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WO/2012/059585 |
The present invention relates to a process for the preparation of substituted N-(benzyl)cyclopropanamines of the general formula (II) starting from N-[(aryl)methylene]cyclopropanamine derivatives. The present invention further provides t...
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WO/2012/057226 |
Provided is a reduction catalyst, which comprises a conductive carbon and a palladium-gold ally that is supported by the carbon, and wherein the alloying degree of the alloy is 50-100%. This palladium-supporting catalyst has excellent re...
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WO/2012/056458 |
The present invention relates to processes for the preparation of (2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride (Fingolimod) and pharmaceutically acceptable salts thereof, and intermediates formed in such processes.
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WO/2012/052407 |
The invention relates to a process for purifying aniline prepared by gas phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so as to obtain at least two liquid process p...
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WO/2012/052829 |
The present invention provides novel process for the preparation of renin inhibitor Aliskiren or its derivatives, and its pharmaceutically acceptable salts. The present invention also provides novel intermediates used in the preparation ...
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WO/2012/051737 |
Provided is a preparation method of cinacalcet I and pharmaceutical salts thereof, which comprises the following steps: a) reacting compound II with compound III in the presence of an alkali via SN2 reaction to obtain compound IV; b) pro...
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WO/2012/052409 |
This invention relates to novel compounds suitable as precursors for the preparation of certain 18F labelled positron emission tomography (PET) tracers. Furthermore, the invention relates to the preparation of such precursor molecules an...
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WO/2012/048845 |
Disclosed are halogenated diethyltoluenediamines of formula I, wherein either R1 is an amino group and R2 is chlorine or bromine, or R2 is an amino group and R1 is chlorine or bromine, and isomeric mixtures thereof. The halogenated dieth...
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WO/2012/046782 |
A method for producing trans-1,4-bis(aminomethyl)cyclohexane involves: a nuclear hydrogenation step of subjecting at least one type of terephthalic acid or a derivative thereof selected from a group consisting of terephthalic acid, terep...
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WO/2012/046781 |
A method for producing a bis(aminomethyl)cyclohexane involves: a nuclear hydrogenation step of subjecting at least one type of a phthalic acid or a derivative thereof selected from a group consisting of phthalic acids, phthalate esters, ...
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WO/2012/044456 |
The present invention provides methods that are used to decolorize compositions containing one or more amines in the presence of one or more weak acids. Significantly, the weak acids, particularly organic acids such as glacial acetic aci...
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WO/2012/041405 |
The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a ...
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WO/2012/041707 |
The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a ...
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WO/2012/041359 |
The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a ...
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WO/2012/039098 |
Disclosed herein is a method for producing an alcohol and an amine from an amide under an atmosphere of hydrogen with the use of, as a catalyst, a ruthenium complex that is easily prepared, easy to handle, and relatively cheaply obtained...
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WO/2012/034627 |
The invention relates to compounds according to formula (1), which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices that contain said compounds.
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WO/2012/035507 |
The present invention relates to a production method of hydrogel-metal composite which is prepared in order to be used in hydrogen production and various environmental practices, and prepared in the form of hydrogels comprising synthesiz...
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WO/2012/035061 |
A new process for the diamination of alkenes is provided, as well as the new compounds prepared thereof. A process for the preparation of the primary amines obtained from the diaminated alkenes of the provided preparation process is also...
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WO/2012/035507 |
The present invention relates to a production method of hydrogel-metal composite which is prepared in order to be used in hydrogen production and various environmental practices, and prepared in the form of hydrogels comprising synthesiz...
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WO/2012/034933 |
The invention relates to a method for producing an aromatic amine by reacting a corresponding aromatic alcohol with an amination agent selected from the group consisting of ammonia, primary amines and secondary amines, in the presence of...
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WO/2012/031672 |
The invention relates to a continuous method for producing primary aliphatic amines having 9 to 18 carbon atoms in the molecule by the reductive amination of the corresponding aliphatic aldehydes. The reaction occurs without solvent in t...
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WO/2012/029963 |
A process for producing an aromatic amine compound, which comprises reacting an aromatic halide, an amine compound and an alkali metal alkoxide with one another in the presence of a compound having a trivalent phosphorous atom and a nick...
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WO/2012/028323 |
Described is a process for the preparation of halogenated 4,4'-methylene-bis- anilines by a direct halogenation of 4,4'-methylene-bis-anilines. High yields and a flexible control of the grade of halogenation at the aromatic rings can be ...
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WO/2012/029962 |
This method for producing an aromatic amine compound reacts an aromatic iodide, an amine compound, and an alkali metal alkoxide under the presence of a copper compound and a compound having a trivalent phosphorus atom.
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WO/2012/022460 |
A process for the chlorination of alkylanilines is provided allowing a highly selective chlorination in the meta-position of the aromatic ring. This is achieved by reacting a mixture comprising the alkylaniline and sulfuric acid with chl...
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WO/2012/023546 |
The purpose of the present invention is to provide a process by which hydrogen or heavy hydrogens can be easily produced without using large-scale equipment and a process by which hydrogenation (protiation, deuteration or tritiation) can...
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WO/2012/018310 |
Title: Process for the production of highly pure dicyclohexylamine from by- products resulting from the production of cyclohexylamine Process for the production of highly pure dicyclohexylamine during the production of cyclohexylaminefro...
