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WO/2021/204712A1 |
The invention relates to a process for the preparation of a compound of formula [Chem I], formula (I), said method being characterized in that it comprises at least one step of oxidizing sulfonated triphenyl methane of formula [Chem V] w...
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WO/2021/204711A1 |
Disclosed is a process for synthesizing a compound of formula [Chem I], comprising at least the following steps: a) condensing a benzaldehyde compound of formula [Chem II] with dialkyl aniline of formula [Chem III] to obtain triphenyl me...
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WO/2021/071033A9 |
The present invention relates to a method for preparing diethylamino hydroxybenzoyl hexyl benzoate and, specifically, to: a method for preparing diethylamino hydroxybenzoyl hexyl benzoate, which has a simple preparation process and can b...
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WO/2021/203255A1 |
A method for purification of organic amines, comprising introducing a resin polymer matrix to a liquid containing at least an organic amine bonded to at least one metallic element, wherein the resin polymer matrix is embedded with an ami...
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WO/2021/196777A1 |
The present invention belongs to the technical field of fine chemical engineering, and specifically relates to a polymerizable surfactant with reducibility and a preparation method therefor. The polymerizable surfactant with reducibility...
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WO/2021/196775A1 |
The present invention belongs to the field of polymer synthesis, and specifically discloses a reducing agent monomer for preparing a styrene-acrylic emulsion by means of oxidation-reduction at a normal temperature, and a synthesis method...
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WO/2021/185154A1 |
A pharmaceutical composition comprising tizoxanide and choline hydroxide, a choline salt of tizoxanide and crystal form thereof, and a pharmaceutical use thereof. A mixture of tizoxanide and choline hydroxide, or a salt thereof and cryst...
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WO/2021/177219A1 |
Provided is a catalyst which can be used for enabling a reductive amination reaction under a low-temperature low-hydrogen-pressure condition, comprises cobalt supported on an oxide, and is characterized by being produced by a method incl...
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WO/2021/168988A1 |
The present invention provides a synthesis method for a fluorine-containing chiral amine compound. The synthesis method comprises: reacting an amino donor with a fluorine-containing dihydroxy ketal compound under the catalysis of transam...
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WO/2021/156578A1 |
The invention relates to anti-UV molecules of natural origin, and to the process for the synthesis thereof and also the process for the synthesis of analogues thereof. More particularly, it relates to a two-step process for the synthesis...
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WO/2021/154636A1 |
A method of applying fragrance to a fabric substrate includes bleaching a cotton fabric substrate, mercerizing the cotton fabric substrate, and preparing the cotton fabric substrate for dyeing. The method includes making a foam containin...
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WO/2021/148043A1 |
The present invention relates to the field of drugs, and particularly relates to a nitrophenyl ether compound having structural characteristics of a general formula (I), a stereoisomer, a metabolite, a metabolic precursor, a prodrug, a s...
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WO/2021/138443A1 |
Methods and compositions for modifying the course and severity of neuropsychiatric disorders. The method includes administering a composition to a subject suffering from a neuropsychiatric disorder, wherein the composition includes a sub...
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WO/2021/119899A1 |
A process for producing a supported catalyst comprising metal nanoparticles, said process comprises the following steps: (a) preparing a supported catalyst comprising metal nanoparticles; (b) peducing the catalyst of step (a); (c) treati...
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WO/2021/114166A1 |
A process for preparing a N-substituted alkanolamine of formula (I) and/or a N-substituted diamine of formula (II) from glycolaldehyde is provided, which comprises reacting glycolaldehyde with an aminating agent of formula (III) in a sol...
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WO/2021/116419A1 |
The present invention relates to a catalytic material for the preparation of one or more of 4,4'- methylenedianiline, 2,2'-methylenedianiline, 2,4'-methylenedianiline, and oligomers of two or more thereof, the catalytic material comprisi...
