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Matches 1 - 50 out of 5,337

Document Document Title
WO/2020/095322A1
Disclosed herein is an efficacious process for preparation of highly purified Glycopyrrolate tosylate in high yield. The process is being cost effective, environment friendly and easily scalable to high volume industrial production.  
WO/2020/082194A1
A process for producing an alkyl nitrite is provided, comprising: mixing oxygen and a circulating gas in a pre-reactor, mixing the oxidized circulating gas and an alkyl alcohol liquid in a first esterification tower to generate alkyl nit...  
WO/2020/084094A1
The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromati...  
WO/2020/079144A1
In a process for workup of mixed acid and wastewater from the nitration of aromatics in which the nitric acid present is converted by reaction with an aromatic under adiabatic conditions, a. at least one waste stream component selected f...  
WO/2020/053193A1
The invention relates to a safe and efficient process for the manufacture ω-nitrooxy-C3-10alkane-1-ols.  
WO/2020/053194A1
The invention relates to a process for the preparation of ω-nitroxyC3-1 0 alkane-1-ols comprising the nitration of an α,ω-C 3-10 alkanediol with a nitration agent, optionally in the presence of a nitrite trapping agent, characterized ...  
WO/2020/021323A1
A nitration reactor (10) incorporating sections of downward flow for use in preparing nitrated organic compounds. It comprises a first vertically-oriented reactor section (12), a second vertically-oriented reactor section (14), a connect...  
WO/2020/011626A1
The present invention refers to a crystalline 2-fluoro-3-nitrotoluene compound of formula (I), and a process for the preparation thereof. Furthermore, the present invention relates to a process for the synthesis of a compound of formula ...  
WO/2020/011817A1
The invention relates to a method for the continuous adiabatic nitration of benzene with nitric acid and sulfuric acid, the diluted sulfuric acid obtained during nitration being concentrated by flash evaporation in an evaporation device ...  
WO/2019/191363A3
Disclosed herein are improved methods for the preparation of oseltamivir, and intermediates useful thereto.  
WO/2019/216415A1
The present disclosure addresses the problem of providing a production method for a novel fluoromethyl derivative. The problem is solved by a production method that is for a fluorinated organic compound represented by formula (1) [in the...  
WO/2019/179110A1
Disclosed are a catalysis test paper prepared by compounding bacterial-cellulose-supported metal particles with plant fibers, and a preparation method therefor. Hydroxyl groups of bacterial cellulose are bonded with a nitrogen- or phosph...  
WO/2019/172184A1
Provided is a metal imide complex which has a stable structure and is able to be easily synthesized, while being capable of efficiently oxidizing various substrates. A metal imide complex which contains a metal and an imide that serves a...  
WO/2019/168269A1
The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using ...  
WO/2019/162149A1
The present invention relates to a process for preparing the hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hept en-1-yl]- 3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester of formula ...  
WO/2019/159596A1
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the pres...  
WO/2019/154728A1
The present invention relates to processes for preparation of 1 -nitrobenzene-2- alkyloxycarbonyl-5-carboxylic acid. In particular, the present invention relates to preparation of 1 -nitrobenzene-2-alkyloxycarbonyl-5-carboxylic acid by p...  
WO/2019/111280A1
The present invention discloses a process for nitration of benzene. More particularly, the present invention discloses an efficient, environmental friendly process for the nitration of benzene using a modified solid acid catalyst.  
WO/2019/102388A1
The present invention relates to a stable pharmaceutical composition of tetrofosmin or pharmaceutically acceptable salts thereof. It also relates to a lyophilized non-radioactive kit which upon reconstitution with 99mTc -pertechnetate so...  
WO/2019/099371A1
Provided herein are compounds that are prodrugs for mesalazine. Generally, the compounds described herein correspond to a mesalazine molecule wherein the amino group is replaced by a novel protecting group. For example, in the compounds ...  
WO/2019/031774A1
The present invention relates to a method for preparing latanoprostene bunod, and an intermediate therefor. According to the preparation method of the present invention, latanoprostene bunod can be efficiently and economically prepared w...  
WO/2019/016110A1
The invention discloses a method for preparation of 5-fluoro-2-methyl-3-nitrobenzoic acid and its methyl ester by conversion of 5-fluoro-2-methylbenzoic acid with fuming nitric acid and oleum and subsequent conversion with methanol.  
WO/2019/011709A1
The invention pertains to a process for manufacturing a mixture of straight-chain higher ethyleneamines and non-straight-chain higher ethyleneamines selected from branched higher ethyleneamines and cyclic higher ethyleneamines, or the ur...  
WO/2018/187542A1
Amine-catalyzed formation of cyclic allylic nitro compounds via nitro-aldol reaction is disclosed. A greener solvent and a cheaper, more robust catalyst than in previous reports are used in the nitro-aldol reaction. After screening a ran...  
WO/2018/179808A1
Provided is a method for producing alkyl nitrite by bringing an aqueous solution containing nitric acid and an alkanol into contact with a gas containing nitrogen monoxide to generate alkyl nitrite, wherein the reaction temperature is 60...  
