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WO/2013/049827 |
An apparatus for providing at least one treatment to at least one tissue having a first structural arrangement configured to expand a first portion at a distal end of the apparatus, a second structural arrangement configured to expand a ...
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WO/2013/029024 |
A brachytherapy device includes a bioabsorbable support and a plurality of microcapsules on the support. Each of the plurality of the microcapsules includes a plurality of microspheres and a bioabsorbable microcapsule wall that encloses ...
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WO/2013/022797 |
Compounds according to Formula I and Formula II are potent inhibitors of PSMA activity: The invention also provides pharmaceutical compositions of a complex of a radionuclide and a Formula I compound or a Formula II compound and methods ...
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WO/2013/019975 |
The invention provides compositions and methods to treat cancer with an agent that increases reactive oxygen species (ROS) levels in cancer cell mitochondria ("an XTPP agent") or a pharmaceutically acceptable salt thereof, an inhibitor o...
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WO/2013/006556 |
A shielding device includes two elongated, parallel tubes joined at a distal portion, and a shield at least one of removably and slidably situated at the distal portion. An assembly includes an applicator configured for a treatment site,...
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WO/2012/178173 |
Extracellular-targeted drug conjugates (EDC) in which a targeting moiety targeting a protein associated with the Na,K-ATPase is linked to a drug that interacts with the Na,K-ATPase through a linker a stable linker are useful in the treat...
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WO/2012/174557 |
Inhalable pharmaceutical compositions can include an aqueous dispersion of particles including a hydrophobic bioactive agent (e.g., CoQIO) suitable for continuous aerosolization. Due to their chemical composition and methods of manufactu...
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WO/2012/149417 |
A device and method for retaining a position of a treatment applicator are described. The device includes a perineal retainer body configured to receive the applicator, the perineal retainer body configured to form a positive stop with a...
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WO/2012/141387 |
The present invention relates to a device for manufacturing radiopharmaceuticals. The present device for manufacturing radiopharmaceuticals includes a first module unit which obtains synthetic products through a reaction caused by mixing...
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WO/2012/138749 |
The invention relates to charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of using the same to reduce ocular toxicity as...
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WO/2012/112699 |
Systems and methods for delivering and infusing formulations containing riboflavin or its analogues, or other ophthalmic formulations, into corneal tissue are disclosed. Systems and methods are further disclosed to cross-link the corneal...
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WO/2012/112699 |
Systems and methods for delivering and infusing formulations containing riboflavin or its analogues, or other ophthalmic formulations, into corneal tissue are disclosed. Systems and methods are further disclosed to cross-link the corneal...
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WO/2012/112317 |
A method of treating a tumor in a subject, or reducing or preventing metastasis of a tumor in a subject, is provided comprising administering to the subject an amount of a bacteria labelled with, or comprising, one or more radionuclides ...
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WO/2012/091757 |
Arginase enzyme inhibitors are disclosed for treating or diagnosing conditions characterized either by abnormally high arginase activity or abnormally low nitric oxide levels in a mammal, comprising administering compositions of the inve...
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WO/2012/061348 |
A brachytherapy device includes a sealed housing having a radioactive material therein, and at least one shielding member extending away from the housing and configured to provide radiation shielding on at least one side of the housing.
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WO/2012/061348 |
A brachytherapy device includes a sealed housing having a radioactive material therein, and at least one shielding member extending away from the housing and configured to provide radiation shielding on at least one side of the housing.
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WO/2012/034157 |
A system, method and device for brachytherapy treatment verification is described herein. The verification may be in real time and may provide verification of one or more of dose, source position, dwell time and source activity. In one e...
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WO/2012/031282 |
Provided herein are silk fibroin-based photothermal elements and uses thereof. The silk fibroin-based photothermal elements comprise a plurality of plasmonic nanoparticle distributed in a silk fibroin matrix, and can generate heat when t...
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WO/2012/031282 |
Provided herein are silk fibroin-based photothermal elements and uses thereof. The silk fibroin-based photothermal elements comprise a plurality of plasmonic nanoparticle distributed in a silk fibroin matrix, and can generate heat when t...
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WO/2012/024085 |
Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand.
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WO/2012/024085 |
Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand.
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WO/2012/012282 |
This invention relates to synthetic bifunctional compounds comprising a first rho-associated kinase (ROCK) inhibiting compound and a second pharmaceutically active compound with complementary activity; the first and the second compounds ...
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WO/2012/003130 |
A system for delivering a treatment agent such as a radioactive source 26 to a targeted treatment site within a patient's body is disclosed. Aspects of the device provided herein include a cable 42 with contiguous sections 44 and 46 havi...
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WO/2012/003130 |
A system for delivering a treatment agent such as a radioactive source 26 to a targeted treatment site within a patient's body is disclosed. Aspects of the device provided herein include a cable 42 with contiguous sections 44 and 46 havi...
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WO/2012/003073 |
Provided herein are methods of treating neuropsychiatric disorders or improving the symptoms associated therewith administering a medical food, such as L-methylfolate, to a subject having the disorder. The neuropsychiatric disorder may b...
