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Matches 1 - 50 out of 10,192

Document Document Title
WO/2019/009412A1
The present invention addresses the problem of providing a novel compound having high LSD1 inhibitory activity, high selectivity for LSD1 inhibition, and/or having useful therapeutic effects for various diseases. One embodiment of the pr...  
WO/2019/008156A1
The present invention provides novel compounds of formula (I) that are useful as inhibitors of the PD-1/PD-L1 protein/protein interaction. The compounds may be used in the treatment of cancer, infectious diseases and neurodegenerative di...  
WO/2019/001473A1
Provided are a dendritic polyglycol derivative, a preparation method therefor, and an application thereof. The dendritic polyglycol derivative has a structure of formula (I), a plurality of terminal functional groups, and better water so...  
WO/2018/230848A1
The present specification relates to a compound in chemical formula (1), a coating composition comprising the compound in chemical formula (1), an organic light-emitting device using same and a method for preparing same.  
WO/2018/223347A1
Disclosed is a method for synthesizing an N-alkylaminophenyl alkyl ether, wherein the N-alkylaminophenyl alkyl ether is prepared by subjecting a nitrophenyl alkyl ether to hydrogenation reduction and alkylation, or wherein same may also ...  
WO/2018/219204A1
The present invention relates to a novel phenoxyacetic acid derivative represented by general formula (I), a preparation method for the derivative and uses of drug compositions containing the derivative in drug preparation for treatment ...  
WO/2018/211844A1
This compound is represented by general formula (1). In general formula (1), R1 and R2 are each independently an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, an aryl group having 6 to 14 carbon atom...  
WO/2018/213140A1
Disclosed herein are compounds of Formulae (la), (lb), (Ic), (Id), (le), (If), (Ig), (Ih), (Ik), (Im), (In), (Io), (Ip), (Iq), (Ir), (Is) and (It), methods of synthesizing compounds of Formulae (la), (lb), (Ic), (Id), (le), (If), (Ig), (...  
WO/2018/213281A1
The present disclosure relates to novel compounds, pharmaceutical compositions containing the compounds and methods of using the compounds and pharmaceutical compositions for treating neurodegerative diseases, including Alzheimer's disea...  
WO/2018/210738A1
An absorbent for the selective removal of hydrogen sulfide from a fluid stream comprising carbon dioxide and hydrogen sulfide, wherein the absorbent contains an aqueous solution, comprising:a) an amine or a mixture of amines of the gener...  
WO/2018/207120A1
The present invention is directed towards a process for the preparation of 4- fluoro-2-methoxy-5-nitroaniline (I) or salts thereof, wherein, 4-fluoro-2-methoxy aniline (III) is protected to obtain N-protected-(4-fiuoro-2-methoxy)aniline ...  
WO/2018/202681A1
The invention is in the technical field of insect control and relates to the use of a disubstituted benzenes for controlling insecticide-resistant pests such as mosquitoes and cockroaches.  
WO/2018/186040A1
Provided is an ionic liquid, characterized in containing a cationic component and an anionic component, and in that the cationic component comprises a group having a perfluoropolyether chain and a group having a hydroxyl group.  
WO/2018/174442A1
The present invention relates to a compound for treating diseases caused by a coronavirus infection. The compound exhibits excellent inhibitory activity against coronaviruses, and is useful as a pharmaceutical composition for preventing ...  
WO/2018/167264A1
The present invention relates to a phenalene-1-one compound, a photosensitizer composition comprising said phenalene-1-one compound, an article comprising said phenalene-1-one compound and/or photosensitizer composition and the use thereof.  
WO/2018/159933A1
The present specification relates to a fluorine-based compound in chemical formula (1), a coating composition comprising the fluorine-based compound in chemical formula (1), an organic light-emitting device using same and a method for pr...  
WO/2018/158674A1
The present invention is in relation to a process of preparation of asymmetric synthesis of Rivastigmine and its salts in high yield and purity.  
WO/2018/159937A1
The present specification relates to a fluorine-based compound in chemical formula (1), a coating composition comprising the fluorine-based compound in chemical formula (1), an organic light-emitting device using same and a method for pr...  
WO/2018/143923A1
The present disclosure is drawn to an amine synergist including a tertiary benzylamine with a substituted benzene ring attached to a tertiary amine. The tertiary amine can be modified with multiple water soluble groups.  
WO/2018/137558A1
The present disclosure relates to materials with strong circular dichroism (CD), circularly polarized luminescence (CPL), and high fluorescence quantum yield in the aggregate state and methods of preparation and use thereof.  
WO/2018/122359A1
The present invention relates to a compound of the following formula (I). The invention also relates to uses thereof as a chromophore as such or for building pigments displaying special optical effects, including metal-like reflection.  
