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WO/2002/060584 |
Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures...
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WO/2002/057744 |
A first system of microfabricated components (104) includes at least a reservoir and a channel, and a second system of detection components (184) including at least a lens (190). The lens is focused on a sensing platform of the first sys...
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WO/2002/057798 |
A device (10) for processing a biological sample includes a processing unit (12) having at least one opening (14) to receive a sample vessel (16) and a plurality of processing stations (18) positioned along the opening (14). The processi...
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WO/2002/057488 |
The amount in which a probe is immobilized on an electrode can be determined quantitatively, making it possible to quantitatively detect genes with high sensitivity and enhanced throughput. A gene detection method whereby a gene having a...
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WO/2002/047807 |
The present invention is directed to methods and corresponding apparatuses for the continuous processing of organic materials. More specifically, the invention provides methods and apparatuses in which processing steps are performed usin...
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WO/2002/046361 |
Provided for heating cultured cells is a controlled heater device (20) comprising a cell culture apparatus (24), a transparent heater (28) in thermal contact with the cell culture apparatus (24), and may further comprise one or more of a...
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WO/2002/046719 |
The invention relates to a cryopreservation method, according to which at least one sample is placed on a storage substrate, and position-specific sample data that characterizes attributes of the sample is stored. The invention also rela...
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WO/2002/043615 |
A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending alon...
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WO/2002/043864 |
The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allo...
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WO/2002/044713 |
The present invention provides flow through devices for incubation and/or hybridisation on two-dimensional solid supports. In a first device the following parts are provided: a. a solid support comprising a target for binding; b. a suppo...
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WO/2002/041999 |
To counteract condense dew on a transparent cover film (3) covering each well (2) in an array of wells which forms a test plate (1) having a lower side formed by the bottoms of the wells (2) and an upper side formed by the upper edges of...
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WO/2002/041998 |
An apparatus for performing temperature cycling, comprising a micro channel reactor structure (46, 48, 50), and having a heating structure (b1, b2, B1, B2) defining a desired temperature profile. A preferred embodiment of a heating eleme...
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WO/2002/041997 |
A method of controlled heating of a micro channel reactor structure (46, 48, 50) comprises providing a structure (b1, b2, B1, B2) defining a desired temperature profile. A preferred embodiment of a heating element structure comprises a p...
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WO/2002/040158 |
A reaction plate (10) comprising a welded plastics planar laminate consisting of an aperture plate (12) and a film (22), the aperture plate (12) having at least one planar surface and a plurality of apertures (14) in the planar surface o...
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WO/2002/038809 |
The present invention refers to methods and devices for the detection of polymorphisms in a nucleic acid sample (e.g. blood, sperm, saliva, cells, ...). To enhance the efficiency and the reliability of the known methods (e.g. DGGE, SSCP ...
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WO/2002/031187 |
The invention relates to a device for hybridizing double-stranded DNA samples on oligomer arrays. The inventive device is comprised of a hybridization chamber, whose temperature can be controlled, and of at least one denaturation vessel,...
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WO/2002/031483 |
The present invention relates to a method for screening of polycondensation catalysts, wherein at least two polycondensation catalysis reactions are preformed simultaneously under substantially equivalent conditions in at least two react...
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WO/2002/029397 |
A polymer-based microfluidic device and its manufacturing methods. This microfluidic device is suitable for chromatographic and electrophoretic separations in which the detection of the components in the fluid is by means of ultraviolet ...
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WO/2002/026375 |
A CHTS reactor plate (10, 40) has wells (14, 44) that can be individually heated. The reactor plate (10, 40) includes a substrate (16, 46) with an array (12) of reaction wells (14, 44) and a ferromagnetic material (28, 58) included with ...
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WO/2002/024322 |
A microfluidic device having integrated components for conducting chemical operations. Depending upon the desired application, the components for manipulating charged entities, heaters, electrochemical detectors, sensors for temperature,...
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WO/2002/024336 |
A device for carrying out the parallel incubation of solutions comprises a holding frame (1) inside of which one or more titer plates (2) can be placed. Each titer plate (2) is separately closed by a cover plate (4), which can be pressed...
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WO/2002/022265 |
A microfabricated reaction chamber system for carrying out a nucleic acid sequence amplifiation and detection process on a nucleic acid sample, the process comprising at least first and second process steps using first and second reagent...
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WO/2002/022878 |
Microfluidic devices with improved channel and reservoir configurations are provided. More specifically, efficient microfluidic devices for the performance of temperature mediated reactions are provided. These reactions can be performed ...
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WO/2002/020161 |
A thermal cycling device consisting of a plate (99) having a plurality of wells for holding liquid samples (95) and a lid (10) for covering the plate (99). The lid includes a plurality of pins (18) which are inserted into or near the sam...
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WO/2002/016546 |
A thermal cycling device (12) for a titration plate (19) enables selected sample wells (18) to be individually subjected to heating and cooling cycles independent of the temperature of adjacent sample wells. Each sample well is fitted wi...
