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Matches 1 - 50 out of 10,059

Document Document Title
WO/2018/009720A1
Methods and compounds for use in promoting survival of at least one eukaryotic cell, wherein the compounds are effective as gamma-ketoaldehyde scavengers.  
WO/2018/004945A1
A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):  
WO/2017/216507A1
The invention relates to difluorocyclopropane compounds, methods for their manufacture, and their uses for example as medicaments. According to one aspect, there is provided a compound of general formula (I): wherein X and Y are phenyl g...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/210371A2
Methods and small molecule compounds for inhibition of sodium channels are provided. One example of a class of compounds that may be used is represented by the compound of Formula (I) or a pharmaceutically acceptable salt, N-oxide or sol...  
WO/2017/182097A1
The present invention relates an improved and well reproducible process for the preparation of Enclomiphene citrate having needle shaped crystal habit, and moreover, it is also related to a solid form of Enclomiphene citrate.  
WO/2017/177326A1
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...  
WO/2017/162476A1
An etheramine mixture comprising of at least one amine selected from the group consisting of amine of Formula (I) and amine of Formula (II) wherein R1-R12 are independently selected from H, alkyl, cycloalkyi, aryl, alkylaryl, or arylalky...  
WO/2017/162477A1
An etheramine mixture comprising at least 90% by weight, based on the total weight of the etheramine mixture, of an amine of Formula (I) and/or (II), wherein R1-R12 are independently selected from H, alkyl, cycloalkyl, aryl, alkylaryl, o...  
WO/2017/153779A1
A lipid comprising a tri-chain cation of formula (la) having a cationic head group and three C12-24 hydrocarbyl groups for use in non-viral gene delivery systems, for example in the formation of lipopolyplex transfection vectors. Excepti...  
WO/2017/155686A1
An acyclic fluorinated compound of formula (I) is amine -containing acyclic hydrofluoroethers. The acyclic fluorinated compound is useful as heat transfer, solvent cleaning, fire extinguishing agents and electrolyte solvents and additives.  
WO/2017/151733A1
Disclosed herein are transfection complexes comprising at least one cell surface ligand; at least one helper lipid component; and a transfection enhancer. Also disclosed are pharmaceutical compositions comprising the disclosed transfecti...  
WO/2017/147145A1
The disclosure provides for coating compositions comprising macrocycles and salts in aqueous buffer and the use of the coating composition to prevent absorption of small molecules into polymeric surfaces.  
WO/2017/141806A1
The present invention addresses the problem of providing: a novel ionic compound which can be preferably added to a non-aqueous electrolytic solution for an electrical storage device; a novel non-aqueous electrolytic solution containing ...  
WO/2017/138566A1
The present invention provides a triphenylamine derivative represented by general formula (1). (In the formula, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14 and R15 independently represent a hydrogen atom, a substituted or...  
WO/2017/138017A1
The present, invention relates to a cost effective, environment friendly industrially viable process for the preparation of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepine-2-one, an intermediate used in the preparation of ivabradine, without ...  
WO/2017/137047A1
The invention relates to a method for arylation of amines, such as aliphatic amines by reaction of aryl-halogens, e.g. chloro- or fluorobenzene derivatives without strongly electron withdrawing substituents in the presence of a strong base.  
WO/2017/137955A1
The present invention relates to novel chiral 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine (5) and racemic 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine () and its use in improved and ...  
WO/2017/134841A1
The present invention provides: a liquid crystal display element that is highly reliable, has improved various characteristics as a liquid crystal display element, and in which dropping marks do not readily occur during production, witho...  
WO/2017/132912A1
The present invention provides an alkylamine with a benzoalicyclic substituent and an application thereof. More specifically, the invention relates to a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, a...  
WO/2017/123333A1
The present disclosure provides a process for the co-preparation of a polyetheramine and an alkylene amine mixture by aminating a liquid polyol initiator mixture comprising an alkoxylated alcohol and a solid high melting polyol. The poly...  
WO/2017/113439A1
Provided are a plating additive for electrodeposition, and the corresponding fabrication method thereof. The plating additive enables to electroplate holes on a substrate with good height uniformity within a feature and among features at...  
WO/2017/100856A1
The present invention relates to a novel dendrimer. The present invention also relates to formulations comprising the dendrimer with improved characteristics. For instance, the present invention relates to formulations comprising pestici...  
WO/2017/080770A1
The invention relates to the synthesis of tamoxifen, endoxifen and derivatives thereof. Starting from a substituted benzoic acid derivative and 2-phenoxyethyl halide, the intermediate product of general formula (I) is obtained. The compo...  
WO/2017/079965A1
The present invention relates to a catalyst for aminating a polyether polyol and preparation method thereof and a method of preparing a polyetheramine using the catalyst. The catalyst has active components and a carrier. The active compo...  
WO/2017/076293A1
The invention relates to a method for preparing an oxazolidinone intermediate. Specifically, a synthesis procedure for the intermediate comprises: directly performing a "one-pot" reaction on a compound I, a compound J or a compound L wit...  
