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JPWO2015064453A1 |
the present invention has a thiol group in a side chain -- optics -- it made into a subject to provide a method of manufacturing active D* object and/or L* object amino acid with sufficient yield by a simple method. The present invention...
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JP6086512B2 |
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JP6087504B2 |
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JPWO2014157607A1 |
optics useful as a manufacturing raw material of medicine, agricultural chemicals, and an industrial commodity -- the optical purity improving method of active 2* hydroxycarboxylic acid is provided. Hydroxycarboxylic acid denoted by the ...
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JPWO2014148344A1 |
The present invention is a manufacturing method of optical activity transformer 1, optical activity transformer 1 which makes it Crystallization from solution of 2* Diamino cyclohexane, and obtains a crystal of optical activity transform...
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JPWO2014125667A1 |
The present invention provides an optical isomer separating medium and a manufacturing method for the same. That is, the present invention is following formula (I) : Each sign in [type is as given in a specification. A spiral poly (diphe...
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JPWO2014119731A1 |
By non- A conversion reaction of L* isoleucine, a method of manufacturing D* alloisoleucine by a short process and quantity yield is provided. To the specific system of reaction in the state where L* isoleucine and D* alloisoleucine Epim...
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JP2017502020A |
Formula (1) [Formula 1] It is Of compound and they are inside of a formula, and R.1A Is hydrogen , Halo , C1*C4 Alkyl machine, C1*C4 Alkyl halide machine, and C1*C4 alkoxy *C2*C4 Alkyl machine, C2*C4 alkenyl group, C2*C4 alkynyl group, o...
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JP2016539924A |
Formula (I) [Formula 1] (The inside of a formula, X, R)1*R7It has a meaning defined as a The book specification. HBV replication inhibitor which is of HBV replication inhibitor and contains the stereochemical opposite-sex form, salt, a h...
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JP6045531B2 |
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JP6023794B2 |
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JP2016164191A |
To provide a method for producing a high-quality optically active thiazolylalanine derivative and salt thereof, in which the method does not require the use of any unsafe reagent and is economically advantageous, and is suitable for the ...
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JP5986380B2 |
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JP2016155849A |
To provide methods for producing substituted heterocycle fused gamma-carbolines, intermediates useful in producing them, methods for producing such intermediates and such heterocycle fused gamma-carbolines.The invention provides compound...
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JP5981719B2 |
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JP5968439B2 |
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JP5951825B2 |
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JP2016065046A |
To provide an industrial method for producing (2S,12Z)-2-acetoxy-12-heptadecene which is a sexual pheromone of pistachio twig borer.The present invention can provide a production method and the like including at least the steps of: react...
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JP2016065024A |
To provide a method for optical resolution of carboxylic acid.Provided is a method for optical resolution of carboxylic acid in which (S)-3-cyclohexene-1-carboxylic acid represented by the chemical structure of the left side in formula (...
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JP5901292B2 |
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JP2015505827A5 |
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JP2016040282A |
To provide methods for production of cyclopropyl ring-fused pyrrolidine compounds of dipeptidyl peptidase IV inhibitors.The present invention provides a method for production of a free base compound represented by formula M'.SELECTED DRA...
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JP5888993B2 |
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JP2014525895A5 |
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JPWO2013154066A |
a subject of the present invention -- optics -- it is manufacturing an active bicyclic compound efficiently. enzyme -- optics -- an active bicyclic compound is manufactured efficiently.
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JP2014530809A5 |
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JP2015526384A |
[Subject] Offer of a new manufacturing method of a stereoselective epoxy ketone compound. [Means for Solution] A manufacturing method of an epoxy ketone compound denoted by a formula (1) denoted by the following scheme. Thereby, an epoxy...
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JP2015129121A |
To provide a method for obtaining a dihydro-1,3,5-triazine amine derivative useful as a pharmaceutical composition in a high yield and high excess enantiomorph ratio.There is provided a method for separating an enantiomer of a dihydro-1,...
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JP5744076B2 |
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JP5743595B2 |
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JP5738204B2 |
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JP5734533B2 |
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JP2015091886A |
To provide an alternative preparation method for amino acid derivatives.An improved method of producing lacosamide (LCM), or (R)-2-acetamido-N-benzyl-3-methoxypropion-amide, useful as an anticonvulsant agent is provided. In a specific em...
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JP5714213B2 |
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JPWO2013089188A |
carrying out optical division using optical activity amine -- optics -- an active bicyclic compound is manufactured efficiently.
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JP2015509496A |
It is provided for this specification, The unusually high level, the disease related as it is active, or state of TNF-alpha is treated or prevented. It is a new preparing method of the amino sulfone intermediate for composition of useful...
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JP2015048332A |
To provide a compound for optical resolution capable of easily optically resolving the optical isomer mixture of amino acid at high sensitivity, and an optically resolving method using the compound.Provided is a compound for optical reso...
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JP2013528577A5 |
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JP2015505827A |
The present invention provides (*) *2* exo* morpholino iso ボルン *10* チオール and an efficient and economical synthesizing method of the chiral catalyst エナンチオマー (ed) and related. A new molecular entity and an asymm...
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JP2015027979A |
To provide a novel optically active α-aminophosphonate derivative, and an efficient method of manufacturing the same.A compound of the general formula (1) is obtained by reacting thionophosphonoyl ketimine and phosphite diester by using...
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JP2015504054A |
The present invention provides medical treatment of multiple sclerosis of medical treatment of multiple sclerosis which contains the phenyl carbamate compound as a part for a phenyl carbamate compound and validity and/or a pharmacy const...
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JP5663154B2 |
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JP5662345B2 |
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JP5656635B2 |
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JP2014516920A5 |
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JP2015003861A |
To easily and efficiently produce (R)-2-amino-2-ethylhexanol that is useful as a pharmaceutical intermediate without carrying out a complicated operation.(R)-2-amino-2-ethylhexanol is produced by subjecting a N-benzylidene-2-amino ester ...
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JP5646606B2 |
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JP2014503480A5 |
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JP2014527534A |
The present invention relates to spiro Ben Jill Amin * phosphine, a manufacturing method for the same, and its use. It is a compound which has the structure denoted by formula (I), is here, and is n=0*3;R.1R2R3R4R5R6R7R8R9A の value is ...
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JP5605008B2 |
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