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Matches 1 - 50 out of 7,658

Document Document Title
WO/2018/009720A1
Methods and compounds for use in promoting survival of at least one eukaryotic cell, wherein the compounds are effective as gamma-ketoaldehyde scavengers.  
WO/2018/000098A1
A method of treating an inflammatory myopathy includes topically administering to the skin of an individual with the inflammatory myopathy a composition comprising R-salbutamol, a physiologically acceptable derivative thereof, or a pharm...  
WO/2018/004945A1
A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):  
WO/2017/218886A1
The invention relates to compounds, compositions and methods for activating, reactivating, reversing or preventing the deactivation of cholinesterases, such as acetylcholinesterase and butyrylcholinesterase.  
WO/2017/214680A1
The present invention relates to new multi-functional compounds that are useful in the treatment of neurodegenerative diseases, such as Alzheimer's disease, to the preparation of the compounds, and to compositions including the compounds...  
WO/2017/215592A1
The present disclosure provides co-crystals of a lithium benzoatecompound and a co-former compound of Formula (I). Also provided herein are methods of preparing the co-crystals and uses thereof in treating and/or reducing the risk for a ...  
WO/2017/212007A1
Compositions for nucleic acid delivery are provided which comprise a relatively low amount a permanently cationic lipid or lipidoid, such as a lipid comprising a quaternary ammonium group. The compositions are suitable for the delivery o...  
WO/2017/214334A1
Disclosed herein are lignin-derived ionic liquids and methods for preparing them. The methods include forming a reaction mixture comprising a lignin-derived starting material, a carbonyl compound, and an amine; maintaining the reaction m...  
WO/2017/212009A1
A composition for the delivery of a nucleic acid compound is provided which comprises a cationic peptide or polymer and a lipidoid compound. The nucleic acid compound may be any chemically modified or unmodified DNA or RNA. The amount of...  
WO/2017/207839A1
The invention relates to a method for obtaining β-amino alcohols, in which the following steps are performed using amines and a diol/water mixture: adding a catalytic mixture to the starting amine; next, adding the diol/water mixture; s...  
WO/2017/206692A1
An organic amine salt compound having the general formula (I): An-[Bm+]p. In the formula, An- is anions having -n valence serving as CO2 donors, wherein n = 1, 2, or 3; Bm+ is or contains: ammonium ions and/or organic amine B cations; m ...  
WO/2017/206693A1
An organic amine salt compound having the general formula (I): An-[Bm+]p. In the formula, An- is anions having -n valence serving as CO2 donors, wherein n = 1, 2, or 3; Bm+ is or contains: ammonium ions, hydrazine ions and/or organic ami...  
WO/2017/209235A1
The present invention addresses the problem of providing a low-cost and highly-safe method for producing a polycyclic aromatic aminophenol compound in a small number of steps. The method for producing a polycyclic aromatic aminophenol co...  
WO/2017/197014A3
Compositions comprising a polymeric dye and a cyclodextrin are provided. Methods associated with preparation and use of such compounds, for example in methods for detection of any analyte molecule, are also provided.  
WO/2017/197014A2
Compositions comprising a polymeric dye and a cyclodextrin are provided. Methods associated with preparation and use of such compounds, for example in methods for detection of any analyte molecule, are also provided.  
WO/2017/193913A1
Provided are a fosaprepitant phosphate intermediate (IV) preparation method, a fosaprepitant phosphate intermediate (IV-A) and a method (AA) for preparing fosaprepitant dimeglumine by using the intermediate (IV-A). IV: R1 and R2 are inde...  
WO/2017/185261A1
The present invention relates to the technical field of medicine, and provides mosapride active metabolites (R)-N-[2-hydroxy-3-(4-fluorobenzyl)amino]propyl-5-chloro-4-a mino-2-ethoxy benzamide (levo isomer) and (S)-N-[2-hydroxy-3-(4-fluo...  
WO/2017/182438A1
The present invention relates to tapentadol phosphate in crystalline form and to a process for producing tapentadol phosphate in crystalline form. Further,the present invention relates to a composition comprising crystalline tapentadol p...  
WO/2017/177065A3
Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, L1, L2, L3, L4, M, m and n are as defined herein. Meth...  
WO/2017/177065A2
Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, L1, L2, L3, L4, M, m and n are as defined herein. Meth...  
WO/2017/173355A1
Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, L1, L2, L3, L4, M, m and n are as defined herein. Meth...  
WO/2017/173348A1
Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, L1, L2, L3, L4, L5, A, M, m and n are as defined herei...  
WO/2017/159814A1
The present invention provides a method for producing ethanolamines whereby it is possible to keep the yield of dialkanolamines low (for example, less than 30% by weight). This method for producing alkanolamines involves reacting an alky...  
WO/2017/152083A1
Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.  
WO/2017/149052A1
The invention pertains to a process for producing a compound of formula (11) wherein R7 and R8 are each independently selected from H, halogen, alkyl, aryl, or alkylaryl, R42 is H or a protective group, R43 is H or R3, wherein R3 is a pr...  
WO/2017/141775A1
The present invention relates to a lubricant containing an ionic liquid that has a conjugate base and a conjugate acid, wherein the conjugate acid has a group including a hydroxyl group and a group including a linear hydrocarbon group ha...  
