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Matches 1 - 50 out of 13,945

Document Document Title
WO/2018/068757A1
New anticancer and anti-obesity agents based on the cyclic peptide compounds are disclosed, and its preparation and application method for treating cancer and obesity diseases are also disclosed.  
WO/2018/067401A1
Eflornithine is an agent that can be used to treat glioma, especially glioma of WHO Grade II or Grade III such as anaplastic glioma. Eflornithine can suppress or prevent mutations in glioma which can cause the glioma to progress to a hig...  
WO/2018/064755A1
A transfection reagent composition comprising: 30-60MOL% of an cationic lipid, or pharmaceutical acceptable salt thereof; 10-60 MOL% structural lipid; a sterol and 0.1 to about 10MOL% of a stabilizing agent is provided. The reagent is pa...  
WO/2018/059279A1
Disclosed is a method for synthesizing a novel chiral ligand, a metal chelate, a variety of non-natural amino acids, Maraviroc and a key intermediate thereof. In the invention, (R)-2-methyl proline is selected and used as a starting raw ...  
WO/2018/059427A1
Disclosed is a method for preparing 2-(2-(4-fluorobenzoyl)phenylamino)-3-(4-(2-(9H-carbazol-9-yl )ethoxy)phenyl)propanoic acid. In the method 9-carbazole ethanol mesylate and methyl 2-[2-(4-fluorobenzoyl)phenyl)amino]-3-(4-hydroxyphenyl)...  
WO/2018/057290A1
The invention relates to a method for synthesizing amino acids or amino acid derivatives involving cross metathesis of functionalized olefins and a tandem amination-reduction process. Amino acids and amino acid derivatives present many i...  
WO/2018/050795A1
The present invention relates to a process for preparing a carotenoid mono-ester of the formula (I), including the stereoisomers of formula (I), wherein, R1 is e.g. hydrogen, C1-C20-alkyl, C2-C20-alkenyl, C4-C20-alkdienyl, C6-C20-alktrie...  
WO/2018/050046A1
Disclosed are a fused tricyclic γ-amino acid derivative and a medical use thereof, in particular, the present invention relates to a fused cyclic γ-amino acid derivative as shown in general formula (I), or a stereoisomer, solvate, meta...  
WO/2018/048882A1
The present invention provides a composition comprising the compound having the structure: Formula or a salt of the compound; 4-amino-2- [19F] -fluorobenzoic acid or a salt of 4-amino-2- [19F] -fluorobenzoic acid; and at least one accept...  
WO/2018/044987A1
The present disclosure relates to thiopicolinamides of Formula I and their use as fungicides.  
WO/2018/044991A1
This disclosure relates to thiopicolinamides of Formula I and their use as fungicides.  
WO/2018/041804A1
The present invention relates to a process for preparing 3-(2-hydroxybenzoyloxy)-4-(trimethylammonio)butyrobetaine hydrochloride of the formula (I), wherein the process comprises the reaction of 3-hydroxy-4-(trimethylammonio)butyrobetain...  
WO/2018/035610A1
The present invention provides 18F-labeled amino acids or derivatives thereof having formula (I) and methods of making same, which can be suitable for PET imaging: (Formula (I)).  
WO/2018/037115A1
The present invention provides an aqueous composition comprising a silicon complex. The composition comprises (i) a monomeric organosilanolate that comprises 1 to 3 oxygen atoms per silicon atom, said organosilanolate being of formula (R...  
WO/2018/033883A2
The invention provides for a synthesised ester intermediate of formula 1. Formula 1 Wherein and wherein R may be a saturated or unsaturated fatty acid (C12-C20).  
WO/2018/025892A1
The purpose of the present invention is to provide a novel polymerizable triptycene derivative compound, which has a structure in which three benzene rings arranged around barrelene having a triptycene skeleton are capable of balanced ro...  
WO/2018/023116A1
Provided herein are isotopically labeled reagents, including isotopically labeled small molecules and peptides, that can be used to detect and/or quantify β-N-methylamino-L-alanine (BMAA) in a sample. The reagents can be used as stable ...  
WO/2018/021010A1
Provided is a method for producing glycine with which it is possible to obtain glycine at a higher yield than with conventional methods, when glycine is synthesized from glycinonitrile. The method for producing glycine is characterized i...  
WO/2018/021338A1
The present invention is a method for producing a specific α-amino acid in which a specific α-amino acid amide and water are reacted with each other in the presence of a zirconium compound, wherein the zirconium compound contains zirco...  
WO/2018/014140A1
Disclosed herein is a method for multimodal imaging during a medical procedure using magnetic resonance imaging (MRI) and Raman optical imaging which involves administering an MRI imaging contrast agent that a chemical structure having c...  
WO/2018/016611A1
Provided is a novel therapeutic agent for glaucoma, which has an sGC-activating activity. A therapeutic agent for glaucoma or an ocular hypotensive agent, which contains, as an active ingredient, a compound represented by formula (I-a) o...  
WO/2018/015677A1
The invention relates to the field of resolution of chiral compounds existing in the form of two optical antipodes (enantiomers), such as Baclofen. More particularly, the invention relates to the production of the pure enantiomer (R)(-) ...  
WO/2018/012459A1
An oxygen separation membrane which is configured of a porous material and a complex in the form of a liquid, said complex being internally contained in the porous material, and wherein: the complex contains a metal salen complex or a de...  
WO/2018/004945A1
A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):  
WO/2017/222043A1
The purpose of the present invention is to provide: a crystal of HMB amino acid salt, which is easy to handle and is highly soluble; and a production method of said crystal. According to the present invention, a crystal of HMB amino acid...  