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WO/2021/116608A1 |
The present invention relates to a process for the continuous synthesis of heavy alkyl acrylates by a transesterification reaction using hydrozincite as a heterogeneous catalyst.
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WO/2021/110472A1 |
A process for preparing an amine by reacting an aldehyde and/or ketone with a nitrogen compound selected from the group consisting of ammonia and primary and secondary amines, followed by hydrogenation of the resulting reaction product i...
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WO/2021/103327A1 |
The present invention relates to a preparation method for an aprepitant intermediate impurity. The preparation method comprises the following reaction steps: (A) carrying out a Grignard reaction on a raw material 1 and a Grignard reagent...
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WO/2021/105337A1 |
The present invention relates to a process for synthesizing large scale a compound of formula (I), or pharmaceutically acceptable salt thereof, which is useful as the key intermediate for the synthesis of compounds for prophylaxis and tr...
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WO/2021/099456A1 |
The present invention relates to a process for the conversion of propylene oxide to 1-amino-2- propanol and/or di(2-hydroxypropyl)amine comprising (i) providing a catalyst comprising a zeolitic material comprising YO2 and optionally comp...
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WO/2021/099225A1 |
The present invention relates to an improved chromium-free Cu-Al catalyst for the hydrogenation of carbonyl groups in organic compounds, characterized in that the catalyst contains zirconium in a proportion of 0.5 to 30.0 wt.%. The inven...
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WO/2021/093426A1 |
A method for synthesizing hydroxybenzylamine, relating to the technical field of organic synthesis. The principle of the method comprises: a demethylation reaction of methoxybenzylamine under the effect of hydrobromic acid. The present i...
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WO/2021/095091A1 |
The present invention relates to provision of: an intermediate which enables, for example, the achievement of an aminoaryl derivative by being reacted, as a nucleophilic reaction reagent, with an electrophilic reagent or the like, withou...
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WO/2021/093292A1 |
Disclosed is a co-production method for 2-(2-amino-propoxy)ethanol and polyether polyol. The method comprises the steps of: (1) performing a chain-linking reaction on ethylene glycol and propylene oxide to obtain a mixed product A; (2) a...
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WO/2021/092320A1 |
An alkanolamine composition having a recycle content value is obtained by reacting a recycle content feedstock to make a recycle content alkanolamine or by deducting from a recycle inventory a recycle content value applied to an alkanola...
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WO/2021/088456A1 |
The invention uses a production method of first generating a monoquaternary ammonium salt intermediate, and then generating a target biquaternary ammonium salt product. The whole production process achieves continuous production of conti...
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WO/2021/068449A1 |
The present invention relates to the technical field of cellulose nanofiber membrane catalysts, and relates in particular to a modified CNF membrane capable of catalytically degrading 4-nitrophenol, a preparation method therefor and an a...
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WO/2021/052271A1 |
A magnolol derivative and a preparation method therefor and an application thereof. The magnolol derivative has a structure represented by formula (1). The magnolol derivative has good water solubility, is colorless and transparent after...
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WO/2021/052270A1 |
The present invention relates to the field of honokiol derivatives. Disclosed are a honokiol derivative, a preparation method therefor and the use thereof, wherein the derivative has a structure as shown in formula (I). The honokiol deri...
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WO/2021/047603A1 |
The present application provides a compound of formula II and a method for preparing a compound of formula I, i.e., 2-isopropyl-4-methylpyridin-3-amine by using same. The compound of formula I can be applied to synthesis of KRAS inhibito...
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WO/2021/047490A1 |
Disclosed in the present invention is a method for preparing dexibuprofen, comprising: (1) after adding toluene into a reaction kettle, adding ibuprofen and n-octyl-d-glucamine, heating to 76 to 80°C, keeping the temperature and reactin...
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WO/2021/036158A1 |
The present invention relates to the technical field of organic small molecule hole injection/transport materials. Disclosed are an organic small molecule hole injection/transport material and a preparation method therefor and an applica...
