation method and the use thereof. The preparation method for the biodegradable film comprises placing a mobile phase made of a film-forming raw material in a dry, flat-bottomed container, solid...
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WO/2018/237166A1 |
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and ot...
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WO/2018/233767A1 |
The invention relates to a coating or a body provided with a coating. The coating is at least partly made of a composite material which comprises a porous support that has a metal core surrounded with a metal oxide. According to the inve...
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WO/2018/197341A1 |
A fluorinated aromatic sulfone polymer [polymer (F-PS)] comprising: recurring units [units (A)] derived from at least one dihalo-diaryl sulfone [monomer (A)]; recurring units [units (B)] derived from at least one aromatic diol [monomer (...
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WO/2018/193779A1 |
Provided is an article to be used in contact with a living body or a biological sample, wherein the article has a first film and a second film, the first film including an amorphous carbon film in which the proportion of the number of sp...
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WO/2018/194947A1 |
A suturing device includes a handle, an elongate body, an actuator and a needle holder. The handle includes a proximal handle end and a distal handle end. The elongate body connects with the handle and includes a proximal end portion and...
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WO/2018/187756A1 |
Provided herein are magnesium-based sponges and foams and methods for surface modification to enhance bioactivity. The magnesium-based sponges and foams may be useful as tissue or bone grafts which promote cellular adhesion and osseointe...
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WO/2018/182462A1 |
The invention relates to a method for creating a coating on medical implantable devices placed inside a recipient's body and having at least one surface in contact with blood, in particular on vascular prostheses made of a polymer materi...
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WO/2018/178394A1 |
A cardiovascular graft is provided with highly reduced thrombogenicity. The cardiovascular graft is an electrospun non-woven mesh produced from supramolecular polymers with large diameter fibers. The cardiovascular graft can be implement...
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WO/2018/168171A1 |
The present invention pertains to a method for producing an artificial lung having a plurality of porous hollow fiber membranes for gas exchange, the plurality of porous hollow fiber membranes for gas exchange including: an outer surface...
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WO/2018/165368A1 |
A cardiac pump and an assist system is provided to increase blood ejection from a compromised heart. An implantable cardiac pump acting as an assist device includes an attachment system and locating features that enable a minimally invas...
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WO/2018/159580A1 |
The present invention provides pentosan polysulfate having a weight average molecular weight of 5000 or less and an acetyl group content of 0-2.0 mass% or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solva...
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WO/2018/139665A1 |
Provided is a use for a peptide in surface-treating a medical device or medical material to be used in contact with blood, with which it is possible to obtain a medical device or medical material that can achieve highly efficient vascula...
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WO/2018/003822A9 |
[Problem] To provide a slipperiness-imparting agent capable of imparting durable slipperiness (in particular, slipperiness when wet). [Solution] The present invention was completed upon the discovery that a slipperiness-imparting agent c...
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WO/2018/091099A1 |
The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material an...
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WO/2018/086556A1 |
Disclosed is a polymer for capturing or separating leucocytes. The polymer is prepared by a polymerization reaction of monomers containing an amido and hydroxyl. The monomer containing an amido and hydroxyl has the structure of formula (...
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WO/2018/083623A1 |
The present invention relates to the medical industry. In particular, the invention relates to a functionalised polyvinyl chloride (PVC) polymer for medical use, which is flexible and compatible with blood. The invention relates specific...
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WO/2018/071458A1 |
A sheath introducer facilitates the insertion of a catheter into a peripheral artery. The sheath introducer comprises longitudinally extending exterior and interior surfaces, the interior surface defining a lumen in which blood flow occu...
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WO/2018/061916A1 |
The purpose of the present invention is to provide: a copolymer that is capable of being immobilized on a base material while maintaining a high antithrombotic property persistently without having to introduce heparin or an anticoagulant...
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WO/2018/056018A1 |
The purpose of the present invention is to provide: a simple method by which a porous substrate comprising a bioabsorbable polymer that contains heparin is produced without the use of surfactants; a porous substrate comprising a bioabsor...
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WO/2018/043209A1 |
The purpose of the present invention is to provide a medical material capable of suppressing adhesion of platelets and proteins even when in contact with biological components such as blood for an extended period of time. The present inv...
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WO/2018/034477A1 |
The present invention relates to a silk suture with enhanced tensile strength and knot strength and a method for preparing the same. The silk suture according to the present invention is treated with 4-hexylresorcinol, so that a silk sut...
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WO/2018/025979A1 |
The purpose of the present invention is to provide a copolymer having exceptional water permeability, platelet adherence suppression, and protein adherence suppression, and to provide a separation membrane, a medical device, and a medica...
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WO/2018/023840A1 |
An artificial blood vessel and manufacturing method thereof. The method comprises: using a 3-[(3-cholamidopropyl)-diethylamino]-propanesulfonic acid reagent to chemically decellularize a cellular component of a vessel from an autologous ...
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WO/2018/025772A1 |
The purpose of the present invention is to provide a biological component adhesion-suppressing material that is able to suppress adhesion of platelets and proteins even when coming into contact with blood, etc. The present invention comp...
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WO/2018/003821A1 |
Provided are: a copolymer having sufficient biocompatibility for use in medical material applications; and a method for forming a cross-linked body that uses said copolymer and imparts biocompatibility to a substrate surface. More specif...
