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WO/2003/019164A1 |
Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer, etc.) of analytes, e.g., biomolecules, with respect to analyte-containing solutions using on...
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WO/2003/015901A1 |
A method of separating components having a given negative or positive charge and contained in a sample is disclosed. The method involves, in one embodiment, loading a microchannel with a sample, placed between a trailing- edge electrolyt...
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WO/2003/014739A1 |
A method whereby first biological entities are recognized by way of second biological entities able to bind to the first (or the first to the second), including the steps of binding first biological entities to a surface comprising an ar...
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WO/2003/008074A1 |
Buffer compositions with or without sieving formulations are useful when used in connection with a capillary electrophoresis systeem as shown in Figure. The buffer composition can include Bis-Tris, TAPS and/or TAPSO and optionally a chel...
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WO/2003/001193A1 |
A continuous-flow filter/concentrator for separating and/or concentrating particles in a fluid is disclosed. The filter/concentrator comprises three ports: an inlet port (110), an filter port (170) and a concentrate port (200); a plurali...
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WO/2002/098554A1 |
Devices with electrokinetic elements are disclosed as well as their method of microfabrication for use in micro-scale analysis, mixture separation and reaction. The devices consist of solid hydrophilic-matrix films (2) that have been mic...
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WO/2002/092200A1 |
Methods and apparatus that are embodied in Figure 2 are presented that facilitate electrophoresis of prior-cast, hydratable separation media, usefully immobilized pH gradient (IPG) strips: The method exploits the swelling of rehydration ...
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WO/2002/092199A1 |
The activity of encogenic intercellular chemical reactions of molecules is measured by the use of fluorescently labeled substrate molecules that underdo a change in electrophoretic mobility upon a chemical reaction such as that catalyzed...
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WO2002076586B1 |
A precast slab gel for use in submerged horizontal electrophoresis is formed in a tray situated so that it does not move or float during use. Easily removable tabs are designed to mate with grooves present in the tank and since the tabs ...
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WO/2002/088300A1 |
The invention concerns the use of a miniature device for separating and isolating biological objects for various applications in the field of molecular biology, methods for making DNA or protein chips in particular, and the DNA or protei...
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WO/2002/088321A2 |
Embodiments of a device (10) and method are described which provide for concentration and purification of analytes, e.g. polynucleotides, in channel devices using AC and DC electric fields. The device comprises a substrate (12), channels...
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WO/2002/083571A1 |
A water treatment method and a water treatment apparatus capable of remarkably improving the effect of removing the bacteria from drinking water or drainage, and a water culture system using the method and the apparatus. The water treatm...
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WO2001053819A9 |
A microfabricated silicon chip with a separation material, such as in situ prepared porous polymer monoliths (254) in its microchannels is disclosed. The polymer monoliths are liquid-permeable and serve as microcolumns for liquid chromat...
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WO/2002/079097A1 |
The present invention relates to a method and apparatus for the removal of ions from a fluid. The method comprises contacting the fluid with a charged particulate material such that at least a portion of the designated ions are electrost...
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WO/2002/076585A1 |
A method and apparatus for fractionation of a mixture of particles and for particle analysis are provided, in which LEAPS ('Light-controlled Electrokinetic Assembly of Particles near Surfaces') is used to fractionate and analyze a plural...
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WO/2002/077269A1 |
This invention relates generally to the field of cell separation or isolation. In particular, the invention provides a method for separating cells, which method comprises: a) selectively staining cells to be separated with a dye so that ...
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WO/2002/077259A2 |
The present invention recognizes that the determination of ion transport function or property using direct detection methods, such as patch-clamps, whole cell recording or single channel recording, are preferable to methods that utilize ...
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WO/2002/075276A2 |
An adaptive alignment technique provides precise control and active positioning in two-dimensions of sub-millimeter-sized objects such as, a spherical microlens (1) through the application of electrophoretic forces in a microfluidic well...
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WO/2002/070816A2 |
Methods and devices are provided for treating a fluid with a high voltage electric field for decontaminating the fluid or a variety of other purposes. In a preferred embodiment for decontamination, the method includes (a) applying an ele...
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WO2001043880A9 |
The invention relates to a device (1) for continuous separation of a desired fraction of particulate matter from a liquid suspension containing such particulate matter, the device (1) comprising electrode elements (2, 3) and means for ge...
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WO/2002/059598A1 |
A micropositioner is disclosed including a carrier with a small diameter channel and electrodes for generating an electrical field. A fluid compartment containing cells surrounds one side of the channel and the voltage of the electrical ...
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WO/2002/059589A2 |
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir. The cartridge supports, for example, mu...
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WO/2002/050524A2 |
The invention relates to a free flow electrophoresis method for separating sample substances into their analytes. Said method comprises several steps; a first step for the crude fractionation of the sample substance and at least one seco...
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WO/2002/051115A1 |
The invention relates to an electrophoresis device comprising a separation chamber that is provided with at least one sample inlet on the inlet side and outlets (9) for the electrophoretically treated sample species on the outlet side. T...
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WO/2002/043870A1 |
The invention relates to a fluidic microsystem (100) comprising at least one compartment (10) for the admission and/or passage of a liquid and an electrode assembly (20) containing a large number of electrodes (21-28), between which an i...
