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Matches 1 - 50 out of 15,548

Document Document Title
WO/2018/068937A1
The invention relates to a method for producing carboxamides of formula (1) by reacting at least one alkyl phenyl carboxylic acid of formula (2) with at least one secondary amine of formula (3), where R1 represents an alkyl group having ...  
WO/2018/062729A1
The present invention relates to a pseudo-ceramide compound and a preparation method therefor. According to the present invention, the pseudo-ceramide compound has a molecular structure and a function similar to those of a natural cerami...  
WO/2018/062422A1
[Problem] To provide a novel diamine for imparting a thin film that has not only exceptional flexibility and transparency, but also low retardation. [Solution] Provided are: a diamine characterized by being represented by formula (1-1); ...  
WO/2018/051042A1
The invention relates to a method for the industrial synthesis of the compound of formula (I).  
WO/2018/045505A1
Provided are new crystalline forms A, B, C, D, and E of sacubitril sodium salt and a method for preparation thereof, pharmaceutical compositions thereof, and application thereof in preparing drugs for enkephalinase-related diseases.  
WO/2018/041615A1
Processes and systems for producing N-vinyl carboxylic acid amides are provided herein. According to some aspects of the present invention, a process for producing an N-vinyl carboxylic acid amide is described that eliminates interim sol...  
WO/2018/038436A1
The present invention provides a novel diamine compound capable of producing a polymer which exhibits greatly enhanced mechanical properties and heat resistance while maintaining transparency. A film including a polymer produced using th...  
WO/2018/033866A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate comp...  
WO/2018/030533A1
Provided are: a method for producing an N-(α-alkoxyethyl)formamide, which comprises mixing N-(α-hydroxyethyl)formamide with an alcohol and then adding an acid catalyst within 3 hours after the starting of the mixing, and which makes it...  
WO/2018/025429A1
Provided is a simple method for producing perfluoroalkyl compounds that serve as important intermediates for organic electronic materials, pharmaceuticals, agricultural chemicals, polymer functional materials, etc., the method involving ...  
WO/2018/026703A1
Provided herein are Alanyl-Glutamine (Ala-GIn) formulations for use in treating and preventing side effects associated with cancer treatment. Also provided herein are methods of using the formulations provided herein to treat or prevent ...  
WO/2018/018863A1
Disclosed are a mild and efficient preparation method for an α-acyloxy alkenyl amide compound and a use thereof in the synthesis of an amide and a polypeptide. The α-acyloxy alkenyl amide compound is obtained by an addition reaction of...  
WO/2018/018851A1
A preparation method for oseltamivir carboxylic acid hydrochloride comprises the following steps: a, introducing protective groups A to amidos of oseltamivir phosphate 1, so as to obtain a compound 2; b, hydrolyzing ester groups on the c...  
WO/2018/018113A1
The present invention relates to methods for producing spilanthol and spilanthol analogues, as well as the resultant spilanthol 1 and analogues thereof. Spilanthol and spilanthol analogues according to the present invention exhibit high ...  
WO/2018/016376A1
The present disclosure provides a reaction of a chlorine-containing compound with use of a flow reactor that has few limits on a solvent to be used therein. According to the present disclosure, a chlorine-containing compound and a reacti...  
WO/2018/011696A1
The present invention is directed to reaction mixtures comprising a water-surfactant mixture, wherein the catalyst comprises a compound with solubilizing groups. This technology improves the solubility of the reaction components in the w...  
WO/2018/010932A1
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...  
WO/2018/001680A1
The invention relates to a method in which an amino acid is, in the presence of an amine, reacted with an acyl group donor to obtain an N-acyl amino acid.  
WO/2018/001148A1
Provided is a method for preparing a pregabalin intermediate 3-isobutylglutaric acid monoamide. The method comprises: 1) adding 3-isobutylglutaric acid and urea into a first organic solvent; 2) keeping warm and refluxing when heated to 1...  
WO/2017/213137A1
Provided is a novel agricultural/horticultural chemical for controlling pests in crop production such as agriculture and horticulture. An anilide compound or thioamide compound of a specific structure having a substituent shown by the fo...  
WO/2017/211145A1
The present invention discloses a micro/nanomaterial, a product thereof with a surface covalently modified with a hydrophilic material, and a manufacturing method. The surface of the micro/nanomaterial comprises a carboxyl group or poten...  
WO/2017/204144A1
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal o...  
WO/2017/191332A3
A process of forming compounds of formula (I) comprising the steps of addition of an amino compound H2NR to a compound of formula (II) followed by cyclization, isomerization and hydrolysis.  
WO/2017/191620A1
The present invention provides a process for the preparation of a salt of sacubitril. Specifically, the present invention provides a process for the preparation of a sodium salt of sacubitril. The present invention further provides a cry...  
WO/2017/190299A1
A method for recovering a DMAC or DMF waste liquid using seven-tower five-effect rectification. The waste liquid comprising DMAC or DMF is entered into a DMAC or DMF finished product tank after being successively processed via a preheate...  
