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Matches 1 - 50 out of 83,147

Document Document Title
WO/2018/161507A1
A novel low-toxicity tripterygium glycoside, being obtained by chemical processing tripterygium glycoside and adding triptriolide. The novel low-toxicity tripterygium glycoside can effectively alleviate renal pathological damage and prot...  
WO/2018/164566A1
The invention relates to the simultaneous use of the two stereoisomeric forms of retinoic acid with or without the addition of an antibacterial agent effective against Propionibacterium acnes in a cosmetically acceptable topical formulat...  
WO/2018/162527A1
The invention relates to aqueous pharmaceutical compositions comprising the compound 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy }-N-(methylsulfonyl) acetamide; glycine; polysorbate 20; and an aqueous phosphate buffer, w...  
WO/2018/165647A1
The application pertains to methods of treating and/or preventing actinic keratosis, comprising administering a therapeutically effective amount of KX-01, (I), to a subject in need thereof.  
WO/2018/163119A1
The present description relates to 1-piperidinepropionic acid or pharmaceutically acceptable salts thereof, or pharmaceutical compositions comprising it, for use in the treatment of chronic fibrosing diseases.  
WO/2018/162577A1
The present invention relates to compositions, immunogenic or vaccine compositions and pharmaceutical compositions for the prevention or treatment of a condition or disorder selected from a pruritic condition or an allergic condition, of...  
WO/2018/162645A1
The invention provides a compound of formula (I) wherein: A, B, C, D, W, X, Y and Z are each independently selected from H and OH; or a salt thereof; for use in the treatment and/or prevention of a skin condition in a subject, wherein th...  
WO/2018/165189A1
A topical composition comprising a synthetic compound that is an ester of sinapinic acid, a method for treating skin to provide one or more benefits selected from (a) protecting against UV radiation, (b) inhibiting DNA damage in skin cel...  
WO/2018/159478A1
Provided is an external preparation composition containing: (A) anhydrous magnesium chloride; (B) a polymer having at least one from among a carboxyl group, a hydroxyl group, and an acetate group; (C) a water-soluble aluminum salt; and (...  
WO/2018/158741A1
The present disclosure relates to methods for modifying the psoriasis disease course in particular patients having chronic plaque-type psoriasis and inhibiting the progression to psoriatic arthritis (PsA) in these patients, using IL-17 a...  
WO/2018/159734A1
The present invention addresses the problem of providing a production method for crystals of 5-cyclopropyl-2-((1-(3-fluorobenzyl)-1H-indol-5-yl)amino)nic otinic acid. A compound represented by general formula [3] (wherein R1 represents a...  
WO/2018/157773A1
Provided are a repair peptide for use in promoting post-traumatic tissue repair and regeneration, and an application thereof. The repair peptide is a linear or cyclic peptide which is 4-15 amino acids in length and which contains four or...  
WO/2018/157975A1
According to the present invention there is provided a cosmetic composition comprising: (i) a polyphenolic antioxidant agent; and (ii) a sphingosine compound.  
WO/2018/160590A1
Disclosed are stable, non-irritating, retinoid containing formulations and delivery systems for topical application to the skin. The disclosed topical formulations and delivery systems provide controlled release of the retinoid to the sk...  
WO/2018/157730A1
The present invention relates to a urea-substituted aromatic ring-linked dioxane-quinazoline compound of formula (1) and a urea-substituted aromatic ring-linked dioxane-quinoline, or a pharmaceutically acceptable salt thereof or a hydrat...  
WO/2018/159650A1
The purpose of the present invention is to provide a compound which has a guanidine skeleton and inhibits the protease activity of MALT1 to exhibit a therapeutic effect or prophylactic effect on autoimmune diseases such as psoriasis. The...  
WO/2018/160613A1
The invention provides an econazole nitrate and thiourea medical patch for the treatment of nail and skin onychomycosis, achieving improved drug penetration, and thus allowing more drug to penetrate into the nail bed and reach the minimu...  
WO/2018/157244A1
Methods for using compositions comprising a Granzyme B inhibitor and a pharmaceutically acceptable carrier for treating and/or preventing blistering and/or peeling of a skin of a subject are provided. Also provided are methods for using ...  
WO/2018/160926A1
The present disclosure provides methods for the treatment of a lesion, such as a cancerous lesion, a precancerous lesion, or a benign lesion (e.g. a benign lesion on the skin) in a subject comprising administering to the subject a therap...  
WO/2018/160158A1
The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of t...  
WO/2018/155660A1
Provided is a novel use of dead cell bodies of a lactic acid bacterium. A novel use of dead cell bodies of a lactic acid bacterium can be discovered by selecting an optimal lactic acid bacterium and selecting an optimal additive.  
WO/2018/156180A1
Provided are various embodiments relating to anti-IL31 antibodies binding to canine IL31. Such antibodies can be used in methods to treat IL31-induced conditions in companion animals, such as canines, felines, and equines.  
WO/2018/152614A1
A method of reducing, preventing or treating concussion, acne or neuropathy, comprising having a patient in need thereof sleep in proximity to or in contact with an article containing copper. An article having anti-concussion, -acne or -...  
WO/2018/156552A1
Glitazone compounds, such as pioglitazone, are useful for topical treatment of dermatologic conditions, such as keratosis pilaris, that are associated with a decrease in number or function of sebocytes.  
