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Matches 1 - 50 out of 9,413

Document Document Title
WO/2015/028850A1
Provided are cytotoxic agents, pyrrolo[2,1-c][1,4]benzodiazepine (PBD) derivatives, their conjugates with a cell-binding agent, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infe...  
WO/2015/027565A1
An L-carnitine micro-capsule powder and preparation method thereof, the L-carnitine micro-capsule powder comprising: L-carnitine, maltodextrin, arabic gum, gelatin, and sodium ascorbate; the preparation method comprises the following ste...  
WO/2015/030106A1
The present invention relates to compounds represented by general formula (I) (where Z, R, Ra, R', * and n are each as defined in the description) or salts thereof.  
WO/2015/028027A1
The present disclosure concerns monoclonal antibodies directed to the pro-domain of ADAM 12 and their use in the treatment of cancer.  
WO/2015/028286A1
A polymer of formula (I) where X1 and X2 respectively represent the alpha and omega end groups of the polymer; R1 represents a hydrogen atom or a straight or branched chain alkyl group; R2 represents a straight or branched chain alkyl gr...  
WO/2015/025528A1
The present invention addresses the problem of providing a novel free radical scavenger which can solve problems occurring in existing free radical production inhibitors/scavengers, such as the induction of inflammation. Specifically, th...  
WO/2015/024100A1
A method of providing anesthesia and organ-protection to a subject in need thereof comprises co-administering to the subject a non-anesthetic protective gas in an amount effect to provide organ protection, and a liquid anesthetic agent i...  
WO/2015/020138A1
 The purpose of the present invention is to provide a means for promoting the in vivo absorption of hydroxytyrosol or a derivative thereof, prolonging the in vivo residence time, and sustaining the effect. As a result of in-depth studi...  
WO/2015/015989A1
The purpose of the present invention is to provide an agent for alleviating side effects in cancer chemotherapy, said agent being capable of alleviating various side effects in cancer chemotherapy and thus increasing the treatment comple...  
WO/2015/014209A1
Provided in the present invention is a method for detoxification in healthy human beings and lung disease patients using pyruvate pharmaceutical compositions. Toxins accumulated in mammalian cells because of smoking and air pollution can...  
WO/2015/010498A1
A natural herb composition for rapidly cleaning body metabolic toxins is prepared by using the following raw materials in part by mass, the raw materials comprise a mangosteen extract, an aloe extract, and a hot-water extract of a mixtur...  
WO/2015/008317A1
The present invention addresses the problem of providing a hydrogen sulfide production-inducing agent that has a higher efficiency and a lower toxicity than L-cysteine. The present invention is characterized in that, by administering D-c...  
WO/2015/005060A1
Provided is a method for producing an ellagic acid composition which has excellent solubility in water. A method for producing an ellagic acid composition, which comprises: a step wherein a heat treatment starting material is prepared by...  
WO/2015/002061A1
Provided is a medicinal active ingredient which is useful for treating or preventing inflammatory diseases, diseases caused by lipid oxidation, retinochoroidal disorders, etc. The present invention is a phenylimidazole derivative represe...  
WO/2014/205551A1
A method of treating sepsis comprises administering an agent that inhibits the activity of an miRNA that is upregulated in sepsis.  
WO/2014/197250A1
An orally deliverable dosage system comprises (a) iron in a form of one or more physiologically acceptable iron grades, compounds and/or complexes; and (b) an agent to mitigate one or more gastrointestinal adverse effects of unabsorbed i...  
WO/2014/195416A1
The invention relates to a chelate resulting from the complexing of a trans-di-N-picolinate tetraazacycloalkane ligand with a metal cation, said ligand corresponding to formula (A) wherein n is equal to 0 or to 1, R is H or a C1-C18 alky...  
WO/2014/194809A1
Provided in the present invention are new compounds having the triple activities of thrombolysis, antithrombotic and radical scavenging as represented by general formula (I), wherein T is a connecting arm having at least two groups for c...  
WO/2014/188046A1
The invention relates to neuroprotective, antioxidant steroidal nitrones to which the blood-brain barrier is highly permeable, as potential drugs for the treatment of a cerebral stroke or ischaemia, Alzheimer and Parkinson disease and am...  
WO/2014/187291A1
The present invention discloses a mercaptonicotinic acid compound and preparation method and use thereof; the structural formula of the compound is as shown in Formula I. Experimentation demonstrates that the mercaptonicotinic acid compo...  
WO/2014/183555A1
The present invention relates to a cycloalkyl acid derivative, a preparation method thereof, and a pharmaceutical application thereof, and in particular, the present invention relates to a cycloalkyl acid derivative represented by genera...  
WO/2014/180238A1
The present invention discloses an antihypoxic pharmaceutical composition and application thereof. The pharmaceutical composition contains vinpocetine and L-carnitine or a derivative thereof and a pharmaceutically acceptable salt thereof...  
WO/2014/180248A1
The present invention relates to an oral pharmaceutical composition for increasing hypoxia tolerance, characterized in that the pharmaceutical composition comprises active ingredient L-carnitine or derivative thereof or pharmaceutically ...  
WO/2014/180239A1
The present invention provides a pharmaceutical composition used for treating severe altitude sickness, characterized by a composition consisting of trimetazidine or pharmaceutically acceptable salt thereof and L-carnitine or derivative ...  
WO/2014/180240A1
The present invention discloses a slow-release agent for increasing hypoxia tolerance; the slow-release agent is a composition formed by combining trimetazidine or pharmaceutically acceptable salt thereof and L-carnitine or derivative th...  
