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Patent Searching and Data


Matches 401 - 450 out of 3,275

Document Document Title
WO2001098265A3
The present invention describes a new process for obtainment of the cetamine enantiomers, form the racemic cetamine resolution with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers...  
WO/2002/058630A2
Primary intermediate for hair coloring compositions for oxidative dyeing of hair is 4-amino-2-(1-hydroxy-ethyl)-phenol.  
WO/2002/057211A1
Symmetrically disubstituted aromatic compounds and pharmaceutical compositions containing such compounds that inhibit and/or modulate the activity of poly(ADP-ribose) glycohydrolase, also known as PARG, are described. The invention is al...  
WO/2002/057199A1
The invention relates to a process for carrying out a homogeneously catalyzed C-C coupling reaction between an optionally substituted (hetero)aromatic bromide compound and a second reactant, which is chosen from the group of olefins in w...  
WO2001040188A9
The present invention is directed to curcumin analogs (I), wherein Y is OH, halogen, or CF3; Z is H, OH, OR1, halogen, or CF3; X1 and X2 are independently C or N; and A is as defined in the application; exhibiting anti-tumor and anti-ang...  
WO/2002/053523A1
A tropolone derivative represented by the formula (I) which has retinoid activity and is useful as an active ingredient for medicines [R?1¿ to R?4¿ each represents hydrogen, alkyl, or alkoxy; ring Ar represents an aryl ring or heteroar...  
WO/2002/053537A1
The present invention relates to a process for preparing (±)-trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidi ne of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX') methods for ...  
WO2001062257A3
Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective ...  
WO/2002/044144A2
Radiolabeled fluorinated compounds useful for imaging in the diagnosis of Parkinson's Disease are disclosed. Methods and kits for their synthesis are also disclosed.  
WO/2002/044139A1
The invention concerns compounds of formula (I), wherein: A is a group of formula (a) or (b), their salts or solvates, pharmaceutical compositions containing them, a method for preparing them and intermediates used in said method. The co...  
WO/2002/042248A2
The present invention relates to naphthalene derivatives of formula (I), wherein X is S, S(O), S(O)¿2?, S(O)¿2?NH, P(O)OCH¿3?, P(O)OH, NH, N(CH¿3?), NHC(O)NH, C(O), C(O)O, NHC(O), CH(OH), CH=N, CH=CH, CH¿2?NH, C(=NH); R?1¿ is aryl ...  
WO/2002/042254A1
The present invention relates to a process of producing carbonyl a-substituted nitrogen-containing compounds, which comprises reacting a-halo-ketone or a-halo-aldehyde with primary amine, secondary amine or heterocycle compound containin...  
WO2001049651A3
The invention relates to aminomethyl-phenyl-cyclohexanone derivatives, to methods for the production thereof, to the use of aminomethyl-phenyl-cyclohexanone derivatives for producing medicaments, and to medicaments containing aminomethyl...  
WO/2002/038120A1
The present invention relates to photo-labile pro-fragrance conjugates comprising: a) a photo-labile unit which upon exposure to electromagnetic radiation is capable of releasing a pro-fragrance unit; and b )a pro-fragrance unit, which w...  
WO2002000609A3
Formula (I) compounds are described where the groups are as defined in the description, as well as processes for their preparation and their use as medicaments, particularly for the preparation of medicaments with phosphodiesterase IV in...  
WO/2002/034708A2
The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these composition...  
WO/2002/028815A1
A compound of the formula in which R?1¿ and R?2¿ are each hydrogen or C¿1-4? alkyl, or R1 and R2 together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl or morpholino group...  
WO/2002/028808A1
This invention provides analogs of triptycene which are useful as anticancer drugs, as well as for other uses. The potency of these compounds is in a similar magnitude as daunomycin, a currently used anticancer drug. Each compound of the...  
WO2001096278A3
Accordingly, the present invention provides a process for the preparation of a compound of formula (I) or a single enantiomer thereof, or a salt or a solvate thereof, wherein W is a chiral auxiliary or hydrogen and P<1> and P<2> are each...  
WO2001060781A3
For use in the inhibition of retinoic acid metabolism, diphenyl compounds of formula (I).  
WO/2002/020460A1
Novel arylamine compounds of the general formula (1), and an organic electroluminescent device whose organic compound layer contains a novel arylamine compound described above: (1) (wherein R?1¿ and R?2¿ are each independently alkyl, a...  
WO/2002/018319A1
The present invention relates to a process for the preparation of N-arylanthranilic acids, and a process for the preparation of N-aryl anthranilic esters, amides, and hydroxamic esters.  
WO2001068654A3
A diverse set of tubulin binding ligands have been discovered which are structural by characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for m...  
WO/2002/010103A1
A method for the synthesis of an $g(a),$g(b)-unsaturated ketone useful for making substituted 1,4-dihydropyridines is described by reacting an aldehyde with pyrrolidine and then adding a ketone followed by trifluoroacetic acid at low tem...  