WO/2017/137990A1
A new family of mononuclear organometallic complexes of a divalent metal bound to sequential tetradentate monoanionic {ONNN}-type ligands, and polymerization of cyclic esters such as lactides utilizing same are provided. Novel tetradenta...  
WO/2017/136976A1
The present invention discloses an ionic liquid having a methanofullerene carboxylate as an anion, and a preparation method thereof. The ionic liquid is comprised of the methanofullerene carboxylate anion and a quaternary ammonium cation...  
WO/2017/134841A1
The present invention provides: a liquid crystal display element that is highly reliable, has improved various characteristics as a liquid crystal display element, and in which dropping marks do not readily occur during production, witho...  
WO/2017/134190A1
Herein is reported a deep eutectic solvent consisting of (2-hydroxyethyl) trimethyl ammonium chloride and dithiothreitol in a molar ratio of from 1:2 to 1:3 and of from 0 % to 10 % co-solvent.  
WO/2017/118375A1
Disclosed in the present invention is a Dezocine analogue, and particularly disclosed are compounds represented by formula (I), (II) and (III), a pharmaceutically acceptable salt or tautomer thereof.  
WO/2017/115256A1
A method of reducing color in an alkanolamine, the method comprising: contacting the alkanolamine with an amount of an aqueous solution effective to provide 5 to 1000 parts per million by weight of an alkali metal borohydride, based on p...  
WO/2017/102659A1
The invention relates to a method for synthesising at least one nitrogen compound belonging to the family of the partially N-hydroxyethylated tertiary 1,6-hexanediamines of the following general formula (I) in which the groups R1, R2 and...  
WO/2017/102746A1
The invention relates to an absorbent solution, and to a method for implementing said solution, for eliminating acid compounds contained in a gaseous effluent, comprising water and at least one diamine of general formula (I), in which: t...  
WO/2017/100856A1
The present invention relates to a novel dendrimer. The present invention also relates to formulations comprising the dendrimer with improved characteristics. For instance, the present invention relates to formulations comprising pestici...  
WO/2017/106861A1
The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetyla...  
WO/2017/104591A1
The purpose of the present invention is to provide an n-type thermoelectric conversion layer having a high power factor and excellent performance stability, a thermoelectric conversion element equipped with the n-type thermoelectric conv...  
WO/2017/098408A1
A method of reducing color in an alkanolamine is described. The method includes contacting the alkanolamine with a color-reducing amount of a borane complex effective to provide a color-reduced alkanolamine composition having a Platinum-...  
WO/2017/095677A1
A process for synthesizing 2-methoxymethyl-l,4-benzenediamines which comprises a radical halogenation step of compounds of formula (II) to compounds of formula (III). The final product can be 2-methoxymethyl-l,4-benzenediamine useful as ...  
WO/2017/093209A1
The present invention relates to a process for preparing 3-amino tetrahydropyrans and, more particularly, to an improved method for synthesizing a 2,3,5-substituted tetrahydropyran derivative, intermediate being used in the preparation o...  
WO/2017/085734A1
The present invention relates to crystalline forms of Tapentadol salts and process for preparation thereof. The structural formula of Tapentadol salts is represented as follows: [Formula should be inserted here].  
WO/2017/081590A1
The present invention provides a process for preparing omarigliptin.  
WO/2017/075145A1
The present invention provides novel compounds that are quinoline foldamers. Such foldamers stabilize and bind to islet amyloid polypeptide (IAPP). In certain embodiments, the quinoline foldamers of the invention are soluble and cross bi...  
WO/2017/062704A1
The invention provides compositions and methods for treating pancreatitis, fistulae, leaks or pseudocysts in a patient comprising administering to the patient an effective amount of a hydroxypolyamine (also referred to herein as a "polya...  
WO/2017/035879A1
The present invention provides a method for preparing single-layer metal phosphate and applications thereof. The method comprises: (1) carrying out intercalation treatment on layered metal phosphate by means of alkylol amine, so as to ob...  
WO/2017/036357A1
Provided are a cathepsin K inhibitor and application thereof, and specifically is a compound having a structure represented by formula (I) and being used to treat or prevent a cathepsin dependent disease. In particular, the cathepsin is ...  
WO/2017/033212A1
The invention provides a process for preparing sacubitril. The present invention also provides a novel salt of sacubitril and its crystalline form. The invention further provides crystalline N-(3-carboxy-1- oxopropyl)-(4S)-(p-phenylpheny...  
WO/2017/024009A1
β-Substituted β-amino acids, β-substituted β-amino acid derivatives, and β-substituted β-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The β-substituted β-amino acid derivatives and...  
WO/2017/015760A1
The present disclosure relates to compositions and combinations comprising one or more insulin(s) and one or more vasoactive agent(s), and use thereof for increasing subcutaneous insulin absorption and/or treating diabetes and/or treatin...  
WO/2016/209628A1
This disclosure describes a low temperature process for the preparation of tertiary amines from nitriles and secondary amines via reductive amination using transfer hydrogenation. The process can use a nitrile and a dialkylamine and proc...  

Matches 1 - 50 out of 7,658