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Matches 1 - 50 out of 10,772

Document Document Title
WO/2019/041961A1
Provided are a transparent nucleating agent, a preparation method therefor and the use thereof, wherein the transparent nucleating agent comprises a compound represented by formula (1) and a derivative thereof; the method comprises: brin...  
WO/2019/035775A1
A method for the preparation of tapentadol in the form of a base or its hydrogen chloride, which involves the preparation of a salt (III) from a mixture of diastereomers (II) by means of crystallization-induced asymmetric transformation ...  
WO/2019/020889A1
The present invention relates to the production of (meth)acrylic esters according to a continuous process by transesterification, and in particular to the purification of a crude reaction mixture comprising a C4-C12 (meth)acrylic ester w...  
WO/2019/020466A1
Process for the hydrolysis or alcoholysis of a ketal or acetal compound wherein a ketal or acetal compound comprising at least one ketal or acetal group and at least one amino group is reacted with carbon dioxide and water oran alcohol.  
WO/2019/020488A1
Process for the preparation of a compound of formula (I) with R1 and R2 independently from each other representing hydrogen or a C1-to C10 alkyl group by a two-step process wherein the first step is an amination of the compound of formul...  
WO/2019/009412A1
The present invention addresses the problem of providing a novel compound having high LSD1 inhibitory activity, high selectivity for LSD1 inhibition, and/or having useful therapeutic effects for various diseases. One embodiment of the pr...  
WO/2019/001549A1
A multi-arm single molecular weight polyethylene glycol and an active derivative thereof, used for drug modification, effectively improving the solubility, stability, and immunogenicity of drugs; improving the absorption of the drugs in ...  
WO/2019/001473A1
Provided are a dendritic polyglycol derivative, a preparation method therefor, and an application thereof. The dendritic polyglycol derivative has a structure of formula (I), a plurality of terminal functional groups, and better water so...  
WO/2018/234294A1
The present invention relates to a fabric softener active composition comprising: a component (a), said component being at least one or a mixture of quaternary mono-, di- or tri-ester ammonium compounds; a component (b), said component b...  
WO/2018/228981A1
The invention relates to a process for the preparation of a compound represented by formula (I) wherein X is selected from the group consisting of -H, -halogen, linear or branched C1-C7 alkyl group, linear or branched C1-C5 alkoxy group,...  
WO/2018/224315A1
The invention relates to a method for producing alkanolamines and/or ethyleneamines in the liquid phase by reacting ethylene glycol and/or monoethanolamine with ammonia in the presence of an amination catalyst which contains one or more ...  
WO/2018/224316A1
The invention relates to a method for producing alkanolamines and/or ethyleneamines in the liquid phase, by reacting ethylene glycol and/or monoethanolamine with ammonia in the presence of an amination catalyst containing Co, Ru and Sn.  
WO/2018/224321A1
The invention relates to a method for producing alkanolamines and/or ethyleneamines in the liquid phase, by reacting ethylene glycol and/or monoethanolamine with ammonia in the presence of an amination catalyst obtained by reducing a cat...  
WO/2018/223347A1
Disclosed is a method for synthesizing an N-alkylaminophenyl alkyl ether, wherein the N-alkylaminophenyl alkyl ether is prepared by subjecting a nitrophenyl alkyl ether to hydrogenation reduction and alkylation, or wherein same may also ...  
WO/2018/214877A1
Disclosed is a crystal form of dezocine. The X-ray powder diffraction (XRD) pattern thereof is determined using Cu/K-α1, and has a diffraction peak at the 2θ value of 9.1±0.2 and 12.2±0.2, and the height% of these diffraction peaks a...  
WO/2018/209665A1
A preparation method for a nano-nickel-based catalyst with a confinement structure and hexahedral morphology. According to the method, a nickel-aluminum hydrotalcite precursor of an organic carbon chain intercalation is synthesized first...  
WO/2018/205108A1
Provided is a method for the alcoholysis of an amide. The method comprises subjecting an amide-containing compound to alcoholysis under alkaline conditions using an epoxy compound as an accelerator. The method described above is easy to ...  