WO/2017/222921A1
Substituted derivatives of 2-hydroxyisophthalic acid are provided, as well as new synthetic routes for making 2-hydroxyisophthalic acid and the substituted derivatives. Potential uses of the derivatives in a variety of applications are a...  
WO/2017/221079A1
The present invention relates to a mycotoxin adsorbant based on a betaine derivative and highly specific for type A and B trichothecenes, especially for vomitoxin (or deoxynivalenol) and T-2 toxin, and to a method for preparing said myco...  
WO/2017/220308A1
Process for making a powder or granule containing at least one chelating agent selected from alkali metal salts of methyl glycine diacetic acid (MGDA) and glutamic acid diacetate (GLDA) and iminodisuccinic acid (IDS), said process compri...  
WO/2017/216299A1
The object of the present invention are compounds comprising at least one donor group and at least one acceptor group, as described herein, which are characterized by a pronounced CT character. The invention also relates to the use there...  
WO/2017/209117A1
The present invention relates to a detergent composition for fibres which includes: component (A), namely C17-24 internal olefin sulfonates; component (B), namely a nonionic surfactant; and component (C), namely a metal ion chelating age...  
WO/2017/208258A1
The present invention discloses a novel process for the preparation of gadolinium complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9- triazaundecanedioic acid disodium of formula 1 and novel intermediates thereof.  
WO/2017/205588A1
This document relates to an aqueous composition comprising chlorambucil and human serum albumin, wherein the chlorambucil and the human serum albumin in the aqueous composition have a ratio by weight from about 1:10 to about 1:2000, wher...  
WO/2017/199513A1
The present invention addresses the problem of providing a liquid crystal composition which does not require an alignment treatment or an alignment film on the substrate, and solves this problem by providing a low molecular polar compoun...  
WO/2017/199514A1
The present invention addresses the problem of providing a liquid crystal display element that has a liquid crystal composition which does not require an alignment treatment or an alignment film on the substrate, and solves this problem ...  
WO/2017/199512A1
The present invention addresses the problem of providing a liquid crystal composition which does not require an alignment treatment or an alignment film on the substrate, and solves this problem by providing a low molecular polar compoun...  
WO/2017/199227A1
The present invention relates to a simple economical process for the preparation of 3,4- dihydroxy-2-methyl benzoic acid C1-4 alkyl ester and novel intermediates for use in the process.  
WO/2017/191453A1
A metal-EDTA compound/complex for combatting biofilms and/or treating wounds. The compound/complex comprises EDTA and from two to four metal ions. Of those two to four metal ions, at least two are different metal ions selected from Ag, A...  
WO/2017/189311A1
Glycan Composites and methods for rendering glycan composites for the treatment of photosynthetic organisms, including the steps of formulating branched glycan deglycosylates into coordination complex compositions resulting in water-born...  
WO/2017/183539A1
[Problem] To provide a compound that can be used on an industrial scale. [Solution] A compound represented by general formula (4) or a base adduct thereof. (In the formula, R3 and R4 independently represent a hydrogen atom or the like.)  
WO/2017/183734A1
Provided is an amino acid derivative prodrug represented by general formula (I-A) that is a prodrug form of an amino acid derivative which is a group 2 metabotropic glutamate receptor antagonist, or a pharmaceutically acceptable salt the...  
WO/2017/181118A1
The present invention provides methods for producing cannabinoid prodrugs. Also described are pharmaceutically acceptable compositions of the prodrugs and a system for the large-scale production of the prodrugs.  
WO/2017/176974A1
The present disclosure relates to a series of biodegradable amino-ester lipid-like nanoparticles. In some embodiments, the biodegradable amino-ester lipid-like nanoparticles are used in methods for the delivery of nucleic acids.  
WO/2017/173019A1
This invention relates to novel compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to a method of making the novel compositions of the invention comprising the rea...  
WO/2017/168313A1
The present invention provides an improved process for preparation of L-threo-(2S,3R)-3-(3.4- dihydroxyphenyl)serine (I) (Droxidopa) and its salts; comprising (a) reaction of the aldehyde compound (III) (as described herein) with Metal c...  
WO/2017/164363A1
The present invention provides a liquid softener composition, which is capable of controlling generation of a sulfur-like odor while continuously realizing the fragrance intended in design and which has excellent storage stability at a l...  
WO/2017/161095A1
Provided herein are rigid macrocycles comprising a first redox-active subunit and a second redox-active subunit, wherein the first redox-active unit and the second redox-active unit are different subunits. Also provided herein are method...  
WO/2017/160784A1
The present invention provides energy-curable compositions comprising aminoacrylates produced by the Michael addition reaction of any blend of highly alkoxylated monomers with any blend of mono- and/or bireactive amines. Suitable highly ...  
WO/2017/160709A1
A compound that is selected from the group consisting of 3-(3,4-dichloroanilino)-3-oxopropanoic acid (hereinafter "DCOPA"); N-methyl-DCOPA; N,2-dimethyl-DCOPA; 2-methyl-DCOPA; isobutyl-DCOPA; N-methyl-isobutyl DCOPA; 3-(3,4-bibromoanilin...  
WO/2017/156164A1
The present invention concerns compounds and their use to treat cardiovascular disease, renal disease, thrombic disease, stroke, metabolic syndrome, cell proliferation, and ischemic cardiovascular disorders. Compounds of the present inve...  
WO/2017/154738A1
The present invention addresses the problem of providing a novel method for producing an optically active amine compound that is useful as an intermediate for a medicine, an agrochemical, an electronic material and the like. A method for...  

Matches 1 - 50 out of 13,945