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Matches 1 - 50 out of 8,769

Document Document Title
WO/2019/175175A1
Method of purifying an alkali metal salt of a compound of the general Formula (I) or Formula (II) R1R2N-CHR3-COOH (I) or R1R2N-CHR3CHR3-COOH (II) wherein R1, R2 and R3 are independently H, an alkyl, an alkenyl, or a hydroxyalkyl radical ...  
WO/2019/175169A1
The application relates to a process for drying a composition comprising an alkali metal salt of a compound of general formula (I) R1 R2N- CHR3-COOM or formula (II) R1 R2N-CHR3CHR3-COOM, in particular N,N- dimethyl glycinate salt, and th...  
WO/2019/168269A1
The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using ...  
WO/2019/157426A1
The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermedia...  
WO/2019/154151A1
The present invention relates to an intermediate compound of formula II-1 or formula II-2 or a salt thereof, and a preparation method therefor. The present invention further relates to a process for synthesizing a compound of formula I b...  
WO/2019/137083A1
Disclosed in the present invention are a one-step process for producing a nylon 5X salt and a prepared high-purity nylon 5X salt. The process comprises: subjecting a lysine fermentation liquid to ion exchange and desorption to obtain a p...  
WO/2019/135189A1
The present invention provides an improved process for preparation of the L-threo-(2S,3R)-3-(3,4-dihydroxyphenyl)serine (I) or a salt thereof, which is known as Droxidopa; comprising (a) recovery of the by-product compound (V) (as descri...  
WO/2019/118072A1
There is disclosed a process for the purification of long chain amino acids by recrystallization in an aqueous solution of organic carboxylic acid in the absence or presence of solvent, comprising: (1) dissolving a long chain amino acid ...  
WO/2019/110371A1
The application relates to a process for the synthesis of organic sulfonic acid salts of amino acid esters comprising the steps of (i) reacting at least one lactam with at least 3 carbon atoms in the lactam ring with at least one organic...  
WO/2019/080155A1
The present invention relates to a conjugate salt of N,N-dimethylglycine and a metal organic acid, a preparation method therefor, and an application thereof. The conjugate salt of N,N-dimethylglycine and a metal organic acid has the foll...  
WO/2019/080009A1
Disclosed are an N,N-dimethylglycine organic acid polyvalent metal ion compound salt or a solvate thereof, and an application thereof in preparation of novel feed additives and feeds. Also disclosed is a feeding composition comprising th...  
WO/2019/066412A1
The present invention relates to a method for preparing a glutamate-based surfactant. More specifically, the present invention provides a method for preparing a glutamate-based surfactant, the method being very economical and being capab...  
WO/2019/057627A1
The present invention relates to a method for purifying polyaspartic acid ester compositions and to the provision of polyaspartic acid ester compositions that contain 0.01 to < 2% by weight fumaric acid dialkyl esters.  
WO/2019/037591A1
The present invention relates to a melphalan hydrochloride crystal form, a preparation method therefor and an application thereof. The preparation method is convenient to operate, has a short reaction period, reduces environmental pollut...  
WO/2019/040177A1
There is disclosed a process for the purification of long chain amino acids by recrystallization in an aqueous solution of organic carboxylic acid in the absence or presence of solvent, comprising: (1) dissolving a long chain amino acid ...  
WO/2019/034114A1
Provided is a composition containing L-carnitine-β-hydroxybutyrate wherein the L-carnitine and β-hydroxybutyrate compounds in the molecule exist in the form of an intramolecular salt, and the composition is used for losing weight and p...  
WO/2018/033883A3
The invention provides for a synthesised ester intermediate of formula 1. Formula 1 Wherein and wherein R may be a saturated or unsaturated fatty acid (C12-C20).  
WO/2018/231747A3
Methods of synthesizing fluoroquinolones such as ciprofloxacin are provided. The methods utilize affordable materials, reduce the number of synthesis steps and provide high yields.  
WO/2019/016745A1
Aspects of the present application relate to process for the preparation of Pyrrolidine derivatives useful as key intermediates for active ingredients. Specific aspects relate to alternate process for the preparation of Upadacitinib inte...  
WO/2019/013954A1
There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) mixing the mixed amide derivatives with an aqueous solution of ammonia or ammonium hydroxide in the presence or absence...  
WO/2019/010016A1
There is disclosed a process for the production of long chain amino acid and long chain dibasic acid, comprising: (1) reacting long chain keto fatty acid with hydroxylamine or subjecting keto fatty acid to an ammoximation reaction to yie...  
WO/2019/007944A1
The present invention relates to a methylglycine-N,N-diacetic acid trisodium salt in the form of a crystal, comprising a crystalline modification referred to as crystal type III characterized by the below reflections when analyzed with X...  
WO/2019/007943A1
The present invention relates to a process for the preparation of a solid composition of an amino acid diacetic acid compound wherein the amino acid diacetic acid compound is methyl glycine-N,N-diacetic acid or a salt thereof, or glutami...  
WO/2019/002022A1
The present invention is directed towards a process for manufacturing a complexing agent, said process comprising the steps of (a) Providing a nitrile according to general formula (I a) or (I b) (formula I a, I b) With M being selected f...  
WO/2019/002685A1
The present invention relates to a process for in situ the preparation of mixtures of chelating agents by catalyzed reactions of diethanolamine derivatives with maleic acid and then with 2-halocarboxylic acid, to mixtures of chelating ag...  
