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WO/2001/046105 |
The invention relates to a method for producing Bis(4-hydroxyaryl)alkanes of high purity from adducts of Bis(4-hydroxyaryl)alkanes and aromatic hydroxy compounds which are obtained by means of acid-catalysed conversion of the aromatic hy...
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WO/2001/046104 |
The invention relates to a method for separating Bis(4-hydroxyaryl)alkanes from adducts of Bis(4-hydroxyaryl)alkanes with aromatic hydroxy compounds. The crystallised, filtered and purified Bis(4-hydroxyaryl)alkane/arylhydroxy adducts wh...
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WO/2001/046148 |
A process for the manufacture of the (-) trans piperidine carbinol (1) by a process comprising contacting a racemic mixture of the piperidine carbinol in solution with (-)-ditoluoyltartaric acid, crystallising the (-)-ditoluoyltartaric a...
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WO/2001/042134 |
The present invention relates to a novel crystalline disodium pamidronate 3∼4hydrate and a process for preparing it. More particularly, crystalline disodium pamidronate 3∼4hydrate of formula (I) having the water content of 17.0∼20....
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WO/2001/036325 |
A separator for separating a meltable solid from a mixture with other solids has a tank for holding a fluid; a container at least partially inside the tank, made at least in part of a screen through which the fluid can pass and melted so...
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WO/2001/034574 |
The present invention relates to a stable crystalline form of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinami
ne hydrochloride designated the B polymorph, its production in essentially pure form, and its use. The invention a...
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WO/2001/032125 |
Novel Apparatus and Process for Preparing Crystalline Particles An apparatus for preparing crystalline particles of a substance suitable for inhalation therapy comprises (i) a first reservoir 3 of said substance dissolved in a liquid sol...
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WO/2001/030759 |
NHE-1 inhibitor crystal of Formula (I), methods of using such NHE-1 inhibitor crystal and pharmaceutical compositions containing such NHE-1 inhibitor crystal. The NHE-1 inhibitor crystal is useful for the reduction of tissue damage resul...
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WO/2001/028958 |
The invention is directed to a process for recovering a crystalline material from an aqueous solution, which solution also contains organic contaminants, in which process the material is crystallised from the aqueous solution by freeze c...
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WO/2001/024921 |
A gallium nitride growth process forms crystalline gallium nitride. The process comprises the steps of providing a source gallium nitride (15); providing mineralizer (17); providing solvent (17); providing a capsule (10); disposing the s...
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WO/2001/014290 |
An apparatus for purifying crystals wherein an opening (3) for charging crystals of a raw material and an opening (4) for withdrawing out purified crystals as a product are disposed at a lower portion and an upper portion, respectively, ...
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WO/2001/014037 |
A crystallization apparatus having an agitating vessel, a liquid circulating means which circulates a liquid or slurry along the wall of the agitating vessel and one or more means for generating a temperature difference which can generat...
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WO/2001/014036 |
The method of producing fine medicament particles suitable for inhalation, particles produced by the method and apparatus suitable for carrying out the method is claimed. The method comprises contacting a stream or streams of a solution ...
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WO/2001/013050 |
Disclosed is a process and apparatus for transferring heat from a heat source at a first temperature (16) to a heat sink at a second higher temperature (17) in a phase change of a heat transfer fluid. The heat transfer fluid is subjected...
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WO/2001/010830 |
The present invention provides a process for producing crystals of a polymorphic compound in a first crystal structure by introduction of the compound in a second crystal structure into a saturated brine solution of the compound under co...
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WO/2001/010813 |
Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, fluvastatin and cervastatin and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as antihypercholesterolemic agents. The majority of th...
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WO/2001/006227 |
The invention relates to the composition, production and use of luminescent microparticles and nanoparticles. These particles can either be used as internal standards for referencing fluorescence signals, or as markers for marking and de...
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WO/2001/002075 |
A method to prepare new polymorphs of materials which have not been observed or to obtain a known polymorph under different conditions than those in which it is usually made by using a laser to cause nucleation and crystal growth to occu...
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WO/2000/078445 |
A method is provided for performing array microcrystallizations to determine suitable crystallization conditions for a molecule. The method comprises forming an array of microcrystallizations, each microcrystallization comprising a drop ...
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WO/2000/079095 |
A composition for reducing deposition of a mineral salt from an aqueous supersaturated solution onto a solid surface in contact with the aqueous supersaturated solution which composition comprises a dispersion of either (i) seed crystals...
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WO/2000/077082 |
The invention relates to a method of separating polyolefinic synthetic mixtures, based on a polyolefinic synthetic fraction or a synthetic mixture as the starting material. According to the inventive method, said starting material is con...
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WO/2000/072934 |
The invention relates to a method for crystallizing an aqueous solution. According to the invention, said method consists in the following steps: at least one surfactant is initially added to the aqueous solution if the aqueous solution ...
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WO/2000/072692 |
The present invention relates to a method and a system for concentration of a liquid product said liquid product comprising crystallizable components, comprising the steps of heating the liquid product having a dry solid contentof at lea...
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WO/2000/067872 |
A filtration assembly operable in connection with a crystal form screening workstation is disclosed that provides for automated crystal form screening. The assembly comprises first and second valves, with each valve having an internal pa...
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WO/2000/057980 |
A new EFG (Edge-defined Film-fed Growth) crucible/die (20A) and susceptor (40A) interface design is provided which (a) overcomes the tendency for silicon feed material to form a solid mass near the hub region and (b) prevent the crucible...