WO/2014/175180A1
A quercetin glycoside and a fructooligosaccharide in a ratio (by weight) of 1 to at least 0.1 are incorporated to produce a quercetin glycoside-containing oral composition and to mitigate the bitterness of the quercetin glycoside contain...  
WO/2014/173174A1
The present invention describes a reduction type coenzyme Q10 powder, a composition thereof, and a preparation method thereof. The reduction type coenzyme Q10 powder is obtained by reacting an oxidation type coenzyme Q10 with the presenc...  
WO/2014/170801A1
According to the invention, a thermus thermophilus fermentation medium (INCI name "Thermus thermophilus Ferment" marketed by Sederma under the trade name VENUCEANE™) is used to prevent and/or treat damages associated with infrared radi...  
WO/2014/169542A1
Disclosed is a veterinary drug composition for preventing and treating mycotoxin poisoning, and a formulation and preparation method thereof. The veterinary drug composition for preventing and treating mycotoxin poisoning is prepared fro...  
WO/2014/171854A1
The invention relates to the pharmaceutical industry and to the field of medicine. The problem addressed by the present invention is the creation of an effective antioxidant pharmaceutical composition. The problem is solved in that an an...  
WO/2014/168523A4
The present invention relates to novel biologically active compounds being dicarboxylic acid bisamide derivatives of general formula (I), or pharmaceutically acceptable salts thereof, which are capable of complexing or chelating metal io...  
WO/2014/168523A1
The present invention relates to novel biologically active compounds being dicarboxylic acid bisamide derivatives of general formula (I), or pharmaceutically acceptable salts thereof, which are capable of complexing or chelating metal io...  
WO/2014/154131A1
Provided are a caffeoyl substituted pentacyclic triterpene derivative as represented by formula (I) and pharmaceutical composition containing the same. Also provided are uses of the derivative in the preparation of drugs or health-care p...  
WO/2014/154927A1
The invention relates to the use of the inhibitor of the activity of the steroid sulfatase enzyme STX64 for treating aging, and thus for increasing the longevity of individuals or improving their quality of life. The invention also relat...  
WO/2014/148422A1
An extraction composition produced from licorice (scientific name: Glycyrrhiza), which is characterized by containing glycyrrhetinic acid and a salt thereof (an extraction component (A)) in an amount of 0.5 to 20 wt% relative to the weig...  
WO/2014/150413A1
Described herein is a new antidote for the rapid elimination of carbon monoxide from hemoglobin, including brain, heart, and red cell hemoglobin. The disclosed therapy involves the use of modified human globins, particularly neuroglobins...  
WO/2014/146044A1
Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood l...  
WO/2014/138920A1
The present invention relates to a method for extracting shrimp oil. Particularly, shrimp processing water (EPC) is recovered and subjected to a dissolved air flotation (DAF) system after adding a flocculating agent. The suspended and di...  
WO/2014/136079A1
Orally administerable deferasirox formulations are disclosed having reduced release under gastric conditions and fast release at near neutral pH or at neutral pH.  
WO/2014/136944A1
The present invention addresses the problem of providing an aqueous liquid composition which is suitable for oral ingestion and includes a high concentration of histidine, a method for preparing the liquid composition, and uses, and the ...  
WO/2014/127475A9
A composition for the treatment of perianal disorders. In particular, the composition includes three components: a) an analgesic, b) a cryoprotective agent and c) a muscle relaxant.  
WO/2014/129614A1
The purpose of the present invention is to provide an orally administered adsorbent capable of adsorbing large quantities of tryptophan or indoxyl sulfate in the presence of bile acid. Accordingly, an orally administered adsorbent is cha...  
WO/2014/127475A1
A composition for the treatment of perianal disorders. In particular, the composition includes three components: a) an analgesic, b) a cryoprotective agent and c) a muscle relaxant.  
WO/2014/129618A1
The purpose of the present invention is to provide surface-modified spherical active carbon exhibiting excellent adsorption capacity with respect to uremic substances in the body, and particularly with respect to β-aminoisobutyric acid....  
WO/2014/129617A1
The purpose of the present invention is to provide spherical active carbon exhibiting excellent adsorption capacity with respect to uremic substances in the body, and particularly with respect to β-aminoisobutyric acid. Accordingly, pro...  
WO/2014/129616A1
The purpose of the present invention is to provide an orally administered adsorbent capable of adsorbing large quantities of tryptophan or indoxyl sulfate in the presence of bile acid. Accordingly, an orally administered adsorbent is cha...  
WO/2014/126596A1
The neuroprotective multifunctional antioxidants are compounds that contain a 2-diacetylamino-5-hydroxypyrimidine moiety, having the structural formula: wherein R1 is CH2 or C2H4; R2 is H or -OR4 where R4 is H or aryl; and R3a and R3b ar...  
WO/2014/124059A3
Compounds, compositions and methods related to the prevention or treatment of isoprostane-mediated tissue damage in a mammalian subject in need thereof.  
WO/2014/124140A1
Methods, compositions and kits for the prevention and treatment of mitochondrial dysfunction, mitochondrial DNA damage and genomic DNA damage are provided. The methods use the administration of palm fruit juice and/or compositions contai...  
WO/2014/116723A1
This disclosure provides compositions, kits, and methods useful for treating or preventing viral and bacterial infection and reducing or preventing the effects of toxins. The methods comprise administering to a subject an effective amoun...  

Matches 1 - 50 out of 9,413