WO/2017/186685A1
A method for preparing an aqueous polyacrylamide solution is disclosed. The method comprises: hydrating acrylonitrile in water in presence of a biocatalyst capable of converting acrylonitrile to acrylamide so as to obtain an acrylamide s...  
WO/2017/186779A1
The present invention thus relates to amide derivatives of polysubstituted quinic acids (abbreviated to "QPS"), of general formula (IA): (IA), in which - R1A and R2A are, independently of one another: H, with the proviso that R1A and R2A...  
WO/2017/185261A1
The present invention relates to the technical field of medicine, and provides mosapride active metabolites (R)-N-[2-hydroxy-3-(4-fluorobenzyl)amino]propyl-5-chloro-4-a mino-2-ethoxy benzamide (levo isomer) and (S)-N-[2-hydroxy-3-(4-fluo...  
WO/2017/179976A1
The invention relates to improved means and methods for N- dealkylation of alkylated amines. Provided is a method for the catalytic N- dealkylation of an N-alkylated amine substrate, comprising incubating said amine substrate in a suitab...  
WO/2017/177979A1
Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being desc...  
WO/2017/177781A1
The present invention relates to AHU377 crystal forms, and a preparation method therefor and the use thereof. Provided are AHU377 crystal forms III and IV, and the crystal forms III and IV have a good stability, a low hygroscopicity, a h...  
WO/2017/174616A1
The present invention relates to a new process for synthesizing an amido alkyl betaine starting from a linear alcohol having from 8 to 22 carbon atoms, to an amido alkyl betaine prepared by the process with increased viscosity in water, ...  
WO/2017/166188A1
A latent curing accelerator composition, comprising: an aromatic polyisocyanate, a chain extender, a chain stopper, and a non-latent curing accelerator having at least one tertiary amine group. In particular, a one-part epoxy-thiol adhes...  
WO/2017/166914A1
The present invention relates to a preparation method of a three-arm atom transfer radical polymerization (ATRP) initiator with a planar-conjugated structure. First, 1,3,5-tris(4-aminophenyl)benzene is reacted in a nucleophilic substitut...  
WO/2017/156687A1
A method for preparing an amide compound, comprising the following steps: add an amine compound, a hydrazide compound, potassium persulfate and copper phthalocyanine to a solvent, and react at 95 to 100°C to obtain the amide compound. T...  
WO/2017/157932A1
The invention relates to a new and efficient process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or ...  
WO/2017/154024A1
Provided herein are processes for manufacture of acetylated amines including paracetamol.  
WO/2017/154024A4
Provided herein are processes for manufacture of acetylated amines including paracetamol.  
WO/2017/153161A1
The invention relates to a method for synthesizing aqueous N-acyl amino acid solutions. Said method does not require any solid to be isolated and yields solutions that have a low impurity content. The invention further relates to the cor...  
WO/2017/148357A1
The present invention relates to a sacubitril intermediate and a preparation method thereof. The sacubitril intermediate can be prepared by subjecting a compound to a deprotection reaction. The intermediate can be used as a raw material ...  
WO/2017/147646A1
The invention relates to a dual emission fluorescent compound comprising a chromophore suitable for exhibiting an emission at a first wavelength from an excited state; wherein the compound further comprises one or more groups suitable fo...  
WO/2017/145569A1
Provided is a method for producing an N-vinyl carboxylic acid amide, the method focusing on unsaturated aldehydes that are contained as impurities generated during a reaction. The method for producing an N-vinyl carboxylic acid amide is ...  
WO/2017/141512A1
Provided is a catalyst represented by general formula (1), where R1-R16 in the general formula (1) individually represent a hydrogen atom or a substituent independently of each other.  
WO/2017/141193A1
The present invention provides processes for the preparation of sacubitril or salts thereof. The present invention further provides intermediates of Formula IV, V and VI and their use for the preparation of sacubitril or salts thereof.  
WO/2017/128860A1
The present invention discloses a carboxamide or amine compound, a preparation method thereof, and application thereof as a stable and efficient antioxidative stabilizer, and relates to the technical field of novel antioxidative stabiliz...  
WO/2017/129272A1
The disclosure generally provides methods for preparing compositions comprising alkanolamine alkylamides and polyols. This disclosure further relates to methods for preparing compositions comprising alkanolamine alkylamides and polyols t...  
WO/2017/125031A1
Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for prepar...  
WO/2017/122730A1
[Problem] To provide a novel diamine that produces a film having excellent flexibility and transparency and also having low retardation characteristics. [Solution] Disclosed are: a diamine characterized by being represented by formula (1...  
WO/2017/122649A1
Provided is a fluorine atom-containing compound represented by formula (1) below (In the formula, Z represents a predetermined divalent group, each Ar independently represents a predetermined aromatic ring-containing group, and each ArF ...  
WO/2017/113502A1
The present invention relates to a method for preparing a long-chain compound, comprising the following steps: 1) performing a condensation reaction of H-R2 and R5N-Glu(OR4)-OR3, wherein R3 is a carboxyl protecting group, R4 is a carboxy...  

Matches 1 - 50 out of 15,548