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Matches 101 - 150 out of 5,936

Document Document Title
WO/2013/141202
Provided are a method for treating muscle atrophy, and a method and means for promoting muscle hypertrophy. The present invention provides a muscle-building agent characterized by comprising a TRPV1 agonist as an active component; as wel...  
WO/2013/137832
The invention relates to myostatin inhibitors, and in particular, to myostatin inhibitors comprising small molecules, and pharmaceutical compositions comprising the myostatin inhibitors. The invention also relates to methods for treating...  
WO/2013/135928
The present invention relates to the use of obestatin, or to the nucleotide sequence that codes for same, as an in vitro myogenic agent, and for the production of a drug for muscle regeneration, preferably for musculoskeletal regeneratio...  
WO/2013/138662
The disclosure provides novel conjugates comprising antisense oligonucleotides that hybridize to a DMPK transcript and a 3E10 antibody or binding fragment thereof. Also considered are these conjugates further comprising MBNLl polypeptide...  
WO/2013/134660
The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds ...  
WO/2013/133325
[Problem] To provide a compound which has excellent serotonin 5-HT2C receptor activating activity. [Solution] A compound represented by formula (1) or a salt thereof. (In the formula, ring A represents an optionally substituted aromatic ...  
WO/2013/129443
Provided are: a novel compound having an excellent Aurora-A-selective inhibitory activity and useful as an anti-cancer agent that can be administered orally; a novel anti-tumor effect enhancer for a microtube agonist comprising a taxane-...  
WO/2013/129603
The present invention addresses the problem of developing and providing a method for designating a disease that relates to the amount of TDP-43 existing in cells and a method for producing a TDP-43 binding inhibitor. By collecting cells ...  
WO/2013/125674
[Problem] A main objective of the present invention is to provide a cell preparation useful for treatment of diseases in bone joints and repairing muscles which have been degenerated or damaged. [Solution] The present invention provides ...  
WO/2013/125634
 Provided are a TLR4 agent, a tissue homeostasis agent, a hepatocyte growth factor inducer, a tissue repairing agent, and a sirtuin inducer using hyaluronic acid fragments. Hyaluronic acid fragments selected from sizes of 2-20 sugar ...  
WO/2013/126919
Novel fusion proteins compromising nuclear factor kB essential modulator- binding (NEMO) domain or a fragment thereof and MCoTI-I/II or a fragment thereof, and their use for the treatment of inflammatory diseases and other medical condit...  
WO/2013/126521
Provided herein are methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and detrusor external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in an individual via the use of stably expr...  
WO/2013/122029
The purpose of the present invention is to provide an aromatic ring compound exhibiting GPR40 agonist activity. The compound represented by formula (I) (refer to the description for information pertaining to each symbol in the formula) o...  
WO/2013/122188
Provided is an agent, said agent having an improved effect of enhancing NO production, for preventing or ameliorating vascular endothelial malfunction and symptoms that occur with the progress of vascular endothelial malfunction such as ...  
WO/2013/118773
The purpose of the present invention is to provide a prophylactic or therapeutic agent for idiopathic inflammatory myopathies and idiopathic inflammatory myopathies in which steroid myopathy is induced during the treatment thereof. The p...  
WO/2013/118854
Provided is a drug for the treatment and/or prevention of pain or a drug for the treatment and/or prevention of sodium channel-mediated diseases. A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: Ar...  
WO/2013/114413
The present invention relates to a method for treating muscular dystrophy which comprises administering diethyl- [ 6- ( 4-hydroxycarbamoyl-phenyl-carbamoyloxy-methyl ) - naphthalen-2-yl-methyl ] -ammonium chloride or other pharmaceutical...  
WO/2013/113772
The invention relates to a medicament containing cimicifuga, extracts from cimicifuga, saponine-containing fractions of cimicifuga for use with muscle weakness and for prevention of muscle weakness, in particular sarcopenia and myocardia...  
WO/2013/113857
The invention relates to a pharmaceutical dosage form comprising (1r,4r)-6'-Fluoro-(N- methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro-[cyclohexane -1,1'-pyrano[3,4,b]- indol]-4-amine or a physiologically acceptable salt there...  
WO/2013/116691
The present invention relates to methods for improving muscle strength and treating muscular dystrophy.  
WO/2013/112053
The current invention provides animproved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.  
WO/2013/108926
The present invention provides a prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis, which contains an anacardic acid derivative, and a method of screening for a prophylactic and/or therapeutic drug for amyotrophic l...  
WO/2013/102904
Disclosed herein are AAV-based viral vectors encoding GNE from muscle-specific and non- muscle specific promoters, and the use of same in treating myopathies associated with altered GNE function.  
WO/2013/102265
Disclosed are polypeptides, compositions and methods for the treatment or prophylaxis of multiple sclerosis. The method involves the steps of administering a polypeptide, or nucleic acid encoding the polypeptide, comprising the GluR2 NTa...  
WO/2013/100190
The purpose of the invention is to provide a drug to produce highly efficient skipping of exons 55, 45, 50, and 44 of a human dystrophin gene. The invention provides an oligomer that makes it possible to skip exons 55, 45, 50, and 44 of ...  
