Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 651 - 700 out of 45,474

Document Document Title
WO/2013/128276
Disclosed is an immediate release solid oral dosage form comprising (i) an active agent; and (ii) a material that is sensitive to acidic pH;  
WO/2013/129931
The invention relates to a composition comprising: (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; and (ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), ...  
WO/2013/129413
[Problem] The objective of the present invention is, in a kit that is for preparing a carbon-dioxide-containing composition containing an oxygen-containing gel composition and a carbonate-containing gel composition, to provide a formulat...  
WO/2013/129220
The present invention provides a pharmaceutical, pharmaceutical composition, or food in which a dipeptide comprising Met (M) or an analog thereof and His (H) or an analog thereof is an active ingredient, as well as a method and use for p...  
WO/2013/129977
The invention relates to the field of the pharmaceutical industry and medicine. The problem of the invention consists in producing a pharmaceutical composition having neuroprotector, antiamnaesic, antioxidant, antihypoxic and antiischaem...  
WO/2013/128239
The invention relates to the use of an Engrailed protein as a medicament for increasing dopamine synthesis by dopaminergic neurons, in particular in the management of conditions associated with a decrease of dopamine levels without loss ...  
WO/2013/127728
The present invention relates to a hormone containing oil-in-water emulsion for parenteral administration comprising a) progestogen and/or estrogen and b) fish oil triglycerides, wherein the fish oil triglyceride consists of glycerol whi...  
WO/2013/130826
The present invention is based on the discovery of polyclonal IgG's ability to promote Schwann cell maturation, differentiation, and myelin production. Methods for treating non-idiopathic, demyelinating peripheral neuropathies in mammals...  
WO/2013/129443
Provided are: a novel compound having an excellent Aurora-A-selective inhibitory activity and useful as an anti-cancer agent that can be administered orally; a novel anti-tumor effect enhancer for a microtube agonist comprising a taxane-...  
WO/2013/127727
The invention relates to hormone containing oil-in-water emulsion for parenteral administration comprising progestogen and/or estrogen; a phospholipid comprising one or two omega-3 fatty acid moieties; and an oil as well as a pharmaceuti...  
WO/2013/126963
This invention is directed to an RNA interference (RNAi) agent and the use of that RNAi agent to treat chronic pain in individuals, as well as pharmaceutical compositions containing the RNAi agents of the invention. The DNA-directed RNA ...  
WO/2013/127913
The invention, in a first aspect relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R is a 6-membered aromatic ring, or a 5- or 6-membered heteroaromatic ring comprising 1 to 3 heteroatoms selected...  
WO/2013/128086
The present invention relates to a novel pharmaceutical composition which is in syrup form. This novel composition comprises: modafinil, in the form of its S enantiomer, - excipients, sugar, purified water. Use of the pharmaceutical comp...  
WO/2013/130577
Pharmaceutical compositions for the treatment of nasal congestion or migraine, wherein the pharmaceutical compositions comprise low concentrations of a super-selective subclass of selective α-2 adrenergic receptor agonists.  
WO/2013/127918
The present invention relates to compositions and methods for the treatment of Parkinson's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Parkinson's disease and relate...  
WO/2013/130402
Disclosed is a hemisulfate salt of Compound (I): and crystalline forms of the hemisulfate salt. Also disclosed are methods of using the hemisulfate salt of Compound (I) as a CGRP receptor antagonist, and pharmaceutical compositions compr...  
WO/2013/130890
Heterobicyclic compounds of Formula (I): (I); or a pharmaceutically-acceptable salt, tautomer, or stereoisomer thereof, as defined in the specification, and compositions containing them, and processes for preparing such compounds. Provid...  
WO/2013/129622
The present invention provides a compound having cholinergic muscarinic M1 receptor positive allosteric modulator activity, that is useful as a drug for preventing or treating Alzheimer's disease, schizophrenia, pain, sleep disorders, an...  
WO/2013/130150
Methods and compositions for treating a subject suffering from exposure to a chemical threat agent are disclosed.  
WO/2013/129603
The present invention addresses the problem of developing and providing a method for designating a disease that relates to the amount of TDP-43 existing in cells and a method for producing a TDP-43 binding inhibitor. By collecting cells ...  
WO/2013/129739
The present invention relates to a pharmaceutical composition comprising, as an active ingredient, a polypeptide which contains a bee venom-phospholipase A2 (BV-PLA2) amino acid sequence without a leader sequence for treating or preventi...  
WO/2013/130150  
WO/2013/127917
The present invention relates to compositions and methods for the treatment of amyotrophic lateral sclerosis. More specifically, the present invention relates to novel combinatorialtherapiesfor treating amyotrophic lateral sclerosisor a ...  
WO/2013/127817
This invention is directed to compounds (I), which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acce...  
WO/2013/127293
Provided are a culture medium for preparing neural stem cells and use thereof, the culture medium for preparing neural stem cells comprising: a basic culture medium suitable for the growth of stem cells, and a cell signal pathway inhibit...  
WO/2013/130422
The invention described herein relates to methods for treating mitochondrial diseases. In particular, the invention relates to methods for treating mitochondrial diseases by administering therapeutically effective amounts of one or more ...  
