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Matches 751 - 800 out of 7,335

Document Document Title
WO/2005/000233A2
The present invention is directed to compounds having the structure (I) wherein R1, R2, R3, R4, R5 and m are as defined herein. The compounds of this invention are novel therapeutic agents for the treatment of cancer, metabolic diseases ...  
WO/2004/113273A1
Compounds of formula (I), wherein A0, A1, and A2 are each independently of the others a bond or a Cl-C6alkylene bridge; A3 is a Cl-C6alkylene bridge which is unsubstituted or substituted by from one to six identical or different substitu...  
WO/2004/110977A1
A process for producing an optically active, 1-alkyl-substituted 2,2,2-trifluoroethylamine represented by the formula [3] (wherein R represents C1-6 alkyl and * indicates asymmetric carbon) or a salt of the compound. These compounds are ...  
WO2004069900A3
Novel monoamidine, monoamidoxime and bisamidine curatives, co-curatives and cure accelerators are provided for use with perfluoroelastomeric compositions as well as novel synthesis methods for making monoamidine- and monoamidoxime-based ...  
WO/2004/108857A1
An organic electroluminescent device, which has a pair of electrodes and at least one organic layer including a luminescent layer between the pair of electrodes, wherein at least one layer between the pair of electrodes comprises at leas...  
WO/2004/103941A2
This invention provides estrogen receptor modulators having the structure (I) where R1-R5 are as defined in the specification; or a pharmaceutically acceptable salt thereof.  
WO/2004/101496A1
The invention relates to a method of creating a carbon-heteroatom bond and, preferably, a carbon-nitrogen bond, by reacting a leaving group-bearing unsaturated compound and a nucleophilic compound. In particular, the invention relates to...  
WO/2004/099122A2
This invention provides estrogen receptor modulators having the structure formula (I): wherein R1 to R6 and R8 are as defined in the specification; or a pharmaceutically acceptable salt thereof.  
WO/2004/098582A2
The present invention pertains to certain ketones and reduced ketones and derivatives thereof which, inter alia, inhibit osteoclast survival, formation, and/or activity; and/or inhibit bone resorption, and more particularly to compounds ...  
WO/2004/096755A1
A platinum complex represented by the following formula (1) or (2): wherein the ring A, ring B, ring C, ring D and ring G independently represent an aromatic ring optionally having a substituent or an aromatic heteroring optionally havin...  
WO2004080377A3
This invention relates to compounds of the general formula (I) useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.  
WO/2004/093207A2
The invention relates to novel mixtures consisting of at least two substances, one substance being used as a matrix material and the other as a material which is capable of emission and contains at least one element having an atomic numb...  
WO2004071442A3
The present invention relates to bicyclic derivatives, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of d...  
WO2004010512A3
Novel heterodiamondoids are disclosed. These heterodiamondoids are diamondoids that include heteroatoms in the diamond lattice structure. The heteroatoms may be either electron donating, such that an n-type heterodiamondoid is created, o...  
WO2004071401A3
A compound having the following formula (I): wherein R<1> is lower alkyl optionally substituted with one or more suitable substituent(s); aryl optionally substituted with one or more suitable substituent(s); or fused ring, R<2> is acylam...  
WO/2004/087641A1
A compound represented by the general formula (I), a salt thereof, or a solvate of either. (I) (In the formula, R1 means hydrogen, optionally substituted aryl, optionally substituted, (un) saturated, 5- to 7-membered, heterocyclic group,...  
WO2004065302A3
This invention relates to a novel crystal form of the 1:1 manganese (III) complex of N,N',N"tris[salicylideneaminoethyl]amine, a process for its preparation and the use thereof.  
WO2004058683A3
Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein X, ...  
WO/2004/080947A1
A compound represented by the following general formula (I), its salt, its solvate or its N-oxide or prodrugs thereof: (I) wherein R1 and R2 represent each an optionally substituted cyclic group, etc.; W is a spacer having from 1 to 6 ca...  
WO2004043884A3
Novel acylating agents useful for preparing activated nucleophiles such as terminally activated polymers are disclosed. In preferred aspects, the acylating agents are formula (I) and formula (II) and they used to prepare activated polyme...  
WO/2004/080377A2
This invention relates to compounds of the general formula (I) useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.  
WO2003105751A3
The present invention relates to a novel curcumin derivative and a pharmaceutical composition, in particular to a novel curcumin derivative with anti-angiogenic activity and a pharmaceutical composition for treating or preventing a disea...  
WO2003091207A3
This invention provides a method of preparing amine stereoisomers, which comprises stereoselectively reducing a sulfinylimine that bears on the sulfmyl group a residue of an alcohol, thiol or amine, or reacting a sulfmylimine stereoisome...  
WO/2004/078702A1
The invention relates to a process for the preparation of an &agr -amino carbonyl compound by reacting an imine starting material with a suitable electrophile in the presence of a base. This process has the advantage that the imine start...  
WO2004053458A3
A process is described for producing one or more substituted iminoamines, in particular beta-­unsaturated beta-iminoamines, in a single reaction comprising reacting one or more primary amines, alkynes, and isonitriles in the presence of...  
