Acyclic or Carbocyclic Compounds

Matches 1,351 - 1,400 out of 5,404	< 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 >

Document	Document Title
WO/1995/014688A1	DERIVATIVES OF 2,3,5,6-TETRAFLUOROBENZOIC ACID AND THEIR USE IN COMBATING PESTS The application relates to derivatives of 2,3,5,6-tetrafluorobenzoic acid of formula (I) wherein Y represents oxygen or sulphur and X represents the groups -O- N=CR1R2, -OR3, -OCHR4-CO-NR5R6 or -NR7R8 as well as a process for manufacturi...
WO/1995/013262A1	SUBSTITUTED PHENYL COMPOUNDS Compounds of formula (I) are described wherein R1 is hydrogen, -(lower alkyl)q(CO2R6 or OH), -CN, -C(R7)=NOR8, NO2, -O(lower alkyl)R9, -CC-R10, -CR11=C(R12)(R13), -C(=O)CH2C(=O)CO2H, -CO(R14), alkylthio, alkylsulphinyl, alkylsulphonyl, c...
WO/1995/012572A1	CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE The present invention provides a compound of formula (I) processes for the preparation of the compounds of the invention in addition to intermediates useful in these processes, a pharmaceutical composition, and a method of treating disor...
WO/1995/011226A1	SUBSTITUTED BENZENE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND BIOCIDAL COMPOSITION FOR CONTROL OF HARMFUL ORGANISMS CONTAINING THEM A substituted benzene derivative of formula (I), wherein A is an aryloxy group which may be substituted, an arylthio group which may be substituted or -ON=C(R1)R2, each of R1 and R2 which are independent of each other is an alkyl group w...
WO/1995/011231A1	AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS The current invention discloses useful pharmaceutical compositions containing amidino derivatives of formula (I) as nitric oxide synthase inhibitors.
WO/1995/011224A1	PROCESS FOR THE PREPARATION OF A SUBSTITUTED 2,5-DIAMINO-3-HYDROXYHEXANE Intermediates and processes are disclosed which are useful for the preparation of a substantially pure compound of formula (3), wherein R6 and R7 are each hydrogen or R6 and R7 are independently selected from (i), wherein Ra and Rb are i...
WO/1995/007269A1	POLAR-SUBSTITUTED HYDROCARBONS The invention relates to retroviral protease inhibitors of the general formula (I): W-(A)n-B-(A)m-V where W, A, B, A, V, n and m are as defined herein, including related prodrugs of general formula (I) comprising a solubilising group w...
WO/1995/007266A1	SUBSTITUTED LACTIC-ACID DERIVATIVES WITH AN ORGANIC N-GROUP IN THE BETA POSITION, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND ANTIDOTES The invention concerns substituted lactic-acid derivatives, containing an organic nitrogen group in the beta position, of general formula (I) in which the substituents R2 to R5 and X are as defined in the description and N is one of the ...
WO/1995/007291A1	KININOGEN INHIBITORS Kininogenase inhibiting peptides or peptide analogues with C-terminal residues related to agmatine or noragmatine.
WO/1995/006029A1	ENANTIOSELECTIVE SYNTHESIS OF ALPHA - ALKYLATED AMINO ACID DERIVATIVES BY PHASE - TRANSFER CATALYSIS Described are improved phase-transfer catalyzed processes for the higher-yield enantioselective synthesis of precursors for alpha-alkyl amino acids. The alpha-alkylation of N-blocked amino acid esters is carried out with alkyl chlorides ...
WO/1995/004552A2	RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE The invention concerns ligands, e.g. based on alkylene amine oxime particularly butylene amine oxime ring structures, and radiometal complexes thereof. The radiometal complexes are intrinsically capable of localising in tumours or hypoxi...
WO/1995/004027A1	AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS Compounds of formula (I) and salts thereof are useful for treating accumulation of calcium in brain cells, wherein X represents O, S, NH or a bond; p and q independently represent 0-4 such that the sum of p + q is at least 1; R1 and R2 e...
WO/1995/002576A1	PROCESS FOR THE PREPARATION OF N-CARBONYLARYLIMINES USEFUL FOR THE SYNTHESIS OF THERAPEUTICALLY ACTIVE TAXOIDS Process for the preparation of N-carbonylarylimines of general formula (I) by desulphonating a sulphone of general formula (II). The N-carbonylarylimines of general formula (I) are particularly useful for the preparation of therapeutical...
WO/1995/001957A1	OXIMATION PROCESS An improved process for oximation of carbonyl compounds, such as ketones and aldehydes by oximation with hydroxylamine including oximation processes carried out in the presence of a catalytic amount of a phase transfer catalyst comprised...
