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Matches 1 - 50 out of 15,501

Document Document Title
WO/2018/011696A1
The present invention is directed to reaction mixtures comprising a water-surfactant mixture, wherein the catalyst comprises a compound with solubilizing groups. This technology improves the solubility of the reaction components in the w...  
WO/2018/010932A1
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...  
WO/2018/001680A1
The invention relates to a method in which an amino acid is, in the presence of an amine, reacted with an acyl group donor to obtain an N-acyl amino acid.  
WO/2018/001148A1
Provided is a method for preparing a pregabalin intermediate 3-isobutylglutaric acid monoamide. The method comprises: 1) adding 3-isobutylglutaric acid and urea into a first organic solvent; 2) keeping warm and refluxing when heated to 1...  
WO/2017/213137A1
Provided is a novel agricultural/horticultural chemical for controlling pests in crop production such as agriculture and horticulture. An anilide compound or thioamide compound of a specific structure having a substituent shown by the fo...  
WO/2017/211145A1
The present invention discloses a micro/nanomaterial, a product thereof with a surface covalently modified with a hydrophilic material, and a manufacturing method. The surface of the micro/nanomaterial comprises a carboxyl group or poten...  
WO/2017/204144A1
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal o...  
WO/2017/191332A3
A process of forming compounds of formula (I) comprising the steps of addition of an amino compound H2NR to a compound of formula (II) followed by cyclization, isomerization and hydrolysis.  
WO/2017/191620A1
The present invention provides a process for the preparation of a salt of sacubitril. Specifically, the present invention provides a process for the preparation of a sodium salt of sacubitril. The present invention further provides a cry...  
WO/2017/190299A1
A method for recovering a DMAC or DMF waste liquid using seven-tower five-effect rectification. The waste liquid comprising DMAC or DMF is entered into a DMAC or DMF finished product tank after being successively processed via a preheate...  
WO/2017/186685A1
A method for preparing an aqueous polyacrylamide solution is disclosed. The method comprises: hydrating acrylonitrile in water in presence of a biocatalyst capable of converting acrylonitrile to acrylamide so as to obtain an acrylamide s...  
WO/2017/186779A1
The present invention thus relates to amide derivatives of polysubstituted quinic acids (abbreviated to "QPS"), of general formula (IA): (IA), in which - R1A and R2A are, independently of one another: H, with the proviso that R1A and R2A...  
WO/2017/185261A1
The present invention relates to the technical field of medicine, and provides mosapride active metabolites (R)-N-[2-hydroxy-3-(4-fluorobenzyl)amino]propyl-5-chloro-4-a mino-2-ethoxy benzamide (levo isomer) and (S)-N-[2-hydroxy-3-(4-fluo...  
WO/2017/179976A1
The invention relates to improved means and methods for N- dealkylation of alkylated amines. Provided is a method for the catalytic N- dealkylation of an N-alkylated amine substrate, comprising incubating said amine substrate in a suitab...  
WO/2017/177979A1
Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being desc...  
WO/2017/177781A1
The present invention relates to AHU377 crystal forms, and a preparation method therefor and the use thereof. Provided are AHU377 crystal forms III and IV, and the crystal forms III and IV have a good stability, a low hygroscopicity, a h...  
WO/2017/174616A1
The present invention relates to a new process for synthesizing an amido alkyl betaine starting from a linear alcohol having from 8 to 22 carbon atoms, to an amido alkyl betaine prepared by the process with increased viscosity in water, ...  
WO/2017/166188A1
A latent curing accelerator composition, comprising: an aromatic polyisocyanate, a chain extender, a chain stopper, and a non-latent curing accelerator having at least one tertiary amine group. In particular, a one-part epoxy-thiol adhes...  
WO/2017/166914A1
The present invention relates to a preparation method of a three-arm atom transfer radical polymerization (ATRP) initiator with a planar-conjugated structure. First, 1,3,5-tris(4-aminophenyl)benzene is reacted in a nucleophilic substitut...  
WO/2017/156687A1
A method for preparing an amide compound, comprising the following steps: add an amine compound, a hydrazide compound, potassium persulfate and copper phthalocyanine to a solvent, and react at 95 to 100°C to obtain the amide compound. T...  
WO/2017/157932A1
The invention relates to a new and efficient process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or ...  
WO/2017/154024A1
Provided herein are processes for manufacture of acetylated amines including paracetamol.  
WO/2017/154024A4
Provided herein are processes for manufacture of acetylated amines including paracetamol.  
WO/2017/153161A1
The invention relates to a method for synthesizing aqueous N-acyl amino acid solutions. Said method does not require any solid to be isolated and yields solutions that have a low impurity content. The invention further relates to the cor...  
WO/2017/148357A1
The present invention relates to a sacubitril intermediate and a preparation method thereof. The sacubitril intermediate can be prepared by subjecting a compound to a deprotection reaction. The intermediate can be used as a raw material ...  
WO/2017/147646A1
The invention relates to a dual emission fluorescent compound comprising a chromophore suitable for exhibiting an emission at a first wavelength from an excited state; wherein the compound further comprises one or more groups suitable fo...  