WO/2019/005628A1
There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) recovering alkylamine by distilling or by extracting with an extractant solvent; (2) adding an acid and an extractant s...  
WO/2019/005630A1
There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) recovering alkylamine from an aqueous solution of an alkali hydroxide hydrolysis of the mixed amide derivatives by dist...  
WO/2019/005629A1
There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) adding water and an extractant solvent to the aqueous suspension of an acid hydrolysis of the mixed amide derivatives t...  
WO/2019/002684A1
The present invention relates to a process for the in situ preparation of mixtures of chelating agents by catalyzed reactions of diethanolamine with maleic acid and then with 2-halocarboxylic acid, mixtures obtainable using said process ...  
WO/2019/005631A1
There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) cooling the hydrolysis solution to crystallize and separate alkali salt of long chain dibasic acid to provide an aqueou...  
WO/2018/226841A1
Zwitterionic monomers, camitine-derived zwitterionic polymers, carnitine ester cationic monomers, carnitine ester cationic polymers, conjugate compositions including a carnitine-derived zwitterionic polymer, and related compositions' and...  
WO/2018/226340A1
A method for preparing diphenol compounds includes adding a hydroxyphenyl carboxylic acid, a tyrosine ethyl ester, hydroxybenzotriazole hydrate and a solvent and stirring to produce a first solution, EDCI HCI is added to the first soluti...  
WO/2018/212162A1
The purpose of the present invention is to provide a method for easily producing a diaminobenzene compound and a benzimidazole compound at low cost. The present invention provides a method for producing a diaminobenzene compound or N-pro...  
WO/2018/206728A1
The invention relates to the use of a precursor for the production of carbon-11-labelled amino acids or derivatives thereof. According to the invention, the precursor is a compound of formula I: (formula I), where R1 and R2 are selected ...  
WO/2018/207693A1
A 1–amino cyclopropane carboxylic acid nonhydrate can be produced as a result of: using a tertiary amine to treat a 1–amino cyclopropane carboxylic acid hydrochloride in the presence of a C3–C4 alcohol and water; maintaining the re...  
WO/2018/207694A1
A 1–amino cyclopropane carboxylic acid nonhydrate can be produced as a result of: using a tertiary amine to treat a 1–amino cyclopropane carboxylic acid hydrochloride in the presence of a C3–C4 alcohol and water; maintaining the re...  
WO/2018/208677A1
Embodiments of the present disclosure are related to improved processes for making L-ornithine phenylacetate without using any silver salts or forming any L-ornithine intermediate salts, such as a benzoate salt. The present processes may...  
WO/2018/191999A1
The present invention relates to a process for preparing perindopril, the process mainly involving oxidizing ethyl 3-ketohexanoate as a raw material to synthesize ethyl 2-ketovalerate, then subjecting same to condensation ammoniation and...  
WO/2018/187324A1
The subject invention relates to a process of prepating (R)-3-hydroxybutyric acid or a salt thereof by one-step fermentation with a nonpathogenic microorganism. The fermentation of (R)-3-hydroxybutyric acid was performed by supplying wit...  
WO/2018/174826A1
This invention relates to a method for producing an alkenyl 1 -aminocyclopropane-1 -carboxylic acid of Formula I wherein R1 is a protecting group, n is an integer between 1 and 10, and A and B are chiral centres such that when A is S, B ...  
WO/2018/164662A1
A resveratrol ester has the following structure: (I). R1, R2 and R3 are H or (II). Each R4 is independently a carbon chain of 2 to 4 carbon atoms comprising a terminal carboxylic acid moiety, a carbon chain of 1 to 5 carbon atoms compris...  
WO/2018/157842A1
The present invention provides a use of 2-(substituted phenylamino)benzoic acid FTO inhibitor in treating leukemia.  
WO/2018/143492A1
The present invention relates to an aminobenzaldehyde derivative and an amino acid chiral extractant comprising the same, wherein the amino acid chiral extractant can allow amino acids in an aqueous solution to be extracted with high chi...  
WO/2018/139311A1
[Problem] To provide a novel diamine compound with which it is possible to synthesize a polyimide compound having high solubility in organic solvents and high melt moldability. [Solution] This diamine compound is characterized by being r...  
WO/2018/116203A1
The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, ...  
WO/2018/114841A1
The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) ads...  
WO/2018/115434A1
The invention relates to a method for the production of acetylsalicylic acid lysinate, optionally lysine acetylsalicylate · glycine, comprising the following steps: a) providing a solution of acetylsalicylic acid in ethanol; b) providin...  
WO/2018/090963A1
The invention provides a method for preparing a lisinopril intermediate, comprising: treating (R)-hydroxy-4-phenylbutyrate with sulfonyl chloride in an organic solvent in the presence of a base to obtain a solution of sulfonate; reacting...  
WO/2018/090670A1
The present invention relates to a method for preparing a droxidopa intermediate (2S,3R)-3-(3,4-dibenzyloxyphenyl)-2-dibenzylamino-3-hydroxyp ropionate, comprising carrying out asymmetric hydrogenation to 3-(3,4-dibenzyloxyphenyl)-2-dibe...  
WO/2018/086053A1
The present invention discloses a γ-aminobutyric acid semihydrate crystal. The formula of the crystal is C4H9NO2·0.5H2O. The present invention further discloses a preparation method for the γ-aminobutyric acid semihydrate crystal, whe...  

Matches 1 - 50 out of 8,769