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Matches 1 - 50 out of 84,745

Document Document Title
WO/2018/109461A1
Provided are compositions comprising a bacterial strain of the genus Blautia, for use in a method of increasing the microbiota diversity and/or inducing stability of the microbiota of a subject.  
WO/2018/109520A1
The present invention relates to a composition comprising a given Lactobacillus rhamnosus strain and a given Lactobacillus paracasei strain wherein the ratio of said given Lactobacillus rhamnosus strain to said given Lactobacillus paraca...  
WO/2018/109525A1
The present invention discloses new anti-angiogenic extracellular vesicles (extracellular vesicles, EV) formed from stem/stromal mesenchymal cells (also known as mesenchymal stem cells, MSC), said EVs for the treatment of diseases charac...  
WO/2018/111321A1
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-12/IL-23 inhibitor. An embodiment of the disclosure relates to releasing the IL-12/IL-13 inhibitor at a location in the gast...  
WO/2018/111795A2
The present disclosure relates to methods, uses, pharmaceutical compositions comprising an sGC stimulator or a pharmaceutically acceptable salt thereof, alone or in combination with one or more additional therapeutic agents, for the trea...  
WO/2018/107696A1
A method for preventing and treating liver fibrosis, comprising administering an effective amount of plasminogen to a subject.  
WO/2018/110683A1
The present invention provides a technical means (preferably an easy-to-use means) for producing a tablet in which properties of an esomeprazole salt, such as chemical stability, are improved. Provided is an uncoated tablet in which the ...  
WO/2018/107364A1
Provided are applications of Collinsella shenzhenensis in treating and/or preventing inflammation-related diseases and cardiovascular diseases. Also provided are a composition used for treating and/or preventing the inflammation-related ...  
WO/2018/109730A1
The present invention relates to the use of probiotics to control the inflammatory process of the colon in subjects with structural modifications of the colon wall, preferably in subjects with diverticulosis, and affected by diverticular...  
WO/2018/109700A1
The present invention discloses new aiiti-angiogenic extracellular vesicles (extracellular vesicles, EV) formed from stent/stromal mesenchymal cells (also known as mesenchymal stem cells, MSC), said EVs for the treatment of diseases char...  
WO/2018/107698A1
A method for preventing and treating tissue and organ fibrosis, comprising administering an effective amount of plasminogen to a subject.  
WO/2018/109672A1
A pet food composition specifically formulated for a small dog can include a combination of specific antioxidants, amino acids, metabolism components, and bone health components to maintain health. Methods of maintaining health and modul...  
WO/2018/112194A1
Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at leas...  
WO/2018/107688A1
A method for preventing and/or treating fatty liver and related diseases thereof of a subject, comprising administering an effective amount of plasminogen to a subject. In addition, the present invention also relates to a medicine, pharm...  
WO/2018/109646A1
The present invention relates to a compound which is (R)-3-(1,4- dimethyl-1 H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-2-ethyl-2,3- dihydropyrido[2,3-f][l,4]oxazepin-4(5H)-yl)methyl)-4-methylp henyl) propanoic acid (I), or a pharmaceutica...  
WO/2018/111329A1
This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-1 inhibitor. An embodiment of the disclosure relates to releasing the IL- 1 inhibitor at a location in the gastrointestinal ...  
WO/2018/109647A1
The present invention relates to bisaryl amide analogs, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to bisaryl heterocycles of Formula (I).  
WO/2018/110686A1
The present invention provides a pharmaceutical composition for healing tissue, said pharmaceutical composition containing: adherent cells originating from mesenchymal tissue that has been treated with a physiologically active polypeptid...  
WO/2018/108084A1
Provided is a compound containing a tricyclic heteroaryl group. Specifically, provided are a compound (the definitions of groups are as stated in the description) having a structure as shown in formula (I), a pharmaceutical composition c...  
WO/2018/109693A1
The present invention relates to an orally administered pharmaceutical composition comprising a fixed-dose combination of simeticone in high-concentration microgranules and lansoprazole or the enantiomer thereof (dexlansoprazole) in ente...  
WO/2018/107693A1
A method for preventing and treating systemic sclerosis, comprising administering an effective amount of plasminogen to a subject.  
WO/2018/103729A1
Use of chlorogenic acid in preparation of drugs or health-care products for stimulating appetite. A pharmacological experiment indicates that chlorogenic acid can significantly increase the food intake of an anorexia rat, and the weight ...  
WO/2018/102854A1
Methods for controlling body weight and/or appetite in a subject are disclosed. In some embodiments, the methods involve administering to an overweight or obese subject an effective amount of a first agent comprising MIC-1, a MIC- 1 agon...  
WO/2018/104538A1
The present invention relates to an RNA suitable for treatment or prophylaxis of liver diseases. In particular, the present invention provides an RNA encoding at least one peptide or protein selected from the group consisting of an extra...  
WO/2018/103766A1
Disclosed is a compound as shown in formula I. Also disclosed are a synthesis method for the compound, and uses of the compound in the preparation of anti-cancer and anti-inflammatory drugs and a drug which treats hepatitis C.  
WO/2018/106845A1
Compositions of glycan polymers and methods of making and manufacturing the same are described herein. Also provided are methods of treating a disease or disorder with a glycan polymer preparation.  
