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WO/2001/096306A1 |
The invention relates to a method that can be used on a large scale for dynamic enantiomer separation of piperidone derivatives of general formula (1), wherein R?1¿, R?2¿, R?3¿ and n can have the meanings given in the description and ...
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WO/2001/094457A2 |
A process is disclosed for recovering polyamide material from post-industrial and post-consumer products containing the polyamide material and insoluble materials. The process includes the steps of: (a) contacting the post-industrial and...
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WO/2001/094302A2 |
A process for the purification and isolation of a chemical compound, by extractive solution crystallization. The process comprises combining in any order a first solvent, a second solvent, and a mixture comprising a chemical compound wit...
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WO/2001/091874A1 |
The invention relates to a device and to a method for crystallizing substances from solutions or dispersions containing said substances in a crystallizer that comprises a classifying zone (3) and that is further provided with a) an inner...
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WO/2001/091875A1 |
A continuous vacuum pan includes a cylindrical housing having a vertical axis; at least one liquid heating pan within the housing; a vertical tube, floating calandria within the liquid heating pan, the vertical tube floating calandria ha...
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WO/2001/090041A1 |
The invention relates to a method for the selective crystallization of poly- or monomethylol alkanoic acids of the general formula (I), wherein R is the same or different and represents a methylol group or a substituted or unsubstituted ...
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WO/2001/090040A2 |
The invention relates to a method for isolating poly- or monomethyl alkanoic acids of the general formula (I), wherein R is the same or different and represents a substituted or unsubstituted hydrocarbon or a methylol group that is produ...
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WO/2001/087836A1 |
The invention concerns the $g(b) crystalline form of the compound of formula (I), characterised by its X-ray diffraction pattern on powder. The invention is useful for preparing medicines
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WO/2001/087835A1 |
The invention concerns $g(a) crystalline form of the compound of formula (I), characterised by its X-ray diffraction pattern on powder. The invention is useful for preparing medicines.
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WO/2001/083439A2 |
The invention concerns a $g(g) crystalline form of a compound of formula (I) characterised by its X-ray diffraction pattern on powder. The invention is applicable to medicines.
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WO2000057980A9 |
A new EFG (Edge-defined Film-fed Growth) crucible/die (20A) and susceptor (40A) interface design is provided which (a) overcomes the tendency for silicon feed material to form a solid mass near the hub region and (b) prevent the crucible...
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WO/2001/080963A1 |
The efficient physical process for freeze concentration of aqueous solutions is based on ice crystal transformation, which results in very rapid growth of ice crystals and grain-shaped and agglomerated large crystals without inside entra...
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WO/2001/079214A1 |
Chloride is selectively isolated as NaCl from N-phosphonomethyliminodiacetic acid process wastes by evaporative crystallization of the caustic neutralized brine.
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WO/2001/074332A1 |
A method for making a composition comprising active particles comprising an active substance comprises the steps of a) providing an emulsion having a dispersed phase comprising a solution of the active substance in a solvent and b) induc...
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WO/2001/075415A2 |
A device for promoting protein crystal growth (PCG) using microfluidic channels. A protein sample and a solvent solution are combined within a microfluidic channel having laminar flow characteristics which forms diffusion zones, providin...
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WO/2001/074749A1 |
An alternative and improved method for cleaning cooling and/or crystallization surfaces of a crystallizer fouled with a crystallized bisphenol as a result of processing a slurry derived from the production of bisphenol is provided. The m...
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WO2001036325B1 |
A separator for separating a meltable solid from a mixture with other solids has a tank for holding a fluid; a container at least partially inside the tank, made at least in part of a screen through which the fluid can pass and melted so...
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WO/2001/072736A1 |
A method for purification of cyclic ester, which comprises feeding a crude cyclic ester as raw material crystals to an inlet (3) for raw material crystals disposed at a lower portion of a purification tower (1) being cylindrical and exte...
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WO/2001/070740A1 |
A process for producing crystalline form I of cabergoline, which process comprises crystallization of the desired form from a toluene/diethyl ether mixture comprising raw cabergoline, followed by recovery and drying of the resulting crys...
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WO/2001/070744A2 |
The present invention provides a process for the synthesis of compounds of formula (II), or pharmaceutically acceptable salts thereof.
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WO/2001/070721A1 |
The invention concerns a method for purifying the dimeric cyclic ester of lactic (or glycolic) acid starting from a raw lactide (or glycolide) comprising impurities, the method consisting in: extractive and controlled crystallization of ...
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WO/2001/066215A1 |
A method for repeatedly converting a solvent from a state of solvent to a state of antisolvent with relatively little loss of solvent. The method is used to allow for processing of large amounts of solute material with minimum amounts of...
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WO/2001/066508A2 |
A process for recovering a desired organic acid from a solution includes the steps of: providing an aqueous solution including at least one desired organic acid or its acid anion; adjusting the proton concentration in the aqueous solutio...
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WO2001006227B1 |
The invention relates to the composition, production and use of luminescent microparticles and nanoparticles. These particles can either be used as internal standards for referencing fluorescence signals, or as markers for marking and de...
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WO/2001/056956A1 |
The invention relates to a process for the crystallization of substances having a narrow metastable supersaturation zone. In the process the saturation of a solution is gradually increased and the solution is seeded for the crystallizati...
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WO/2001/045850A1 |
The present invention consists in a particle classifier for segregating particles of a predetermined size or density range from a suspension of the particles wherein the size and/or density of the suspended particles varies with time, th...
