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WO/2012/017337 |
The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in that it comprises at least two layers, each...
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WO/2012/001532 |
A medical device includes a substrate having at least a portion thereof functionalized with at least one reactive member and a chemotactic agent functionalized with at least one complementary reactive member, wherein the at least one rea...
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WO/2011/146292 |
Medical delivery devices include a needle and a flexible compressible impermeable tube attached to the needle. The compressible tube has an open interior channel. The device is adapted to releasably hold a length of a medical implant in ...
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WO/2011/131887 |
The present invention relates to a method for manufacturing a hemocompatible material comprising a synthetic substrate and animal biological tissue, according to which said animal biological tissue is dehydrated and adhered to said synth...
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WO/2011/118818 |
Disclosed is a novel amidine derivative that exhibits activated blood coagulation factor X inhibitory activity, a method for producing the same, a production intermediate thereof, and a pharmaceutical composition containing said amidine ...
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WO/2011/118818 |
Disclosed is a novel amidine derivative that exhibits activated blood coagulation factor X inhibitory activity, a method for producing the same, a production intermediate thereof, and a pharmaceutical composition containing said amidine ...
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WO/2011/110684 |
There is describedinter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an anti-coagulant entity capable of interacting with mammalian blood to preve...
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WO/2011/103486 |
A vena cava filter catheter includes a catheter having a lumen disposed therethrough and at least one strand of biocompatible wire. The at least one strand has a first state in which the at least one strand has an elongate geometry suita...
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WO/2011/103486 |
A vena cava filter catheter includes a catheter having a lumen disposed therethrough and at least one strand of biocompatible wire. The at least one strand has a first state in which the at least one strand has an elongate geometry suita...
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WO/2011/093932 |
The present invention describes the design and development of new fibrinogen and fibrinogen derived products with significantly reduced binding to bacteria while retaining normal physiological functions by using modified fibrinogen amino...
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WO/2011/093932 |
The present invention describes the design and development of new fibrinogen and fibrinogen derived products with significantly reduced binding to bacteria while retaining normal physiological functions by using modified fibrinogen amino...
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WO/2011/083154 |
The present invention relates to a dry powder fibrin sealant which comprises a mixture of fibrinogen and thrombin for use in surgery, trauma and other wounds or injuries. It further relates to novel formulations comprising said dry powde...
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WO/2011/083815 |
Disclosed is a method for coating the inner surface of a medical tube made from poly(vinyl chloride) and containing a plasticizer with an anti-thrombotic material comprising a specific (meth)acrylate copolymer, whereby the anti-thromboti...
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WO/2011/078208 |
Provided is a hydrophilic polymer compound which is capable of interfering with blood coagulation in both the primary hemostasis step wherein platelets participate and the blood clot formation step wherein blood coagulation factor partic...
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WO/2011/063940 |
The present disclosure relates to a continuous process for selectively modifying the lumen surface of a hollow fiber membrane using a plasma, an apparatus for carrying out the process and to hollow fiber membranes obtainable by the proce...
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WO/2011/060554 |
The present description relates to a presolidified implant composition, a method for its preparation, and a use of said implant composition for repairing tissue of a patient wherein the implant comprises a blood component, a salt and a p...
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WO/2011/060066 |
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WO/2011/059123 |
The present invention relates to a heparin compound bound to an adhesive material, a preparation method thereof, a solid surface coating agent containing the same as an active ingredient, and a coating method of a solid surface using the...
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WO/2011/006507 |
The present invention relates to preparation of a polymer coating comprising or consisting of polymer chains comprising or consisting of units of 2-methoxyethyl acrylate synthesized by Surface-Initiated Atom Transfer Radical Polymerizati...
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WO/2011/006507 |
The present invention relates to preparation of a polymer coating comprising or consisting of polymer chains comprising or consisting of units of 2-methoxyethyl acrylate synthesized by Surface-Initiated Atom Transfer Radical Polymerizati...
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WO/2010/150874 |
A surgery instrument which can be used for both general surgery and endoscopic surgery and consists of a material having not only liquid-absorbing properties and liquid-retaining properties but also excellent liquid removal properties. T...
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WO/2010/123465 |
The subject of the invention is a method for the treatment of biomedical implants for the improvement of antithrombogenic properties thereof. The mentioned biomedical implants are cardiovascular implants, especially artificial blood vess...
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WO/2010/123465 |
The subject of the invention is a method for the treatment of biomedical implants for the improvement of antithrombogenic properties thereof. The mentioned biomedical implants are cardiovascular implants, especially artificial blood vess...
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WO/2010/118335 |
Methods for protecting biomaterĪals comprise attaching CD47 or Ig domain thereof to the surface of the biomaterial, thereby inhibiting or reducing immune cell attachment and/or immune cell-mediated damage to the biomaterial. Also provid...