WO/1995/001329A1	PROCESS FOR PRODUCING alpha-HYDROXYIMINOPHENYLACETONITRILE A process for producing an alpha-hydroxyiminophenylacetonitrile represented by general formula [II], (wherein R1, R2, R3 and Z are each as defined in the specification) by reacting a crude nitrile containing a phenylacetonitrile represen...
WO/1995/001330A1	PROCESS FOR PRODUCING alpha-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE A process for producing an alpha-alkoxyiminophenylacetonitrile represented by general formula [III], (wherein R1, R2, R3 and Y are each as defined in the specification) by reacting an alkali metal salt of an alpha-hydroxyiminophenylaceto...
WO/1995/001327A1	THERMOTROPIC POLYUREAS AND USE THEREOF FOR DYEING AND MECHANICALLY AND THERMALLY STRENGTHENING POLYMERS Thermotropic polyreas produced by the (poly)addition of at least one polyisocyanate with at least one thermotropic aromatic diamine including imine junctions and having general formula H2N - R1 - N = CH - R2 - CH = N - R3 - NH2 wherein e...
WO/1995/001328A1	PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE A process for producing a carboxylic acid derivative represented by general formula [VIII], (wherein R1, R2, R3 and L are each as defined in the specification), which comprises reacting a benzyl halide with a cyano compound to give a phe...
WO/1994/027947A1	PHENYLCYCLOPROPANE COMPOUNDS AND THEIR USE AS cAMP AND TNF INHIBITORS This invention relates to substituted phenylcyclopropane derivatives, which carry various substituents on the cyclopropane ring, to processes for their preparation, to pharmaceutical compositions containing them, and to methods for their...
WO/1994/026696A1	HERBICIDAL CYCLOHEXANES Novel compounds of formula (1), and isomeric and/or tautomeric forms thereof, wherein A is C1-C3 alkylene or C3 alkenylene, each optionally substituted with 1 to 4 C1-C3 alkyl substituents; X is oxygen or a single bond; and R1 to R9 are ...
WO/1994/026697A1	OXIME COMPOUNDS USED AS CROSSLINKING AGENTS FOR COPOLYMERS A compound of formula (I), (II) or (III), in which R1 and R2 are independently a C1-C10 alkyl, alkoxy C1-C10, C5-C10 cycloalkyl or C5-C10 aryl radical which also contain 1 to 3 non-adjacent nitrogen, oxygen or sulphur atoms as heteroatom...
WO/1994/022812A1	IMINO-SUBSTITUTED PHENYLACETIC ACID AMIDES, THEIR PREPARATION AND FUNGICIDES CONTAINING THEM Described are compounds of the formula (I) in which Y is oxygen or an NR6 group; Z1 and Z2 are hydrogen, halogen, alkyl, alkenyl, alkinyl, alkoxy, alkenyloxy, haloalkyl, haloalkoxy, haloalkenyloxy, cyano or nitro; R1 is hydrogen, alkyl, ...
WO/1994/021599A1	NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY A compound with a platelet aggregation inhibitor activity, represented by the following general formula (I), and pharmacologically acceptable salt and solvate thereof. Examples of the compound are as in (II).
WO/1994/019331A1	ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES The invention concerns compounds of formula (I) in which the subscript and the substituents are defined as: n is 0 or 1 to 4; X is 0 or S; Y is a five-membered aromatic heterocycle ring; R1 is nitro, cyano, halogen, alkyl, haloalkyl, alk...
WO/1994/018174A1	SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES The present invention pertains to new substituted tetrahydropyridazine carboxamides of general formula (I), in which R1 stands for hydrogen or alkyl, R2 stands for alkyl carbonyl or alkoxy carbonyl or R1 and R2 together with the nitrogen...
WO/1994/015901A1	COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to membe...
WO/1994/015904A1	NOVEL PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PRODRUGS A tranexamic acid prodrug of general formula (II), is prepared by conversion of tranexamic acid in aqueous solution into a salt. An aromatic aldehyde of the formula Ar-CHO, lacking alpha-hydrogen atom is added to the solution and water i...
WO/1994/015902A1	COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to membe...
WO/1994/014755A1	AMINO ACID DERIVATIVE AND ANTI-ACTIVE-OXYGEN AGENT A novel anti-active-oxygen agent which inhibits the generation of active oxygen species, is highly safe, can be preparated at a rather low cost, and contains an amino acid derivative represented by general formula (I) or a salt thereof a...
WO/1994/014436A1	RETROVIRAL PROTEASE INHIBITING COMPOUNDS A retroviral protease inhibiting compound of formula (A) is disclosed.
WO/1994/014757A1	PROCESS AND INTERMEDIATE PRODUCTS FOR PREPARING HYDROXYLAMINE-ETHERS AND THEIR SALTS In order to prepare hydroxylamine-ethers having formula (I), in which X stands for NO2, CN, halogen, alkyl and halogen alkyl; Y stands for H, NO2, CN, halogen, alkyl and halogen alkyl; n equals 0 to 2 or 1 to 4 when Y and all X's stand f...
