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Matches 1 - 50 out of 8,625

Document Document Title
WO/2017/220308A1
Process for making a powder or granule containing at least one chelating agent selected from alkali metal salts of methyl glycine diacetic acid (MGDA) and glutamic acid diacetate (GLDA) and iminodisuccinic acid (IDS), said process compri...  
WO/2017/199227A1
The present invention relates to a simple economical process for the preparation of 3,4- dihydroxy-2-methyl benzoic acid C1-4 alkyl ester and novel intermediates for use in the process.  
WO/2017/183539A1
[Problem] To provide a compound that can be used on an industrial scale. [Solution] A compound represented by general formula (4) or a base adduct thereof. (In the formula, R3 and R4 independently represent a hydrogen atom or the like.)  
WO/2017/174413A1
The present invention is directed towards mixtures comprising (A) 90 to 99.999 % by weight of racemic methyl glycine diacetic acid (MGDA) or of MGDA with predominantly the L-isomer in an enantiomeric excess of up to 9.5% or their respec-...  
WO/2017/168313A1
The present invention provides an improved process for preparation of L-threo-(2S,3R)-3-(3.4- dihydroxyphenyl)serine (I) (Droxidopa) and its salts; comprising (a) reaction of the aldehyde compound (III) (as described herein) with Metal c...  
WO/2017/154738A1
The present invention addresses the problem of providing a novel method for producing an optically active amine compound that is useful as an intermediate for a medicine, an agrochemical, an electronic material and the like. A method for...  
WO/2017/145097A3
The invention relates to amino acid and peptide conjugates, methods for making amino acid and peptide conjugates, conjugates produced by the methods, and pharmaceutical compositions comprising the conjugates. Methods of eliciting immune ...  
WO/2017/137955A1
The present invention relates to novel chiral 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine (5) and racemic 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine () and its use in improved and ...  
WO/2017/133913A1
The present invention relates to a process for the N-alkylation of amines by reacting an amine with an orthocarboxylic acid ester and with hydrogen in the presence of a hydrogenation catalyst.  
WO/2017/134212A1
The present invention relates to a one-pot process for the preparation of trans-4-amino-l-cyclohexanecarboxylic acid derivatives where the trans ratio is more than 75% by reaction of a 4-aminobenzoic acid derivative using an appropriate ...  
WO/2017/132178A3
The present disclosure provides new salts of 5-aminolevulinic acid (5-ALA) and new salts of 5-ALA esters, their preparation, formulation and use as photosensitizing agents in photodynamic therapy, diagnosis and cosmetic cares.  
WO/2017/130687A1
[Problem] To make the size and shape of obtained particles uniform. Proposed is a mode by which the power cost is not increased. [Solution] A method of producing particles for which contact is brought about between a plurality of dissimi...  
WO/2017/118871A1
The present invention relates to a method for the fermentative production of L- methionine and /or its derivatives comprising the step of i) culturing a microorganism optimised for the fermentative production of methionine in an appropri...  
WO/2017/113428A1
Disclosed are a method for synthesizing a number of aliphatic cyanoamino acids and application of the cyanoamino acids in bioorthogonal Raman detection. The aliphatic cyanoamino acids are methionine derivatives and lysine derivatives. Th...  
WO/2017/107907A1
The present invention relates to a condensed ring γ-amino acid derivative and a medical use thereof, and in particular relates to the condensed ring γ-amino acid derivative as shown in formula (I), or a stereisomer, a solvate, a metabo...  
WO/2017/108884A1
It is provided a compound of formula (I'); wherein R5 is selected from the group consisting of -H, -OM, -COOM, -NH2, -SO3M, (C1-C4)alkyl, and halogen; and A is a radical having at least 3 C atoms selected from the group consisting of: i)...  
WO/2017/102483A1
Process for manufacturing a crystalline alkali metal salt of the general formula (I) [R1-CH(COO)-N(CH2-COO)2]M1 3 (I) wherein M1 is selected from alkali metal cations, same or different, R1 is selected from C1-C4-alkyl and CH2CH2COOM1, c...  