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WO/2017/221172A2 |
A process for producing a medical device (100), which is coated with a thin film based on carbon, comprises the steps of: - positioning a medical device to be coated inside a processing chamber (3), in which there is provided a target el...
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WO/2017/218987A1 |
A highly portable advanced adult and pediatric compact ECLS system is based around an integrated pump-oxygenator. The system includes a central a blood inlet and flow path extending along a general longitudinal axis of the system; a pump...
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WO/2017/210537A1 |
Methods of increasing immunogenic cell viability by administering an immunogenic animal cell and a complement inhibitor to a subject are described. Immunogenic animal cells such as stem cells protected with a coating of complement inhibi...
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WO/2017/190290A1 |
A medical polymer device comprising a biodegradable polymer is provided, wherein the biodegradable polymer has a crystallinity of about 10％to about 80％, and preferably from about 20％to about 60％, wherein the medical polymer devic...
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WO/2017/190152A1 |
Sustained release drug delivery devices including scaffolds comprising combinations of anti-connexin, anti-gap junction, anti-hemichannel and/or other agents, for example, anti-connexin 26 and anti-connexin43 polynucleotides or peptidomi...
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WO/2017/189480A1 |
The present invention relates to novel compositions and methods for reducing or eliminating the thrombogenicity of a graft by modifying the graft with a cell-derived extracellular matrix lacking thrombospodin-2 (TSP2-null ECM) to render ...
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WO/2017/172469A1 |
A medical needle may include a lumen coating configured to reduce surface energy of the lumen-facing/ lumen defining surface, in a manner effective to slow and/or reduce coagulation of biomaterial (particularly blood) that contacts the n...
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WO/2017/156592A1 |
The present disclosure relates to anti-fouling and/or anti-thrombotic medical devices, methods for reducing fouling and/or thrombosis associated with medical devices, and methods for coating substrates to reduce fouling and/or thrombosis...
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WO/2017/150000A1 |
The objectives of the present invention are: to find a biocompatible material which has excellent film formation properties and resistance to water dissolution and is able to be easily coated to various bases, while having excellent anti...
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WO/2017/143419A1 |
The invention describes a method for producing nanozeolites with hemostatic activity comprising a nanoscale zeolite material derived from the faujasite family, treated with calcium, magnesium, barium and silver cations by an ion exchange...
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WO/2017/147491A1 |
The invention provides a method of producing a population of human Schwann cells. The method comprises (a) incubating human fascicles with one or more mitogens for a priming period of three to fourteen days to produce primed fascicles, (...
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WO/2017/146102A1 |
A device that includes: a substrate; and a hydrophilic polymer layer that comprises a hydrophilic polymer that has a hydroxyl group. The hydrophilic polymer layer that has a hydroxyl group is adhered to at least one portion of the surfac...
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WO/2017/146101A1 |
A device that includes: a substrate; and a gel layer that comprises a hydrophilic polymer that has a hydroxyl group. The gel layer is adhered to at least one portion of the surface of the substrate at a thickness of 1-3000 nm. The elasti...
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WO/2017/139224A1 |
Various embodiments relate to catheter locking solutions and catheter locking therapies with use of trisodium citrate and ethyl alcohol, and in particular 4.0 to 15.0 weight/volume % trisodium citrate as an anticoagulant component and/or...
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WO/2017/136268A1 |
Various embodiments of the present invention include a cannula coated or compounded with a material to extend the wear time for a patient by reducing inflammation and therefore increasing the time that the cannula may remain inserted, th...
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WO/2017/134049A1 |
Implantable medical product, comprising a basic body and an imidazole derivative in the form of its free base; wherein said basic body has on its polymeric surface a layer containing the imidazole derivative as an active ingredient, whic...
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WO/2017/131416A2 |
The present invention relates to a suturing thread for providing a more efficient lift procedure, and provides a suturing thread for a facelift and a body lift, wherein the suturing thread is made of a polymer material and has a pluralit...
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WO/2017/095782A1 |
In some embodiments, the present invention provides compositions including silk fibroin, at least one hydrophilic agent, and at least one catechol donating agent, wherein the at least one hydrophilic agent and at least one catechol donat...
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WO/2017/066242A1 |
A biocidally active polymer composition formed from an oligomeric or polymeric additive and a thermoplastic polyurethane polymer is disclosed. The biocidally active polymer may further include a non-fouling and/or non-thrombogenic polyme...
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WO/2017/047680A1 |
Provided is a photoreactive azide-containing copolymer having sufficient biocompatibility for use in medical material applications. Further provided is a production method that enables the photoreactive azide-containing copolymer to be s...
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WO/2017/039336A1 |
The present invention relates to a method for preparing a high-functional suture yarn coated with hyaluronate and a high-functional suture yarn prepared therefrom and, more specifically, to a method for preparing a high-functional suture...
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WO/2017/034223A1 |
The present invention relates to a silk suture with enhanced tensile strength and knot strength, and a manufacturing method therefor. The silk suture according to the present invention has enhanced tensile strength, knot strength and bio...
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WO/2017/027931A1 |
The present invention relates to the coating of a range of functional heparins onto the surface of a substrate for which hemocompatibility is a key functional characteristic, such that the functionality of the functional heparin is maint...
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