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WO/2012/000134 |
A composite type radioactive isotope sealed seed source is provided in present invention. Said sealed seed source comprises a core; a radioactive isotope layer which is deposited on the surface of the said core and contains radioactive i...
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WO/2011/153519 |
A system and method for monitoring progress of a radiopharmaceutical injection procedure includes: measuring and monitoring radiopharmaceutical activity of a radiopharmaceutical remaining in at least a portion of a disposable administrat...
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WO/2011/137497 |
Disclosed are an animal stunning apparatus and method for inducing rapid unconsciousness and insensibility. The apparatus includes a stunning station (10) in which a live subject animal is located in a confined position and an applicator...
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WO/2011/137497 |
Disclosed are an animal stunning apparatus and method for inducing rapid unconsciousness and insensibility. The apparatus includes a stunning station (10) in which a live subject animal is located in a confined position and an applicator...
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WO/2011/124780 |
The invention relates to a device (1) for preparing a syringe (S) equipped with a needle (7), said syringe (S) being housed in a sheath (F) for protection and gripping, said device being integrated in a metal-clad enclosure (3) provided ...
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WO/2011/116237 |
The present invention provides modified stem cells that comprise a delivery system that comprises at least one microparticle or nanoparticle, wherein the at least one microparticle or nanoparticle comprises an active agent. The present i...
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WO/2011/100586 |
Described here are brachytherapy applicators that comprise a modular support matrix. The modular support matrix may define the arrangement of radiation source lumens within the brachytherapy applicator. The modular support matrix can be ...
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WO/2011/053908 |
The present invention also features a brachytherapy system comprising a spiral cut tube having a first end and a second end; a radioactive brachytherapy source (RBS) disposed on the first end of the spiral cut tube; and a handle and a ge...
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WO/2011/043816 |
Tracers targeting phosphodiesterase1 for use in gamma radiation detection-based diagnostic techniques, particularly gamma-emitter labeled tracers for SPECT and positron emitter-labeled compositions for PET are disclosed. Radio-labeled mu...
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WO/2011/037615 |
A microfluidic radiopharmaceutical production system and process for synthesizing per run approximately one (1) to four (4) unit dose of a radiopharmaceutical biomarker for use in positron emission tomography (PET). The system includes a...
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WO/2011/017583 |
The present invention features compositions and methods for treating cancers such as melanoma, which have a subpopulation of self -renewing JARIDIB-positive cells essential to maintenance and metastatic progression of the cancer.
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WO/2011/011731 |
Systems and methods are provided for treating cervical and/or uterine cancers in brachytherapy with an intracavitary brachytherapy applicator. The system comprises a tandem adapted for insertion into a cervix of a patient. An ovoid assem...
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WO/2011/011731 |
Systems and methods are provided for treating cervical and/or uterine cancers in brachytherapy with an intracavitary brachytherapy applicator. The system comprises a tandem adapted for insertion into a cervix of a patient. An ovoid assem...
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WO/2010/151429 |
A vaginal cervical retractor used to maneuver and visualize the uterus during various medical examinations and procedures would include an inner tube provided with a movable assembly of plastic cups (cervical cup and vaginal cup) designe...
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WO/2010/151429 |
A vaginal cervical retractor used to maneuver and visualize the uterus during various medical examinations and procedures would include an inner tube provided with a movable assembly of plastic cups (cervical cup and vaginal cup) designe...
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WO/2010/132428 |
The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds. A preferred compound of the present invention has the following struc...
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WO/2010/101721 |
A rough, bio-absorbable strand is provided. More specifically, a bio-absorbable strand having a central body and a rough or irregular outer surface capable of securing the placement of the strand inside a patient is provided. The strand ...
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WO/2010/099126 |
A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling...
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WO/2010/099126 |
A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling...
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WO/2010/078370 |
The present invention relates to methods of synthesizing 18F-radiolabeled styrylpyridine and its tosylate precursor. The present invention further relates to stable pharmaceutical compositions comprising 18F-radiolabeled styrylpyridine.
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WO/2010/059563 |
Disclosed herein are systems and methods related to aneurysm treatment. More specifically, the systems and methods disclosed herein relate to localized treatment of aneurysms utilizing polymeric micelles that release therapeutic agent(s)...
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WO/2010/059563 |
Disclosed herein are systems and methods related to aneurysm treatment. More specifically, the systems and methods disclosed herein relate to localized treatment of aneurysms utilizing polymeric micelles that release therapeutic agent(s)...
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WO/2010/042793 |
Brachytherapy apparatus and methods for performing brachytherapy employing expandable members with at least one external fixation element, offering precise therapy due to rotational and/or longitudinal stability of the expandable member.
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WO/2010/025396 |
A brachytherapy multiple needle loading device and method are provided. The device allows multiple implantation devices to be loaded at the same time and has a gating retention mechanism that allows the user to load sources into implanta...
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WO/2010/009186 |
The present invention features liposomal formulations composed of at least one hydrophilic pharmaceutical compound loaded in the aqueous core of the liposome and at least one hydrophobic pharmaceutical compound in the bilayer of the lipo...
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