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Matches 1 - 50 out of 7,989

Document Document Title
WO/2020/178085A1
The present invention relates to a process for preparing alkanolamines and ethyleneamines in the liquid phase, by reacting ethylene glycol and/or monoethanolamine with ammonia in the presence of an amination catalyst which is obtained by...  
WO/2020/172075A1
Disclosed herein are novel solid forms of FXR agonist of Formula (I). The disclosure also relates to pharmaceutical compositions containing one or more of the solid forms disclosed herein, as well as methods of using the solid forms in t...  
WO/2020/165338A1
The invention pertains to a process for manufacturing ethyleneamine compounds selected from the group of ethyleneamines and hydroxyethylethyleneamines wherein the process comprises two reaction sequences, the first reaction sequence comp...  
WO/2020/165330A1
Process for manufacturing ethyleneamine compounds selected from the group of ethyleneamines and hydroxyethylethyleneamines wherein the process comprises two reaction sequences, the first reaction sequence comprising the steps of: - in an...  
WO/2020/162408A1
The present invention has the effect of making it possible to produce 1,1,1-trifluoro-2,2-bisarylethane efficiently by a simple procedure by condensing a mixture of fluoral and hydrogen fluoride with an aryl compound under anhydrous cond...  
WO/2020/156522A1
Provided are a dezocine derivative of formula I or a tautomer, optical isomer, oxynitride, solvate, pharmaceutically acceptable salt or prodrug thereof, and a pharmaceutical composition comprising the same, a preparation method therefor,...  
WO/2020/154731A1
Novel salicylamine derivatives are targeted directly to the mitochondria to increase effectiveness and lower required dosages in the treatment of conditions caused by inflammation or oxidative stress.  
WO/2020/153005A1
A composite amine absorption solution according to the present invention is an absorption solution capable of absorbing CO2 or H2S or both of them in a gas, and is prepared by dissolving (1) a linear monoamine, (2) a diamine and (3) a co...  
WO/2020/147160A1
The present invention belongs to the technical field of pharmaceutical chemistry, and specifically relates to a method for preparing fosfomycin trometamol, the method comprising the following steps: 1) adding fosfomycin diamino butantrio...  
WO/2020/084599A3
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/089942A3
A liquid injectable composition comprising (a) at least one surfactant; (b) at least one gel strength enhancer; (c) at least one solvent; (d) optionally release retarding agent(s); (e) optionally stabilizing agent(s); (f) optionally phar...  
WO/2020/132819A1
Disclosed is a method for preparing (1R,3S)-3-aminocyclopentanol hydrochloride. The method comprises using amide formed by chiral carboxylic acid and hydroxylamine as a chiral source, quickly obtaining a chiral Diels-Alder reaction produ...  
WO/2020/120637A1
The application relates to a compound of formula (I) or a pharmaceutical salt thereof of formula (II), as well as to a process to obtain said compound and a process to obtain said salt. Additionally disclosed is the compound of formula (...  
WO/2020/118307A1
This disclosure provides compositions of SALTAME core containing compounds and associated methods for use in tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related me...  
WO/2020/107913A1
The present invention discloses a compound shown in a formula I or a salt thereof, wherein R1 is selected from hydrogen, hydroxyl, C1-6 alkyl, substituted C1-6 alkyl, halogen, amino and thiol wherein the substituted C1-6 alkyl group is s...  
WO/2020/106903A1
The compounds disclosed herein compound of Formula (I), substructures thereof, and pharmaceutically acceptable salts thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a...  
WO/2020/093657A1
Disclosed is a method for preparing 4,6-diamino resorcinol hydrochloride, which belongs to the organic chemical synthesis field. The method comprises: using a Bronsted acid and acetic anhydride as a new dioxime Beckmann rearrangement rea...  
WO/2020/089934A1
This invention relates to methods for racemization of dextro-rotatory ephedrine via enzymatic kinetic conversion, and is particularly useful for conversion of dextro- rotatory ephedrine (d- ephedrine) to racemic mixture of dextro-rotator...  
WO/2020/084599A2
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/071935A1
The present invention relates to choline salts of fumaric acid for use as ingredients in dietary supplements, in medical nutrition, and in pharmaceutical compositions for the prevention and treatment of diseases caused by hypoxia.  
WO/2020/055507A1
Aprotic-protic ionic salt (APS) compositions and methods of using aprotic-protic ionic salt compositions to stabilize nucleic acids at ambient temperatures are provided. Certain aspects provide aprotic-protic ionic salt compositions for ...  
WO/2020/046515A1
The present disclosure provides a quaternary ammonium hydroxide solution comprising a reaction product of a polyamine and an organic oxirane. The quaternary ammonium hydroxide solution may be used in various applications, such as in remo...  
WO/2020/047035A1
The present disclosure provides, inter alia, methods of treating cancer by administering an effective amount of a compound of Formula (I). In some embodiments, the cancer is a solid cancer. In some embodiments, the cancer is melanoma. In...  
WO/2020/042841A1
A preparation method for (1R,3S)-3-amino-1-cyclopentanol and salts thereof, relating to the field of organic synthesis, wherein the (1R,3S)-3-amino-1-cyclopentanol undergoes an asymmetric cycloaddition reaction with cyclopentadiene by us...  
WO/2020/032080A1
Provided is a compound represented by general formula (I), or a salt thereof. (In the formula, X1, X2, X3 and X4 are a hydrogen atom, a C1-9 alkyl group, or a C3-9 unsaturated hydrocarbon group which has 1-4 triple bonds between carbon a...  
WO/2020/029846A1
Disclosed by the present invention is a rapid synthesis method for a biomass-based amine compound, comprising: by using formamide as an amine source, using formic acid as a hydrogen source, and using biomass aldehydes and ketones as raw ...  