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WO/2010/113632 |
Disclosed is a surface-treating agent characterized by comprising a copolymer composed of, as monomer components, a monomer (A) having a hydrophilic functional group and represented by formula (1) or (2),a monomer (B) having a basic func...
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WO/2010/101722 |
A polymer comprising a phosphoryl choline moiety(ies), a composition comprising the polymer and optionally a bioactive agent, an implantable device such as a DES or a non-implantable device such as an angioplasty balloon comprising there...
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WO/2010/090097 |
Disclosed is an antibacterial catheter (1) which is characterized by comprising a tube-shaped main body (2) composed of a polymer material containing an antibacterial agent (3), wherein the antibacterial agent (3) is localized in the vic...
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WO/2010/057142 |
The present invention provides compositions and methods for the production of silk fibroin matrices surface-PEGylated on one or more surfaces. Such surface-PEGylated silk fibroin matrices can be used in biomedical applications, such as a...
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WO/2010/057142 |
The present invention provides compositions and methods for the production of silk fibroin matrices surface-PEGylated on one or more surfaces. Such surface-PEGylated silk fibroin matrices can be used in biomedical applications, such as a...
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WO/2010/026782 |
Previously reported composite materials each of which is composed of a hydrophilic high-molecular-weight matrix and a low-molecular-weight organic compound have such a problem that it is difficult to compound a low-molecular-weight organ...
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WO/2010/009335 |
Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable ...
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WO/2009/119761 |
Provided is a surface showing excellent antithrombotic properties. Also provided is a medical device having the same. An antithrombotic surface comprising polymer layers which are in different charged states and alternately layered, char...
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WO/2009/120968 |
The presently disclosed subject matter provides compositions comprising a first substrate-binding domain (a peptide or a polymer) having binding affinity for a tissue or a medical device, a second substrate-binding domain having binding ...
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WO/2009/110858 |
The present invention is directed to medical devices in which flow is channeled of blood and blood products for the purpose of effecting a chemical exchange to remove desired chemicals from the blood or blood products, and to impart nitr...
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WO/2009/110858 |
The present invention is directed to medical devices in which flow is channeled of blood and blood products for the purpose of effecting a chemical exchange to remove desired chemicals from the blood or blood products, and to impart nitr...
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WO/2009/089364 |
An optical fiber tip comprises a core and a recess formed in said core at a distal end of the optical fiber tip, said recess having a vertex within said core.
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WO/2009/089364 |
An optical fiber tip comprises a core and a recess formed in said core at a distal end of the optical fiber tip, said recess having a vertex within said core.
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WO/2009/081870 |
Disclosed is a medical device having excellent anti-thrombotic properties, excellent sliding properties, and an inhibitory effect on cell adhesion. The medical device comprises: a base on which a hydroxy group can be formed; and a biocom...
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WO/2009/065087 |
An automated apparatus and method for coating medical devices such as an intravascular stent, are disclosed in the method, a 2-D image of a stent is processed to determine (1 ) paths along the stent skeletal elements by which a stent sec...
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WO/2009/064372 |
The present invention relates to immobilized biologically active entities having heparin cofactor Il binding activity.
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WO/2009/064372 |
The present invention relates to immobilized biologically active entities having heparin cofactor Il binding activity.
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WO/2009/058146 |
The present invention is directed to medical devices including blood storage and handling products that comprise a specific polyphosphazene and the capability of releasing nitric oxide or other smooth muscle relaxant compounds in vivo or...
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WO/2009/049426 |
The invention features the use of a matrix consisting of low molecular weight components for use as a self-eliminating coating for implantable medical devices. The matrix coatings can be used to enhance biocompatibility and to control th...
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WO/2009/048314 |
The present invention provides implantable receptacle devices (and methods) for use in bone and tissue regeneration which provide immediate structural stability and strength to a zone where tissue regeneration is required. By virtue of t...
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WO/2009/045454 |
Implantable catheters treated with gentian violet and methods for disinfecting the catheters with alcohol are provided.
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WO/2009/035457 |
A dip coating apparatus and method of dip coating. The apparatus includes a guide surface, a bendable tube, a carriage, and a support assembly. The bendable tube redirectionally engages the guide surface intermediate the first and second...
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WO/2009/018325 |
A method, a kit, and an apparatus provide a coating on an implantable medical device. The apparatus includes housing, a sealed reservoir chamber disposed in the housing, a reducing template, and a reservoir access port. The sealed reserv...
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WO/2009/007046 |
The present invention relates to a vascular prosthesis with a porous wall made of synthetic material, wherein the wall is impregnated with microparticles on the surfaces of which blood coagulation inhibitors are immobilized.
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WO/2009/005258 |
Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed b...
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WO/2009/005258 |
Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed b...
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