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WO2001036073A9 |
A method and device is disclosed for rapidly identifying a large number of proteins by placing a protein mixture (15) in a sample chamber (22) of an electrophoresis gel (12), and performing electrophoresis to separate the mixture (15) by...
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WO/2002/038262A1 |
The invention relates to a method for generating a convective liquid motion in a fluidic microsystem (100). According to this method, a liquid in a microsystem is simultaneously exposed to an electrical field and a thermal gradient. The ...
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WO/2002/036245A1 |
The present invention provides the use of membrane-based electrophoresis in combination with one or more conventional separation techniques to obtain a desired compound from a mixture of compounds. the use of one or more membrane-based e...
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WO/2002/037091A1 |
Methods of concentrating materials within microfluidic channel networks by moving materials into regions in which overall velocities of the material are reduced, resulting in stacking of the material within those reduced velocity regions...
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WO/2002/031506A1 |
The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable, nondisruptive, and automatable method for ...
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WO/2002/029397A2 |
A polymer-based microfluidic device and its manufacturing methods. This microfluidic device is suitable for chromatographic and electrophoretic separations in which the detection of the components in the fluid is by means of ultraviolet ...
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WO/2002/028516A1 |
Multi-port electrophoresis apparatus comprising: (a) cathode chamber with inlet and outlet means defining an anolyte flow path; (b) anode chamber with inlet and outlet means defining an anolyte flow path, to generate an electric field; (...
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WO2000047322A9 |
A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor....
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WO/2002/028523A2 |
This invention relates generally to the field of moiety or molecule manipulation, e.g., in a chip format. In particular, the invention provides a chip for generating fields, which chip comprises: a) a substrate; and b) at least two diffe...
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WO/2002/027909A2 |
A device (103, 106, 112, 113, 110, 152, 158, 168, 170A, 170B, 170C, 182, 184, 250, 295) acts as a particle switch to transport and/or re-direct microparticles which are in a fluid suspension. The switch (103, 107, 112, 113, 110, 152, 158...
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WO/2002/024314A1 |
An electrophoresis apparatus comprising a separation unit with a first electrolyte chamber and a second electrolyte chamber, a first sample chamber and a second sample chamber, a first ion permeable barrier positioned between the first s...
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WO/2002/025264A1 |
An electrophoresis separation material, especially for isoelectric focusing, comprising a carrier material to which pH-buffering groups are firmly attached and anode side and cathode sides. At least a first portion of the pH-buffering gr...
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WO/2002/024313A2 |
The invention provides compositions, methods and kits for high speed, high resolution of analytes by capillary electrophoresis starting with uncoated capillaries. The compositions comprise a sieving component, comprising a non-crosslinke...
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WO/2002/021116A2 |
Electrophoresis is performed simultaneously in a multitude of slab gels in a single cell that supports the slab gels vertically and parallel to each other while immersed in a buffer solution, and that applies a voltage to all gels simult...
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WO/2002/018901A2 |
The present invention includes apparatus (10) for simultaneous loading of multiple samples for molecular separation, including a separation area (11) with walls (12, 14, 16) wherein at least one of the walls has apertures (38) having loa...
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WO/2002/018929A2 |
Separation devices and systems are described which have a stationary phase and a mobile phase, wherein the stationary phase contains carbonaceous material having attached at least one organic group. The stationary phase which is used in ...
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WO2001085305B1 |
A solid-liquid mixture is electro-dewatered by apparatus having a conveyor belt for receiving an electric charge and having the mixture deposited thereon and an element above the conveyor belt receiving an opposite electric charge with t...
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WO/2002/004656A2 |
The invention relates to the application of bio-probes which bind specifically to biological material and thus permit the detection and/or separation of the material so marked from an environment of similar biological material, by means ...
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WO/2002/000937A1 |
A composition of matter utilizes the pre-polarized DNA (sodium salt for chemical stability) of a predetermined animate entity operating as the dielectric replicate matching reference material. The pre-polarized DNA is in an electret stat...
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WO/2001/096023A2 |
An engineered microparticle and methods and systems relating thereto. The microparticle includes a conductive core and an insulating layer surrounding the conductive core and having a thickness sufficient to render the microparticle resp...
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WO/2001/096025A2 |
Systems, apparatuses and methods for cell isolation and analysis. Cells are introduced into a dielectrophoretic prefilter including one or more trapping electrodes configured to trap at least a portion of the cells with a dielectrophoret...
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WO/2001/096024A2 |
Methods and apparatuses for metered injection of a fluid packet. A vessel containing the packet is pressurized to a pressure less than or equal to a hold-off pressure. The packet is subjected to an extraction force to extract the packet ...
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WO/2001/096857A2 |
Methods and apparatuses for discriminating matter utilizing dielectrophoresis combined with magnetophoresis. A sample having one or more constituents is injected into an inlet port of a chamber. A carrier medium flow is initiated at the ...
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WO/2001/083113A1 |
A method and apparatus for analysing very low concentrations of particles present in a fluid sample. The apparatus comprises a support (1) defining a fluid flow channel (9) and a dual electrode array comprising a first electrode means (2...
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WO/2001/081910A1 |
Parallel plate slab gel enclosures (slab gel cassettes) used for vertical slab gel electrophoresis are secured to a frame (14) to form a chamber for an upper buffer solution, and the securement is achieved by a pair of clamps (16, 17) th...
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