WO/2013/128088
The present invention relates to the use of modafinil in cocaine addiction. The modafinil used is the dextrorotatory enantiomer thereof (modafinil S), having a very rapid release time of less than 1 hour, preferably 15-30 minutes, and ve...  
WO/2013/127345
Provided are compounds as protein kinase inhibitors and use thereof. Preparation methods of the compounds are also provided. The compounds can effectively inhibit the activities of protein kinases and proliferation of abnormal activated ...  
WO/2013/128562
[Problem] To provide an adhesive skin patch containing rivastigmine, in which desired adhesion performance can be achieved satisfactorily and rivastigmine can exist highly stably for a long period without using any antioxidative agent, a...  
WO/2013/129085
The present invention provides a circadian rhythm-improving agent containing lactic acid bacteria or a processed product thereof as an active ingredient.  
WO/2013/124816
A method of generating neural stem cells or motor neurons is disclosed, the method comprising up-regulating a level of at least one exogenous miRNA and/or down-regulating at least one miRNA using an agent which hybridizes to the miRNA in...  
WO/2013/124416
The present invention relates to a calcineurin inhibitor for use in the treatment of a lesional vestibular disorder.  
WO/2013/124026
Compounds of the formula I in which R1, R2 and R4 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of cancer, rheumatoid arthritis and / or systemic lupus  
WO/2013/125878
The present invention relates to: a method for regulating the differentiation of neural stem cells or neural progenitor cells into dopaminergic neurons, comprising the step of increasing or inhibiting the activity of ADAM17 and/or ADAM10...  
WO/2013/124815
A method of qualifying a mesenchymal stem cell (MSC) population is disclosed. The method comprises: (a) ex vivo differentiating a population of mesenchymal stem cells originating from the subject towards a first lineage - specific cell, ...  
WO/2013/125617
This solid pharmaceutical composition is useful as a solid pharmaceutical composition of 1-(3-(2-(1-benzothiophen-5-yl) ethoxy) propyl) azetidin-3-ol, which is excellently elutable and moldable and is stable in long-term storage, or a sa...  
WO/2013/126205
Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of mixed monoamine reuptake inhibitor locally at or near a target site, one can relieve pain caused by diverse sour...  
WO/2013/125634
 Provided are a TLR4 agent, a tissue homeostasis agent, a hepatocyte growth factor inducer, a tissue repairing agent, and a sirtuin inducer using hyaluronic acid fragments. Hyaluronic acid fragments selected from sizes of 2-20 sugar ...  
WO/2013/123766
The present invention relates to a phosphodiesterase 4 inhibitor capable of avoiding vomiting. Formula (I) represents a compound or a prodrug or a solvate, R1 is an independent methoxy, bromine and substituted aryl; X is an optionally su...  
WO/2013/123824
Provided are a polyglycol - naloxone conjugate of general formula (II) and a pharmaceutical composition containing the conjugate. In the conjugate, n is an integer of 1 - 20. Also provided is a conjugate of three - branched or four - bra...  
WO/2013/124158
The present invention relates to the 1 H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3ß) inhibitors and to their use in the treatment of GSK-3p-related disorders such...  
WO/2013/125225
The invention aims to provide a composition for treating atopic dermatitis, bronchial asthma, allergic rhinitis or major depressive disorder (depression), comprising a mixture of Formula antidoti coptidis (orengedokuto) and Formula reple...  
WO/2013/124341
The present invention relates to new substituted pyrazolo[1,5-a]pyridine having a great affinity for sigma receptors, especially sigma-1 receptor, as well as to the process for the preparation thereof, to compositions comprising them, an...  
WO/2013/124817
A method of generating a population of cells useful for treating a nerve disease or disorder in a subject, the method comprising up-regulating a level of at least one exogenous miRNA in mesenchymal stem cells (MSCs) and/or down-regulatin...  
WO/2013/125531
For the purpose of providing a composition, which can effectively ameliorate various sequelae caused by central nerve damage, and a use of the composition, a composition that contains a compound having a CD3 agonistic activity is used.  
WO/2013/124413
The present invention relates to new thiadiazolidmediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is invol...  
WO/2013/125543
Provided is a prophylactic or therapeutic agent for autoimmune diseases (e.g., psoriasis, rheumatoid arthritis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, multiple sclerosis, systemic lupus erythematosus), which ha...  
WO/2013/125135
Provided is an anthocyanin-containing composition which enhances the bioabsorbability of anthocyanins, which have low bioavailability, causes anthocyanins to be more effectively absorbed in vivo, and enhances absorption of anthocyanins i...  
WO/2013/124169
1 H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors. The present invention relates to the 1 H-indazole-3-carboxamide compounds for use as glycogen synthase kinase 3 beta (GSK-33) inhibitors and to their use...  
WO/2013/125722
Provided is a neuroprotective agent screening method comprising an administration step for administering glucose and a test substance to a hypoglycemic encephalopathy model, which is a non-human animal having a flat electroencephalogram ...  

Matches 651 - 700 out of 45,474