| Document |
Document Title |
|
WO/2003/086078A1 |
A method for reducing calcified arterial plaque buildup and cellular malfunction with the administration of therapeutically effective dosages of a compounded coordination complex of magnesium. The method includes steps for making and adm...
|
|
WO/2003/087032A1 |
Compounds are described, having general formula (I) and their use as acaricides, insecticides and/or fungicides.
|
|
WO/2003/084912A1 |
Benzoylcyclohexanedione derivatives of formula (I) and use thereof as herbicides are disclosed. In said general formula (I) R1a, R1b, R1c, R2, R3, R4 and R5 = various groups, X1 = a bridging atom, X2 = a hydrocarbon chain and X3 = a chal...
|
|
WO/2003/083063A2 |
The present invention provides common ligand mimics that act as common ligands for a receptor family. The present invention also provides bi-ligands containing these common ligand mimics. Bi-ligands of the invention provide enhanced affi...
|
|
WO/2003/082860A1 |
A process for producing an indole compound represented by the formula (2) which comprises reducing a 2-nitrobenzylcarbonyl compound represented by the formula (1) (wherein R1 and R2 each independently represents hydrogen or optionally su...
|
|
WO/2003/080553A1 |
The invention relates to substituted cyclopentene derivatives, to a method for the production thereof and to the use of the same for producing pharmaceuticals which are especially used to treat and/or prevent thromboembolic diseases.
|
|
WO/2003/080552A2 |
A method of preparing prostanoid cross-conjugated dienones, via a tandem conjugate addition-Peterson olefination reaction route is described. Such compounds may be useful in medicine and other fields.
|
|
WO/2003/080555A1 |
A process for producing a dicarboxylic acid compound represented by the formula (4): (4) (wherein R1 and R2 are the same or different and each represents lower alkyl; and the wavy line indicates that this compound is the (E) or (Z) isome...
|
|
WO/2003/066546A1 |
A process for producing a biaryl compound, characterized by reacting an arylhydrazine compound, hydrogen peroxide, and an aryl compound. When the reaction is conducted in the presence of a given metal or a compound of the metal or in the...
|
|
WO/2003/066035A2 |
Compounds, compositions and methods for altering insulin secretion, particularly in the context of treatment of subjects having, or suspected of being at risk for having, diabetes mellitus. The compounds have the following struture (I): ...
|
|
WO/2003/064399A1 |
A process for producing a quinazolin−4−one derivative represented by the following formula (2): (2) (wherein R1, R2, R3, and R4 each represents a group not participating in the reaction and R1, R2, R3, and R4 may be bonded to each ot...
|
|
WO/2003/062187A1 |
A process by which 2,5-bis(trifluoromethyl)nitrobenzene can be produced from an industrially easily available material in high yield through a small number of steps under mild reaction conditions using an easily handleable substance with...
|
|
WO/2003/060852A2 |
An osmium−assisted process for the oxidative cleavage of oxidizable organic compounds such as unsaturated organic coumpounds, including alkenes and olefins into aldehydes, carboxylic acids, esters, or ketones. The process uses a metal ...
|
|
WO/2003/055600A1 |
A catalyst comprising a cyclic acylurea compound having a cyclic acylurea skeleton represented by the general formula (I): (I) [wherein R is hydrogen or a hydroxyl−protecting group&semi G is carbon or nitrogen&semi and n is 1 or 2, wit...
|
|
WO/2003/055849A1 |
The invention relates to a method for the production of solutions a quaternary cation and an anion from a deprotonated hydroxy aromatic in an organic solvent by a reactive extraction of a quaternary salt in the presence of an aqueous hyd...
|
|
WO/2003/051801A2 |
a,ß,ß-Trifluorostyrene and derivatives thereof synthesized in two steps from 1,1,1,2-tetrafluoroethylene. In the first step, 1,1,1,2-tetrafluoroethylene is reacted with a base, a metal salt such as zinc chloride and an optionally amine...
|
|
WO/2003/051805A2 |
This invention provides estrogen receptor modulators of formula (I), having the structure (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10, are as defined in the specification, or a pharmaceutically acceptable salt thereof.
|
|
WO/2003/049690A2 |
The present invention relates to the inhibition of HIV integrase, and to the treatment of AIDS or ARC by administering compounds of the following formula, or a tautomer of said compound, or a pharmaceutically acceptable salt, solvate or ...
|
|
WO/2003/050066A1 |
This invention is directed to functionalized higher diamondoids having at least one functional group. These derivatives have a higher diamondoid nucleus and up to six independently selected functional groups. The functionalized higher di...
|
|
WO/2003/048090A1 |
There is provided processes for metal mediated reactions, particularly cross coupling and carbometallation reactions, wherein the metal is present as a catalyst system comprising a catalyst microencapsulated within a permeable polymer mi...
|
|
WO/2003/043624A1 |
Compounds that are dual aP2/k-FABP inhibitors are provided having the formula (I), wherein A, B, X, Y, R?1¿, R?2¿ and R?3¿ are as described herein. A method is also provided for treating diabetes and related diseases, especially Type ...
|
|
WO/2003/042150A1 |
Because of having an anti−arthritic effect, inhibiting bone fracture induced by arthritis and having a high safety, benzophenone derivatives represented by the following general formula or salts thereof are useful as remedies for arthr...
