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Matches 1 - 50 out of 900

Document Document Title
WO/2018/013682A1
Covalent organic frameworks (COFs) usually crystallize as insoluble powders and their processing for suitable devices has been thought to be limited. Here, it is demonstrated that COFs can be mechanically pressed into shaped objects havi...  
WO/2017/211129A1
A method for manufacturing an ephedrine or pseudoephedrine intermediate, comprising: using 2-chloropropionyl chloride and benzene as starting raw materials and performing a Friedel-Crafts reaction using a Lewis acid catalyst to generate ...  
WO/2017/198812A3
Process for the manufacture of 2-substituted-5-(1-methylthio)alkylpyridines and a process for the manufacture of agriculturally or pharmaceutically active substances comprising the process for the manufacture of 2-substituted-5-(1- methy...  
WO/2017/137955A1
The present invention relates to novel chiral 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine (5) and racemic 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine () and its use in improved and ...  
WO/2017/077550A1
The present invention discloses a novel metal free process for the regioselective synthesis of α-substituted carbonyl compounds of formula I from alkene, X is selected from the following compounds (A, B).  
WO/2017/067497A3
Disclosed are a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof. In the present invention, the amphiphilic hypocrellin derivative having substituted functional groups s...  
WO/2017/057460A1
Provided is a method for producing an organic compound, wherein the organic compound is an industrially useful compound, and a deodorization step, for removing from a reaction solution odorants that are generated in or remaining after a ...  
WO/2017/054112A1
The present invention relates to a method of preparing a 3-fluoroalkyl-1-methylpyrazole-4-carboxylic acid comprising the following steps: Step 1, performing a condensation reaction on the fluoroacetyl halide derivative shown in formula I...  
WO/2017/035224A1
Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are ...  
WO/2016/207252A1
A method of preparing a compound represented by general formula (3) : Formula (3). R1 and R2 are each independently an alkyl group. The method includes reacting a compound represented by general formula (2) : Formula (2) with an alkylami...  
WO/2016/202254A1
Provided are a preparation method for synthesizing a pyrazolecarboxylic acid derivative of the following formula (I), which is suitable for industrial production, and an intermediate as shown by the following formula (II). The method is ...  
WO/2016/150208A1
Disclosed are a pharmaceutical composition and dosage form containing a glaucocalyxin A derivative as represented by the formula (I) or salt thereof, and a preparation method and use of said composition and dosage form; the anti-autoimmu...  
WO/2016/150206A1
Disclosed is a glaucocalyxin A derivative -- dimethylamino glaucocalyxin A hydrochloride salt -- and two crystalline forms thereof. The dimethylamino glaucocalyxin A hydrochloride salt provided by the present invention has good water sol...  
WO/2016/150207A1
Provided is a glaucocalyxin A derivative, or salt thereof, as represented by the formula (I), a method for preparation of said glaucocalyxin A derivative, and a use for said glaucocalyxin A derivative in preparing pharmaceuticals for fig...  
WO/2016/152886A1
The present invention provides a novel method for producing pyrazole derivatives useful as intermediates of pharmaceuticals and agricultural chemicals, as well as novel intermediate compounds in this method. The present invention pertain...  
WO/2016/071249A1
The present invention relates to a novel method for producing substituted biphenylamines.  
WO/2016/057770A1
The present disclosure describes a method of coupling a first compound to a second compound, the method comprising: providing the first compound having a fluorosulfonate substituent; providing the second compound comprising an amine; and...  
WO/2016/035609A1
The present invention provides a method for producing a benzaldehyde in which an amino group is bonded in the 2 position, a halogeno group or an alkoxy group is bonded in the 3 position, and a hydrogen atom, an alkyl group, a halogeno gr...  
WO/2015/198608A1
[Problem] To provide: a method for manufacturing a reaction product in which there is employed a phase interface reaction that makes it possible to efficiently bring about a reaction between a plasma-form substance (ozone, nitrogen plasm...  
WO/2015/170124A1
Graphene is chemically modified by a process resulting in the introduction of functional groups located only at an edge of the graphene plane. The functionalised graphene finds uses in numerous applications and further chemical synthesis...  
WO/2015/109963A1
Disclosed are an o-phenyl chalcone compound and preparation method and use thereof The o-phenyl chalcone compound is capable of inhibiting the aggregation assembly of microtubules in tumour cells and influencing the mitosis of the cells,...  
WO/2014/207761A1
The present invention relates to transition-metal-free process for the synthesis of tertiary arylamines comprises coupling reaction between arynes and N,N-dimethyl aniline compounds in presence of 18-crown-6, KF and THF.  
WO/2014/118038A1
The invention relates to novel phosphorus ligands and to a chemoselective and regioselective method for the hydroaminomethylation of olefins with at least one primary or secondary amine, with the addition of H2 and CO under catalytic con...  
WO/2014/082581A1
Disclosed is an α-(3, 5-dimethoxy benzylidene)-α'-hydrocarbyl methylene cyclic ketone, having a structure as represented by (I) or (II), wherein R is an aryl or alkyl; a preparation method is: mixing cyclic ketone and morpholine, and a...  
WO/2014/037444A1
Disclosed is a novel process for the reduction of nitro groups to amino derivatives, based on the use of trichlorosilane and an organic base, which is efficient from the chemical standpoint and of wide general applicability.  
WO/2014/005546A1
The present invention relates to a preparation method of tapentadol hydrochloride and compounds for preparation of the tapentadol hydrochloride. The preparation method comprises steps using a compound in a formula V or a hydrochloride th...  