WO/2017/145569A1
Provided is a method for producing an N-vinyl carboxylic acid amide, the method focusing on unsaturated aldehydes that are contained as impurities generated during a reaction. The method for producing an N-vinyl carboxylic acid amide is ...  
WO/2017/141512A1
Provided is a catalyst represented by general formula (1), where R1-R16 in the general formula (1) individually represent a hydrogen atom or a substituent independently of each other.  
WO/2017/141193A1
The present invention provides processes for the preparation of sacubitril or salts thereof. The present invention further provides intermediates of Formula IV, V and VI and their use for the preparation of sacubitril or salts thereof.  
WO/2017/128860A1
The present invention discloses a carboxamide or amine compound, a preparation method thereof, and application thereof as a stable and efficient antioxidative stabilizer, and relates to the technical field of novel antioxidative stabiliz...  
WO/2017/129272A1
The disclosure generally provides methods for preparing compositions comprising alkanolamine alkylamides and polyols. This disclosure further relates to methods for preparing compositions comprising alkanolamine alkylamides and polyols t...  
WO/2017/125031A1
Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for prepar...  
WO/2017/122730A1
[Problem] To provide a novel diamine that produces a film having excellent flexibility and transparency and also having low retardation characteristics. [Solution] Disclosed are: a diamine characterized by being represented by formula (1...  
WO/2017/122649A1
Provided is a fluorine atom-containing compound represented by formula (1) below (In the formula, Z represents a predetermined divalent group, each Ar independently represents a predetermined aromatic ring-containing group, and each ArF ...  
WO/2017/113502A1
The present invention relates to a method for preparing a long-chain compound, comprising the following steps: 1) performing a condensation reaction of H-R2 and R5N-Glu(OR4)-OR3, wherein R3 is a carboxyl protecting group, R4 is a carboxy...  
WO/2017/116188A2
The present invention relates to a method capable of selectively synthesizing cationic lipids by adjusting the introduction rate of a fatty acid group with respect to an oligoalkyleneamine by the change of a reaction condition.  
WO/2017/116188A3
The present invention relates to a method capable of selectively synthesizing cationic lipids by adjusting the introduction rate of a fatty acid group with respect to an oligoalkyleneamine by the change of a reaction condition.  
WO/2017/107789A1
Disclosed are a compound having a chiral spirobiindane skeleton and a preparation method therefor. The compound having a chiral condensed ring spirobiindane skeleton of the present invention is represented by formula I or I'. The prepara...  
WO/2017/108960A1
The present invention relates to a novel method for preparing monomethyl fumarate, which can preferably be used in the treatment and/or prevention of systemic diseases, autoimmune diseases, inflammatory diseases such as multiple sclerosi...  
WO/2017/104838A1
A method for producing an aromatic amide derivative represented by general formula (I), which comprises: a step a for obtaining an imide form compound represented by general formula (IV) by reacting an aniline derivative represented by g...  
WO/2017/102802A1
The present invention relates to a compound of formula (I) for its depigmenting, lightening and/or bleaching the skin in which R1 and R2 independently denote H, an alkyl radical, a radical S* denoting a monosaccharide sugar radical or a ...  
WO/2017/102659A1
The invention relates to a method for synthesising at least one nitrogen compound belonging to the family of the partially N-hydroxyethylated tertiary 1,6-hexanediamines of the following general formula (I) in which the groups R1, R2 and...  
WO/2017/097085A1
Disclosed is a preparation method for a eutectic hydrate crystal form II of AHU-377 and diovan trisodium salt, comprising: firstly, obtaining a clear solution of an AHU-377 and diovan trisodium salt compound, a solvent of the clear solut...  
WO/2017/097193A1
The present invention provides a method for refining a lisinopril hydride crude product by means of solvent crystallization. The method specifically comprises: adding ketones solvents into a crude product which contains lisinopril hydrid...  
WO/2017/098533A2
The present invention relates to a process for preparation of lisdexamphetamine and its pharmaceutically acceptable salts via a novel aziridine intermediate of Formula IV.  
WO/2017/097187A1
The present invention relates to a compound, a preparation method therefor, applications thereof, a corresponding targeted drug delivery system, and chemotherapy drugs. The compound is a novel compound for treating a small cell lung canc...  
WO/2017/098533A3
The present invention relates to a process for preparation of lisdexamphetamine and its pharmaceutically acceptable salts via a novel aziridine intermediate of Formula IV.  
WO/2017/096772A1
Disclosed is a method for preparing an anti-heart-failure medicine LCZ696. The preparing method comprises the following steps (formula (I)): in an organic solvent, a sacubitril dicyclohexylamine salt reacts with valsartan under the effec...  
WO/2017/092034A1
Provided is a method for synthesizing a gasoline additive alkyl formamide phenyl ether, comprising: (a) adding hydroxybenzoic acid, alkali, alkylation reagent, and solvent to a four-necked flask; the molar ratio of said hydroxybenzoic ac...  
WO/2017/089809A1
A tetracycline salt comprising a tetracycline and an organic acid wherein the organic acid is oxalic acid or maleic acid is provided. The tetracycline is preferably doxycycline, minocycline, sancycline, lymecycline, tetracycline or demec...  

Matches 1 - 50 out of 15,501