WO/2018/202765A1
The present invention relates to a process for the conversion of ethylene oxide to 2-aminoethanol and/or ethane-1,2-diamine and/or linear polyethylenimines of the formula H2N- (CH2CH2NH)n-CH2CH2-NH2 wherein n≥ 1 comprising (i) providin...  
WO/2018/195956A1
Provided is a method for preparing a single crystal of an anhydrous halogenated choline or a derivative thereof, comprising the steps of: (1) proportionally weighing the halogenated choline or a derivative thereof, an alcohol or ether co...  
WO/2018/199166A1
The purpose of the present invention is to provide: compounds having a TrkA inhibiting effect, or pharmacologically acceptable salts thereof, or solvates of these; pharmaceutical compositions characterized by containing these as an activ...  
WO/2018/172026A1
The invention relates to a process for synthesizing an aqueous N,N-dimethyl glucamine solution, characterized in that a formaldehyde solution is metered into an N-methyl glucamine solution in the presence of a metal catalyst at hydrogen ...  
WO/2018/172025A1
The invention relates to a method for preparing aqueous solutions of N,N-dimethylglucamine, characterized by first preparing an adduct of N-methylglucamine and formaldehyde in water at temperatures of between 15°C and 40°C, and subsequ...  
WO/2018/174442A1
The present invention relates to a compound for treating diseases caused by a coronavirus infection. The compound exhibits excellent inhibitory activity against coronaviruses, and is useful as a pharmaceutical composition for preventing ...  
WO/2018/148113A1
The present invention is directed to 13C and/or 2H isotope enhanced ambroxol ("isotope enhanced ambroxol") and its use in the treatment of autophagy infections, especially mycobacterial and other infections, disease states and/or conditi...  
WO/2018/146529A1
The present invention relates to a high yield process of preparation of, [1-[2-(Dimethylamino)-1- (4-hydroxyphenyl)ethyl]-cyclohexanol]through potassium hydroxide mediated demethylation of [1-[2-(Dimethyl amino-1-(4-methoxyphenyl) ethyl ...  
WO/2018/144101A1
Described herein are labeling agents, specifically [11C]fluoroform, [11C]difluoromethane, [11C]fluoromethyl iodide, [11C]fluoromethyl bromide, [11C]fluoromethyl chloride, [11C]fluoromethyl trifluoromethansulfonate, [11C]difluoromethyl io...  
WO/2018/135506A1
The purpose of the present invention is to provide a ruthenium complex which is capable of serving as a reduction catalyst that is applicable to an industrial production. According to the present invention, ketones, aldehydes, esters or ...  
WO/2018/127806A1
The present invention provides a process for preparation of isoproterenol hydrochloride (1a) comprising catalytic hydrogenation of 3',4'-dihydroxy-2-(isopropylamino)-acetophenone hydrochloride (5a) in presence of an ion exchange resin, t...  
WO/2018/126040A1
The present invention is generally directed to crystalline forms of (1S,3S,4R)-4-((3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-me thyleneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcy clohexanol and processes for their preparation.  
WO/2018/124148A1
The purpose of the present invention relates to providing a novel glyceric acid ester which can be produced at a high yield and for which use as a synthesis intermediate can be expected, and a method for producing same. The purpose of th...  
WO/2018/124149A1
The purpose of the present invention is to provide a method for producing glyceric acid ester that enables easy, high-yield production and makes it easy to reuse pyridines that are used for a reaction. Provided is a method for producing ...  
WO/2018/124147A1
The present invention relates to a method for manufacturing 1,3-dioxane-5-ones by a short and simple method from raw materials that can be obtained easily and inexpensively, using 1,3-dioxane, which is a mixture with 1,3-dioxalans, as a ...  
WO/2018/108888A1
The invention pertains to a process for preparing hydroxyethyl ethylene amines and/or ethylene urea derivatives thereof comprising the step of reacting monoethylene glycol with an amine-functional compound comprising at least two -NH- un...  
