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Patent Searching and Data


Matches 801 - 850 out of 4,328

Document Document Title
JP5514549B2  
JP5503546B2  
JP2014088389A
To provide a diagnostic agent for positron emission tomography, comprising a [F-18]-labeled compound.A diagnostic agent for positron emission tomography (PET) comprises a compound which is a L-glutamic acid or L-glutamic acid derivative ...  
JP5487440B2  
JP2014074033A
To provide methods for isolating from a reaction mixture a salt of a mono-propargylated aminoindane (rasagiline), which is a selective inhibitor of MAO-B and useful in treating Parkinson's disease etc.Disclosed are production methods for...  
JP5476859B2  
JP2014509592A
The present invention provides the compound of formula (I), this salt permitted as medicine, a prodrug, a biological activity metabolite, a stereoisomeric form, and an opposite-sex object, and the variable thing is defined in this specif...  
JP2014509304A
The present invention experiences the new method for manufacturing Sis *1* ammonium *4* alkoxy cyclohexane カルボ nitril salts, and the manufacturing method by the present invention, or relates to the new intermediate output or the st...  
JP5468003B2  
JP5456871B2  
JP5455394B2  
JP5452165B2  
JP5451870B2  
JP2014043463A
To provide alkanoylamino benzamide aniline HDAC inhibitor compounds.The present invention provides a compound of the general formula (I) having histone deacetylase (HDAC) inhibitory activity, a pharmaceutical composition comprising the c...  
JP5437525B1
[Subject] The present invention is melatonin MT.1In addition to a tyrosine derivative useful as a receptor antagonist, in a benzene ring of m* tyrosine, an iodine machine is introduced by good site selectivity and quantity 収率 at leas...  
JP5435656B2  
JP5436438B2  
JP5425806B2  
JP5424650B2  
JP2014031327A
To easily and efficiently produce an optically active cis-2-amino-cyclohexane carboxylic acid derivative that is important as a raw material of pharmaceutical products from an easily available starting material.An optically active cis-2-...  
JP5421311B2  
JP5422827B2  
JP5417560B2  
JP2014503480A
The present invention provides ジュウテリウム-ized ラサギリン, its salt, and use.  
JP5416928B2  
JP5410749B2  
JP5404655B2  
JP2014502270A
The present invention relates to the method of manufacturing compounds 1a and 1b of the pure following chemical formula 1 optically from the Rasse Mick compound 1 of the following chemical formula 1, respectively. [-izing 1]compounds 1a ...  
JP5404414B2  
JP5399711B2  
JP5398662B2  
JP2014012678A
To provide a novel compound that can be used as a selective mineralocorticoid receptor antagonist for treating disorders in particular cardiovascular disorders, and a medicament containing said compounds for the treatment and/or preventi...  
JP2014012713A
To provide a method of producing optically active trans-2,6-dimethylmorpholine.A method of producing optically active trans-2,6-dimethylmorpholine comprises steps of: (i) reacting racemic trans-2,6-dimethylmorpholine with D-mandelic acid...  
JP5395901B2  
JP2014005252A
To provide (R)-2-[(4,6-dimethoxypyrimidine-2-yl)hydroxymethyl]-6-methox ymethylaniline having a high herbicidal effect.This invention relates to (R)-2-[(4,6-dimethoxypyrimidine-2-yl)hydroxymethyl]-6-methox ymethylaniline or salts thereof...  
JP5387040B2  
JP5380743B2  
JP2013256526A
To provide an optically pure (-)-venlafaxine derivative and a synthesis process thereof; and a composition containing the derivative and usage thereof.Provided is a pharmaceutical composition consisting of a (-)-venlafaxine derivative es...  
JP2013544787A
Disclosed are methods, reagents, and intermediates useful for making azaindazole derivatives, which may be used to modulate Glucokinase. The disclosed methods and materials are generally useful for making halo-esters and sulfonyl-substit...  
JP5366192B2
The invention relates to a method for preparing enantiomerically pure 4-pyrrolidinophenylbenzyl ether derivatives of formula I: wherein R1, R21, R22, R23, R24 and n are as defined in the description and claims and to intermediates useful...  
JP2013241339A
To provide a method for producing an optically active amino acid simply and in good yield without necessitating a special facility.A method for producing an optically active amino acid simply and in good yield includes: making an amino a...  
JP2013241338A
To provide a method for producing an optically active 2-aminobutyric acid simply and in good yield without necessitating a special facility.A method for producing an optically active 2-aminobutyric acid includes: a step of heating 2-amin...  
JP5359348B2
To provide a method for purifying lactic acid from an aqueous lactic acid solution by a crystallization method without passing through a complicated operation, when producing the lactic acid having high purity and high optical purity, be...  
JP2013237675A
To provide a method for optical resolution of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile, and to provide a method for synthesis of ivabradine, of its addition salts with a pharmaceutically acceptable acid and of their hyd...  
JP5352478B2
A process for the enantioselective preparation of (2 R ,3 S )-3-phenylisoserine methyl ester acetate salt of formula (I) which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of ra...  
JP5328564B2
To provide a method for obtaining high-purity wine lactone abundantly containing natural wine lactone industrially and in a high yield by a simple method that does not need a dangerous reagent requiring a severe caution in handling, a he...  
JP5326400B2
Disclosed is a purification method of reducing and removing fluoride ions contained in an optically active ±-fluorocarboxylic acid ester represented by formula [1] [in the formula, R 1 represents a C 1-6 alkyl group, R 2 represents a C ...  
JPWO2012020724A
A manufacturing method of an amino アダマン tongue carbamate derivative useful as an important intermediate of 11betaHSD*1 inhibitor is provided. Formula (I) :(Inside of a formula, R)1And R2はそれぞれ independence is achieved, a...  
JP5322641B2
The present invention relates to a process for preparing optically active bisphosphinylalkanes from the correspondingly substituted, racemic 1,2-diols. The optically active bisphosphinylalkanes which can be obtained in this way are suita...  
JP5322928B2
The invention relates to a process for the manufacture of enantiomerically enriched or pure compounds of formula I wherein R1, R2, R3, R6, R7 and Q are defined as in claim 1 as well as their crystalline forms for the treatment of prolife...  

Matches 801 - 850 out of 4,328