WO/2018/119356A1
Methods for inhibiting transepithelial ion transport, inhibiting hydrocephalic development, and for treating hydrocephalus are disclosed herein. The methods include administering a potassium channel inhibitor to the individual. In one pa...  
WO/2018/108992A2
The present invention relates to compounds of the formula (I), in particular to phenoxyphenylamidines of the formula (I), to a process for their preparation, to the use of phenoxyphenylamidines of the formula (I) according to the inventi...  
WO/2018/108992A3
The present invention relates to compounds of the formula (I), in particular to phenoxyphenylamidines of the formula (I), to a process for their preparation, to the use of phenoxyphenylamidines of the formula (I) according to the inventi...  
WO/2018/107158A1
This present disclosure is directed to compounds of formula (I): where r, q, R1a, R1b, R1c, R1d, R1e, R2, R3, R4a, R5a, R5b, R6a, R6b, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceu...  
WO/2018/098799A1
The present invention relates to a process for preparing a polyurethane foam by reacting a polyisocyanate with a polyol in the presence of a blow agent and a particular family of amine. The present invention also relates to a polyurethan...  
WO/2018/090982A1
Provided are a benzodicycloalkane derivative, and a preparation method and use thereof. In particular, provided is a compound of formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method th...  
WO/2018/088797A1
The present invention relates to a spirobifluorene compound and a perovskite solar cell comprising the same and, more particularly, to a spirobifluorene compound which can be used as a hole transport material of a perovskite solar cell, ...  
WO/2018/087064A1
The invention relates to a method for producing triarylorganoborates from organoboronic acid esters in the presence of an n-valent cation 1/n Kn+, comprising the anhydrous treatment of the reaction mixture, and to the use of the obtained...  
WO/2018/084625A1
The present invention relates to a novel method for preparing (S)-N1-(2-aminoethyl)-3-(4-alkoxyphenyl)propane-1,2-diamine trihydrochloride.  
WO/2018/071437A1
The disclosure provides methods for treating vulvovaginal atrophy (WA) and osteoporosis in breast cancer survivors and survivors of other malignancies with an effective amount of lasofoxifene, a pharmaceutically acceptable salt thereof, ...  
WO/2018/062233A1
The present invention provides a compound represented by formula (I), which is usable as a cationic lipid facilitating the introduction of a nucleic acid into a cell, or the like, and a composition, or the like, containing the compound.  
WO/2018/064231A1
Methods of treating ovarian cancer are disclosed.  
WO/2018/051278A3
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051278A4
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051278A2
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/048932A1
Methods and compositions for use in treating, preventing or improving diseases related to the liver in an animal, including but not limited to nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) or nonalcoholic steato...  
WO/2018/048319A1
The invention relates to chemical engineering processes, and more particularly to liquid-phase catalytic methods for producing, in the presence of hydrogen, alkylated para-phenetidine for use as a chemical substance or as a gasoline addi...  
WO/2018/048320A1
The invention relates to chemical engineering processes, and more particularly to liquid-phase catalytic methods for producing, in the presence of hydrogen, alkylated para-anisidine for use as a chemical substance or as a gasoline additi...  
WO/2018/033200A1
The present invention relates to ionic compounds containing an anion, and a cation having the following structural formula (1): R1R2R3N+-(|inker1)-O-(iinker2)-(FC) wherein: - R1 and R2 either linear or branched alkyl groups or together f...  
WO/2018/021517A1
The present invention relates to a 4-alkoxy-3-(trifluoromethyl)benzyl alcohol production method with which it is possible to achieve a higher conversion rate and to closely control the generation of by-products by using DIBAL as a reduci...  
WO/2018/022841A1
Disclosed herein are scavenging and antifouling compositions useful in applications relating to the production, transportation, storage, and separation of crude oil and natural gas. Also disclosed herein are methods of using the composit...  
WO/2018/021526A1
A quaternary ammonium compound represented by formula (1). [(R1)m(R2)4-mN+]nXn- (1) (In the formula, each R1 independently represents an unsubstituted alkyl group or substituted alkyl group having 1-30 carbon atoms, an aryl group having ...  
WO/2018/020263A1
The present invention provides compounds of the formula (I) and their use as Kv3 modulators.  
WO/2018/018091A1
The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.  
WO/2018/009720A1
Methods and compounds for use in promoting survival of at least one eukaryotic cell, wherein the compounds are effective as gamma-ketoaldehyde scavengers.  
WO/2018/004945A1
A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):  
WO/2017/216507A1
The invention relates to difluorocyclopropane compounds, methods for their manufacture, and their uses for example as medicaments. According to one aspect, there is provided a compound of general formula (I): wherein X and Y are phenyl g...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/210371A3
Methods and small molecule compounds for inhibition of sodium channels are provided. One example of a class of compounds that may be used is represented by the compound of Formula (I) or a pharmaceutically acceptable salt, N-oxide or sol...  

Matches 1 - 50 out of 10,192