WO/2004/078924A2
The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding...  
WO2004052847A3
The present invention relates to methods of treating pathological disorders susceptible to steroid hormone nuclear receptor modulation comprising administering to a patient in need thereof an effective amount of a compound of the formula...  
WO2003079984A3
The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms...  
WO/2004/075885A1
The invention relates to novel isotetracenone derivatives, medicaments which contain said derivatives or the salts thereof and the use of the isotetracenone derivatives in the treatment of diseases, especially helicobacter pylori infecti...  
WO/2004/074242A2
Compounds of the formula (I) or (II) wherein R1 is C1-C10haloalkylsulfonyl, halobenzenesulfonyl, C2-C10haloalkanoyl, halobenzoyl; R2 is halogen or C1-C10haloalkyl; Arl is phenyl, biphenylyl, fluorenyl, naphthyl, anthracyl, phenanthryl, o...  
WO/2004/074236A1
A novel imino compound is synthesized by mixing and reacting ascochlorin, its analog or its derivative with a compound having a primary amino group in the presence/absence of a basic catalyst. The novel imino compound thus synthesized is...  
WO/2004/071442A2
The present invention relates to bicyclic derivatives, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of d...  
WO/2004/071401A2
A compound having the following formula (I): wherein R1 is lower alkyl optionally substituted with one or more suitable substituent(s); aryl optionally substituted with one or more suitable substituent(s); or fused ring, R2 is acylamino ...  
WO/2004/069900A2
Novel monoamidine, monoamidoxime and bisamidine curatives, co-curatives and cure accelerators are provided for use with perfluoroelastomeric compositions as well as novel synthesis methods for making monoamidine- and monoamidoxime-based ...  
WO/2004/067497A1
The invention relates to a process for treating an organic solution comprising cyclohexanone oxime, cyclohexanone and an organic solvent, said process comprising distilling the organic solution such as to obtain (i) a first product compr...  
WO2004056762A3
The invention provides novel compounds according to formula (I) relates to compounds with the general formula (I), said compounds being useful, e.g. in the treatment of inflammatory diseases.  
WO/2004/065302A2
This invention relates to a novel crystal form of the 1:1 manganese (III) complex of N,N',N'tris[salicylideneaminoethyl]amine, a process for its preparation and the use thereof.  
WO/2004/063148A1
The present invention relates to a compound of the formula ((I): in which: n is an integer chosen from 1, 2 and 3; Y represents O; N-OR9, in which R9 represents H or a saturated hydrocarbon-based aliphatic group; CR10R11, in which R10 an...  
WO/2004/062601A2
Antibacterial compounds of formula (I) are provided: As well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infectio...  
WO2004035551A3
The present invention is directed to novel fluorinated dye stabilizers having both high quenching efficiency and solubility in halogenated solvents. These dye stabilizers have shown a significantly effect on improving the dye fastness in...  
WO2003014296A3
Compounds containing a specific saturated or unsaturated branched chain terminal group; a polar leading group; and a long-chain aliphatic, non-cyclic, saturated or unsaturated, substituted or unsubstituted, hydrocarbon group linking them...  
WO/2004/058747A1
The present invention provides compounds capable of binding to an Fc receptor and modulating Fc receptor activity comprising a core lipophilic group in the form of an Aryl ring substituted with a group rich in p-electrons. The invention ...  
WO/2004/058683A2
Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein X, ...  
WO/2004/056762A2
The invention provides novel compounds according to formula (I) relates to compounds with the general formula (I), said compounds being useful, e.g. in the treatment of inflammatory diseases.  
WO2002034203A3
The present invention relates to novel antimycobacterial compounds and in particular to antimycobacterial compounds comprises of derivatives of phenyl 4-aminosalicylate. This invention further relates to methods for their preparation, to...  
WO/2004/054982A1
Disclosed are novel biphenylcarboxamides of formula (I), wherein R, Z, X, Y, m, n, and A have the meanings indicated in the description, several methods for producing said substances, the use thereof for controlling undesired microorgani...  
WO/2004/054954A1
A process for the purification of hydroxyaryl aldehydes and ketones comprising the following steps; 1) adding a mineral acid to a first composition comprising a hydroxyaryl aldehyde or a hydroxyaryl ketone; 2) washing the mixture obtaine...  
WO/2004/054961A1
A process for the preparation of substituted halogenated anilines from substituted halogenated 1-chlorobenzenes which comprisesa) reacting a substituted halogenated 1-chlorobenzene selectively with an imine in the presence of a transitio...  
WO/2004/053458A2
A process is described for producing one or more substituted iminoamines, in particular β-­unsaturated β-iminoamines, in a single reaction comprising reacting one or more primary amines, alkynes, and isonitriles in the presence of a t...  
WO/2004/052816A1
Compounds of formula (I), wherein A1 and A2 are each independently of the other a bond or a C1-C6alkylene bridge; A3 is a C1-C6alkylene bridge; X1 and X2 are each independently of the other fluorine, chlorine or bromine; Y is O, NR7, S, ...  

Matches 751 - 800 out of 7,335