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Matches 301 - 350 out of 3,207

Document Document Title
WO2003097575A3
The invention provides novel amino-functionalised chalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infecti...  
WO/2004/014550A2
The invention relates to novel monocarbene complexes of nickel, palladium or platinum containing electron-deficient olefin ligands, to their production and to the use thereof in the homogeneous catalysis of organic reactions (Formula II ...  
WO/2004/013077A2
A compound of formula (I) or (II): wherein A is hydrogen or CR1R2; Y and Z are each, independently, hydrogen or a halogen; X is -NR4R5, or R7; R1 is hydrogen, or a substituted or unsubstituted alkyl or alkenyl group containing 1-4 carbon...  
WO/2004/011410A1
Compounds of formula (I):wherein variable groups are as defined within; for use in the inhibition of 11$g(b)HSD1 are described.  
WO/2004/011418A1
Disclosed are novel compounds of the formula (I)or a pharmaceutically acceptable salt or solvate thereof. Also disclosed is the treatment of chemokine-mediated diseases using compounds of the formula (II)  
WO/2004/007426A1
The invention relates to fullerene compounds of formula (I); in which X1, X2, X3, X4, X5, YI, Y2, V, W, F, E, R, r, n, p, and q are defined as in the specification. Also disclosed are pharmaceutical compositions containing one of the com...  
WO/2004/005239A1
The invention relates to a process for the synthesis of N-monosubstituted β-amino alcohols of formula (I) and/or an addition salt of a proton acid, wherein R1 and R2 independently represent alkyl, cycloalkyl, aryl or aralkyl, each being...  
WO/2004/002947A1
Compounds of formula (I), wherein R01 is hydrogen, C1-C8alkyl, C3-C8alkenyl or C3-C8alkynyl; or R01 is phenyl or phenyl-C1-C6alkyl, it being possible for the phenyl rings in turn to be mono- to penta-substituted by halogen and/or mono-, ...  
WO2003087035A8
2,5-bis-diamine-[1,4]benzoquinonic derivatives, having a general formula (I) have proved useful for the treatment of Alzheimer's disease; a method for preparing them and intermediates used in said method are also described. Fomula (I).  
WO/2003/106399A2
The invention provides processes for preparing N-protected β-amino aldehyde compounds which are useful as synthetic intermediates for preparing glycopeptide antibiotic derivatives. The processes include cleaving a carbon-carbon double b...  
WO2003040174A3
The present invention relates to compounds of the general formula (I): B-(CH--R<1>)n--C(=X<2>)-D and pharmaceutically acceptable salts thereof including steroisomers, to the use of the compounds for the treatment of impaired glucose tole...  
WO/2003/104186A1
A process for easily producing, from an easily available inexpensive starting material, an optically active ß-amino alcohol useful as an intermediate for medicines. An easily available &agr -substituted ketone is reacted with an optical...  
WO/2003/101933A1
Novel solid supported intermediate products of the general formula I coupled to a solid polymeric support through one or both of the R&supl groups or through the R4 group which are suitable for synthesis of heterocyclic compounds are dis...  
WO/2003/099769A1
The present invention is directed to selective LXR modulators, small molecule compounds corresponding to Formula I and is further directed to a process of treating a condition in a mammal that is modulated by LXR using a therapeutically ...  
WO/2003/097577A1
The invention relates to a filtering composition, particularly a cosmetic composition, which is used to protect a sensitive material against ultraviolet radiation, one such composition comprising an effective quantity of at least one nit...  
WO/2003/097568A1
A process for producing a 4-phenyl-4-oxo-2-butenoic ester derivative, characterized by simultaneously or continuously reacting a sulfuric ester, aromatic hydrocarbon, and maleic anhydride derivative. By the process, a 4-phenyl-4-oxo-2-bu...  
WO/2003/097575A2
The invention provides novel amino-functionalised chalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infecti...  
WO/2003/097576A2
The invention provides novel diamino-functionalised chalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infec...  
WO/2003/097574A2
The invention provides novel alkoxyaminochalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infections, is al...  
WO2001040188A8
The present invention is directed to curcumin analogs (I), wherein Y is OH, halogen, or CF3; Z is H, OH, OR1, halogen, or CF3; X1 and X2 are independently C or N; and A is as defined in the application; exhibiting anti-tumor and anti-ang...  
WO/2003/091200A1
A process for the preparation of 2-aminoketones represented by the general formula (3): (3) [wherein R is halogeno, cyano, C1-12 alkyl, or the like; R2 is hydrogen or C1-6 alkyl; n is an integer of 0 to 5; and R1 is hydrogen or C1-12 alk...  
WO2002064136A3
The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases m...  
WO/2003/086340A1
The present invention relates to organosilicone derivatives of amino hydroxybenzophenones, a process for their preparation thereof, a cosmetic compositions comprising the organosilicone derivative and the use thereof for protecting hair ...  
WO/2003/087034A1
The invention relates to 3-aminophenol derivatives of formula (I) or to their physiologically compatible, water-soluble salts, wherein R1 is identical to a radical of formula (II) or to a radical of formula (III), and to dyes that contai...  
WO2002081483A3
The present invention provides compounds with activity as inhibitors of acyl glucosaminylinositol amidases with amidase activity against S-conjugate amides, particularly mycothiol-derived S-conjugate amides. Certain of the invention comp...  
