| Document |
Document Title |
|
WO/2008/010455A1 |
Disclosed is a method for producing a β-diaryl electron-withdrawing group substituted compound at high yield with high selectivity. Specifically, an optically active β-diaryl electron-withdrawing group substituted compound represented ...
|
|
WO/2007/135179A1 |
Ligands of the formula (I) secondary phosphine-Q-P(=O)HR1 (I) in the form of mixtures of diastereomers or pure diastereomers, in which secondary phosphine is a secondary phosphine group with hydrocarbon radicals or heterohydrocarbon radi...
|
|
WO/2007/105668A1 |
The invention provides a novel immobilized Lewis acid catalyst which exhibits high catalytic activity in an aqueous solution and which permits recovery and reuse or long-term continuous use. The invention relates to an immobilized Lewis ...
|
|
WO2006138510B1 |
The present invention is related substituted enaminones represented by a compound of Formula I that are novel allosteric modulators of a7 nAChRs. The invention also discloses the treatment of disorders that are responsive to enhancement ...
|
|
WO/2007/022979A2 |
The invention relates to mediator systems containing dihydroxylated and/or polyhydroxylated quinoid compounds from the group of anthraquinones, naphthoquinones or anthracene-9,10-diolates of ammonium metals, alkali metals, alkaline-earth...
|
|
WO/2007/019752A1 |
The present invention provided a process for the preparation of gabapentin hydrochloride. The process comprises: conventing 1,5-dicyano-2,4-dioxo-3-azaspiro[5,5]undecane into 1,5-dicarbamoyl-2,4-dioxo-3-azaspiro[5,5]undecane at a tempera...
|
|
WO/2007/011005A1 |
A process for producing a biaryl compound, comprising reacting an aromatic organic compound with at least one compound selected from the group consisting of an aromatic organoboron compound and a boroxin ring compound in the presence of ...
|
|
WO/2007/007791A1 |
A process for the decomposition and recovery of isocyanate compounds which comprises introducing continuously an isocyanate compound having at least one isocyanate group or at least one group derived from an isocyanate group in a molten ...
|
|
WO/2007/000918A1 |
Benzylamine derivatives having structures represented by the general formula (1): (1) a method for the optical resolution of benzylamine derivatives which comprises using optically active mandelic acid as the reagent for optical resoluti...
|
|
WO/2006/134457A2 |
Synthesis of 2,5-bis-diamine-[l,4]benzoquinonic derivatives having the general formula (I), products and intermediates of said synthesis; the synthesis involves the use of p-benzoquinones having the general formula (IX) and diamines havi...
|
|
WO/2006/125397A1 |
Nonsteroic androgen acceptor regulator compounds of the general formula (I), pharmaceutically acceptable salts thereof, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of ...
|
|
WO2005080314B1 |
A process for the preparation of compound AQ4N of formula (2) or a salt or solvate thereof wherein the said process includes the reaction step: Formula (1), Formula (2), where compound AQ4 of formula (1) is oxidised to compound AQ4N of f...
|
|
WO/2006/091301A2 |
Protecting the security of an entity by using passcodes is disclosed. A passcode device 101 generates a passcode Pi. In an embodiment, the passcode Pi is generated in response to receipt of user information. The passcode Pi 1 is received...
|
|
WO/2006/090256A1 |
This present invention relates to processes for the preparation of 3-N-methyl-N-phenylaminoacroline.
|
|
WO/2006/087166A1 |
Provided is a process for the preparation of N-monosubstituted β-aminoalcohol sulfonates of formula (Ia), (Ib) wherein R1 is C6-20 aryl or C4-12 heteroaryl, each optionally being substituted with one or more halogen atoms and/or one or ...
|
|
WO/2006/079090A2 |
Methods and inte&pgr nediates for the preparation of Fenoldopam mesylate and ntermediates thereof are provided.
|
|
WO/2006/072785A2 |
The present invention relates to novel base stable ionic liquids and uses thereof as solvents in chemical reactions, especially base catalysed chemical reactions and reactions comprising the use of strong basis.