WO/2017/097657A1
Process for manufacturing granules of at least one alkali metal salt of aminopolycarboxylic acid (A), comprising the steps of (a) providing an aqueous slurry of alkali metal salt of aminopolycarboxylic acid (A), (b) maintaining said aque...  
WO/2017/089607A1
The invention relates to y-amaninamide (1; x = 0, 1 or 2), y-amaninamidic acid (2; x = 0, 1 or 2), and γ-amaninamidic hydroxamic acid (3; x = 0, 1 or 2), novel derivatives of γ-amanitin (4), and methods and novel building blocks for th...  
WO/2017/088819A1
The present application relates to a preparation method of intermediate compounds with formula II and formula III of a compound (N-{3-[3-(9H-purin-6-yl) pyridin-2-ylamino]-4-chloro-2-fluorophenyl}-3-fluoropropane- 1-sulfonamide) for regu...  
WO/2017/090354A1
[Problem] To provide an aromatic compound methylation method, in which a reaction substrate that serves as a raw material can be synthesized easily, and which can be employed as a method for producing a [11C]-labeled tracer for PET use. ...  
WO/2017/088218A1
A method of co-producing a long chain amino acid and a dibasic acid, comprising the following steps: (a) reacting a keto acid derivative with hydroxyl amine in a solvent or performing an ammoxidation oximation reaction to generate a hydr...  
WO/2017/081206A1
The invention relates to an industrially viable and advantageous process for the preparation of (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid, having the following formula (I) generally known as Droxidopa, or of interme...  
WO/2017/070794A1
The present application relates to processes for the preparation of the aspergillomarasmine A (AM-A) compound and analogs and derivatives thereof. The features of this process involves the use of a cyclic activated serine synthon in the ...  
WO/2017/066901A1
Disclosed is a process of oxidizing an alcohol of formula ROH (I), wherein R represents a saturated or unsaturated, linear, branched or cyclic C3-C50 hydrocarbon group which is optionally substituted with a heteroatom, characterized in t...  
WO/2017/055745A1
The present invention relates to a composition which comprises at least one α,ω-amino-alkanoic acid or ester and at least one alkanoic ester or acid, characterised in that: the α,ω-amino-alkanoic acid or ester has formula H2N-(CH2)n-...  
WO/2017/048528A1
Disclosed are a variety of amphoteric compounds containing a quaternary nitrogen group, a covalently bound counterion, and an ester or amide group. These amphoteric compounds can be advantageously prepared via a chemoenzymatic green proc...  
WO/2017/036934A1
The invention relates to a method for obtaining a carboxylic acid from a fermentation broth and to a system which is designed to carry out the method. The method has the following steps: a) separating the biomass from the fermentation br...  
WO/2017/021445A1
Tilidine isomerization and crystallization process, comprising providing a reaction mixture comprising cis-tilidine, a dicarboxylic acid, water and an alcohol having 3 to 6 carbon atoms; maintaining the reaction mixture at a temperature ...  
WO/2017/023774A9
Prodrugs of glutamine analogs, such as prodrugs of aza-serine, and 6-diazo-5-oxo-norleucine (DON), and 5-diazo-4-oxo-L-norvaline (L-DONV) are disclosed.  
WO/2017/023774A1
Prodrugs of glutamine analogs, such as prodrugs of aza-serine, and 6-diazo-5-oxo-norleucine (DON), and 5-diazo-4-oxo-L-norvaline (L-DONV) are disclosed.  
WO/2017/019791A1
Provided is a process for preparing (S)-Pregabalin  
WO2017009753A1
The present invention provides an improved process for the preparation of 3-(4-chlorophenyl)-3- cyanopropanoic acid (compound (A)) and further its transformation to Baclofen (I). The process comprises reaction of compound (II) with Glyox...  
