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Matches 1 - 50 out of 15,618

Document Document Title
WO/2018/177488A1
Acrylamide photoinitiators are provided, in which a photoinitiator moiety and an acrylamide are incorporated into the photoinitiator structure.  
WO/2018/171575A1
Substituted aromatic compounds of formula (I) shown below: (formula I) The definition of each variable in formula (I) appears in the Specification. Also disclosed is a pharmaceutical composition containing one of the substituted aromatic...  
WO/2018/175601A1
The present disclosure generally provides compounds useful for treating cancer. In some aspects, the disclosure provides platinum compounds that are chemically modified to have one or more moieties that include hydrophobic portions. In s...  
WO/2018/172783A1
There is described a method of reducing polymer tar build-up in the production of methyl methacrylate and/or methacrylic acid by the acetone cyanohydrin process. In the method a stabiliser is contacted with the amide stage reaction mediu...  
WO/2018/166505A1
Disclosed are a compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method therefor, and an application thereof in preventing or treating fatty liver or in preparing weight-reducing drugs.  
WO/2018/167801A1
The present invention disclosed a novel tricyclic compound of formula (I), process for the preparation and use thereof in the treatment of cancer. The present invention further relates to novel compound of formula (II) which is used as i...  
WO/2018/166504A1
Disclosed are a compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method therefor, the formula I, and an application thereof in preparing drugs for regulating blood lipids.  
WO/2018/159028A1
The present invention provides an industrially excellent production method by which N-benzyl-2-bromo-3-methoxypropionamide can be safely produced in high yield at lower cost. The production method of the present application comprises, in...  
WO/2018/153364A1
Disclosed are an osalmid crystal form II, a preparation method therefor, and applications thereof. An XRPD indicated by an 2θ angle, of the crystal form has characteristic peaks at the diffraction angels 7.527±0.2, 13.653±0.2, 14.644...  
WO/2018/156500A1
Methods of synthesizing polyfluorinated amino acid derivatives are disclosed, along with polyfluorinated amino acid derivatives produced from said methods, as well as compositions containing same. The synthesis methods utilize an oxazolo...  
WO/2018/146285A1
The present invention relates to a method for the production of organo-iodinated compounds, as well as the production intermediates thereof. More specifically, the present invention relates to a method for the production of organo-iodina...  
WO/2018/141276A1
Disclosed are a novel crystal form of a brivaracetam intermediate compound (I) and preparation method thereof, and a novel crystal form of brivaracetam and preparation method thereof, specifically a crystal form A of a compound I and a c...  
WO/2018/144385A1
A convenient method for converting oximes into enamides is disclosed. The process produces enamides without the concomitant production of a large volume of metallic waste (I). The enamides are useful precursors to amides and amines.  
WO/2018/144101A1
Described herein are labeling agents, specifically [11C]fluoroform, [11C]difluoromethane, [11C]fluoromethyl iodide, [11C]fluoromethyl bromide, [11C]fluoromethyl chloride, [11C]fluoromethyl trifluoromethansulfonate, [11C]difluoromethyl io...  
WO/2018/135574A1
A method for producing N-(α-hydroxyethyl)formamide which comprises reacting formamide with acetaldehyde in a solvent in the presence of a basic catalyst in a reaction vessel, precipitating the obtained N-(α-hydroxyethyl)formamide in th...  
WO/2018/132550A1
Provided herein are radiolabeled compounds useful for minimally invasive imaging techniques. An exemplary radiolabeled compound provided herein is useful as a radiotracer for position emission tomography imaging of voltage gated sodium c...  
WO/2018/117140A1
The purpose of the present invention is to provide L-alanyl-L-glutamine crystals having a low rough specific volume, and a method for producing same. This invention pertains to L-alanyl-L-glutamine crystals having a rough specific ratio ...  
WO/2018/107453A1
Provided in the present invention is a curing compound having good solvent solubility and being able to form a cured product having ultra-high heat resistance. The curing compound of the present invention is expressed by the following fo...  
WO/2018/105720A1
Provided is a production method for N–(α–hydroxyethyl) formamide, having a step (1) in which a basic catalyst stored in a catalyst supply device and formamide are mixed in a mixing tank; and a step (2) in which the formamide mixed w...  
WO/2018/105724A1
A method for purifying an N-(α-alkoxyethyl)formamide contained in a mixture thereof with a plurality of distillation columns, the plurality of distillation columns being arranged serially, the method including condensing a distillate fr...  
WO/2018/104228A1
The present invention generally relates to a process using a mechanochemical approach exploiting the mechanical milling of reactants for the manufacturing of acetyl Iopamidol and, more generally, of key intermediates of radiographic cont...  
WO/2018/099271A1
The prevent invention provides a method for preparing deuterated chemicals, and deuterated chemicals. The method comprises the step of: making halides undergo a deuteration reaction with a deuterium source under the catalytic action of a...  
WO/2018/095359A1
Disclosed is a tri-functional compound, a preparation method therefor and use thereof. The name of the compound is 1,3,5-tri(4-methylacrylamidophenyl)benzene, and the structural formula is as follows. The tri-functional compound, 1,3,5-t...  
WO/2018/090929A1
Provided is a method for biologically preparing (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine D-mandelate (I), comprising: (a) performing an asymmetric reduction reaction with a compound of formula (VI) as a substrate in the presence of...  
