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Matches 1 - 50 out of 15,554

Document Document Title
WO/2018/185685A1
The present invention relates to a topical pharmaceutical composition comprising: at least two pharmaceutical agents selected from the group consisting of pentamidine isethionate, ketoconazole and miltefosine; an agent for boosting skin ...  
WO/2018/187623A1
The present invention provides crystalline forms of compound of formula (la) and processes of making the crystalline forms. Also provided are compositions comprising the crystalline forms and crystalline forms for treating or preventing ...  
WO/2018/185346A1
The invention relates to a pharmaceutical composition for systemic, particularly parenteral treatment of infectious diseases, based on an aqueous, sterile and pyrogen-free solution of chlorine dioxide, which contains 5 to 1000 mg/l (ppm)...  
WO/2018/182523A1
The present invention relates to a vaccine for therapeutic or prophylactic treatment of a pathological condition. In particular, the present invention relates to a vaccine for therapeutic or prophylactic treatment of malaria. In an aspec...  
WO/2018/176079A1
This invention relates to berberine alkaloids, formulations thereof and their use for the prevention and/or treatment of infectious disease, especially disease caused by C. perfringens and Eimeria in animals. The invention also relates t...  
WO/2018/183922A1
The present invention provides methods and compositions for immunizing a subject against malaria.  
WO/2018/176093A1
This invention relates to berberine alkaloids, formulations thereof, and their use in the prevention and/or treatment of infectious disease in animals, particularly Lawsonia infection. In particular, the invention relates to berberine al...  
WO/2018/183512A1
A single-dose oral formulation of spinosad and lufenuron and methods for its use in the extended control of a flea infestation on a domestic animal such as a dog without emesis.  
WO/2018/178345A1
The present invention is directed to a salt of a compound of formula (I), R1 is halogen or methyl; X is methyl, OR2, or SR2; Y1, Y2 is CR3 or N, and one of Y1, Y2 is N and one of Y1, Y2 is CR3; R2 is methyl or ethyl; R3 is hydrogen or me...  
WO/2018/175633A1
Provided herein are methods and compositions for vaccinating subjects against malaria, or otherwise promoting the development of an immune response against Plasmodium falciparum. In some aspects, provided here are compositions comprising...  
WO/2018/174170A1
A compound represented by formula (I) has an excellent controlling effect on arthropod pests. (In the formula, Q represents a group represented by formula Q1 or the like; A1 represents CR7 or the like; A2 represents NR8A or the like; A4 ...  
WO/2018/167271A1
The present invention is related to a stable topical veterinary composition comprising:• a) selamectin, • b) dimethyl sulfoxide (DMSO) in an amount between 0.5-15% w/v,• c) an organic solvent and • d) optionally an antioxidant.  
WO/2018/170236A1
The invention relates to inhibitors of calcium-dependent protein kinase 1 (CDPKl) and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as T. gondii, T. cruzi, P. fal...  
WO/2018/167385A1
The present invention relates to a composition comprising pyrethrum for the control of target arthropod pests on a human or animal to be treated. The composition comprises a synergic mixture as an active agent, consisting of pyrethrum, a...  
WO/2018/166427A1
Provided are a Streptomyces avermitilis strain C63-51 with a high yield of ivermectin B1b and a method for producing ivermectin B1b by using this strain. By using the above-mentioned strain and method, efficient production of single iver...  
WO/2018/161291A1
Provided in the present invention is an eprinomectin nanoemulsion, the eprinomectin nanoemulsion containing eprinomectin, a solvent and a long-chain monoester; the monoester is represented by the formula R-COO-R', wherein R is selected f...  
WO/2018/161938A1
A gynecological vaginal wash for adjusting female vaginal microecology and a preparation method thereof. The wash is prepared by adding a natural fragrance to acidic water with an acidic water volume concentration of 0.01-0.5% and adjust...  
WO/2018/162312A1
The present invention relates to novel spiro compounds of formula I, wherein the variables have the meanings as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their ...  
WO/2018/160845A1
This application describes compounds, compositions, and methods which are useful in treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite.  
WO/2018/157874A1
Disclosed are a dihydroartemisinin diploid derivative, a pharmaceutical composition thereof, and an application. The derivative is an artemisinin diploid, used for drugs treating or preventing malaria caused by plasmodium, drugs treating...  
WO/2018/153957A1
The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating intracellular bacterial, fungal, and protozoal infections.  
WO/2018/157083A1
Plasmodium P47 D2 polypeptides, products, compositions and kits containing such polypeptides and methods (processes) of making and using such polypeptides in analytical, research, diagnostic and human and animal health applications. Also...  
WO/2018/152602A1
The present invention relates, in general, to a combination of Crotamine and drugs used for therapy. More specifically, the present invention relates to a combination of Crotamine, a toxin from the snake Crotalus durissus terrificus, and...  
WO/2018/149909A1
The present invention relates to pharmaceutical compositions for the treatment of helminthiasis, which comprise the active ingredient felodipine or a pharmaceutically suitable salt or solvate thereof. The invention relates in particular ...  