|
|
WO/2003/042153A1 |
A pest control agent which is highly effective in pest control and is highly safe for crops, natural enemies to pests, and mammals. It is a difluoroalkene derivative represented by the following general formula [1] or a pharmacologically...
|
|
WO/2003/039456A2 |
Provided are processes for the synthesis of aniline derivatives, specifically certain aniline derivatives which have activity as thyroid receptor ligands.
|
|
WO/2003/035008A2 |
Novel stilbenoid compounds and their prodrug forms are disclosed, which serve as potent vascular targeting agents useful for the treatment of solid tumor cancers and other diseases associated with unwanted neovascularization. The novel s...
|
|
WO/2003/029189A1 |
A process for producing a compound represented by the formula [IV] which comprises the steps (1) to (3): a step in which a compound represented by the formula [I] is reacted with either a compound represented by the formula [VI] or a mix...
|
|
WO/2003/022853A1 |
The present invention relates to a method for the preparation of hexahydro-furo[2,3-b]furan-3-ol as well as novel intermediates for use in said method. More in particular the invention relates to a stereoselective method for the preparat...
|
|
WO/2003/020684A1 |
The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.
|
|
WO/2003/020683A1 |
Aromatic compounds are mononitrated by reaction with a nitrating agent, preferably nitric acid, in a phosphonium salt ionic liquid.
|
|
WO/2003/018552A2 |
The present invention is directed to protected amino acid halide monomers and oligomers, and to their use in the efficient sythesis of polyamides. The present invention is further directed to the use of -haloenamine reagents, which may o...
|
|
WO/2003/018070A1 |
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compound...
|
|
WO/2003/018551A1 |
There is provided a compound of formula (I) and pharmaceutically-acceptable derivatives (including prodrugs) thereof, which compound and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like prot...
|
|
WO/2003/014104A1 |
The invention concerns novel 1-benzoxepin derivatives, methods for preparing them, their use as fungicides, in particular in the form of fungicidal compositions, as well as methods for controlling phytopathogenic fungi of crops using sai...
|
|
WO/2003/011818A1 |
A process for producing an acid anhydride which comprises reacting a carboxylic acid, preferably one having a polymerizable group, with a sulfonyl halide compound in the presence of a tertiary amine or of a tertiary amine and an inorgani...
|
|
WO/2003/011811A1 |
The invention relates to a method for the continuous production of 2-bromo-2-nitro-1, 3-propanediol, according to which: I) nitromethane and one or two aqueous solutions containing formaldehyde and alkali hydroxide are intermixed, with m...
|
|
WO/2003/011810A1 |
A method for the regioselective ortho-directed nitration of phenolic compounds useful for the preparation of ortho-nitro-phenols according to formula (I) is described.
|
|
WO/2003/009936A2 |
A palladium-catalysed carbon-carbon bond forming reaction in compressed carbon dioxide is provided wherein at least one of the reagents used in said reaction is bounded to a solid polymer support. In a second aspect, a palladium-catalyse...
|
|
WO/2003/009807A2 |
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituded phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited...
|
|
WO/2003/006435A1 |
The use of iodine as a primary oxidant for TEMPO provides a novel and selective method for oxidizing alcohols to their corresponding carbonyl compounds.
|
|
WO/2003/006151A1 |
A microencapsulated catalyst is prepared by dissolving or dispersing a catalyst in a first phase (for example an organic phase), dispersing the first phase in a second, continuous phase (for example an aqueous phase) to form an emulsion,...
|
|
WO/2003/006670A2 |
The present invention relates to novel inhibitors of formula (I) of Factors VIIa, IXa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preven...
|
|
WO/2003/006011A1 |
The present invention relates to novel inhibitors of formula (I) of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or pr...
|
|
WO/2003/004446A1 |
A process for producing a fluorinated alcohol from a fluoroalkyl halide through a one−stage reaction in high yield with high selectivity without using a highly toxic compound such as a heavy metal compound, which is difficult to handle...
|
|
WO/2003/002526A1 |
A method of oxidizing primary and secondary alcohols to an aldehyde or ketone using a fluorous sulfoxide or a fluorous sulfide is disclosed. The method includes regenerating and recycling the fluorous sulfoxide which has the structure, w...
|
|
WO/2003/002495A1 |
The present invention relates to novel treatment of adrenocortical hypersecretion. More specifically, the present invention relates to chemical substances having selective adrenal toxicity for use in medicine, especially for treatment of...
|
|
WO2002008187A9 |
The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising su...
|
|
WO/2003/000644A1 |
Compounds which are capable of generating acid on photolysis are disclosed, and the uses of these compounds, especially for deprotecting the termini of nucleic acid molecules or peptides during synthesis of arrays. The compounds describe...
|
|
WO/2002/100392A1 |
The present invention provides an extended release oral dosage form of prodrugs of gabapentin and other GABA analogs, which dosage forms exhibit reduced toxicity. The dosage forms are particularly useful in administering those prodrugs o...
|
|
WO/2002/100347A2 |
The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA anal...
|
|
WO/2002/096804A2 |
Disclosed are processes for the recovery and purification of higher diamondoids from a hydrocarbonaceous feedstock. Specifically disclosed is a multi-step recovery process for obtaining diamondoid compositions enhanced in tetramantane co...
|