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WO/2002/016544 |
Disclosed is a thermal cycler (1).The Thermal cycler (1) comprises a polymerase chain reaction (PCR) module (10) having a plurality of receiving grooves for receiving a plurality of microplates (12) in which biological or chemical sample...
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WO/2002/013960 |
The invention relates to a nucleic acid library or protein or peptide library in the form of a two-dimensionally resolved grid-type arrangement with a plurality of grid elements. Every grid element contains, on the statistical average, a...
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WO/2002/011886 |
The invention relates to apparatus for diagnostic, experimental and other laboratory procedures and methods associated therewith. In particular, the invention provides a sample container for a fluid sample comprising a support, a recepta...
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WO/2002/009868 |
A novel apparatus (100) for generating temperature gradients is described. The apparatus includes a semiconductive wafer (110) and electrical connectors (114a, 114b) attached to, preferably, one of the edges of the wafer. Methods for tra...
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WO/2002/009867 |
The present invention relates to an arrangement, in particular for the parallel testing of a plurality of building blocks of a material library for performance characteristics, in which the arrangement has a block containing at least one...
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WO/2002/009877 |
The invention concerns a device for amplifying target nucleic acid sequences, reaction cartridges for use in said device, and modes for operating said device.
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WO/2002/002736 |
A reaction vessel requiring no centrifugal force when storing a reaction liquid into a reaction chamber, and capable of quickly controlling the temperature of a reaction liquid stored in a reaction chamber and expediting a reaction even ...
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WO/2002/002794 |
This invention relates generally to the field of microarray technology. In particular, the invention provides an integrated macroarray device, which device comprises a substrate comprising a plurality of distinct microlocations and a plu...
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WO/2002/001181 |
Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample material...
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WO/2002/001180 |
Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group pf process chamb...
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WO/2002/001919 |
A dissolution testing system comprises a vessel plate on which a plurality of vessels are mounted. Each vessel including a lateral wall having an outer surface around which a plurality of flexible heater elements are attached. Each heate...
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WO/2002/000347 |
Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is in the form of a disk, rotated during heating of the sample materials. The temp...
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WO/2001/097974 |
Microfluidic devices include venting channels (206, 208) which may be disposed surrounding a fluid-containing channel (202) to minimize the effects of bond voids.
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WO/2001/092460 |
Apparatus for examining a sample by microscopy, spectroscopy or crystallography under controlled environmental conditions. The apparatus comprises a sample chamber (1) which is fed by a gas stream (19) having a known vapour content, whic...
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WO/2001/089695 |
A valve for use in laminated plastic microfluidic structures. The valve allows one-way flow through microfluidic channels for use in mixing, dilution, particulate suspension and other techniques necessary for flow control in analytical d...
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WO/2001/089705 |
A system and method for manipulating magnetically responsive particles in a solution to separate nucleic acid molecules from cell components in a cell solution. The system and method employ a device capable of receiving a plurality of tu...
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WO/2001/088204 |
A method and system are disclosed for manipulating the flow of gases into and out of a microfluidic circuit (40) to regulate pressure within the circuit or to provide for the delivery of gases to or removal of gases from the circuit (40)...
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WO/2001/087487 |
This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention particularly provides microsystem platforms for achieving efficient mixing of one or a plurality of fl...
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WO/2001/084463 |
The invention provides an apparatus, method, and computer program product for determining a threshold value (e.g., a cycle number or time value) in a nucleic acid amplification reaction. The apparatus is programmed to amplify a nucleic a...
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WO/2001/081619 |
The invention is based on the concept of using the change in conductivity to be measured during the PCR as a marker for the progression of the PCR and for the quantification of the starting quantity of DNA. This apparatus determines the ...
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WO/2001/077045 |
The present invention provides a method/device (1) for enhancing a chemical reaction including PCR and ELISA by utilizing electromagnetic or mechanical energy. Such method/device (1) can also be used for increasing the rate at which a gr...
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WO/2001/075415 |
A device for promoting protein crystal growth (PCG) using microfluidic channels. A protein sample and a solvent solution are combined within a microfluidic channel having laminar flow characteristics which forms diffusion zones, providin...
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WO/2001/073417 |
Analytical systems and methods that use a modular interface structure (600) for providing an interface between a sample substrate (630) and an analytical unit (610) where the analytical unit (610) has a particular interface arrangement f...
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WO/2001/072424 |
A method and apparatus for heating specimens in wells of a metallic specimen carrier. The specimen carrier is heated by applying resistive heating directly to the carrier. An AC source and transformer may be used where the specimen carri...
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WO/2001/070399 |
The invention relates to a test chamber (100), for fluid treatment of at least one sample, comprising a construction of a support plate (10), for a first test arrangement (11) and a cover plate (20), for covering the first test arrangeme...
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