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WO/2021/028506A1 |
The invention relates to processes for preparing 2 -methoxymethyl-p-phenylenediamine (I), cosmetically acceptable salts thereof, or mixtures thereof.
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WO/2021/024271A1 |
A continuous process(200) for manufacture of dl-2-nitro-1-butanol from 1-nitropropane is disclosed. The process mixes aqueous solution of sodium hydroxide (A) and a solution of 1-nitropropane (B) dissolved in alcohol(203) at a first mola...
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WO/2021/003462A1 |
The present invention relates to novel cationic lipids of formula I, and more specifically formula IV. These are used, for example, in liposomes for the delivery of nucleic acids to cells.
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WO/2020/257930A1 |
Stable formulations of alkyl benzidine compounds and methods of making and using same. A short chain diol and an alkyl benzidine compound are combined together in solution at low pH and the solution is heated with moderate heat. The stab...
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WO/2020/249427A1 |
A process for the conversion of glycolaldehyde with an aminating agent in the presence of hy-5 drogen and of a catalyst, wherein the conversion is carried out in the gas phase.
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WO/2020/248127A1 |
A borohydride reduction stabilizing system and a method for reducing an ester to an alcohol. The borohydride reduction stabilizing system comprises: a borohydride reducing agent and a stabilizing agent for stabilizing the borohydride red...
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WO/2020/249428A1 |
A process for the manufacture of ethyleneamines and ethanolamines, comprising the steps of (i) converting a glycolaldehyde derivative of formula (II), in which R2, R3 are - the same or different -hydrogen, alkyl, such as C1-6-alkyl, or c...
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WO/2020/249426A1 |
A process for the conversion of glycolaldehyde with an aminating agent in the presence of hy- drogen and of a catalyst in a glycolaldehyde conversion reactor, wherein one or more organic carboxylic acids are fed into the glycolaldehyde c...
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WO/2020/237806A1 |
The present invention relates to the field of organic synthesis. Provided is a preparation method for 4-fluorine-3-methoxyl-5-methylaniline hydrochloride. A synthetic route of the preparation method for 4-fluorine-3-methoxyl-5-methylanil...
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WO/2020/238753A1 |
A preparation method for salicylamine acetate, comprising preparing an amino-protected intermediate from salicylaldehyde, and reacting the intermediate with acetic acid to prepare an acetate.
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WO/2020/221685A1 |
The invention relates to a method for manufacturing a concentrate enriched in iron mineral content from an ore, which contains an iron mineral and silicate, by reverse flotation, which method comprises the step of (c) adding a compound o...
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WO/2020/215895A1 |
The present invention relates to the technical field of medicine, and relates to derivatives represented by formula 1 and formula 2 in which a carboxylic acid group is introduced into the structure of ginkgolide B by means of a hydroxyl ...
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WO/2020/212510A1 |
The present invention is directed to methods for the asymmetric synthesis of esketamine. The present invention is further directed to key intermediates in the asymmetric esketamine synthesis. In one embodiment, the invention is an asymme...
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WO/2020/212157A1 |
The invention concerns a new, efficient process for the preparation of enantiomerically pure norepinephrine (also known as noradrenaline), or an addition salt thereof, using a catalytic hydrogenation system under hydrogen donor transfer....
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WO/2020/212227A1 |
The present invention relates to a new process for the production of substituted 2-[2-(phenyl) ethylaminojalkaneamide derivatives of the following formula (I), in particular 2-[2-(3-butoxyphenyl)-ethylamino]-N,N-dimethylacetamide in high...
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WO/2020/198899A1 |
A multifunctional, highly active cationic gemini surfactant and a method for producing the same. The present invention uses a protonic acid, epichlorohydrin, and an organic amine as main raw materials to prepare a series of multifunction...
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WO/2020/202940A1 |
Provided is a catalytic mixture with sufficient catalytic efficiency, wherein pressure loss is small when the catalytic mixture fills a flow reactor and a reactive solution is caused to flow therethrough, and the catalytic efficiency and...
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