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Matches 1,151 - 1,200 out of 4,296

Document Document Title
JP4481659B2  
JP2010520188A
A process for preparing a compound of formula (III) comprising condensing an oxiranyl compound of formula (I) with an amine of formula (II) or a salt thereof wherein: R1 is a group selected from alkyl, aryl, allyl, alkoxy, cycloalkyl, he...  
JP4474745B2  
JP2010519262A
A process for the enantioselective preparation of (2 R ,3 S )-3-phenylisoserine methyl ester acetate salt of formula (I) which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of ra...  
JP2010517972A
[Formula 1]the present invention -- formula: -- it is related with the synthesizing method and intermediate of the compound of (XVII), and its salt. [Chosen drawing] Nothing  
JPWO2008099730A1
本願は、工業的規模で簡便かつ安価に製造可 能な新規なアミン化合物の光学分割剤を提供 することを課題とする。この課題は、光学活 性な2−(アロイルオキシ)プロピオン...  
JP4469179B2  
JP2010106011A
To provide a method for producing optically active mandelic acids having high purity and useful as pharmaceutical and agrochemical raw materials, liquid crystal materials and optical resoluting agents.Crystals of objective optically acti...  
JP4461048B2  
JP2010513282A
The present invention provides crystalline out R (+) -N-propargyl 1-amino in, its medicine constituent, and a manufacturing method for the same. [Chosen drawing] Nothing  
JP2010513531A
The present invention indicates manufacture and the isolation method of each stereoisomeric form of 1* amino , 3* substitution phenyl cyclopentanecarboxylic acid ester.  
JP2010511711A
The present invention provides processes and intermediates for the preparation of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and salts thereof which are useful as serotonin-2C (5-HT2C) receptor agonists for the treatment o...  
JP4450399B2  
JP2010065032A
To provide a method for obtaining a synthesis intermediate of ivabradine useful in the treatment or protection of various pathological conditions and heart failure associated with supraventicular heart rate abnormalities in a manner in w...  
JP4437648B2  
JP4437012B2  
JP2010508240A
The present invention relates to a manufacturing method ofR [1] and (R [2]) *3* (3* dimethylamino *1* ethyl *2* methyl * propyl) * phenol.  
JP4434614B2  
JP2010507604A
The present invention indicates one step-by-step procedure for composition of 2* フルオロ propionate from the lactic acid ester derivative which uses TFEDMA.  
JP2010507574A
The present invention is a formula (1) (the inside of a formula and X are hydrogen and COR).11Or R13A table is carried out and it is R.13はC1*C6アルキル is expressed and it is R.1は, C1*C7アルキル, C3*C7アルケニル or C2*C7...  
JP2010053149A
To provide a purification method for a latanoprost and a high-purity latanoprost.The method for purifying the latanoprost is conducted by HPLC characterized by use of a mixture containing one ore more hydrocarbons, one or more alcohols, ...  
JP4425632B2  
JP2010504978A
3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions compris...  
JP4415543B2  
JP2010503393A
Present invention, The enantioselective acylation method of transformer *2* benzyloxy cyclohexylamine or Sis *2* benzyloxy cyclohexylamine of making the エナンチオマー mixture of 2* benzyloxy cyclohexylamine reacting to an acylati...  
JP2010503634A
This invention relates to a process for the preparation of pyrido[2,1-a] isoquinoline derivatives of the formula wherein R1, R2, R3 and R4 are defined in the specification, comprising the optical resolution of an enamine of the formula w...  
JP2010503624A
the present invention -- especially -- the [blood coagulation] -- it is related with the methods for manufacturing the compound of formula (I) which has the anti-thrombus activity which checks an IXa factor, and them, and those use as a ...  
JP2010503625A
the present invention -- especially -- the [blood coagulation] -- it is related with the methods for manufacturing the compound of formula (I) which has the anti-thrombus activity which checks an IXa factor, and them, and those use as a ...  
JP4405675B2  
JP4406483B2  
JP4406482B2  
JP2010013370A
To provide a new zerumbone derivative usable as a chiral source for many uses, and to provide a method for producing the same.It has been found that zerumbone is epoxidized with m-chloroperbenzoic acid in the presence of ethyl acetate to...  
JP2010501487A
The present invention provides the method of dividing 2* piperidine *2* ethanol for piperidine *2* イル * Al Killen * alcohol, for example, in quantity 収率 and high エナンチオマー purity. Chiral alcoholic reagent (S) 2* piper...  
JPWO2008026678A1
本発明は、ラニレスタット製造のための鍵中 間体である光学活性なコハク酸イミド誘導体 (3)の製造法を提供する。即ち、下式(2 )(式中、R1は加水素分解により脱離...  
JP4399769B2  
JP4397987B2  
JP2010500403A
The present invention relates to the new manufacturing method of the 3* amino *5* フルオロ *4* dialkoxy pentanoic acid ester of the general formula (1) used as a precursor of 3* amino *5* フルオロ *4* oxo pentanoic acid: [Formula...  
JP2010001235A
To provide a method for producing an optically active 4-amino-3-substituted phenylbutanoic acid, by which the optically active 4-amino-3-substituted phenylbutanoic acid having a sufficient purity can be produced in simpler operations tha...  
JP4392661B2  
JP4389683B2  
JP2009544656A
[Means for Solution] The present invention relates to a preparing method of レベチラセタム, and relates to an improvement preparing method of レベチラセタム characterized by dynamic division by crystallization guidance of a...  
JP2009543759A
the present invention -- クロピド -- grele -- it is related with the new process for preparing the polymorphic form of 3 and (+) * (S) *alpha* (o* chlorophenyl) *6 of hydrogensulfate, i. e., formula I, and 7* dihydro2*thieno [c] pyri...  
JP4380325B2  
JP4381137B2
The compound 3-{(3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4- yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile or a pharmaceutically acceptable salt thereof; compositions containing the compound; and uses of the compound in the...  
JP2009542615A
The present invention relates to the acidification which generates the process of (R) - (*) -3- (カルバモ ylmethyl) -5-methylhexane acid, racemic division of acid racemate according to chlorination with active amine especially optica...  
JP2009542603A
The invention relates to a method for producing optically active 3-aminocarboxylic acid ester compounds. According to said method, an enantiomer mixture of a mono-N-acylated 3-aminocarboxylic acid ester, which mixture was previously enri...  
JP2009542590A
The present invention is a new substitution benzoキセピノ * isoxazole derivative of formula (I), Those use for disposal of those manufacturing methods and a disease, and/or prevention, It is related with a thing for those use for man...  
JP2009542728A
The present invention provides the compound denoted by general formula (I) which has solid arrangement of (-) or (+), or the salt permitted on those medicines. [Formula 1](Inside of a formula, R)1It is はH or a halogen atom, and is R.2...  
JP4377219B2  
JP2009541231A
The invention relates to a process for the manufacture of enantiomerically enriched or pure compounds of formula I wherein R1, R2, R3, R6, R7 and Q are defined as in claim 1 as well as their crystalline forms for the treatment of prolife...  

Matches 1,151 - 1,200 out of 4,296