WO/2016/207266A1
The present invention relates to a process to prepare N,N'-di(2-hydroxybenzyl) ethylenediamine-N,N'-diacetic acid and salts thereof (HBED) comprising a reaction between formaldehyde, ethylenediamine diacetic acid or a salt thereof (EDDA)...  
WO/2016/207265A1
The present invention relates to a process to prepare N,N'-di(2-hydroxybenzyl) ethylenediamine-N,N'-diacetic acid and salts thereof comprising a reaction between formaldehyde, ethylenediamine diacetic acid or a salt thereof and phenol at...  
WO/2016/203500A3
The present invention provides (4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid ethyl ester as well as method of preparing said compound. The present invention provides methods of synthesizing sacubitril involving (4S)-(p-phe...  
WO/2016/202252A1
The present invention relates to the field of compound synthesis and discloses a method for synthesizing D-para-hydroxyphenylglycine methyl ester. The method comprises the steps of: (1) in the presence of thionyl chloride, carrying out a...  
WO/2016/197580A1
The present invention discloses a method of synthesizing an α-amino acid derivative with α-alkyl side chain substitution. The method comprises: reacting an alkene with 9-bbn at 0-80˚C for 0.5-12 h, and then adding an imine to react at...  
WO/2016/193740A1
The invention relates to a process for the preparation of one or more intermediate chemical compounds useful in the preparation of non-ionic contrast agents wherein the process is carried out continuously using one or more flow procedures.  
WO/2016/194586A1
A radioactively labeled compound production device (100) is a production device for producing a radioactively labeled compound by introducing a radioactive isotope into a non-radioactively labeled precursor compound. The production devic...  
WO/2016/179692A1
The present disclosure provides a process for preparing iminodisuccinic acid salts using maleic anhydride, aspartic acid, and a base in water. In an example, maleic anhydride and aspartic acid are mixed with a base to form a slurry, pref...  
WO/2016/180664A1
Process for making a chelating agent according to the general formula (I), R1-CH(COOX1)-N(CH2COOX1)2 wherein R1 is selected from hydrogen, C1-C4-alkyl, phenyl, benzyl, CH2OH, and CH2CH2COOX1, X1 is (ΜχΗ1-χ), M being selected from alk...  
WO/2016/173960A1
The invention relates to an optimized synthesis of pregabalin and additional 4-aminobutane acids using an improved method for producing conjugated nitroalkenes. This is achieved by a nitro-aldol reaction of an aliphatic aldehyde with a n...  
WO/2016/171240A1
The present invention addresses the problem of providing an excellent method for producing an excellent therapeutic agent. The solution of the present invention is as shown in the following scheme. (In the formulae, R1 represents a C1-C6...  
WO/2016/164748A1
This document describes a process for the high purity and high concentration recovery of monovalent products via continuous ion exchange from aqueous solution for further downstream purification.  
WO/2016/164767A1
The present disclosure relates to methods for separating at least one amine chosen from diamines and omega-aminoacids from a feed mixture using a simulated moving bed (SMB) adsorptive technology.  
WO/2016/155596A1
Disclosed is a method of synthesizing a 3-halo-D-alanine methyl ester or an acid salt thereof. By reacting a D-serine methyl ester or an acid salt thereof and a halogenation reagent in an organic solvent, the method prepares a 3-halo-D-a...  
WO/2016/153064A1
[Problem] To provide a novel diamine for imparting a thin film that has not only exceptional flexibility and transparency, but also low retardation. [Solution] Provided are: a diamine characterized by being represented by formula (1-1); ...  
WO/2016/151990A1
The present invention relates to novel tertiary alcohol derivatives substituted with aryl and trifluoromethyl, and optical isomers thereof. In addition, the present invention also relates to methods for the preparation and use as enantio...  
WO/2016/150953A1
The present invention relates to a process for synthesis of 4,5,6,7- tetrahydroisoxazolo[5,4-c]pyridin-3-ol abbreviated THIP, having the INN name gaboxadol, starting from pyrrolidin-2-one. The process comprises a new direct process to ob...  

Matches 1 - 50 out of 8,625