|
|
WO/2006/069798A1 |
The invention relates to a process for the preparation of a chiral amine, whereby a ketone or aldehyde is contacted with an enantiomerically enriched phenylglycine amide to give an imine, whereby the imine is subsequently contacted with ...
|
|
WO/2005/118524A1 |
A preparation method of [(S)-(-)-alpha-methylamino phenylacetone ]2 (2R,3R)-tartaric acid derivates is disclosed, which comprises forming salt from (±) -alphamethylamino phenylacetone, (R)-(+)-alpha-methylamino phenylacetone or (±)...
|
|
WO/2005/100300A1 |
A 5-aminolevulinic acid salt which is useful in the fields of microorganisms, fermentation, animals, medical science, plants and so on; a process for producing the same; a medicinal composition containing the same; and a plant vitalizer ...
|
|
WO/2005/084803A1 |
[PROBLEMS] To provide an asymmetric reaction catalyst which is excellent in yield and stereoselectivity and easy of handling and a process for the production of optically active compounds with the same. [MEANS FOR SOLVING PROBLEMS] An as...
|
|
WO/2005/070875A1 |
A process for the production of amines which is characterized by reacting an imine with a nucleophilic compound (except trialkylsilyl vinyl ethers) in the presence of a phosphoric acid derivative represented by the general formula (1): (...
|
|
WO/2005/070869A1 |
The present invention describes an improved catalyst and process for the selective hydrogenation of nitro aromatics, nitrosoaromatics and aromatic hydroxyl amines to their corresponding amines using gaseous hydrogen, in the presence of s...
|
|
WO/2005/042481A2 |
Ketoamine compounds and related methods for reactivation of tumor suppressor protein p53.
|
|
WO/2004/089873A1 |
Process for crystallising Bupropion hydrochloride comprising the following stages: a) Bupropion hydrochloride is dissolved in a mixture comprising methanol and a precipitating solvent for Bupropion hydrochloride; b) any insoluble residue...
|
|
WO/2004/024674A1 |
This invention is related to the preparation of bupropion hydrochloride. The reaction of 3'-chloropropiophenone with bromine in presence of tert-butylamine to prepare the bupropion free base and then recovering of bupropion hydrochloride...
|
|
WO/2004/020391A1 |
The invention relates to monoalkylamino ketones of formula (I), wherein R1 and R2 have the meanings as cited in the description.
|
|
WO/2004/005239A1 |
The invention relates to a process for the synthesis of N-monosubstituted β-amino alcohols of formula (I) and/or an addition salt of a proton acid, wherein R1 and R2 independently represent alkyl, cycloalkyl, aryl or aralkyl, each being...
|
|
WO/2003/106399A2 |
The invention provides processes for preparing N-protected β-amino aldehyde compounds which are useful as synthetic intermediates for preparing glycopeptide antibiotic derivatives. The processes include cleaving a carbon-carbon double b...
|
|
WO/2003/104186A1 |
A process for easily producing, from an easily available inexpensive starting material, an optically active ß-amino alcohol useful as an intermediate for medicines. An easily available &agr -substituted ketone is reacted with an optical...
|
|
WO/2003/101933A1 |
Novel solid supported intermediate products of the general formula I coupled to a solid polymeric support through one or both of the R&supl groups or through the R4 group which are suitable for synthesis of heterocyclic compounds are dis...
|
|
WO/2003/091200A1 |
A process for the preparation of 2-aminoketones represented by the general formula (3): (3) [wherein R is halogeno, cyano, C1-12 alkyl, or the like; R2 is hydrogen or C1-6 alkyl; n is an integer of 0 to 5; and R1 is hydrogen or C1-12 alk...
|
|
WO/2003/087033A1 |
Process for the preparation of enantiomerically enriched amino aldehydes and amino alcohols, wherein a corresponding enantiomerically enriched amino nitrile is subjected to hydrogenation in the presence of hydrogen, a hydrogenation catal...