WO/2002/008170A1
A process for producing optically active $g(a)-hydroxy-$g(b)-aminocarboxylic acid derivatives. $g(a)-Aminoketone derivatives (4) are successively halogenated, reduced and hydrolyzed to thereby efficiently produce $g(a)-amino-$g(a)', $g(a...  
WO/2002/008197A1
The invention relates to novel biphenyl carboxamides of formula (I), wherein A, R, Z, X, Y, m and n have the meanings given in the description, to multiple methods for producing these substances, to their use for combating unwanted micro...  
WO/2002/006210A1
This invention provides compounds of Formula (I) having the structure wherein, B is a, b, or c; or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance o...  
WO2001046125A3
Substituted phenantheren-9, 10-diones in accord with structural diagram (I), compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In ...  
WO/2002/002516A2
The present invention is a series of novel and effective inhibitors of integrase, an essential in the life cycle of retroviruses. These compounds were designed to have a restricted conformation for the determination of the integrase bind...  
WO/2002/002507A1
The invention relates to an oxidative colouring agent for keratin fibres, in particular hair, based on a developing agent-coupling agent combination, which contains as a developing agent, at least one 2-hydroxy-5-amino-biphenyl derivativ...  
WO/2002/000586A1
The present invention relates to propanedione derivatives represented by general formular (A), and their use as UV-absorbent. Wherein R?1¿ is substituted aromatic ring, optionally substituted heteroaromatic ring, or optionally substitut...  
WO/2002/000609A2
Formula (I) compounds are described where the groups are as defined in the description, as well as processes for their preparation and their use as medicaments, particularly for the preparation of medicaments with phosphodiesterase IV in...  
WO/2001/098251A1
New compounds of formula (I) are described: The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders.  
WO/2001/098265A2
The present invention describes a new process for obtainment of the cetamine enantiomers, form the racemic cetamine resolution with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers...  
WO/2001/096278A2
Accordingly, the present invention provides a process for the preparation of a compound of formula (I) or a single enantiomer thereof, or a salt or a solvate thereof, wherein W is a chiral auxiliary or hydrogen and P?1¿ and P?2¿ are ea...  
WO/2001/094357A1
New spisulosine derivatives of use in treating tumors are of the formula (I) wherein: each X is the same or different, and represents H, OH, OR', SH, SR', SOR', SO¿2?R', NO¿2?, NH¿2?, NHR', N(R')¿2?, CN, halogen, C(=O)H, C(=O)CH¿3?,...  
WO/2001/092202A1
This invention relates to the novel use of dianilino squarates in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).  
WO/2001/089504A1
Excellent 12-lipoxygenase inhibitors containing as the active ingredient tropolone derivatives of the general formula (1) or salts thereof. In said formula wherein R?1¿ is hydrogen or optionally substituted C¿3-10? alkenyl; R?2¿ is hy...  
WO/2001/078713A1
Compounds of general formula (I). wherein rings B, C, D and E may be present or not and, when present, are combined with A as A+C, A+E, A+B+C, A+B+D, A+B+E, A+C+E, A+B+C+D or A+B+C+D+E, rings B, C and E being aliphatic whereas ring D may...  
WO/2001/070675A2
The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell pr...  
WO2001062705A8
A compound of the formula (I) wherein X1 is bond or -O(CH2)m- (in which m is an integral number of 1, 2 or 3); X2 is bond, -(CH2)n-, etc. (in which n is an integral number of 1, 2 or 3); R1 is hydrogen or amino protective group; R2 is hy...  
WO/2001/068654A2
A diverse set of tubulin binding ligands have been discovered which are structural by characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for m...  
WO/2001/064208A1
This invention relates to the novel use of dianilino squarates in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).  
WO/2001/062257A2
Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective ...  
WO/2001/062705A2
A compound of the formula (I) wherein X¿1? is bond or -O(CH¿2?)¿m?- (in which m is an integral number of 1, 2 or 3); X¿2? is bond, -(CH¿2?)¿n?-, etc. (in which n is an integral number of 1, 2 or 3); R¿1? is hydrogen or amino prote...  
WO2001010816A3  
WO/2001/060781A2
For use in the inhibition of retinoic acid metabolism, diphenyl compounds of formula (I).  
WO/2001/049651A2
The invention relates to aminomethyl-phenyl-cyclohexanone derivatives, to methods for the production thereof, to the use of aminomethyl-phenyl-cyclohexanone derivatives for producing medicaments, and to medicaments containing aminomethyl...  
WO/2001/047866A1
The invention relates to substituted 1 and 2 naphthol Mannich bases, a method for the production thereof, medicaments containing said compounds and the use of said compounds in the production of medicaments.  
WO/2001/046125A2
Substituted phenantheren-9, 10-diones in accord with structural diagram (I), compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In ...  

Matches 401 - 450 out of 3,275