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WO/2012/017114 |
The present invention relates to a method for synthesizing azetidine, which is based on radical scission reactions, which is more simple and direct than the methods customarily used. In the said method, a compound containing a substitute...
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WO/2012/013563 |
The invention relates to a method for producing 3-dimethlaminopropylamine (DMAPA) by reacting 3- demethylaminopropionitrile (DMAPN) with hydrogen in the presence of a catalyst, characterized in that the DMAPN used has a 2-(dimethylaminom...
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WO/2012/015052 |
Disclosed are: a layered structure that has a substrate and a hole-injection and/or hole-transport layer that contains an aromatic compound that has, in a side chain, at least one species of group that has a cationic center; an electroni...
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WO/2012/013677 |
The present invention relates to a process for restoring the activity of spent catalysts for the hydrogenation of aromatic nitro compounds, in which a regeneration comprising at least one first burnoff stage, a first wash stage, a second...
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WO/2012/010608 |
The invention relates to a method for producing 2,5-diaminotoluene by catalytic hydrogenation in an aprotic-nonpolar solvent or in a mixture made of two or more aprotic-nonpolar solvents with hydrogen in the presence of a catalyst or a m...
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WO/2012/010651 |
The present invention relates to method for the preparation of an ω-amino-alkane(thio)amide having the formula (3). Furthermore, novel intermediates and partial reaction steps of the claimed method are disclosed.
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WO/2012/010651 |
The present invention relates to method for the preparation of an ω-amino-alkane(thio)amide having the formula (3). Furthermore, novel intermediates and partial reaction steps of the claimed method are disclosed.
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WO/2012/005693 |
The present invention relates to a method for the synthesis of an α amino acetal, comprising (i) oxidizing a tertiary amine in the presence of a copper catalyst, at least one oxidant and a solvent, or (ii) reacting a secondary amine and...
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WO/2012/005692 |
The present invention relates to a three component coupling reaction. In this reaction a terminal alkyne or a salt thereof, a geminal dihalide and a primary or secondary amine are reacted in the presence of a copper (I) catalyst to produ...
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WO/2012/001531 |
Provided herein are novel processes for the preparation of phenylcyclopropylamine derivatives, which are useful intermediates in the preparation of triazolo[4,5-d]pyrimidine compounds. Provided particularly herein are novel, commercially...
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WO/2012/000952 |
The invention relates to a method for producing tri-n-propyl amine (TPA), wherein di-n-propyl amine is reacted in the presence of hydrogen and a copper-containing heterogeneous catalyst. The integrated method for producing TPA comprises ...
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WO/2011/162350 |
Provided are: a process for producing a high-quality aqueous solution of a diamine dicarboxylic acid salt by simple and easy steps; and a process for producing a polyamide. The process for producing a high-quality aqueous solution of a d...
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WO/2011/159564 |
Processes include producing hexamethylenediamine (HMD), adiponitrile (ADN), adipamide (ADM) and derivatives thereof from fermentation broths containing diammonium adipate (DAA) monoammonium adipate (MAA) and/or adipic acid (AA).
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WO/2011/159557 |
Processes for producing nitrogen containing compounds include producing hexamethylenediamine (HMD), adiponitrile (ADN), adipamide (ADM) and derivatives thereof from adipic acid (AA) obtained from fermentation broths containing diammonium...
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WO/2011/158258 |
The invention discloses an improved process for the conversion of isobutylene to tertiary butylamine with conversion up to 50 % at pressure lower than 40 bar.
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WO/2011/158176 |
The invention provides compounds of the Formula (I), in which W is independently selected from W1, W2, W3, W4, W5, or W represents a pair of substituents independently selected from H, alkyl, aryl or amide in which the amide is optionall...
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WO/2011/147308 |
Provided is a solid base catalyst containing porous carrier, and organic base and inorganic base loaded on the carrier. The solid catalyst is particularly suitable for the catalytic synthesis of 4-amino-diphenylamine (4-ADPA).
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WO/2011/148976 |
Disclosed is a method for producing 4-nitrodiphenylamine, which enables the post-treatment of a reaction mixture to be simply performed. More specifically disclosed are a method for producing 4-nitrodiphenylamine comprising reacting anil...
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WO/2011/146556 |
Processes that make nitrogen-containing compounds include converting succinic acid (SA) or monoammonium succinate (MAS) derived from a diammonium succinate (DAS)- or MAS-containing fermentation broth to produce such compounds including d...
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WO/2011/145019 |
The present invention relates to an improved process for the preparation of biologically active diphenylpropylamine derivatives. The present invention specifically relates to an improved fesoterodine of formula (I) and its pharmaceutical...
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WO/2011/144481 |
The invention relates to a process for continuous preparation of tolylenediamine by liquid phase hydrogenation of dinitrotoluene with hydrogen in the presence of a suspended nickel-containing catalyst in a reactor with a product removal ...
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WO/2011/146440 |
Processes include providing a clarified diammonium succinate (DAS)- or monoammonium succinate (MAS)- containing fermentation broth; distilling the broth of an overhead that includes water and ammonia, and a liquid bottoms that includes S...
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WO/2011/141642 |
The degradation of an absorbing solution comprising organic compounds having an amine function in an aqueous solution is substantially reduced in the presence of a small quantity of degradation inhibitor additives belonging to the family...
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