WO/2018/162427A1
The invention relates to a method for continuous production of nitrobenzene by means of nitration of benzene with nitric acid and sulphuric acid, in which load change (i.e. a reduction or increase in the quantity of nitric acid supplied ...  
WO/2018/149813A1
The present invention relates to a process for preparing substituted 2-nitrobiphenyls via Suzuki coupling using a palladium catalyst with specific phosphorus ligands and a solvent mixture containing water and an organic solvent which is ...  
WO/2018/141642A1
The present invention relates to an improved process for the preparation of 2-chloro-4-fluoro-5-nitrobenzotrichloride. The present invention further relates to a process for the purification of 2-chloro-4-fluoro-5-nitrobenzotrichloride, ...  
WO/2018/144101A1
Described herein are labeling agents, specifically [11C]fluoroform, [11C]difluoromethane, [11C]fluoromethyl iodide, [11C]fluoromethyl bromide, [11C]fluoromethyl chloride, [11C]fluoromethyl trifluoromethansulfonate, [11C]difluoromethyl io...  
WO/2018/141451A1
The invention relates to a method for preferably adiabatic nitriding of nitrable aromatic organic compounds (aromates) and to a corresponding system, in particular a production plant (nitration plant) for carrying out said method.  
WO/2018/116107A1
Provided are IDO inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases ...  
WO/2018/107450A1
This invention provides an electrochemical process for producing a propiolactone compound comprising reacting a compound having at least one ethylenically unsaturated carbon-carbon double bond with carbon dioxide in the presence of an el...  
WO/2018/068733A1
The present invention provides a method for preparing nintedanib. The method of the present invention is carried out by using 4-halo-3-nitro-benzoic acid methyl ester (compound II) and 3-oxo-3-phenylpropionate (compound III) as raw mater...  
WO/2018/033866A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate comp...  
WO/2018/025295A1
The present invention relates to a process for preparing 3-pyrrolidine carboxylic acid derivatives, and particularly a simple process for preparing 5-substituted 3-pyrrolidine carboxylic acid derivatives. In addition, the present inventi...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/195619A1
The purpose of the present invention to provide a method for producing a nitrobenzene compound represented by general formula (1), which is economically preferable, and suitable for industrialization. The present invention pertains to a ...  
WO/2017/156688A1
Disclosed in the present invention is a preparation method for a nitroolefin derivative, the method comprising the following steps: adding an ethylene compound, sodium nitrite, manganese dioxide and 2,2,6,6-tetramethylpiperidinyloxy to a...  
WO/2017/142028A1
A metal-supported macromolecule and a use thereof as a catalyst, said metal-supported macromolecule being obtained by causing a ligand to react with a zinc compound or a cobalt compound, said ligand having an imidazole group that is bond...  
WO/2017/114058A1
The present invention discloses a method for preparing an optically active carbonyl compound, comprising the following steps: subjecting an α,β-unsaturated aldehyde or an α,β-unsaturated ketone to an asymmetric hydrogenation catalyze...  
WO/2017/100985A1
Disclosed is a method for preparing 2,2-dihalo-1,3-dicarbonyl derivatives. The method is applicable in a broad range of 1,3-dicarbonyl derivatives, which have various types of readily available raw materials. The method is utilized to pr...  
WO/2017/090569A1
This catalyst contains neodymium, sodium, and a ligand which is a compound represented by structural formula (1), wherein the neodymium and the ligand form a complex at a molar ratio of 1 : 2 (neodymium : ligand).  
WO/2017/089492A1
The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and...  
WO/2017/051856A1
A method for producing a specific enantiomer in a larger amount than the other enantiomer, said method comprising reacting a reaction substrate in the presence of cellulose nanofiber or a derivative thereof and a catalyst so as to improv...  
WO/2017/046118A1
The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNO2 in a continuous way, in which the n-butanol, an acid and NaNO2 are...  
WO/2017/008832A1
Polymer supported fluorinated compound of formula I, wherein the meaning for each R1 is as disclosed in the description. These compounds are useful as catalysts, particularly in Michael addition reactions under continuous flow.  
WO/2017/005606A1
The invention discloses a method for the preparation of carboxylic acid chlorides starting from methyl ketones with a sulfur chloride and a chlorinating reagent.  
WO/2017/005907A1
The invention relates to zeolitic adsorbents based on agglomerated crystals of zeolite X comprising barium, potassium and sodium. These adsorbents are applicable in the separation of fractions of aromatic C8 isomers, especially xylenes.  
WO/2017/005908A1
The invention relates to zeolitic adsorbents based on agglomerated crystals of zeolite X comprising barium, potassium and sodium. These adsorbents are applicable in the separation of fractions of aromatic C8 isomers, especially xylenes.  
WO/2016/198921A1
A process for removing impurities from crude nitrated aromatic products obtained during the nitration of aromatic compounds. The nitrated aromatic products (1) are purified by treatment with ammonia washing (102) followed by caustic wash...  

Matches 1 - 50 out of 5,337