WO/2018/087019A1
The invention relates to a method for producing amide bonds, particularly peptide bonds, with the aid of new amide coupling reagents containing an anion of formula (I); the invention also relates to these new reagents and to the producti...  
WO/2018/086287A1
Provided is a method for preparing a chloramphenicol compound, comprising the following steps: adding a chloramphenicol intermediate to a buffer solution; and adding ketoreductase to the solution for performing asymmetric reduction on a ...  
WO/2018/084177A1
A method for producing N-vinylformamide through a vapor-phase thermal decomposition reaction using an evaporator (10) for evaporating a raw material, a thermal decomposition reactor (20) for thermally decomposing a raw material gas gener...  
WO/2018/074598A1
Disclosed are: an iron oxide which has the shape of a tube or a rod and contains at least one element selected from the group consisting of aluminum, zirconium, ruthenium, titanium and hafnium so that the elemental ratio of the element i...  
WO/2018/068937A1
The invention relates to a method for producing carboxamides of formula (1) by reacting at least one alkyl phenyl carboxylic acid of formula (2) with at least one secondary amine of formula (3), where R1 represents an alkyl group having ...  
WO/2018/062729A1
The present invention relates to a pseudo-ceramide compound and a preparation method therefor. According to the present invention, the pseudo-ceramide compound has a molecular structure and a function similar to those of a natural cerami...  
WO/2018/062422A1
[Problem] To provide a novel diamine for imparting a thin film that has not only exceptional flexibility and transparency, but also low retardation. [Solution] Provided are: a diamine characterized by being represented by formula (1-1); ...  
WO/2018/051042A1
The invention relates to a method for the industrial synthesis of the compound of formula (I).  
WO/2018/045505A1
Provided are new crystalline forms A, B, C, D, and E of sacubitril sodium salt and a method for preparation thereof, pharmaceutical compositions thereof, and application thereof in preparing drugs for enkephalinase-related diseases.  
WO/2018/041615A1
Processes and systems for producing N-vinyl carboxylic acid amides are provided herein. According to some aspects of the present invention, a process for producing an N-vinyl carboxylic acid amide is described that eliminates interim sol...  
WO/2018/038436A1
The present invention provides a novel diamine compound capable of producing a polymer which exhibits greatly enhanced mechanical properties and heat resistance while maintaining transparency. A film including a polymer produced using th...  
WO/2018/033866A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate comp...  
WO/2018/030533A1
Provided are: a method for producing an N-(α-alkoxyethyl)formamide, which comprises mixing N-(α-hydroxyethyl)formamide with an alcohol and then adding an acid catalyst within 3 hours after the starting of the mixing, and which makes it...  
WO/2018/025429A1
Provided is a simple method for producing perfluoroalkyl compounds that serve as important intermediates for organic electronic materials, pharmaceuticals, agricultural chemicals, polymer functional materials, etc., the method involving ...  
WO/2018/026703A1
Provided herein are Alanyl-Glutamine (Ala-GIn) formulations for use in treating and preventing side effects associated with cancer treatment. Also provided herein are methods of using the formulations provided herein to treat or prevent ...  
WO/2018/018863A1
Disclosed are a mild and efficient preparation method for an α-acyloxy alkenyl amide compound and a use thereof in the synthesis of an amide and a polypeptide. The α-acyloxy alkenyl amide compound is obtained by an addition reaction of...  
WO/2018/018851A1
A preparation method for oseltamivir carboxylic acid hydrochloride comprises the following steps: a, introducing protective groups A to amidos of oseltamivir phosphate 1, so as to obtain a compound 2; b, hydrolyzing ester groups on the c...  
WO/2018/018113A1
The present invention relates to methods for producing spilanthol and spilanthol analogues, as well as the resultant spilanthol 1 and analogues thereof. Spilanthol and spilanthol analogues according to the present invention exhibit high ...  
WO/2018/016376A1
The present disclosure provides a reaction of a chlorine-containing compound with use of a flow reactor that has few limits on a solvent to be used therein. According to the present disclosure, a chlorine-containing compound and a reacti...  
WO/2018/011696A1
The present invention is directed to reaction mixtures comprising a water-surfactant mixture, wherein the catalyst comprises a compound with solubilizing groups. This technology improves the solubility of the reaction components in the w...  
WO/2018/010932A1
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...  
WO/2018/001680A1
The invention relates to a method in which an amino acid is, in the presence of an amine, reacted with an acyl group donor to obtain an N-acyl amino acid.  
WO/2018/001148A1
Provided is a method for preparing a pregabalin intermediate 3-isobutylglutaric acid monoamide. The method comprises: 1) adding 3-isobutylglutaric acid and urea into a first organic solvent; 2) keeping warm and refluxing when heated to 1...  
WO/2017/213137A1
Provided is a novel agricultural/horticultural chemical for controlling pests in crop production such as agriculture and horticulture. An anilide compound or thioamide compound of a specific structure having a substituent shown by the fo...  
WO/2017/211145A1
The present invention discloses a micro/nanomaterial, a product thereof with a surface covalently modified with a hydrophilic material, and a manufacturing method. The surface of the micro/nanomaterial comprises a carboxyl group or poten...  
WO/2017/204144A1
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal o...  

Matches 1 - 50 out of 15,618