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Matches 1 - 50 out of 83,932

Document Document Title
WO/2018/225728A1
Provided is a glycosaminoglycan-producing promoter containing, as an active ingredient, an inositol derivative in which sugar binds to inositol. Also provided is a composition for promoting glycosaminoglycan production, the composition c...  
WO/2018/227146A1
The present disclosure provides a composition comprising a first amount of a Vitamin D compound and a second amount of a probiotic compound. The disclosure also provides a method of treating an atopic condition in a subject in need there...  
WO/2018/225673A1
Disclosed are: a method for manufacturing a therapeutic composition containing mammalian cells, said method comprising dispersing the mammalian cells in an aqueous glucose solution having a concentration of about 3-10% or Ringer's acetat...  
WO/2018/224995A1
The present invention relates to a topical combination and topical compositions comprising lactobacilli and metal and/or semimetal oxides, useful in the prophylaxis and/or treatment of cutaneous and mucosal diseases, as well as their use...  
WO/2018/225718A1
Provided is an agent for inhibiting skin trouble caused by a microparticulate substance, the agent containing, as an active ingredient, an inositol derivative in which sugar binds to inositol. Also provided is a composition for inhibitin...  
WO/2018/224614A1
The present invention relates to the use of a VEGF inhibitor for use for preventing and/or treating acne.  
WO/2018/225006A1
The present invention relates to the use of a formulation for oral use comprising ozonated oil in the prevention and/or treatment by oral administration of systemic tissue diseases caused by monocyte inflammation, more in particular skin...  
WO/2018/224615A1
The present invention relates to a method for treating hyperpigmentary skin disorder. By using normal human melanocytes (NHMs) and normal human keratinocytes (NHKs), which are infected with CLEC12B siRNA/shRNA/RNAi lentiviral particles, ...  
WO/2018/223830A1
Provided is a preparation method of a freeze-dried human mesenchymal stem cell exosome powder, comprising the steps of: 1) culturing, purification and passaging of human mesenchymal stem cells; 2) inducing large-scale synthesis of the hu...  
WO/2018/220442A2
Provided herein are stromal stem cell therapeutics and methods of use in treating disease.  
WO/2018/218521A1
Disclosed herein are compositions and methods for the treatment of conditions induced by chronic inflammation. According to some embodiments, the compositions and methods involve the use of metformin and sodium butyrate in the treatment ...  
WO/2018/220916A1
Provided is a composition that exhibits the following: an excellent permeability into the skin by amino acids, derivatives thereof, and active ingredients; no timewise change in odor and performance; low irritancy; and an excellent tacti...  
WO/2018/219109A1
Disclosed is a drug for preventing and treating alopecia, wherein same comprises the following active ingredients: compositions having more than one flavonoid compound that reduces capillary permeability, calcium and vitamin C. The drug ...  
WO/2018/221713A1
The purpose of the present invention is to solubilize a sparingly-soluble component in a solution, to provide a sparingly-soluble component-containing solution, to increase the solubility of a sparingly-soluble component in water (for ex...  
WO/2018/220253A1
The present invention relates to novel carboxylic acid derivatives of 11-oxo-11H-pyrido [2,1-b]quinazoline-6-carboxamide as potent inhibitors of protein kinase, to pharmaceutical compositions containing them and to the use of said compou...  
WO/2018/221534A1
The oily humectant comprises component A, which is ditrimethylolpropane, and component B, which is an esterified product of one or more fatty acids selected from C6-12 saturated fatty acids, or comprises component A, component B, and com...  
WO/2018/221521A1
The present invention provides an anti-IGF-I receptor antibody that binds specifically to an IGF-I receptor of a vertebrate and has the proliferation-inducing activity of a vertebrate-derived cell, or a fragment thereof, or derivatives o...  
WO/2018/221547A1
The present invention provides a moisturizing topical preparation containing as an active ingredient at least one selected from pentosan polysulfate and pharmaceutically acceptable salts thereof as well as solvates of these pharmaceutica...  
WO/2018/221543A1
The present invention provides: an I-type crystal of (E)-2-(7-trifluoromethyl chromane-4-ylidene)-N-((7R)-7-hydroxy-5,6,7,8-tetrahydronaph thalene-1-yl)acetamide having an excellent TRPV1 antagonistic activity; a medication and a medicat...  
WO/2018/221679A1
This 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative or a salt thereof has BRD4 inhibitory activity and is therefore useful as a drug, especially as an agent to prevent and/or treat diseases involving BRD4.  
WO/2018/221562A1
According to the present invention, it is found that dopamine D2-like receptor agonists acts on a dopamine D2-like receptor in an activated Th cell and thereby inhibits the production of Interleukin-8 (IL-8).  
WO/2018/220252A1
The present invention relates to novel 11-oxo-11H-pyrido[2,1 b]quinazoline-6-carboxamide derivatives of formula (I) as potent inhibitors of protein kinase, to pharmaceutical compositions containing them and to the use of said compounds f...  
WO/2018/220544A1
The use of xibornol as an active agent in the treatment of acne vulgaris is disclosed, said xibornol having shown a remarkable bacteriostatic and bactericidal action on the bacterium mainly responsible of the onset and worsening of acne ...  
WO/2018/215818A1
The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and...  
WO/2018/216659A1
[Problem] The purpose of the present invention is to provide an emulsion composition which contains glycyrrhetinic acid, glycyrrhizic acid and derivatives and/or salts thereof, and ufenamate, and is prevented from the formation of precip...  