WO/2013/101949
The present embodiments relate to topically delivered compounded medications. A transdermal cream may provide the effective topical administration of multiple medications simultaneously. The transdermal cream may include low concentratio...  
WO/2013/099982
A shikuwasa (Okinawa lime) extract, preferably an extract of a fruit or a leaf of shikuwasa with water and/or an organic solvent, a supercritical extract of a fruit or a leaf of shikuwasa or a subcritical extract of a fruit or a leaf of ...  
WO/2013/100566
A phenyl alkyl carbamate derivative compound and a pharmaceutical composition containing the compound are provided. More specifically, the phenyl alkyl carbamate derivative compound and a pharmaceutically acceptable salt thereof, a compo...  
WO/2013/100566
A phenyl alkyl carbamate derivative compound and a pharmaceutical composition containing the compound are provided. More specifically, the phenyl alkyl carbamate derivative compound and a pharmaceutically acceptable salt thereof, a compo...  
WO/2013/092269
The invention relates to pharmaceutical compositions comprising PPAR agonists and Nrf2 activators and methods of using combinations of PPAR agonists and Nrf2 activators for treating diseases such as psoriasis, asthma, multiple sclerosis,...  
WO/2013/088084
The invention relates to phytoecdysones for use in improving muscle quality in obese and/or sarcopenic mammals. More particularly, the invention relates to the obese mammals subjected to a low‑calorie diet. The phytoecdysones are advan...  
WO/2013/090205  
WO/2013/085016
General formula (I): The present invention pertains to: a pyridone derivate or a salt thereof represented by general formula (I); or a medicine containing the pyridone derivative or salt thereof as an active ingredient. [In the formula, ...  
WO/2013/082667
The invention provides a method for treating a condition in which growth hormone administration is beneficial, for treating osteoarthritis, for increasing chondrocyte, proteoglycan or collagen production or quality or repair or promoting...  
WO/2013/085017
General formula (I): The present invention pertains to: a pyridone derivate or a salt thereof represented by general formula (I); or a medicine containing the pyridone derivative or salt thereof as an active ingredient. [In the formula, ...  
WO/2013/085351
The present invention relates to a pharmaceutical composition comprising diaminodiphenylsulfone (dapsone, DDS) or the pharmaceutically acceptable salts thereof as active ingredients for preventing or treating diseases associated with mus...  
WO/2013/081094
The purpose of the present invention is to provide a compound that can act on mGluR5 selectively to inhibit the signaling of mGluR5. The present invention provides an imidazo[1,2-a]pyridine derivative typified by the compound shown below...  
WO/2013/079487
The present invention relates to an APJ receptor agonist or an apelinomimetic for the treatment or the prevention of a dysfunction associated with aging.  
WO/2013/081118
(Problem) To provide a novel compound having read-through activity, and a therapeutic agent for nonsense mutation diseases containing the compound. (Solution) A compound represented by the general formula (1), and a pharmaceutical compos...  
WO/2013/078261
The present invention provides methods for improving muscular function or treating a muscular disorder in an individual by administering to the individual a pharmacologically effective amount of a compound that inhibits microtubule-depen...  
WO/2013/074557
The present invention provides compositions and methods which involve specifically antagonizing GDFS and Activir) A. Sn certain embodftTtents, compositions are provided which comprise a GDF8-specifie binding protein and an Activin A-spec...  
WO/2013/074636
Agents, compositions, and medicaments that pertain to modulating the activity of muscle specific kinase receptor (MuSK) and methods and uses thereof to modulate MuSK activity are encompassed herein. Also encompassed are screening assays ...  
WO/2013/067591
The present disclosure relates generally to the field of pain management, including methods and formulations for the topical management of pain, such as localized pain. The present disclosure further teaches combination therapy to topica...  
WO/2013/067639
The present invention relates to uses and methods comprising one or more RANK/RANKL antagonists or of a pharmaceutical composition comprising one or more RANK/RANKL antagonists and a pharmaceutically acceptable carrier for treating neuro...  
WO/2013/064585
Compositions comprising mechanosensitive ion channel blockers, such as gadolinium, or N-cadherin antagonists or connexin 43 inhibitors enable musculoskeletal fibroproliferative disorders, such as Dupuytren's and other fibromatosis and li...  
WO/2013/063536
The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIB and uses for same.  
WO/2013/057230
The present invention relates to whey protein micelles for use in the treatment and/or prevention of a condition linked to a reduced concentration of plasma amino acids in a patient. A further aspect of the invention is a meal replacemen...  
WO/2013/058194
Provided are a pharmaceutical product, a quasi-pharmaceutical product, a food, an animal food, and a material mixable thereto that have an excellent SRF signal activation effect and are highly safe. This SRF signal activating agent compr...  
WO/2013/059606
Disclosed are methods of treating a muscle disease and improving normal muscle function by administering a therapeutically effective amount of an isoprenoid antibiotic. Also disclosed are methods of upregulating hnRNP L and hnRNP L targe...  
WO/2013/057231
The present invention relates to a non-therapeutic use of whey protein micelles to enhance muscle protein synthesis in a subject. Further aspects of the invention are food compositions comprising whey protein micelles to be administered ...  

Matches 101 - 150 out of 5,936