WO/2017/067497A3
Disclosed are a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof. In the present invention, the amphiphilic hypocrellin derivative having substituted functional groups s...  
WO/2017/070651A1
Disclosed is a process for preparing (Z)-endoxifen, comprising (i) recrystallizing an input crystalline solid comprising a mixture of (Z)-endoxifen (1) and (E)-endoxifen (2) from a first solvent to provide a first crystalline solid and a...  
WO/2017/068496A1
The present application relates to an improved process for the preparation of Eliglustat or its pharmaceutically acceptable salts thereof. Further relates to isolation of intermediates in the form of solid and their use for preparation o...  
WO/2017/064490A1
There is provided a compound of the formula wherein: A represents a phenyl group, a naphthyl group, a biphenyl group or two phenyl groups linked by a C1-C8 alkyl chain; B1 and B2 in each occurrence are independently selected side chains ...  
WO/2017/055067A1
The invention relates to a compound of general formula (I) where R1 through R8, x, y, and z are defined as in the description. The invention also relates to an absorbent comprising a solution of the compound, and the use thereof, and a m...  
WO/2017/042514A1
The present invention relates to a compound of formula (I): in which: - the R1 and R2 groups, which may be identical or different, are, independently of one another, a saturated or unsaturated, linear, branched or cyclic hydrocarbon grou...  
WO/2017/042099A1
The present invention relates to compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof wherein ASC is -N(R8)ASC-1; ASC-1 is C 2-C 5alkylene-N(R9a)R9b or C(=O)-C 1-C 4alkylene-N(R9a)R9b, wherein in alkylen...  
WO/2017/036436A1
The present invention provides primin derivatives of general formula II and/or III, wherein R1 is selected from the group consisting of methyl and hydrogen, R2 is selected from the group consisting of methoxy, hydroxy, hydrogen, R3 is se...  
WO/2017/035879A1
The present invention provides a method for preparing single-layer metal phosphate and applications thereof. The method comprises: (1) carrying out intercalation treatment on layered metal phosphate by means of alkylol amine, so as to ob...  
WO/2017/024703A1
The present invention provides an aromatic amine compound comprising a structure of formula (I). The compound provided according to the invention has luminous efficacy, which will result in, when in a condition of a current density of 20...  
WO/2017/025448A1
The invention relates to the use of an amine of formula (I) in a curing agent for epoxy resins, to a curing agent for epoxy resins containing the amine of formula (I) and to resultant epoxy resin compositions which can be used particular...  
WO/2017/016960A1
The present invention relates to a process for synthesizing a compound of formula (I), wherein R1 is C1-6alkoxy or haloC1-6alkoxy, R2 is C1-6alkyl unsubstituted or substituted by a substituent selected from C1-6alkoxy and haloC1-6alkoxy,...  
WO/2017/005710A1
The present invention relates phenoxyhalogenphenylamidmes of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to an agroch...  
WO/2017/002742A1
Provided is a photoelectric conversion element having excellent durability against photoirradiation. This photoelectric conversion element has a negative electrode, a positive electrode, an active layer that is provided between the negat...  
WO/2016/202742A1
The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and ...  
WO/2016/202808A2
The present invention relates to a process for the synthesis of tapentadol intermediates comprising the following route of synthesis: (I) → (II) → (III) → (IV) → (V).  
WO/2016/202808A3
The present invention relates to a process for the synthesis of tapentadol intermediates comprising the following route of synthesis: (I) → (II) → (III) → (IV) → (V).  
WO/2016/202688A1
The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and ...  
WO/2016/200827A1
A compound, or a pharmaceutically acceptable salt thereof, having a formula I of: (I) wherein Ar is an arylene or heteroarylene; R1 has a structure of: (II) wherein W is an alkanediyl, alkenediyl, a carbonyl, or a combination thereof; X ...  
WO/2016/193220A1
The present invention relates to a method for changing the pigmentation of a skin, a mucous membrane or hair with a compound of general formula (I), a cosmetic use of said compound of general formula (I), to cosmetic compositions compris...  
WO/2016/181292A1
The present invention relates to a process for the preparation of 5-(3,4-dimethoxyphenylethyl) methyl-amino-2-(3,4-dimethoxyphenyl)-2-isopropyl valeronitrile, which is known as Verapamil. The present invention also relates to a process f...  
WO/2016/177307A1
Among others, the present invention provides isocyanate resin compositions which include an isocyanate compound containing two or more isocyanate functional groups; a chain extender comprising a degradable diamine and optionally a dihydr...  
WO/2016/169477A1
Disclosed are a Y-type polyethylene glycol derivative and a preparation method therefor. The present invention has the advantages of determined molecular weights and the number of chains and can avoid the defects of nonuniformity of a PE...  
WO/2016/166921A1
[Problem] The purpose of the present invention is to provide an asymmetrical diamine suited to the production of polyimide, and a method for producing the asymmetrical diamine. [Solution] The present invention provides a compound represe...  

Matches 1 - 50 out of 10,059