WO/2003/087035A1
2,5-bis-diamine-[1,4]benzoquinonic derivatives, having a general formula (I) have proved useful for the treatment of Alzheimer's disease; a method for preparing them and intermediates used in said method are also described. Fomula (I).  
WO/2003/086605A2
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acid group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronst...  
WO2002076939A3
Compounds having quinone and quinone analogs useful for pharmaceutical preparations have now been found which inhibit cysteine proteases, in particular, caspases and 3C-cysteine proteases. The cysteine protease inhibitors of the present ...  
WO/2003/078387A1
A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R'R' of at least 2 carbon atoms and R' and R' are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxy...  
WO/2003/068731A1
The invention relates to beta-amino ketones of general formula (I), in which R1-R4 are defined as per the description. The invention also relates to a method for the production, in particular stereoselective production of said beta-amino...  
WO/2003/059339A1
Novel tricyclic−bis−enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and&sol or treatment of cancer, Alzheimer's disease, Parkinson's disease, mul...  
WO/2003/048106A2
The invention concerns 1,3-diarylprop-2-en-1-ones and derivatives, compositions containing same and the use thereof. The invention concerns in particular novel substituted 1,3-diarylprop-2-en-1-ones having a therapeutic activity for use ...  
WO/2003/048096A1
The invention concerns products of formula (I), wherein: A represents a saturated or partly saturated cyclic hydrocarbon, optionally substituted; X is selected from the group consisting of O, N-O(R2); Ar1 represents a substituted phenyl ...  
WO2002044144A3
Radiolabeled fluorinated compounds useful for imaging in the diagnosis of Parkinson's Disease are disclosed. Methods and kits for their synthesis are also disclosed.  
WO/2003/040174A2
The present invention relates to compounds of the general formula (I): B-(CH--R?1¿)¿n?--C(=X?2¿)-D and pharmaceutically acceptable salts thereof including steroisomers, to the use of the compounds for the treatment of impaired glucose...  
WO/2003/037846A1
An improved method of producing keto acids having the formula (I), wherein R¿1? and R¿2? independently represent (a) hydrogen, wherein at least one of R¿1? and R¿2? do not stand for hydrogen, (b) branched or unbranched alkyl of 1-18 ...  
WO2002102782A3
Use of compound of formula (I), wherein (a) is (b) or (c) and wherein the symbols are as defined, or a pharmaceutically-acceptable and-cleavable ester, or acid addition salt thereof, for the preparation of a medicament for promoting the ...  
WO/2003/033447A1
Compounds represented by the following general formula (I): R−Y−(−X−Phe−COCH2COCnF2n&plus 1)m (I) wherein R represents hydrogen, alkyl, phenyl or a group capable of binding to a protein, a peptide, an amino acid, a nucleic acid...  
WO/2003/029186A1
Compositions comprising (±)-2-((dimethylamino)methyl)cyclohexanone, a transition-metal salt, and an organic solvent and methods ofpreparing (±)-cis-2-((dimethylamino)methyl)-l-(aryl)cyclohexanols, in particular (±)-cis-2-((dimethylami...  
WO2002034708A3
The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these composition...  
WO/2003/018535A2
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compo...  
WO/2003/017955A1
The invention concerns dyeing agents for keratinous fibers based on a developer-coupler combination, characterized in that they contain at least a 3-aminophenol derivative of formula (I) or a salt thereof, water-soluble and physiological...  
WO/2003/018536A1
The invention provides 1,2-substituted cyclic compounds useful for treatment of diseases or disorders arising from abnormal or inappropriate cell proliferation, such as tumour growth, tumour metastasis and associated angiogenesis, as wel...  
WO/2003/015761A1
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO2002076995A3
Compounds of formula (I), wherein m, R, R1 and R3 to R6 are as defined in the specification, m, is 1, 2 or 3 and X is O or a direct bond, and the corresponding unphosporylated compounds have interesting properties, e.g. immunosuppressive...  
WO/2003/006420A1
The present invention is directed to a method of converting an aryl compound to an aniline compound, comprising the steps of (1)providing an aryl compound containing a halide group or a sulfur-containing group; (2) reacting the aryl comp...  
WO2001062705A3
A compound of the formula (I) wherein X1 is bond or -O(CH2)m- (in which m is an integral number of 1, 2 or 3); X2 is bond, -(CH2)n-, etc. (in which n is an integral number of 1, 2 or 3); R1 is hydrogen or amino protective group; R2 is hy...  
WO/2003/002511A1
(−)−3−[3−[(1R,2R,4S)−bicyclo[2.2.1]hept−2−ylox y]−4−methoxyanilino]−2−methyl−2−cyclopenten−1 one or a hydrate or solvate thereof&semi or a medicinal composition containing any of these.  
WO/2002/102782A2
Use of compound of formula (I), wherein (a) is (b) or (c) and wherein the symbols are as defined, or a pharmaceutically-acceptable and-cleavable ester, or acid addition salt thereof, for the preparation of a medicament for promoting the ...  
WO2002042248A3
The present invention relates to naphthalene derivatives of formula (I), wherein X is S, S(O), S(O)2, S(O)2NH, P(O)OCH3, P(O)OH, NH, N(CH3), NHC(O)NH, C(O), C(O)O, NHC(O), CH(OH), CH=N, CH=CH, CH2NH, C(=NH); R<1> is aryl or heteroaryl; R...  

Matches 301 - 350 out of 3,207