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WO/2001/046105A1 |
The invention relates to a method for producing Bis(4-hydroxyaryl)alkanes of high purity from adducts of Bis(4-hydroxyaryl)alkanes and aromatic hydroxy compounds which are obtained by means of acid-catalysed conversion of the aromatic hy...
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WO/2001/046148A1 |
A process for the manufacture of the (-) trans piperidine carbinol (1) by a process comprising contacting a racemic mixture of the piperidine carbinol in solution with (-)-ditoluoyltartaric acid, crystallising the (-)-ditoluoyltartaric a...
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WO/2001/046104A1 |
The invention relates to a method for separating Bis(4-hydroxyaryl)alkanes from adducts of Bis(4-hydroxyaryl)alkanes with aromatic hydroxy compounds. The crystallised, filtered and purified Bis(4-hydroxyaryl)alkane/arylhydroxy adducts wh...
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WO/2001/042134A1 |
The present invention relates to a novel crystalline disodium pamidronate 3∼4hydrate and a process for preparing it. More particularly, crystalline disodium pamidronate 3∼4hydrate of formula (I) having the water content of 17.0∼20....
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WO/2001/034574A1 |
The present invention relates to a stable crystalline form of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinami
ne hydrochloride designated the B polymorph, its production in essentially pure form, and its use. The invention a...
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WO/2001/032125A2 |
Novel Apparatus and Process for Preparing Crystalline Particles An apparatus for preparing crystalline particles of a substance suitable for inhalation therapy comprises (i) a first reservoir 3 of said substance dissolved in a liquid sol...
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WO/2001/030759A2 |
NHE-1 inhibitor crystal of Formula (I), methods of using such NHE-1 inhibitor crystal and pharmaceutical compositions containing such NHE-1 inhibitor crystal. The NHE-1 inhibitor crystal is useful for the reduction of tissue damage resul...
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WO/2001/028958A1 |
The invention is directed to a process for recovering a crystalline material from an aqueous solution, which solution also contains organic contaminants, in which process the material is crystallised from the aqueous solution by freeze c...
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WO/2001/014036A1 |
The method of producing fine medicament particles suitable for inhalation, particles produced by the method and apparatus suitable for carrying out the method is claimed. The method comprises contacting a stream or streams of a solution ...
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WO/2001/014290A1 |
An apparatus for purifying crystals wherein an opening (3) for charging crystals of a raw material and an opening (4) for withdrawing out purified crystals as a product are disposed at a lower portion and an upper portion, respectively, ...
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WO/2001/014037A1 |
A crystallization apparatus having an agitating vessel, a liquid circulating means which circulates a liquid or slurry along the wall of the agitating vessel and one or more means for generating a temperature difference which can generat...
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WO/2001/013050A1 |
Disclosed is a process and apparatus for transferring heat from a heat source at a first temperature (16) to a heat sink at a second higher temperature (17) in a phase change of a heat transfer fluid. The heat transfer fluid is subjected...
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WO/2001/010813A1 |
Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, fluvastatin and cervastatin and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as antihypercholesterolemic agents. The majority of th...
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WO/2001/010830A2 |
The present invention provides a process for producing crystals of a polymorphic compound in a first crystal structure by introduction of the compound in a second crystal structure into a saturated brine solution of the compound under co...
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WO/2000/079095A1 |
A composition for reducing deposition of a mineral salt from an aqueous supersaturated solution onto a solid surface in contact with the aqueous supersaturated solution which composition comprises a dispersion of either (i) seed crystals...
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WO/2000/078445A1 |
A method is provided for performing array microcrystallizations to determine suitable crystallization conditions for a molecule. The method comprises forming an array of microcrystallizations, each microcrystallization comprising a drop ...
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WO/2000/077082A1 |
The invention relates to a method of separating polyolefinic synthetic mixtures, based on a polyolefinic synthetic fraction or a synthetic mixture as the starting material. According to the inventive method, said starting material is con...
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WO/2000/072934A1 |
The invention relates to a method for crystallizing an aqueous solution. According to the invention, said method consists in the following steps: at least one surfactant is initially added to the aqueous solution if the aqueous solution ...
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WO/2000/072692A1 |
The present invention relates to a method and a system for concentration of a liquid product said liquid product comprising crystallizable components, comprising the steps of heating the liquid product having a dry solid contentof at lea...
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WO/2000/067872A2 |
A filtration assembly operable in connection with a crystal form screening workstation is disclosed that provides for automated crystal form screening. The assembly comprises first and second valves, with each valve having an internal pa...
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WO/2000/058671A1 |
A source fluid from which solid material forms when it is cooled is passed through apparatus which defines a continuous reentrant lumen (12). The lumen has a thermally conductive processing wall (15) from which heat is extracted from the...
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WO/2000/056416A1 |
The invention relates to a method for controlling the crystal size during continuous mass crystallisation, especially with ammonium sulphate. According to said method, seed products are added, the seed product being produced independentl...
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WO/2000/054865A1 |
A method for purifying substances through emulsion crystallisation is described, whereby (a) an emulsion of organic liquid droplets in a continuous water phase containing the impure substance is formed; (b) the emulsion is super-saturate...
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WO/2000/053283A1 |
A process for isolating enantiomer components from a mixture of enantiomers through co-crystallization is disclosed, comprising the steps of (a) forming a solution comprising the mixture of enantiomers (R) and (S) and co-crystallization ...
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