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Matches 1 - 50 out of 10,105

Document Document Title
WO/2018/071437A1
The disclosure provides methods for treating vulvovaginal atrophy (WA) and osteoporosis in breast cancer survivors and survivors of other malignancies with an effective amount of lasofoxifene, a pharmaceutically acceptable salt thereof, ...  
WO/2018/062233A1
The present invention provides a compound represented by formula (I), which is usable as a cationic lipid facilitating the introduction of a nucleic acid into a cell, or the like, and a composition, or the like, containing the compound.  
WO/2018/064231A1
Methods of treating ovarian cancer are disclosed.  
WO/2018/051278A2
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/048932A1
Methods and compositions for use in treating, preventing or improving diseases related to the liver in an animal, including but not limited to nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) or nonalcoholic steato...  
WO/2018/048319A1
The invention relates to chemical engineering processes, and more particularly to liquid-phase catalytic methods for producing, in the presence of hydrogen, alkylated para-phenetidine for use as a chemical substance or as a gasoline addi...  
WO/2018/048320A1
The invention relates to chemical engineering processes, and more particularly to liquid-phase catalytic methods for producing, in the presence of hydrogen, alkylated para-anisidine for use as a chemical substance or as a gasoline additi...  
WO/2018/033200A1
The present invention relates to ionic compounds containing an anion, and a cation having the following structural formula (1): R1R2R3N+-(|inker1)-O-(iinker2)-(FC) wherein: - R1 and R2 either linear or branched alkyl groups or together f...  
WO/2018/021517A1
The present invention relates to a 4-alkoxy-3-(trifluoromethyl)benzyl alcohol production method with which it is possible to achieve a higher conversion rate and to closely control the generation of by-products by using DIBAL as a reduci...  
WO/2018/022841A1
Disclosed herein are scavenging and antifouling compositions useful in applications relating to the production, transportation, storage, and separation of crude oil and natural gas. Also disclosed herein are methods of using the composit...  
WO/2018/021526A1
A quaternary ammonium compound represented by formula (1). [(R1)m(R2)4-mN+]nXn- (1) (In the formula, each R1 independently represents an unsubstituted alkyl group or substituted alkyl group having 1-30 carbon atoms, an aryl group having ...  
WO/2018/020263A1
The present invention provides compounds of the formula (I) and their use as Kv3 modulators.  
WO/2018/018091A1
The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.  
WO/2018/009720A1
Methods and compounds for use in promoting survival of at least one eukaryotic cell, wherein the compounds are effective as gamma-ketoaldehyde scavengers.  
WO/2018/004945A1
A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):  
WO/2017/216507A1
The invention relates to difluorocyclopropane compounds, methods for their manufacture, and their uses for example as medicaments. According to one aspect, there is provided a compound of general formula (I): wherein X and Y are phenyl g...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/210371A3
Methods and small molecule compounds for inhibition of sodium channels are provided. One example of a class of compounds that may be used is represented by the compound of Formula (I) or a pharmaceutically acceptable salt, N-oxide or sol...  
WO/2017/210371A2
Methods and small molecule compounds for inhibition of sodium channels are provided. One example of a class of compounds that may be used is represented by the compound of Formula (I) or a pharmaceutically acceptable salt, N-oxide or sol...  
WO/2017/182097A1
The present invention relates an improved and well reproducible process for the preparation of Enclomiphene citrate having needle shaped crystal habit, and moreover, it is also related to a solid form of Enclomiphene citrate.  
WO/2017/177326A1
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...  
WO/2017/162476A1
An etheramine mixture comprising of at least one amine selected from the group consisting of amine of Formula (I) and amine of Formula (II) wherein R1-R12 are independently selected from H, alkyl, cycloalkyi, aryl, alkylaryl, or arylalky...  
WO/2017/162477A1
An etheramine mixture comprising at least 90% by weight, based on the total weight of the etheramine mixture, of an amine of Formula (I) and/or (II), wherein R1-R12 are independently selected from H, alkyl, cycloalkyl, aryl, alkylaryl, o...  
WO/2017/153779A1
A lipid comprising a tri-chain cation of formula (la) having a cationic head group and three C12-24 hydrocarbyl groups for use in non-viral gene delivery systems, for example in the formation of lipopolyplex transfection vectors. Excepti...  
WO/2017/155686A1
An acyclic fluorinated compound of formula (I) is amine -containing acyclic hydrofluoroethers. The acyclic fluorinated compound is useful as heat transfer, solvent cleaning, fire extinguishing agents and electrolyte solvents and additives.  
WO/2017/151733A1
Disclosed herein are transfection complexes comprising at least one cell surface ligand; at least one helper lipid component; and a transfection enhancer. Also disclosed are pharmaceutical compositions comprising the disclosed transfecti...  
WO/2017/147145A1
The disclosure provides for coating compositions comprising macrocycles and salts in aqueous buffer and the use of the coating composition to prevent absorption of small molecules into polymeric surfaces.  