WO/2013/121997A1
The purpose of the present invention is to provide: a method for obtaining hydrogen or deuterium with high efficiency or hydrogenating or deuterating an organic compound; a device for use in the method; and others. Provided are: a method...  
WO/2013/095301A1
Present invention relates to a method of preparing a chiral α- or β-substituted ketone from the corresponding β- or γ-substituted aldehyde, wherein the ketone has formula (I), (III) or (V), and the corresponding aldehyde has formula ...  
WO/2013/077720A1
Methods for producing methadone and its resolution to produce (R)-6-dimethylamino-4,4-diphenylheptan-3-one ((R)- methadone). Such methods producing first the precursor compound 4-(dimethylamino)-2,2-diphenylpentanitrile. Oxidation of 4-(...  
WO/2013/054181A1
Disclosed herein is a continuous tubular reactor based conversion of acetophenones to amino substituted acetophenones wherein the nitration is carried out at -10 to 10 °C followed by reduction to m-nitrophenone resulting in uniform outp...  
WO/2013/035084A3
The present invention relates to an improved process for the preparation of Fesoterodine and pharmaceutically acceptable salts thereof. The present invention particularly relates to a process for the preparation of Fesoterodine from O-be...  
WO/2013/008247A1
The invention discloses a process for preparation of (dl)-norepinephrine salt by reacting 3,4-dihydroxy-a-haloacetophenone with hexamethylenetetramine to provide hexamine salt; followed by hydrolysis and hydrogenation. The invention also...  
WO/2012/157982A3
The present invention relates to an amine compound, a method for preparing same, and a liquid crystal alignment agent, a liquid crystal alignment film, and a liquid crystal display device, having same. A liquid crystal alignment agent ha...  
WO/2012/136121A1
An amino phenylpropanoid compound, or a geometric isomer thereof, or a pharmaceutically acceptable salt or hydrate thereof as represented by Formula I, a preparation method therefor, and a pharmaceutical composition containing the compou...  
WO/2012/137741A1
A method for purifying an organic material, which can sublimate and purify an organic material having a high sublimation temperature and high heat resistance within a short time with high purity and high yield. The method comprises: redu...  
WO/2012/113860A3
The invention relates to a compound of formula (1): where R1 through R8, which can be identical or different from each other, each are selected from of the group comprising hydrogen and the radical -(CH2)k-X, where k is a whole number fr...  
WO/2012/081031A1
A substantially pure crystalline form A of tetrabenazine compound of structural formula I and processes for the preparation thereof is provided.  
WO/2012/076165A1
The present invention relates to a method for synthesising substituted aminocyclohexanone derivatives, comprising the following step (b) reaction of a compound of general formula (II) with an organolithium compound to form a compound of ...  
WO/2012/062041A1
Disclosed are aromatic ketone compounds with para- or meso-substituted multifunctional groups as represented by the general formulae I-III, preparation methods thereof, and free-radical polymerization photoinitiators comprising the compo...  
WO/2010/139482A1
A compound of formula (I) R-L-CO-X (I) (wherein R is a C10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or groups of heteroatoms selected from S, O, N, SO, SO2, said hydrocarbon group comprising at l...  
WO/2010/094674A3
A process for preparing N-[(1lR)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)- phenyl]propan-1-amine hydrochloride salt of formula (I) i.e. Cinacalcet hydrochloride and its intermediates of formulae (VII) and (VIII) wherein Z is chloride ...  
WO/2010/004386A2
The present invention provides an amorphous bupropion hydrobromide and an amorphous bupropion hydrobromide granulates with at least one pharmaceutically acceptable carrier, and a process for its preparation.  
WO/2010/004386A3
The present invention provides an amorphous bupropion hydrobromide and an amorphous bupropion hydrobromide granulates with at least one pharmaceutically acceptable carrier, and a process for its preparation.  
WO/2010/000856A1
The present invention relates to a method for producing substituted aminobiphenylene, in particular 2-aminobiphenylene, and a method for producing (het)acrylic acid amides of such aminobiphenyenes, in particular 2-aminobiphenyene.  
WO/2009/143714A1
Disclosed is a new 2,4-dihydroxyl chalcone derivative having the structure of general formula i and a pharmaceutically acceptable salt thereof, in which each group has the same meaning as defined in the specification, and a process for p...  
WO/2009/100996A2
The present invention provides innovative strategies for synthesizing pyrazole ring- functionalized benzodiazepinones. Alternative intermediates and high conversion strategies for forming alpha-aminobenzophenone intermediates involve a c...  
WO/2009/100996A3
The present invention provides innovative strategies for synthesizing pyrazole ring- functionalized benzodiazepinones. Alternative intermediates and high conversion strategies for forming alpha-aminobenzophenone intermediates involve a c...  
WO/2008/117054A2
The present invention provides P-chiral compounds of general formulae (II) and (III): in formula (II) at least one of R21, R25, R26and R30 is independently selected from CM alkyl, CF3, C1 -4 alkoxy, phenyl and benzyloxy and the remaining...  
WO/2008/117054A3
The present invention provides P-chiral compounds of general formulae (II) and (III): in formula (II) at least one of R21, R25, R26and R30 is independently selected from CM alkyl, CF3, C1 -4 alkoxy, phenyl and benzyloxy and the remaining...  
WO/2008/111515A1
Disclosed is a simple and highly efficient process for producing an aromatic carbonyl compound, which can produce an aromatic carbonyl compound having a substituent introduced to an aromatic ring adjacent to a carbonyl group. The process...  

Matches 1 - 50 out of 900