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Matches 1 - 50 out of 5,249

Document Document Title
WO/2018/187542A1
Amine-catalyzed formation of cyclic allylic nitro compounds via nitro-aldol reaction is disclosed. A greener solvent and a cheaper, more robust catalyst than in previous reports are used in the nitro-aldol reaction. After screening a ran...  
WO/2018/179808A1
Provided is a method for producing alkyl nitrite by bringing an aqueous solution containing nitric acid and an alkanol into contact with a gas containing nitrogen monoxide to generate alkyl nitrite, wherein the reaction temperature is 60...  
WO/2018/162427A1
The invention relates to a method for continuous production of nitrobenzene by means of nitration of benzene with nitric acid and sulphuric acid, in which load change (i.e. a reduction or increase in the quantity of nitric acid supplied ...  
WO/2018/149813A1
The present invention relates to a process for preparing substituted 2-nitrobiphenyls via Suzuki coupling using a palladium catalyst with specific phosphorus ligands and a solvent mixture containing water and an organic solvent which is ...  
WO/2018/141642A1
The present invention relates to an improved process for the preparation of 2-chloro-4-fluoro-5-nitrobenzotrichloride. The present invention further relates to a process for the purification of 2-chloro-4-fluoro-5-nitrobenzotrichloride, ...  
WO/2018/144101A1
Described herein are labeling agents, specifically [11C]fluoroform, [11C]difluoromethane, [11C]fluoromethyl iodide, [11C]fluoromethyl bromide, [11C]fluoromethyl chloride, [11C]fluoromethyl trifluoromethansulfonate, [11C]difluoromethyl io...  
WO/2018/141451A1
The invention relates to a method for preferably adiabatic nitriding of nitrable aromatic organic compounds (aromates) and to a corresponding system, in particular a production plant (nitration plant) for carrying out said method.  
WO/2018/116107A1
Provided are IDO inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases ...  
WO/2018/107450A1
This invention provides an electrochemical process for producing a propiolactone compound comprising reacting a compound having at least one ethylenically unsaturated carbon-carbon double bond with carbon dioxide in the presence of an el...  
WO/2018/068733A1
The present invention provides a method for preparing nintedanib. The method of the present invention is carried out by using 4-halo-3-nitro-benzoic acid methyl ester (compound II) and 3-oxo-3-phenylpropionate (compound III) as raw mater...  
WO/2018/033866A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate comp...  
WO/2018/025295A1
The present invention relates to a process for preparing 3-pyrrolidine carboxylic acid derivatives, and particularly a simple process for preparing 5-substituted 3-pyrrolidine carboxylic acid derivatives. In addition, the present inventi...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/195619A1
The purpose of the present invention to provide a method for producing a nitrobenzene compound represented by general formula (1), which is economically preferable, and suitable for industrialization. The present invention pertains to a ...  
WO/2017/156688A1
Disclosed in the present invention is a preparation method for a nitroolefin derivative, the method comprising the following steps: adding an ethylene compound, sodium nitrite, manganese dioxide and 2,2,6,6-tetramethylpiperidinyloxy to a...  
WO/2017/142028A1
A metal-supported macromolecule and a use thereof as a catalyst, said metal-supported macromolecule being obtained by causing a ligand to react with a zinc compound or a cobalt compound, said ligand having an imidazole group that is bond...  
WO/2017/114058A1
The present invention discloses a method for preparing an optically active carbonyl compound, comprising the following steps: subjecting an α,β-unsaturated aldehyde or an α,β-unsaturated ketone to an asymmetric hydrogenation catalyze...  
WO/2017/100985A1
Disclosed is a method for preparing 2,2-dihalo-1,3-dicarbonyl derivatives. The method is applicable in a broad range of 1,3-dicarbonyl derivatives, which have various types of readily available raw materials. The method is utilized to pr...  
WO/2017/090569A1
This catalyst contains neodymium, sodium, and a ligand which is a compound represented by structural formula (1), wherein the neodymium and the ligand form a complex at a molar ratio of 1 : 2 (neodymium : ligand).  
WO/2017/089492A1
The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and...  
WO/2017/051856A1
A method for producing a specific enantiomer in a larger amount than the other enantiomer, said method comprising reacting a reaction substrate in the presence of cellulose nanofiber or a derivative thereof and a catalyst so as to improv...  
WO/2017/046118A1
The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNO2 in a continuous way, in which the n-butanol, an acid and NaNO2 are...  
WO/2017/008832A1
Polymer supported fluorinated compound of formula I, wherein the meaning for each R1 is as disclosed in the description. These compounds are useful as catalysts, particularly in Michael addition reactions under continuous flow.  
WO/2017/005606A1
The invention discloses a method for the preparation of carboxylic acid chlorides starting from methyl ketones with a sulfur chloride and a chlorinating reagent.  
WO/2017/005907A1
The invention relates to zeolitic adsorbents based on agglomerated crystals of zeolite X comprising barium, potassium and sodium. These adsorbents are applicable in the separation of fractions of aromatic C8 isomers, especially xylenes.  