WO/2017/141806A1
The present invention addresses the problem of providing: a novel ionic compound which can be preferably added to a non-aqueous electrolytic solution for an electrical storage device; a novel non-aqueous electrolytic solution containing ...  
WO/2017/138566A1
The present invention provides a triphenylamine derivative represented by general formula (1). (In the formula, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14 and R15 independently represent a hydrogen atom, a substituted or...  
WO/2017/138017A1
The present, invention relates to a cost effective, environment friendly industrially viable process for the preparation of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepine-2-one, an intermediate used in the preparation of ivabradine, without ...  
WO/2017/137047A1
The invention relates to a method for arylation of amines, such as aliphatic amines by reaction of aryl-halogens, e.g. chloro- or fluorobenzene derivatives without strongly electron withdrawing substituents in the presence of a strong base.  
WO/2017/137955A1
The present invention relates to novel chiral 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine (5) and racemic 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine () and its use in improved and ...  
WO/2017/134841A1
The present invention provides: a liquid crystal display element that is highly reliable, has improved various characteristics as a liquid crystal display element, and in which dropping marks do not readily occur during production, witho...  
WO/2017/132912A1
The present invention provides an alkylamine with a benzoalicyclic substituent and an application thereof. More specifically, the invention relates to a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, a...  
WO/2017/123333A1
The present disclosure provides a process for the co-preparation of a polyetheramine and an alkylene amine mixture by aminating a liquid polyol initiator mixture comprising an alkoxylated alcohol and a solid high melting polyol. The poly...  
WO/2017/113439A1
Provided are a plating additive for electrodeposition, and the corresponding fabrication method thereof. The plating additive enables to electroplate holes on a substrate with good height uniformity within a feature and among features at...  
WO/2017/100856A1
The present invention relates to a novel dendrimer. The present invention also relates to formulations comprising the dendrimer with improved characteristics. For instance, the present invention relates to formulations comprising pestici...  
WO/2017/080770A1
The invention relates to the synthesis of tamoxifen, endoxifen and derivatives thereof. Starting from a substituted benzoic acid derivative and 2-phenoxyethyl halide, the intermediate product of general formula (I) is obtained. The compo...  
WO/2017/079965A1
The present invention relates to a catalyst for aminating a polyether polyol and preparation method thereof and a method of preparing a polyetheramine using the catalyst. The catalyst has active components and a carrier. The active compo...  
WO/2017/076293A1
The invention relates to a method for preparing an oxazolidinone intermediate. Specifically, a synthesis procedure for the intermediate comprises: directly performing a "one-pot" reaction on a compound I, a compound J or a compound L wit...  
WO/2017/067497A3
Disclosed are a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof. In the present invention, the amphiphilic hypocrellin derivative having substituted functional groups s...  
WO/2017/070651A1
Disclosed is a process for preparing (Z)-endoxifen, comprising (i) recrystallizing an input crystalline solid comprising a mixture of (Z)-endoxifen (1) and (E)-endoxifen (2) from a first solvent to provide a first crystalline solid and a...  
WO/2017/068496A1
The present application relates to an improved process for the preparation of Eliglustat or its pharmaceutically acceptable salts thereof. Further relates to isolation of intermediates in the form of solid and their use for preparation o...  
WO/2017/067497A9
Disclosed are a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof. In the present invention, the amphiphilic hypocrellin derivative having substituted functional groups s...  
WO/2017/064490A1
There is provided a compound of the formula wherein: A represents a phenyl group, a naphthyl group, a biphenyl group or two phenyl groups linked by a C1-C8 alkyl chain; B1 and B2 in each occurrence are independently selected side chains ...  
WO/2017/055067A1
The invention relates to a compound of general formula (I) where R1 through R8, x, y, and z are defined as in the description. The invention also relates to an absorbent comprising a solution of the compound, and the use thereof, and a m...  
WO/2017/042514A1
The present invention relates to a compound of formula (I): in which: - the R1 and R2 groups, which may be identical or different, are, independently of one another, a saturated or unsaturated, linear, branched or cyclic hydrocarbon grou...  
WO/2017/042099A1
The present invention relates to compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof wherein ASC is -N(R8)ASC-1; ASC-1 is C 2-C 5alkylene-N(R9a)R9b or C(=O)-C 1-C 4alkylene-N(R9a)R9b, wherein in alkylen...  
WO/2017/036436A1
The present invention provides primin derivatives of general formula II and/or III, wherein R1 is selected from the group consisting of methyl and hydrogen, R2 is selected from the group consisting of methoxy, hydroxy, hydrogen, R3 is se...  
WO/2017/035879A1
The present invention provides a method for preparing single-layer metal phosphate and applications thereof. The method comprises: (1) carrying out intercalation treatment on layered metal phosphate by means of alkylol amine, so as to ob...  

Matches 1 - 50 out of 10,105