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WO/2014/133014A1 |
Provided is a mononuclear ruthenium complex that comprises a ruthenium-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and red...
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WO/2014/133017A1 |
Provided is a mononuclear iron complex that comprises an iron-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and reduction of...
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WO/2014/128198A1 |
The invention relates to bilaterally-substituted tricyclic compounds and pharmaceutical compositions containing them, for use as medicaments. Due to their ability to interact with an internal RNA loop and to mimic a protein a-helix these...
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WO/2014/128545A2 |
The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (lIb); process for its preparation and its conversion to Dolutegravir. The present invention also provides an improved process for the preparation of Dolutegravir (I) or ...
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WO/2014/124892A1 |
The present invention relates to a method for synthesising ionic liquids comprising a carbonate functional group characterized in that it comprises a reaction step A without addition of lithium between a first reactant chosen from an imi...
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WO/2014/118038A1 |
The invention relates to novel phosphorus ligands and to a chemoselective and regioselective method for the hydroaminomethylation of olefins with at least one primary or secondary amine, with the addition of H2 and CO under catalytic con...
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WO/2014/114686A1 |
The invention relates to a method for in-situ conversion of chemically fixed carbon dioxide into low-molecular-weight hydrocarbons by direct heterogeneous catalytic or electrochemical hydration. To this end, carbon dioxide is chemically ...
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WO/2014/111949A1 |
The present invention relates to a simple and commercially feasible preparation of Fingolimod hydrochloride with high purity of greater than 99.9%. The.present invention also provides novel intermediates for the preparation of Fingolimod...
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WO/2014/108671A1 |
A method of preparing a 2,6 disubstituted anilines includes, reacting a 2-amino isophtha!ic acid diester with sufficient Grignard reagent R2CH2MgX to form the corresponding diol product, dehydrating the diol product to the corresponding ...
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WO/2014/101460A1 |
Disclosed are a preparation method of a functionalized choline chloride ionic liquid shown in formula I, and use thereof in an electrochemical energy storage device, as an electrolyte material or an additive used in a lithium ion battery...
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WO/2014/100591A1 |
This disclosure relates to methods for limiting the undesired reverse Mannich reaction during the hydrogenation reduction of one or more nitro functional groups (-NO2) to their corresponding amines (-NH2).
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WO/2014/096648A1 |
The invention relates to a process for continuously producing alkyl acrylate by transesterification reaction between a light alkyl acrylate and a heavy alcohol in the presence of at least one catalyst and of at least one polymerization i...
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WO/2014/090806A1 |
The present invention refers to a process for preparing amines comprising reacting a compound of the formula R1-CO-R2 comprising a carbonyl moiety with a amine compound of the formula HNR3R4 and carbon monoxide in the presence of a catal...
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WO/2014/084185A1 |
Disclosed is a diamine represented by the general formula, a polyimide and polyamide obtained by using the diamine as a raw material, a cyclized product of the diamine, and a method for producing the diamine. In the formula, A is a singl...
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WO/2014/000629A9 |
The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in g...
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WO/2014/069846A1 |
The present invention relates to a method for preparing 1-deoxy-1-(2-hydroxyethyl amino)-D-glucitol from D-glucitol by using a borohydride complex as a reducing agent, and to a method for preparing miglitol from the 1-deoxy-1-(2-hydroxye...
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WO/2014/066713A1 |
A process has been developed for preparing 2-methoxymethyl-1,4-benzenediamine (IV-a), other compounds of formula (IV), and the salts thereof, all of which may be used as primary intermediates in compositions for dyeing keratin fibers.
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WO/2014/066712A1 |
A process has been developed for preparing 2-methoxymethyl-1,4-benzenediamine (IV-a), other compounds of formula (IV), and the salts thereof, all of which may be used as primary intermediates in compositions for dyeing keratin fibers.
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WO/2014/062428A1 |
This invention provides a method for the synthesis of a 2-amino-4,6-dimethoxybenzamide and other benzamides of Compound I: wherein R1, R2, R3, and R4 each independently represent a hydrogen, a C1-C6 alkyl, or a C1-C6 alkoxy; and wherein ...
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WO/2014/061219A1 |
The present invention relates to a 2-(ethylamino)ethanol production method characterized by subjecting N-ethyldiethanolamine to a disproportionation reaction in the presence of at least one catalyst selected from a group consisting of a ...
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WO/2014/056421A1 |
Provided are a 1-cyan-1-(7-methoxyl-1-naphtyl) methanol ester compound, and preparation method and use thereof in the preparation of agomelatine intermediate 2-(7-methoxyl-1-naphtyl) ethylamine. Also provided is an agomelatine preparatio...
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WO/2014/056886A1 |
The present invention relates to electrochemical and optoelectronic devices comprising a cobalt complex operatively connected to a dye-sensitizer comprising at least one thiophene moiety. Also, novel dye-sensitizers, methods of making th...
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WO/2014/054391A1 |
A compound represented by general formula (1). In general formula (1), R1 represents either one of a protective group for a hydroxy group and a hydrogen atom, and R2 and R3 independently represent a protective group for an amino group.
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WO/2014/037962A1 |
Disclosed herein a novel, process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline [(S)-1]. Particularly, the invention relates to the synthesis of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline with ex...
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WO/2014/036865A1 |
The present invention relates to fingolimod mucate, a crystal form A thereof and a preparation method for the fingolimod mucate and the crystal form A thereof. The crystal form A has characteristic peaks in an X-ray powder diffraction pa...
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WO/2014/037444A1 |
Disclosed is a novel process for the reduction of nitro groups to amino derivatives, based on the use of trichlorosilane and an organic base, which is efficient from the chemical standpoint and of wide general applicability.