WO/2017/005908A1
The invention relates to zeolitic adsorbents based on agglomerated crystals of zeolite X comprising barium, potassium and sodium. These adsorbents are applicable in the separation of fractions of aromatic C8 isomers, especially xylenes.  
WO/2016/198921A1
A process for removing impurities from crude nitrated aromatic products obtained during the nitration of aromatic compounds. The nitrated aromatic products (1) are purified by treatment with ammonia washing (102) followed by caustic wash...  
WO/2016/173960A1
The invention relates to an optimized synthesis of pregabalin and additional 4-aminobutane acids using an improved method for producing conjugated nitroalkenes. This is achieved by a nitro-aldol reaction of an aliphatic aldehyde with a n...  
WO/2016/140358A1
The purpose of the present invention is to provide a catalyst composite body which has an excellent reducing action. The above-described problem is able to be solved by a catalyst composite body according to the present invention, which ...  
WO/2016/127723A1
The present invention relates to the field of organic compound synthesis. Disclosed are salicylic acid trans-(β)-farnesene analogues, and a preparation method therefor and uses thereof. The compound is obtained by: mixing salicylic acid...  
WO/2016/128147A1
Disclosed is an apparatus for producing polyethylene glycol dinitrate. The apparatus includes providing continuously an acid composition and a glycol composition to a reaction apparatus; reacting the acid composition and the glycol compo...  
WO/2016/128924A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new c...  
WO/2016/127492A1
A tetra-phenolic compound/tetra-functionality epoxy resin, a preparation method and application thereof. The tetra-phenolic compound is obtained by reacting p-hydroxybenzaldehyde with an alkyl bromide, and then reacting the product there...  
WO/2016/125185A2
The present invention provides the process for the preparation of 4-substituted-1- (trifluoromethoxy) benzene compounds..  
WO/2016/125185A3
The present invention provides the process for the preparation of 4-substituted-1- (trifluoromethoxy) benzene compounds..  
WO/2016/118450A1
The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an...  
WO/2016/114310A1
The purpose of the present invention is to provide a novel method for producing a nitro compound that is a precursor compound of a diamine compound, which is a raw material for a polyimide and/or polyamic acid used in a liquid crystal al...  
WO/2016/095684A1
The present invention provides a himbacine analogue and a method for preparing an intermediate thereof, and particularly provides a new method for preparing a compound A, a compound 4, a compound D and a compound C. In the solution for p...  
WO/2016/086722A1
Disclosed is a preparation method for an isoxazole compound and an intermediate thereof, the method comprising: a compound (I), as the starting material, is subjected to a substitution reaction with a compound (II) in the presence of a b...  
WO/2016/086710A1
Disclosed is a carboxylic acid preparation method. The method is characterized in that: a compound (II) reacts in the presence of hydrogen peroxide and a base to produce a target product (I) represented by the following equation: R1 is a...  
WO/2016/082780A1
The present invention relates to α-asary-laldehyde ester, a preparation method therefor, and an application thereof. The chemical structure of the related α-asary-laldehyde ester is represented by formula I. A related application is an...  
WO/2016/079759A4
The present invention relates to a novel simple, efficient and single-step process for esterification of aldehydes using a heterogeneous catalyst with high yields. More particularly, the present invention relates to a novel simple, effic...  
WO/2016/079138A1
A method for continuously producing a product (A1) by way of at least two coupled-together chemical reactions (C1, C2), wherein at least two input substances (E1, E2) are fed to a first chemical reaction (C1), wherein a plurality of inte...  
WO/2016/079759A9
The present invention relates to a novel simple, efficient and single-step process for esterification of aldehydes using a heterogeneous catalyst with high yields. More particularly, the present invention relates to a novel simple, effic...  
WO/2016/079759A1
The present invention relates to a novel simple, efficient and single-step process for esterification of aldehydes using a heterogeneous catalyst with high yields. More particularly, the present invention relates to a novel simple, effic...  
WO/2016/058881A2
The present invention relates to a process for the preparation of a compound of formula (I), wherein R1 is hydrogen, fluoro or chloro; which process comprises a) reacting a compound of formula (II), wherein R1 is hydrogen, fluoro or chlo...  
WO/2016/058882A1
The invention relates to a process for the preparation of a compound of formula I (I), wherein R1 is hydrogen, fluoro or chloro; which process comprises a) reacting a compound of formula II (II), wherein R1 is hydrogen, fluoro or chloro;...  
WO/2016/058881A3
A process for the preparation of a compound of formula (I) wherein R1 is hydrogen, fluoro or chloro; which process comprises: a) reacting a compound of formula (II) wherein R1 is hydrogen, fluoro or chloro; with a nitration agent to the ...  
WO/2016/050759A1
The invention relates to a method for producing dinitrotoluene, comprising the following steps: a) nitrating toluene with a mixture of nitric acid and sulfuric acid and subsequently separating a sulfuric-acid-containing aqueous phase tha...  
WO/2016/045415A1
A method for asymmetrically catalyzed synthesis of a γ-nitropyrazole amide compound, where a nitroalkene and an α,β-unsaturated pyrazole amide are employed as raw materials, a complex formed by a chiral amine oxide and a rare earth me...  

Matches 1 - 50 out of 5,249