WO/2018/106982A1
The present invention provides compositions and methods for enhancing beta cell maturation, health and function. The invention may be used for increasing insulin secretion in a cell, promoting the formation of cell clusters, or reducing ...  
WO/2018/104916A1
The present invention provides therapeutic compound for prevention and treatment of primary biliary cholangitis, (PBC). Specifically, the present invention provides pharmaceutical composition comprising a compound of Formula (I) or a pha...  
WO/2018/104499A1
Disclosed herein are methods for treating or limiting development of obesity or treating or limiting development of various fatty liver diseases by administering an inhibitor of apolipoprotein CIII.  
WO/2018/103624A1
The present invention relates to the use of a κ opioid receptor agonist in the preparation of a drug for treating pruritus caused by a farnesol X receptor agonist. The present invention also relates to the use of a farnesol X receptor a...  
WO/2018/105708A1
The present invention addresses the problem of developing a novel therapy for a chronic disease, against which conventional therapies show no or little efficacy, and provides a medicinal composition for treating and/or preventing an infl...  
WO/2018/100469A1
The present invention relates to a composition comprising hyaluronic acid, a natural molecule, and thickening agents. Said composition has been demonstrated to effectively counteract the discomfort caused by gastroesophageal reflux, prev...  
WO/2018/101425A1
The present invention provides a novel antibody targeting TLR9.  
WO/2018/100557A1
The present disclosure relates to a method of treating or preventing nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, a chronic granulomatous disorder, a polycystic ovary syndrome, a thyroid carcinoma, a thyroid autoimmune...  
WO/2018/100468A1
The present invention relates to a composition comprising at least one salt of alginic acid, hyaluronic acid, a natural molecule, and thickening agents. Said composition has been demonstrated to effectively counteract the discomfort caus...  
WO/2018/099493A1
Tropaeolum majus granules and a preparation method therefor. Said granules comprise in parts by weight: 10 to 20 parts of Tropaeolum majus, 3 to 8 parts of Glebionis coronaria, 3 to 5 parts of superfine powder of the stem and leaf of swe...  
WO/2018/100178A1
The invention provides a method for the production of a zeolite particle composition which has optimized characteristics, such as enhanced adsorption and specific ion exchange properties. A method and an apparatus for producing improved ...  
WO/2018/101481A1
[Problem] To provide a steroid-containing cell preparation exhibiting high therapeutic effects on diseases associated with cartilage tissue as a treatment target. [Solution] The present invention provides a prophylactic or therapeutic ag...  
WO/2018/102675A1
A method comprising administering an agent, for example a PCSK9 inhibitor, to a patient who suffers from fatty liver disease or is at risk of fatty liver disease, thereby reducing the risk of fatty liver disease, severity of fatty liver ...  
WO/2018/099363A1
Provided is the use of an insulin-like growth factor-2 for preparing a pharmaceutical composition, wherein the pharmaceutical composition is used for (i) promoting the expression of the macrophage PD-L1, and/or (ii) inhibiting the expres...  
WO/2018/101398A1
The present invention provides a pharmaceutical composition for use in the treatment or prevention of inflammatory bowel disease (IBD). More particularly, the present invention provides a pharmaceutical composition that contains apelin o...  
WO/2018/101329A1
The purpose of the present invention is to develop a therapeutic agent for inflammatory diseases such as inflammatory bowel disease and NASH, said therapeutic agent having few adverse effects and high efficacy. The present invention prov...  
WO/2018/100574A1
A method of reducing the liver toxicity of a liver-damaging agent is disclosed. The method comprises administering to the subject: (i) the liver-damaging agent; and (ii) an agent which alters the circadian rhythmicity of microbes of the ...  
WO/2018/101102A1
Provided are: a gastric inhibitory polypeptide elevation inhibitor that contains arabinoxylan as an active ingredient; and an agent for preventing or ameliorating stodgy feeling in the stomach.  
WO/2018/094974A1
A pharmaceutical composition for treating ischemic stroke and a preparation method and use thereof. The active pharmaceutical ingredients of the pharmaceutical composition include: 0.05-20 parts by weight of NADPH, and 10-100 parts by we...  
WO/2018/096497A1
The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, form...  
WO/2018/094972A1
A sugar-coated tablet of rice bran sterol, comprising: rice bran sterol, filler and a coating agent, the mass ratio of rice bran sterol, filler and coating agent being 1:3.9-4.5:1.30-1.35; in the filler, the mass ratio of starch, dextrin...  
WO/2018/096334A1
The present invention relates to compositions comprising: malt extract including a plurality of enzymatically active enzymes including at least fructanase and amylase; one or more medium-chain triglycerides (MCTs) and/or at least one bio...  
WO/2018/095378A1
Disclosed are a piperidine-2,6-diketone derivative, a pharmaceutical composition thereof, and the use thereof in the treatment for Crohn's disease.  
WO/2018/097308A1
The present invention pertains to: a ligand-binding molecule, the ligand binding activity of which is reduced by cleavage of a cleavage site thereof; a production method for the ligand-binding molecule; a complex formed of the ligand-bin...  

Matches 1 - 50 out of 84,745