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WO/2000/058671 |
A source fluid from which solid material forms when it is cooled is passed through apparatus which defines a continuous reentrant lumen (12). The lumen has a thermally conductive processing wall (15) from which heat is extracted from the...
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WO/2000/056416 |
The invention relates to a method for controlling the crystal size during continuous mass crystallisation, especially with ammonium sulphate. According to said method, seed products are added, the seed product being produced independentl...
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WO/2000/054865 |
A method for purifying substances through emulsion crystallisation is described, whereby (a) an emulsion of organic liquid droplets in a continuous water phase containing the impure substance is formed; (b) the emulsion is super-saturate...
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WO/2000/053282 |
The invention relates to a process for the crystallisation of a chemical substance, and more particularly a substance to be used as a pharmaceutically active agent.
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WO/2000/048731 |
A process for the conversion of a substantially fluid phase substrate by heterogeneous contact of the substrate or a fragment or derivative thereof with a substantially solid phase agent wherein the solid phase agent is comprised as a su...
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WO/2000/048729 |
A reactor including a rotatable disc (3) having a trough (13) in an upper surface (5) thereof. Reactant (15) is supplied to the trough (13) by way of a feed (4), the disc (3) is rotated at high speed, and the reactant (15) spills out of ...
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WO/2000/048732 |
A reactor including a rotatable disc (3) having first (5, 19) and second (20, 30) surfaces. Reactant (15) is supplied to the first surface (5, 19) by way of a feed (4), the disc (3) is rotated at high speed, and the reactant (15) forms a...
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WO/2000/048730 |
A reactor including a rotatable disc (3) having a surface (5) onto which reactant (15) is supplied by way of a feed (4). The disc (3) is rotated at high speed, and the reactant (15) spills over the surface (5) so as to form a film (17). ...
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WO/2000/048728 |
A reactor including a rotatable disc (3) having a surface (5) onto which reactant (15) is supplied by way of a feed (4). The disc (3) is rotated at high speed, and the reactant (15) spills over the surface (5) so as to form a film (17). ...
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WO/2000/045928 |
The invention relates to a method and a device for purifying mixtures of substances by means of optionally, fractional crystallisation. During the crystallisation process, impurities can precipitate in addition to the desired product, si...
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WO/2000/044468 |
A process is provided for the crystallization of pharmaceutical compounds by colliding a liquid jet stream (12) containing a pharmaceutical compound, such as Z-3-[1-(4-chlorophenyl)-1(4-methylsulfonylphenyl)methylene]-
dihydrofuran-2-one...
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WO/2000/043361 |
A method of purifying 1$g(a)-hydroxyvitamin D¿2? to obtain 1$g(a)-hydroxyvitamin D¿2? in crystalline form. The method includes the steps of boiling a solvent selected from the group consisting of ethyl formate, ethyl acetate and a 2-pr...
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WO/2000/041985 |
A process for the formation of a purified anhydrosugar alcohol is disclosed, whereby the resultant purified anhydrosugar alcohol has a purity of at least 99.8 % and is substantially colorless. The anhydrosugar alcohol is purified by dist...
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WO/2000/038811 |
There is provided according to the present invention a process for preparing crystalline particles, especially particles of a pharmaceutical or carrier substance suitable for inhalation therapy, in addition to an apparatus for the prepar...
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WO/2000/038812 |
The invention relates to a method for producing crystals from thermally sensitive solids. According to this method, the solid is dissolved in at least one solvent and the solution is concentrated by drawing off the solvent to beyond the ...
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WO/2000/039121 |
The present invention relates to a new process for the preparation of an acetate salt of a compound of formula (1) in which R?1¿ is a substituted phenyl group, preferably 3,4-methylenedioxyphenyl; the process comprising treating a solut...
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WO/2000/037420 |
A method for efficient removal of lead co-catalyst species from organic process streams arising from diaryl carbonate synthesis, by contacting the organic reaction mixtures with an aqueous acid, salt, or acid/salt solution, thereby extra...
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WO/2000/032589 |
The present invention provides eletriptan hydrobromide monohydrate of formula (I) together with processes for preparing, uses of, and compositions containing, said monohydrate.
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WO/2000/030613 |
The invention provides a process for preparing essentially crystalline particles containing a substance in solvated form, by dissolving the substance in a first solvent, introducing the solution and a supercritical or subcritical fluid i...
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WO/2000/029102 |
A device and method for simultaneously concentrating a plurality of samples in small volumes based on the principle of crystallization. The device comprises a device for concentrating a plurality of samples comprising: a first temperatur...
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WO/2000/027804 |
Disclosed is the crystallization of Iopamidol using a mixture of an alcohol and water as a crystallization solvent. The ratios of water:Iopamidol from 1:10 to 1:1 (v/w) and alcohol:Iopamidol from 1:1 to 1:10 (v/w) allow Iopamidol to be c...
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WO/2000/017150 |
Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as antihypercholesterolemic agents. The majority of them are produced by fermentat...
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WO/2000/016872 |
A method and system (10) for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a superco...
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WO/2000/014043 |
A method for recovering substantially pure 2,4,6-tri-(tert-butyl)phenol from a mixture comprising alkylated phenols by subjecting the mixture to melt crystallization. In a preferred embodiment, the method is conducted in the absence of a...
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WO/2000/012589 |
The present invention relates to a method for the production of small spherical particles consisting totally or partly of at least one water-insoluble linear polysaccharide by dissolving the at least one water-insoluble polysaccharide in...
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