|
|
WO/2003/087035A1 |
2,5-bis-diamine-[1,4]benzoquinonic derivatives, having a general formula (I) have proved useful for the treatment of Alzheimer's disease; a method for preparing them and intermediates used in said method are also described. Fomula (I).
|
|
WO/2003/037846A1 |
An improved method of producing keto acids having the formula (I), wherein R¿1? and R¿2? independently represent (a) hydrogen, wherein at least one of R¿1? and R¿2? do not stand for hydrogen, (b) branched or unbranched alkyl of 1-18 ...
|
|
WO/2003/006420A1 |
The present invention is directed to a method of converting an aryl compound to an aniline compound, comprising the steps of (1)providing an aryl compound containing a halide group or a sulfur-containing group; (2) reacting the aryl comp...
|
|
WO2001047866A9 |
The invention relates to substituted 1 and 2 naphthol Mannich bases, a method for the production thereof, medicaments containing said compounds and the use of said compounds in the production of medicaments.
|
|
WO/2002/085838A1 |
The present invention relaters to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the ...
|
|
WO2001098265B1 |
The present invention describes a new process for obtainment of the cetamine enantiomers, form the racemic cetamine resolution with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers...
|
|
WO/2002/076926A1 |
There are disclosed compounds of formula (I) wherein the variables A and B are an aryl or heteroaryl group as defined in the claims, or a prodrug thereof, or a pharmaceutically acceptable salt, solvate or isomer of said compound or of sa...
|
|
WO/2002/066416A1 |
To more efficiently provide CPT, which is a starting compound for irinotecan hydrochloride and various camptothecin derivatives, by a practically usable total synthesis, a means whereby 2'-amino-5'-hydroxypropiophenone corresponding to t...
|
|
WO/2002/057199A1 |
The invention relates to a process for carrying out a homogeneously catalyzed C-C coupling reaction between an optionally substituted (hetero)aromatic bromide compound and a second reactant, which is chosen from the group of olefins in w...
|
|
WO/2002/053537A1 |
The present invention relates to a process for preparing (±)-trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidi
ne of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX') methods for ...
|
|
WO/2002/042254A1 |
The present invention relates to a process of producing carbonyl a-substituted nitrogen-containing compounds, which comprises reacting a-halo-ketone or a-halo-aldehyde with primary amine, secondary amine or heterocycle compound containin...
|
|
WO/2002/034712A1 |
A process for preparing substituted aromatic compounds of the general formula (||) or salts thereof: (||) [wherein A is an optionally substituted aromatic homo- or hetero-cycle; X is O- or the like; Y is NR?1¿- or the like; and B is an ...
|
|
WO/2002/018319A1 |
The present invention relates to a process for the preparation of N-arylanthranilic acids, and a process for the preparation of N-aryl anthranilic esters, amides, and hydroxamic esters.
|
|
WO/2002/014256A1 |
The present invention relates to a process for the preparation of $g(a)' chloroketones, such as 4-phenyl-3-t-butyloxy-carbonylamino)-2-keto-1-chlorobutane by reacting certain aryl amino acid esters, e.g. N-(2-t-butoxycarbonyl)-L-phenylal...
|
|
WO/2002/011883A1 |
The present invention is directed to a transition metal catalyst, comprising a Group 8 metal and a ligand having the structure (I), wherein R', R' and R'' are organic groups having 1-15 carbon atoms, n = 1-5, and m = 0-4. The present inv...
|
|
WO/2002/010122A1 |
A method for preparing fatty hydroxamic acids and salts thereof comprising reacting a fatty acid derivative with an aqueous solution of a hydroxylamine.
|
|
WO/2002/008170A1 |
A process for producing optically active $g(a)-hydroxy-$g(b)-aminocarboxylic acid derivatives. $g(a)-Aminoketone derivatives (4) are successively halogenated, reduced and hydrolyzed to thereby efficiently produce $g(a)-amino-$g(a)', $g(a...
|
