Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 551 - 600 out of 4,263

Document Document Title
WO/1994/000408A1
A high performance chiral selector having formula (I) whereinAr is a monocyclic or ortho-fused polycyclic aromatic moiety having up to 10 ring carbon atoms, either of which may be unsubstituted or substituted with one or more C1 to C6 al...  
WO/1994/000455A1
The present invention relates to a composition having general formula (I), wherein each of A, B, C, X, Y, and Z is independently O, NH, N(CH2)mCH3, N(C=O)(CH2)mCH3, CH2, S, or Se; each of R1, R2, and R3 is indepently phenyl, 4-hydroxyphe...  
WO/1993/023394A1
The object of the present invention is a process for producing optically pure S-timolol or its derivatives wherein racemic R,S-timolol, or its racemic derivative, at elevated pressure and dissolved in carbon dioxide is periodically fed t...  
WO/1993/022269A1
3(S)-methylheptanoic acid is prepared by fractional crystallization of the salt of racemic 3-methylheptanoic acid with (S)-alpha-methylbenzyl amine followed by acidification.  
WO/1993/021176A1
Novel cyclic amino acids which are useful in preparing biologically active peptides as well as a process for the preparation of D and L enantiomers of the cyclic amino acids are described where an N-protected derivative of the racemic cy...  
WO/1993/020052A1
(S)-$g(a)-phenyl-2-pyridineethanamine, and its pharmaceutically acceptable derivatives, are useful in the treatment of neurodegenerative disorders, and exhibit linear pharmacokinetics.  
WO/1993/017022A1
The (6S_) stereoisomer of folinic acid is obtained in high optical purity by salification of (R, S) folinic acid with di- or polyamines and subsequent selective crystallization of the desired diastereomeric salt.  
WO/1993/017055A1
Polymer particles having a hydrophobic core and various surface functional groups, particularly hydrophilic and chiral surface functional groups, are produced by adding a non-emulsified functional polymerizable monomer to the aqueous pha...  
WO/1993/016035A1
The method proposed for separating racemates of verapamil is characterized in that the free base of the compound is reacted with optically active dibenzoyltartaric acid or ditoluoyltartaric acid in the molar ratio 1:1 to 1:2 in a mixture...  
WO/1993/016074A1
A novel isoindolinone derivative of formula (I) in racemic form or in the form of its enantiomers; preparation thereof; and pharmaceutical compositions containing same. The novel product of formula (I) is useful in therapeutics as an anx...  
WO1993013053A3  
WO/1993/015039A1
A process for the separation of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. In this process: i) a solid racemic mixture of an aliphatic carboxylic acid or ester thereof having formula (I), wher...  
WO/1993/015037A1
An improved process for the separation of enantiomers of a mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process involves adding in inert liquid to the reaction solution formed by: (i) forming a salt s...  
WO/1993/015038A1
An improved process for the separation of enantiomers of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process involves adding a mixture of the aliphatic carboxylic acid to the material forme...  
WO/1993/015040A1
An improved process for the separation of enantiomers of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process involves: (i) forming a salt solution comprising said racemic mixture of a C1 to...  
WO/1993/014056A1
A process is disclosed that is useful for separating the enantiomers of a racemic mixture of an aliphatic carboxylic acid having formula (I), where R1 is hydrogen or alkyl, R2, R3 and R4 are independently different and are hydrogen, alky...  
WO/1993/013087A1
A process for the resolution of (+-)-alpha-[2-[acetyl(1-methylethyl)amino]ethyl]-alpha-(2-ch lorophenyl)-1-piperidinebutanamide having structure (I) into its (+) and (-) enantiomers using camphorsulfonic acid.  
WO/1993/013053A2
A process for obtaining an isomer of a compound of the general formula (I): R-CH(CN)-R', wherein each of R and R' may be any organic radical linked directly or through a heteroatom to the carbon atom bearing the cyano group provided that...  
WO/1993/013034A1
A process for separating a selected amino acid (enantiomer) from a mixture of different compounds including other amino acids is disclosed, in which process the mixture is contacted with a polymer material which is composed of cross-link...  
WO/1993/012054A1
This invention relates to certain salts of leukotriene antagonists and the use of a particular amine to form these salts as a means for selectively crystallizing optical isomers of the leukotriene antagonists disclosed herein.  
WO/1993/012062A1
A novel multi-step process for preparing the (4S_-enantiomer of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone in a highly-optically pure form is disclosed. The process involves (1) first esterifying 4-(3,4-dichlorophenyl)-4-keto...  
WO/1993/010118A1
Described is a method of preparing (6S)-5-methyl-tetrahydrofolic acid by separation of the racemic mixture, (6R,S)-5-methyl-tetrahydrofolic acid, using a base, characterized in that N-ethyl-2-aminomethylpyrrolidine or one of its optical ...  
WO/1993/008903A1
A process is disclosed for separating enantiomers by an electrokinetic process in capillary columns, using surface-immobilized chiral components. The chiral component used may be a polysiloxane to which alkylated cyclodextrine (alpha, be...  
WO/1993/009075A1
A method for separating enantiomers of derivatives of aryloxipropanolamines is disclosed. In the method, the derivative is contacted with a chiral solid-phase chromatography material containing molecular imprints of an optically pure ena...  
WO/1993/008162A1
The present invention is directed to a compound of formula (I), wherein R represents a hydrogen atom or an acyl, aroyl or cycloalkylcarbonyl radical or a residue of formula (Ia); R1 represents an alkyl radical; R2 represents an aryl or h...  