WO/2018/108698A1
The invention relates to a method for producing ethanolamines and/or ethyleneamines in the gas phase by reacting ethylene glycol with ammonia in the presence of an amination catalyst. The method is characterized in that the amination cat...  
WO/2018/104677A1
The subject of the invention is a process for continuously producing a (meth)acrylic ester by transesterification reaction between a light C1-C4 alkyl (meth)acrylate and a heavy alcohol in the presence of a catalyst, characterized in tha...  
WO/2018/104176A1
The invention relates to a method for producing farnesyl amines by reacting ß-farnesene with one or more amines in the presence of a transition metal catalyst of the10th subgroup, at a temperature in the region of between 60 - 150 °C. (I)  
WO/2018/098799A1
The present invention relates to a process for preparing a polyurethane foam by reacting a polyisocyanate with a polyol in the presence of a blow agent and a particular family of amine. The present invention also relates to a polyurethan...  
WO/2018/084625A1
The present invention relates to a novel method for preparing (S)-N1-(2-aminoethyl)-3-(4-alkoxyphenyl)propane-1,2-diamine trihydrochloride.  
WO/2018/044982A1
A process for preparing a silver-containing catalyst for the selective oxidation of ethylene to ethylene oxide including the steps of: (a) providing a multimodal support, (b) preparing an impregnation solution comprising a silver compone...  
WO/2018/032522A1
A supported catalyst used for synthesizing a polyether amine, and a manufacturing method of the catalyst. The catalyst comprises: a porous oxide as a support; Ni, Cu, Pd, and Rh as an active component; and one or more of any of Zr, Cr, M...  
WO/2018/028679A1
A post-processing method for a Mirabegron intermediate, comprising the following steps: with a Mirabegron carbonyl of formula I serving as a reaction raw material, the carbonyl therein is reduced via a reduction reaction under the effect...  
WO/2018/021517A1
The present invention relates to a 4-alkoxy-3-(trifluoromethyl)benzyl alcohol production method with which it is possible to achieve a higher conversion rate and to closely control the generation of by-products by using DIBAL as a reduci...  
WO/2018/020380A1
The present invention provides process for preparation of enantiomerically pure (R)-3- aminobutan-1-ol (I) by treating 4-hydroxybutan-2-one (II) with transaminase enzyme and use of enantiomerically pure (R)-3-aminobutan-1-ol (I) in the p...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/207839A1
The invention relates to a method for obtaining β-amino alcohols, in which the following steps are performed using amines and a diol/water mixture: adding a catalytic mixture to the starting amine; next, adding the diol/water mixture; s...  
WO/2017/206692A1
An organic amine salt compound having the general formula (I): An-[Bm+]p. In the formula, An- is anions having -n valence serving as CO2 donors, wherein n = 1, 2, or 3; Bm+ is or contains: ammonium ions and/or organic amine B cations; m ...  
WO/2017/206693A1
An organic amine salt compound having the general formula (I): An-[Bm+]p. In the formula, An- is anions having -n valence serving as CO2 donors, wherein n = 1, 2, or 3; Bm+ is or contains: ammonium ions, hydrazine ions and/or organic ami...  
WO/2017/209235A1
The present invention addresses the problem of providing a low-cost and highly-safe method for producing a polycyclic aromatic aminophenol compound in a small number of steps. The method for producing a polycyclic aromatic aminophenol co...  
WO/2017/193913A1
Provided are a fosaprepitant phosphate intermediate (IV) preparation method, a fosaprepitant phosphate intermediate (IV-A) and a method (AA) for preparing fosaprepitant dimeglumine by using the intermediate (IV-A). IV: R1 and R2 are inde...  
WO/2017/187067A1
The invention relates to the use of 2,6-di-tert-butyl-4-methylphenol at a moiety of 25 to 200 ppm for stabilizing N,N-dimethylaminoethyl acrylate in respect of discoloring effects. The invention also relates to an N,N-dimethylaminoethyl ...  

Matches 1 - 50 out of 10,772