WO/2020/028322A1
Improvements in catalyst systems and associated processes for the conversion of glycolaldehyde to monoethanolamine are disclosed. The catalyst systems exhibit improved selectivity to this desired product and consequently reduced selectiv...  
WO/2020/025444A1
Object of the present invention is a better crystalline form of Eltrombopag (ETP) monoethanolamine salt, named Form D, stable, suitable for pharmaceutical purposes, and with the highest solubility in water and excellent non-hygroscopicit...  
WO/2020/025789A1
The present invention relates to salts of elafibranor.  
WO/2020/028262A1
Improvements in catalysts and associated processes for the conversion of glycolaldehyde to diethanolamine are disclosed. The catalysts exhibit improved selectivity to this desired product and consequently reduced selectivity to monoethan...  
WO/2020/014596A1
Described are compositions and methods for inhibiting polymerization of a monomer (e.g., styrene) composition, which use an N-O polymerization inhibitor, a quinone methide polymerization retarder, and an amine stabilizer having a primary...  
WO/2020/014606A1
Described are compositions and methods for inhibiting polymerization of a monomer (e.g., styrene) composition a quinone methide polymerization retarder and an oxygen-containing amine compound that is a tertiary amine or hydroxylamine. In...  
WO/2020/010055A1
A process for the preparation of amino alcohols includes condensing a compound of Formula (II), a stereoisomer, a tautomer, or a salt thereof with a compound of Formula (IlIa) or Formula (Illb), a stereoisomer, a tautomer, or a salt ther...  
WO/2020/000172A1
The present invention relates to a process for producing an esterquat by a transesterification reaction of a fatty acid oil or a mixture comprising one or more fatty acid oils and one or more fatty acids with a tertiary hydroxy amine and...  
WO/2020/005313A1
The invention provides methods and compositions for treating cancers and myeloproliferative disorders using sphingosine kinase-1 inhibitors, such as SK1-I, and selective sphingosine-1-phosphate receptor agonists, such as ozanimod.  
WO/2019/238965A1
The present invention relates to several novel 1-O-glycosylated sphingoid bases and to a production method thereof, as well as to uses of the 1-O-glycosylated sphingoid bases. Sphingoid bases carrying a vinylogous amide-type protecting g...  
WO/2019/238970A1
The present invention relates to sphingolipids, and more particularly to a method for the production of sphingoid bases, especially sphingosine, and novel derivatives thereof. The sphingoid bases are herein produced by making use of a vi...  
WO/2019/229156A1
The present invention relates to a process for the conversion of ethylene oxide to 2- aminoethanol and/or Di(2-hydroxyethyl)amine comprising (i) providing a catalyst comprising a zeolitic material comprising YO2 and X2O3 in its frame- wo...  
WO/2019/219942A1
Provided is a process for producing an amine via a hydroaminoalkylation reaction of a non-aromatic C-C double bond or C-C triple bond, said process comprising a step of reacting a compound comprising a non-aromatic C-C double bond or C-C...  
WO/2018/227012A9
The present invention provides compositions (e.g., nanoparticles) comprising a conjugated polyethyleneimine (PEI) polymer (a "conjugated lipomer"), or a pharmaceutically acceptable salt thereof, and a lipid-PEG conjugate, wherein the con...  
WO/2019/207701A1
A composition comprising a) a quarternary trialkylalkanolamine hydroxide and b) at least one diamine as component b), which is selected from the group consisting of 1-amino-4-methylpiperazine, 1,2-diaminopropane and mixtures thereof.  
WO/2019/198023A1
Subject-matter of the present invention is a process for the preparation of optically active phenyl-beta-amino alcohols by means of a specific reduction of the corresponding phenyl-beta-amino ketones. Further subject-matter of the invent...  
WO/2019/196263A1
The present invention relates to the field of pharmaceutical synthesis, in particular to a method for preparing a hexahydrofuro-furanol derivative, an intermediate thereof and a preparation method therefor. The preparation method compris...  
WO/2019/197359A1
The present invention relates to a new method of making phenalkamines, products produced by such method, and use of such products. The method provides for phenalkamines obtained by an amine exchange reaction of a cardanol derived Mannich...  
WO/2019/193117A1
A two-step one-pot process for reacting glycolaldehyde with an aminating agent in the presence of a reactive organic fluid for instance a reactive solvent is provided. The first step comprises of contacting glycolaldehyde with an aminati...  
WO/2018/227012A8
The present invention provides compositions (e.g., nanoparticles) comprising a conjugated polyethyleneimine (PEI) polymer (a "conjugated lipomer"), or a pharmaceutically acceptable salt thereof, and a lipid-PEG conjugate, wherein the con...  
WO/2019/192903A1
The invention relates to a method for producing specific amines, wherein, in a first step, a corresponding amino alcohol is reacted with a suitable carbonyl compound and subsequently, in a second step, the intermediate obtained in the fi...  
WO/2019/189717A1
Provided is a novel method for producing a compound represented by formula (I). The invention according to the present application provides: a method for producing a compound represented by formula (I); and methods respectively for produ...  
WO/2019/163732A1
The present invention addresses the problem of providing a novel squarylium dye which enables a coloring resin composition to achieve chromaticity values equivalent to those of coloring resin compositions that contain conventional squary...  
WO/2019/158719A1
A process is provided for the production of bis-choline tetrathiomolybdate, the process comprising reacting a choline salt with ammonium tetrathiomolybdate, wherein the choline salt is a hydroxide, acetate, or halide choline salt, wherei...  

Matches 1 - 50 out of 7,989