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WO/2014/032627A1 |
Provided is a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ -amino- δ -biphenyl- a -methylalkanoic acid, or acid e...
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WO/2014/024205A1 |
The present invention is in relation to a method for preparation of (S)-(+)-N, N-dimethyl-[3-(naphthalen-1-yloxy)-1-phenylpropyl]amine or its pharmaceutically acceptable salt and intermediate thereof. The method is industrially viable, e...
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WO/2014/024207A1 |
The invention discloses a novel process for preparation of succinylcholine chloride via transesterification of succinic acid diester with choline chloride.
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WO/2014/016852A1 |
The patent discloses an asymmetric synthesis of (-)-venlafaxine using an organocatalyst via a unified strategy employing organcatalytic Michael addition, regio-selective dehydration and selective epoxide ring opening.
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WO/2014/012832A1 |
The invention concerns a process for the preparation of 2-(3-N,N- diisopropylamino-l-phenylpropyl)-4-hydroxymethyl-phenol and its derivatives, particularly the corresponding (R) 4-trityloxymethyl derivative, useful as intermediate form i...
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WO/2014/013706A1 |
The present invention relates to a method for producing 2-(isopropylamino)ethanol, said method being characterized by comprising carrying out a vapor-phase catalytic reaction of acetone, 2-aminoethanol and hydrogen in the presence of a c...
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WO/2013/093943A9 |
Disclosed herein is a single step catalytic process for the production of enantiomerically pure α-Aryloxy-α'-Azido/Alkoxy alcohols of formula (A). The invention, in particular discloses phenolytic kinetic resolution of racemic anti and...
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WO/2014/005546A1 |
The present invention relates to a preparation method of tapentadol hydrochloride and compounds for preparation of the tapentadol hydrochloride. The preparation method comprises steps using a compound in a formula V or a hydrochloride th...
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WO/2014/007075A1 |
The purpose of the present invention is to inhibit the isomerization from a cis-form of a cationic lipid to a trans-form of the cationic lipid in the production of the cationic lipid, wherein the cationic lipid has at least one methylene...
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WO/2014/001075A1 |
Many optically active amines are valuable pharmaceuticals and intermediates for preparation of active ingredients. Frequently, only one of the two enantiomers is effective and/or harmless, and so the isolation of this enantiomer from the...
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WO/2013/185740A1 |
The invention relates to a method of preparation of 2-amino-2-[2-(4-octylphenyl)- ethyl]propane-1,3-diol (I), comprising opening of the aziridine ring of the intermediates (LVI) by the treatment with organometallic compounds, preferably ...
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WO/2013/182640A1 |
The present invention relates to a process for preparing a compound of formula (I) by reaction between a compound of formula (II) and a compound of formula (III) in the presence of a catalyst comprising copper, of a ligand and of a base....
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WO/2013/182023A1 |
The present invention provides a carbon fiber surface modifier, a modified carbon fiber, composites, and preparation methods therefor. The general structural formula of the carbon fiber surface modifier is as represented by formula (I): ...
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WO/2013/169531A1 |
This invention relates to methods for making oxetan-3-ylmethanamines having the formula (I) wherein R1? and R2? are as defined herein. The methods of the invention provide the compounds of formula (I) in high yields and under conditions ...
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WO/2013/159571A1 |
The present invention relates to a lubricating oil composition and a preparation method therefor. The lubricating oil composition comprises a Mannich base as represented by structural formula (III) and a lubricating oil base oil, where A...
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WO/2013/152548A1 |
The present invention relates to a catalyst for synthesizing ethylene amine and a method for preparing ethylene amine. The catalyst is formed of a main active component, an auxiliary agent, and a carrier processed by ammonification. The ...
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WO/2013/154968A1 |
New stabilizers for solutions of choline hydroxide and related quaternary trialkylalkanolamines are disclosed. The stabilizers are alkyl hydroxylamines, hydrazines, hydrazides, or derivates thereof, including compounds containing more th...
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WO/2013/141262A1 |
Provided are: a liquid-crystal alignment agent that is easy to handle, has excellent coatability, and is capable of forming a liquid-crystal alignment film having photo-alignment properties for vertical alignment; a liquid-crystal alignm...
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WO/2013/141437A1 |
The present invention relates to a method for manufacturing (S)-metoprolol which is used as a depressant, and more specifically, to a novel method for effectively manufacturing high purity (S)-metoprolol, comprising the steps of: carryin...
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WO/2013/132006A1 |
The present invention describes a method for synthesising 2-aminobiphenyls and derivatives thereof. This method can be performed cost-effectively and is based on selective reactions. Functionalised biphenyl compounds are of great interes...
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WO/2013/129682A1 |
Provided is a production method in which a compound comprising an amino group and/or a hydroxyl group is generated under mild conditions by removing atom groups containing CO or CS from a substrate compound containing such atom groups. A...
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WO/2013/121997A1 |
The purpose of the present invention is to provide: a method for obtaining hydrogen or deuterium with high efficiency or hydrogenating or deuterating an organic compound; a device for use in the method; and others. Provided are: a method...
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WO/2013/123153A1 |
The present invention provides nonionic surfactants, compositions incorporating these surfactants, and related methods of making and using such surfactants and compositions. The nonionic surfactants demonstrate excellent equilibrium and ...
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WO/2013/117013A1 |
A new process for the production of APMMEA (aminopropylmethylethanolamine) is proposed. This process comprises at least 2 steps in which MEAPN (monomethylethanolaminopropionitrile) is first produced from MMEA (monomethylethanol amine) an...
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