WO/2018/148186A1
Provided herein are immunogenic compositions containing recombinant proteins capable of presenting all, or antigenic portions of, the Eimeria tenella Elongation Factor 1 alpha, or EF-1α, protein in the development of active immunity to,...  
WO/2018/148660A1
Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The ...  
WO/2018/141063A1
Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one em...  
WO/2018/141029A1
The present invention relates to immunogenic polypeptides, immunogenic fragments thereof and compositions comprising same, for use in eliciting an immune response in a subject to a tick. The invention also provides for methods of using s...  
WO/2018/142288A1
The invention relates to compounds and pharmaceutical compositions for use in treating malaria infections. The invention also relates to uses and methods of treating a malaria infection in a subject using the compounds and pharmaceutical...  
WO/2018/139436A1
The present invention provides: a heterocyclic compound which exhibits an excellent controlling effect against harmful arthropods and which is represented by formula (I) (in the formula, Q denotes a group represented by Q1 or the like, A...  
WO/2018/140533A1
Compositions are provided that contain sporulated coccidial oocysts, wherein the compositions are free of antibiotics and comprise formalin at a concentration sufficient to inhibit microbial growth for at least 12 months while maintainin...  
WO/2018/132882A1
The present invention pertains to the field of the production of recombinant proteins, using a synthetic gene for increased expression of the protein in Pichia pastoris. More specifically, the invention describes the production of the re...  
WO/2018/129618A1
The present disclosure relates to compounds of Formula (I) which are multimeric forms of a monomeric binding peptide linearly bonded to PEG moieties to form the multimers. The multimeric forms stimulate angiogenesis and promote wound hea...  
WO/2018/130853A1
The present invention relates to novel compounds and pharmaceutically acceptable salts or solvates thereof which have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such...  
WO/2018/124129A1
The present invention addresses the problem of developing and providing a novel agricultural and horticultural insecticide due to factors such as the development of pests resistant to existing chemicals since damage by pests is still a m...  
WO/2018/124088A1
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...  
WO/2018/124181A1
The present invention provides a functionalized mRNA including mRNA and double-stranded RNA including at least one RNA oligomer hybridized with mRNA. Functionalized mRNA is provided according to this configuration.  
WO/2018/124896A1
The subject of the invention is a composition for prevention and control of bee diseases and the use of the hemp oil for preparation of the composition. In more detail, the invention relates to a composition comprising hemp essential oil...  
WO/2018/115532A1
The invention relates to a composition comprising at least one compound of formula I R-SOa-S-R' (I), in which a is equal to 1 or 2 and R and R' are, independently of one another, a linear or branched C1-C5 alkyl group, for use in the pre...  
WO/2018/118979A1
The present disclosure relates to the use of hepcidin in therapeutic methods for the treatment of various conditions in which decreasing serum iron concentration may be beneficial.  
WO/2018/116945A1
A compound represented by formula (I) or a salt thereof; and a pest control agent which contains, as an active ingredient, at least one substance selected from the group consisting of compounds represented by formula (I) and salts thereo...  
WO/2018/107284A1
Sprayable compositions comprising a pyrethroid, a viscosity building agent, an emulsifier or surfactant, and an emollient are provided. The compositions have a viscosity that allows for delivery of the spray from a pressurized container ...  
WO/2018/106966A1
Methods and compositions for preventing and/or treating diseases and conditions caused by certain apicomplexan infections are provided. The methods involve administering/providing to a subject one or more of tartrolon D and E, including ...  
WO/2018/105632A1
The present invention addresses the problem of developing and providing a novel insecticide for agricultural and horticultural use since pests still cause extensive damage on the production of agricultural and horticultural crops and pes...  
WO/2018/100178A1
The invention provides a method for the production of a zeolite particle composition which has optimized characteristics, such as enhanced adsorption and specific ion exchange properties. A method and an apparatus for producing improved ...  
WO/2018/100292A1
The invention relates to the use of a bacterial mixture for the prevention and improvement of the state of ungulates suffering from pathologies involving a parasitic or bacterial infection of the foot, said composition comprising: at lea...  
WO/2018/096087A1
The present invention relates to a veterinary composition comprising diminazene and levamisole or salts thereof, wherein the weight ratio of diminazene or its salts to levamisole or its salts ranges from 0.50 to 2.00. The present inventi...  
WO/2018/094100A1
Disclosed herein are compositions comprising complexes of cyclodextrins and lipid- modified stem cell proteins. Also disclosed are topical compositions the complexes. Methods of using the compositions for the therapeutic purposes are als...  
WO/2018/090100A1
The present disclosure relates to methods and products for reducing resistance to anti-parasitic agents. In certain embodiments, the present disclosure provides a method of reducing resistance to an anti-parasitic agent in an animal suff...  
WO/2018/088509A1
The present invention provides a polypeptide and a malaria vaccine comprising said polypeptide, the polypeptide comprising any of the following amino acid sequences: (a) an amino acid sequence represented by SEQ ID NO. 4; (b) an amino ac...  

Matches 1 - 50 out of 15,554