WO/2018/156051A1
The invention relates to novel polymer-based antiseptic compositions for treating wounds and/or for use in surgical operations, which form a film on the wound surface and have antiseptic, anesthetic and antitoxic effects. The composit...  
WO/2018/156052A1
The invention relates to novel colloidal antiseptic compositions for treating wounds and/or for use in surgical operations, said compositions forming an elastic air- and water-permeable biodegradable film on the wound surface and having ...  
WO/2018/157011A1
Disclosed are methods for treating burn wounds utilizing a debridement agent and a viable genetically-modified xenogeneic skin substitute, and combination products utilizing those treatment agents.  
WO/2018/153235A1
A glaucocalyxin A derivative, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition thereof and uses thereof in the preparation of drugs for treating psoriasis.  
WO/2018/148795A1
A topical pharmaceutical composition comprising a solution of 2-(2-ethoxyethoxy)ethanol in a first solvent that is a 2-(2-ethoxyethoxy)ethanol solvent.  
WO/2018/151832A1
Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprise...  
WO/2018/151239A1
The present invention addresses the problem of providing an acid-sensing ion channel inhibitor which is orally administrable. The solution of the present invention is a compound represented by formula (I) or a pharmaceutically acceptable...  
WO/2018/148785A1
A pharmaceutical composition comprising a cannabinoid and a siloxane wherein the cannabinoid is dissolved in the composition.  
WO/2018/148787A1
A pharmaceutical composition comprising a cannabinoid and a siloxane wherein cannabinoid is dissolved in the composition.  
WO/2018/150429A1
A liposome for use in delivering a therapeutically active agent to a subject in need thereof is disclosed herein. The liposome comprises: a) at least one bilayer-forming lipid; b) a polymeric compound having the general formula I: (I) wh...  
WO/2018/151834A1
The present invention relates to, inter alia, methods of treatment and combinations of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3, 4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid (Compound 1) useful for the treatment of ...  
WO/2018/150309A1
The present invention relates to a new composition for use in the treatment of cough comprising one or more polysaccharide fractions of plantain, one or more polysaccharide fractions of marshmallow, honey, brown sugar, one or more polyph...  
WO/2018/151054A1
This oily composition contains: 70-100% by mass of an oily composition (A) which is mainly composed of a steradiene having a 3, 5-conjugated diene structure converted from a phytosterol by means of dehydration of a hydroxyl group in the ...  
WO/2018/151815A1
Provided herein are improved processes for the preparation of a compound of Formula IX (AG- 10). Also provided herein are pharmaceutically acceptable salts of Formula (I) and Formula (lb) as well as crystalline types of Formula IX (AG- 1...  
WO/2018/148786A1
A pharmaceutical composition comprising a cannabinoid and a siloxane wherein cannabinoid is dissolved in the composition.  
WO/2018/150429A9
A liposome for use in delivering a therapeutically active agent to a subject in need thereof is disclosed herein. The liposome comprises: a) at least one bilayer-forming lipid; b) a polymeric compound having the general formula I: (I) wh...  
WO/2018/149991A1
The present invention relates to particular sulfonamide derivatives, the pharmaceutically acceptable addition salts thereof, the hydrates thereof and/or the solvates thereof, and also the use thereof as inverse agonists of retinoid-relat...  
WO/2018/150265A1
Hidradenitis suppurativa can be treated by administering a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds interleukin-1α (IL-1α)....  
WO/2018/151285A1
Provided are a novel itching neurotransmitter and a therapeutic means for itchiness. A prophylactic or therapeutic drug for itching skin diseases, said drug comprising a cholecystokinin-2 receptor antagonist as an active ingredient.  
WO/2018/146354A1
The invention relates to an emulsion containing a mixture of aqueous and oily phases, in which the aqueous phase comprises seawater, a viscosity agent and a wetting agent, and in which the oily phase comprises polyglyceryl, hectorite, pr...  
WO/2018/145712A1
The present invention relates to a composition comprising 3-(4- hydroxyphenyl)propanoic acid amide (PA) and whey protein. In further aspects, the invention relates to food ingredients and food products comprising said composition and use...  
WO/2018/146504A1
The effect of the leaves water extract of lagenaria siceraria (sweet variety) on wound healing and diabetic wound healing in Wistar albino rats was determined in comparison with Fucidin ointment 2% and Solcoseryl ointment 10% (reference ...  
WO/2018/146171A1
The present invention relates to the treatment of mast cell activation diseases (MCAD). The present invention is based on the discovery that aminoquinoline compound (such) can improve clinical symptoms present in several MCAD patients. I...  
WO/2018/147768A1
The invention relates to the pharmaceutical industry, and specifically to a medicinal preparation in the form of a fast-dissolving biocompatible film for transbuccal use that includes a therapeutically effective quantity of a pharmacolog...  
WO/2018/145147A1
The present invention relates to a method of treating a fibrotic disease condition characterized by excessive collagen formation in a subject including a human. The fibrotic disease includes fascial fibromatosis and a keloid scar. The me...  
WO/2018/148638A1
Disclosed herein, in part, are pharmaceutical compositions comprising a MetAp-2 inhibitor and a pharmaceutically acceptable excipient. The pharmaceutical compositions are contemplated to be useful, for example in the treatment of obesity.  

Matches 1 - 50 out of 83,147