WO/1993/007135A1
3-(N-isopropyl-N-n-propylamino)-5-(N-isopropyl)carbamoylchro man having formula (I), as racemate, (R)-enantiomer in the form of free base or pharmaceutically acceptable salts thereof. The object of the present invention is to provide com...  
WO/1993/007104A1
A carrier and a column for high-performance liquid chromatography having an ability to separate optical isomers. A separating agent for optical isomers is prepared by chemically bonding conalbumin to a carrier such as silica gel or synth...  
WO/1993/006080A1
The invention relates to a chiral selector useful in separating underivatized enantiomers of non-steroidal anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such s...  
WO/1993/005004A1
A compound represented by general formula (I) and a separating agent comprising the same. In formula (I), Ar and Ar' represent each an aromatic group and two substituents on the central benzene ring may be positioned ortho, meta or para ...  
WO/1993/004022A1
A method of recovering and reusing a solvent and an optical isomer, characterized by providing a packed bed, which is disposed in the passage for circulating a solvent and packed with a packing material for optical resolution, with a por...  
WO1993000330A3  
WO/1993/002079A1
Optically pure thiazolidinedione alcohols and ethers, and synthetic intermediates for preparing said alcohols and ethers. These compounds have utility as hypoglycemic and hypocholesterolemic agents.  
WO/1993/001190A1
A novel 2-amino naphthyridine derivative having formula (I), optical isomers and salts thereof, and its preparation. The product of formula (I) is particularly useful for preparing the eutomer of the product of formula (II), which has re...  
WO/1993/001156A1
A process for obtaining a substantially pure enantiomer of ibuprofen is described. The process utilizes first an enantiomerically enriched mixture of ibuprofen obtained from kinetic resolution, diastereomeric crystallization or asymmetri...  
WO/1993/001167A1
Compounds of formule (I), salts thereof, the preparation thereof, and drugs containing same.  
WO/1993/000330A2
The present invention relates to novel azanorbornane derivatives having formula (I), wherein R1 through R12 are as defined in the description, and to novel intermediates used in their synthesis. The compounds having formula (I) are usefu...  
WO/1992/020334A1
The use of S(-)sodium 2-(4-isobutylphenyl)propionate (the sodium salt of S(+)-ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-iso...  
WO/1992/019684A1
Pyridone dyes of formula (I), wherein R?1� stands for hydrogen or C�1?-C�4? alkyl, R?2� and R?3� may be identical or different and independently stand for hydrogen, optionally substituted C�1?-C�12? alkyl, C�5?-C�7? cyc...  
WO/1992/018455A1
A method for resolving (+)-/alpha/-(3-benzoylphenyl)propionic acid is disclosed. The method comprises: (i) converting said propionic acid with (-)-cinchonidine in a solvent comprising a mixture of an aliphatic ester and an alkyl alcohol;...  
WO/1992/016536A1
New racemic, optically active phosphorous compounds have the formula (I), in which R stands for lower alkyl, lower alkoxy or a protected hydroxy group; R1 stands for a 5-membered heteroaromatic compound; R2 stands for lower alkyl or lowe...  
WO/1992/016274A1
In a continuously operated counter-current chromatography process, relative displacement between the adsorber, composed of a solid phase, and a liquid movable phase, in successively linked chromatography columns, is obtained by successiv...  
WO/1992/015617A1
A novel polysaccharide derivative prepared by replacing part or the whole of the hydroxyl or amino groups of a polysaccharide by two or more different substituents, and a separating agent and a separator both containing this derivative. ...  
WO/1992/015616A1
A compound prepared by chemically bonding at least one hydroxyl group of the 2-, 3- and 6-hydroxyl groups of a cyclic oligosaccharide derivative to a carrier through a spacer (except one wherein the 6-hydroxyl group is bonded to a carrie...  
WO/1992/013872A1
Compounds of general formula (I) in the form of a 22R and 22S epimer, wherein X1 and X2 are the same or different and each represents a hydrogen atom or a fluorine atom, provided that X1 and X2 are not simultaneously a hydrogen atom, pro...  
WO/1992/013823A1
A compound of formula (I), or a salt or solvate thereof, in which R1 and R2 each independently represents hydrogen, alkyl, optionally substituted aryl or optionally substituted aralkyl; R3 represents alkyl, optionally substituted aryl or...  
WO/1992/012152A1
Azabicyclo[2.2.2]octan-3-imines of general formula (I), wherein R1, R2 and R3 are as defined herein are prepared by reacting a compound of formula (II) with a compound of formula (III), wherein A is MgCl, MgBr or Li.  
WO/1992/012180A1
Novel cyclodextrin and epichlorohydrin based polymers are obtained by adding an epoxy-ammonium salt to a cyclodextrin-epichlorohydrin polycondensate wherein the ratio of cyclodextrin to epichlorohydrin is 1:3 to 1:10 and the proportion o...  
WO/1992/012135A1
Optically substantially pure (-) enantiomer of [[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl] hydrazono]propanedinitrile or pharmaceutically acceptable salt thereof, intermediates and a process for the preparation are descr...  
WO/1992/008702A1
A method for resolving chiral hydantoins having general formula (I), wherein R1 is a lower alkyl radical having 1-5 carbon atoms in a linear or branched chain; and R2 is a phenyl radical which is optionally mono-, di- or trisubstituted b...  
WO/1992/005151A1
This invention relates to salts of formula (I) where, A is 1 and X is 1 or 2; R1 is C8 to C13 alkyl, C7 to C12 alkoxy, C7 to C12 alkylthio, C10 to C12 1-alkynyl, 10-undecynyloxy, 11-dodecynyl, phenyl-C4 to C10 alkyl, phenyl-C3 to C9 alko...  

Matches 551 - 600 out of 4,263