WO/2018/213882A1
The present invention relates extracts from physiologically stressed Arthrospira having anti-inflammatory activity and/or the ability to stimulate growth of new cells, compositions comprising the extracts having anti-inflammatory activit...  
WO/2018/216666A1
The present invention relates to an ultraviolet light reflecting agent composition or a water repellent agent composition, which contains at least one compound selected from among 2-pentacosanone, 2-heptacosanone, 2-nonacosanone, tetraco...  
WO/2018/213934A1
The present disclosure relates to bioactive self-assembling peptides, nanofibers and hydrogels for activating human mast cells. The peptides, nanofibers and hydrogels comprise a self-assembling peptide that mediates self-assembly linked ...  
WO/2018/216744A1
The present invention addresses the problem of providing a cosmetic and a skin protecting agent by which the balance of skin indigenous bacteria can be improved and, preferably, the ratio of Staphylococcus epidermidis, which is a useful ...  
WO/2018/210969A1
The subject of the present invention is a synthetic polysulfated oligosaccharide having 1 to 4 monosaccharide units, salts thereof, and complexes thereof, for use thereof for treating diabetic foot ulcer in arteriopathic patients.  
WO/2018/212147A1
Provided is a novel agent containing a vegetable-derived component, which has an effect against the dullness of the skin and an effect against the deterioration of a skin barrier function. A skin dullness eliminating agent or a skin barr...  
WO/2018/211325A1
The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and methods of using same to treat a variety of conditions and disorders.  
WO/2018/211297A1
Dermatological formulations for cosmetic and pharmacological use comprising, in combination with one another, 5-hydroxy-N-acetyltryptamine or N- Acetylserotonin (NAS) and melatonin or 5-methoxy-N-acetyltryptamine (MLT). The formulations ...  
WO/2018/212341A1
The present invention addresses the problem of providing an active ingredient having an effect of preventing, ameliorating or treating an acanthotic disease and/or an acanthotic symptom. This problem is solved by an agent for preventing,...  
WO/2018/210207A1
A compound as represented by formula (I), and optical isomers, solvates, pharmaceutically-acceptable salts, or prodrugs thereof. The present invention has urate transporter 1 (URAT1) inhibitory activity, can be used for treatment of gout...  
WO/2018/206742A1
The present invention relates to TRPV1 modulator compounds of formula (I) or their pharmaceutically, veterinary or cosmetically acceptable salts, or their stereoisomers or mixtures thereof, wherein m is an integer selected from 1 to 3; R...  
WO/2018/207952A1
A composition for hair growth and/or hair restoration, which contains a compound represented by formula I. (In formula I, one of R1 and R3 represents a hydrogen atom or a hydroxyl group, and the other one represents a group represented b...  
WO/2018/206409A1
Disclosed is a substance which down-regulates the activity of a MAST gene, or the activity of a transcription or translation product of a MAST gene, for use in the prevent and/or treatment of an inflammatory skin condition in a mammalian...  
WO/2018/209262A1
Topical pharmaceutical compositions and methods for treating a skin disease include tazarotene or a pharmaceutically acceptable salt of tazarotenic acid and an oil-in-water emulsion vehicle.  
WO/2018/207882A1
Provided are compounds that can have an inhibitory action on BET family proteins and are expected to be useful as agents for the prevention or treatment of, for example, autoimmune diseases and/or inflammatory diseases (for example, rheu...  
WO/2018/209358A3
A method of delivering a recombinant virus to a skin tissue is provided. The method includes applying ultrasound to the skin tissue, and administering the recombinant virus to the skin tissue.  
WO/2018/207812A1
The purpose of the present invention is to provide therapeutic agents for bedsore and skin wound and methods for treating bedsore and skin wound. The present invention provides a bedsore therapeutic agent or a bedsore treatment method or...  
WO/2018/206867A1
The present invention relates to the production of novel bactericides and antifungal agents.  
WO/2018/208173A1
Many people suffer from fungal infection of the skin, especially of the feet. The infection may manifest with peeling, redness, itching, burning, blisters and sores. It is known to use various oils for treatment however formulating them ...  
WO/2018/208369A1
Disclosed herein are therapeutic uses of polymer conjugates, including SNA-120 and SNA-125, comprising an active agent linked to a polymer, wherein the active agent comprises an indolocarbazole compound or derivative thereof. The disclos...  
WO/2018/207810A1
Provided are: a method for producing an extract or the like which contains a large amount of a component more useful for an anti-aging effect than a conventional placenta-derived raw material, wherein the extract or the like is produced ...  
WO/2018/204475A1
The invention provides a method of increasing blood flow or perfusion in an ischemic tissue; inducing angiogenesis, neovascularization or revascularization; increasing skeletal muscle viability; promoting ischemic skin wound healing; tre...  
WO/2018/203048A1
The invention relates to a silyl-containing polymer that is used, together with a tackifying resin to form an adhesive composition capable of storing and delivering drugs to the skin of a user. Typically the composition is formed into a ...  
WO/2018/201549A1
A skin care product for protecting the sebum membrane of a child, comprising in parts by weight: 10-35 parts of a milk extract, 30-55 parts of vegetable oil, 5-10 parts of ceramide, 10-16 parts of an aloe extract, and 6-10 parts of an oa...  
WO/2018/203762A1
The present invention relates to a new use of 2-[(3Z)-6- fluoro-2-methyl-3 - [(4-methylsulfinylpheny l)methylidene] inden- 1 - yl] acetic acid (sulindac) of the formula 1 to making of pharmaceutical preparations for the treatment of diff...  

Matches 1 - 50 out of 83,932