WO/1994/014742A1	TRI-SUBSTITUTED PHENYL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS Compounds of general formula (1) are described wherein Y is a halogen atom or a group -OR1, where R1 is an optionally substituted alkyl group; X is -O-, -S- or -N(R8)-, where R8 is a hydrogen atom or an alkyl group; R2 is an optionally s...
WO/1994/012277A1	OXYDATION CATALYSTS The invention concerns new oxidation catalysts, methods of producing them and their use. These catalysts consist of titanium silicalites crystallized in situ on to activated charcoal or metal oxides. The titanium silicalite content lies ...
WO/1994/011340A1	HYDRAZONE DERIVATIVE A compound representd by general formula (I), a salt thereof, and a pest control agent, wherein: X represents halogen, alkyl, alkoxy, cycloalkyloxy, alkylsulfonyloxy, alkylthio or alkylsulfonyl; R1 represents hydrogen or alkyl; R2 repres...
WO/1994/011334A1	SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES Compounds of general formula (I) in which the index and the constituents have the meanings below: n: 0, 1, 2, 3 or 4; X: CHOCH3, CHCH3 or NOCH3; Y: O or NH; R1: nitro, cyano, halogen, alkyl, alkyl halide, alkoxy, alkoxy halide, alkylthio...
WO/1994/010249A1	PIGMENT MANUFACTURING PROCESS A process of preparing a quinacridone of formula (VII), wherein X is methyl, chloro or fluoro, and n is 0, 1 or 2, which comprises : (a) treating a dialkylsuccinate of formula (II), wherein R is alkyl of 1 to 3 carbons atoms, with at lea...
WO/1994/008948A2	PROCESS FOR THE PREPARATION OF OXIME DERIVATIVES, CERTAIN INTERMEDIATES AND THE USE OF THE OXIME DERIVATIVES AS FUNGICIDES A process for the preparation of a compound of formula (I), wherein Y is O, S(O)n (wherein n is 0, 1 or 2) or NR5; W is CH3O.CH=C.CO2CH3, CH3O.CH=C.CONR6R7, CH3O.N=C.CO2CH3 or CH3O.N=C.CONR6R7; R1 is hydrogen, C1-4 alkyl, C1-4 haloalkyl ...
WO/1994/008949A2	METAL-OXIME CHELATES FOR USE AS RADIOPHARMACEUTICAL AGENTS The invention concerns novel metal chelating compounds, and radiometal, e.g. technetium-99m complexes thereof. The compounds can be used to radiolabel small biologically active species with minimal effect on their biodistribution and act...
WO/1994/008968A1	PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES A fungicidal compound having formula (I), wherein either: A is hydrogen, halogen, hydroxy, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl, C1-4 haloalkoxy, C1-4 alkylcarbonyl, C1-4 alkoxycarbonyl, phenoxy, nitro or cyano; and one of R1 and R2 i...
WO/1994/008943A1	2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT A 2-amino-1,3-propanediol compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, and an immunosuppressant containing the same as the active ingredient. In said formula R represents optionally substitut...
WO/1994/007847A1	METHOD FOR THE STEREOSELECTIVE PREPARATION OF A DERIVATIVE OF beta-PHENYLISOSERINE AND ITS USE IN THE PREPARATION OF TAXANE DERIVATIVES Method of stereoselective preparation of a derivative of beta-phenylisoserine of formula (I) by the action of an N-carbonylbenzylimine of formula (II) on an optically active amide of a protected hydroxyacetic acid of formula (III), follo...
WO/1994/006280A1	INHIBITORS OF METAZOAN PARASITE PROTEASES Compositions and methods for treating a patient infected with a metazoan parasite by inhibiting the enzymatic action of the metazoan parasite protease. These compositions and methods have particular utility in the treatment of schistosom...
WO/1994/005153A1	HERBICIDAL BENZENE COMPOUNDS Herbicidal compositions and method of use involving effective amounts of substituted benzene compounds to control the growth of undesired vegetation.
WO/1994/005626A1	AMIDE COMPOUND AND PLANT DISEASE CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT An amide compound represented by general formula (I) (wherein R1 represents lower alkyl, etc.; n represents an integer of 0 to 3; R2 represents lower alkyl; R3 and R4 may be the same or different from each other and each represents hydro...
WO/1994/004489A1	CYCLOHEXENONOXIME ETHERS, THEIR PREPARATION AND THEIR USE Cyclohexenonoxime ethers have formula (I) in which the substituents have the following meaning: R1 stands for alkyl; R2 for alkyl, halogen alkyl, alkenyl, halogen alkenyl, alkinyl or halogen alkinyl; -A1-O-N=CH-Ph or A2-W, in which A1 st...
WO/1994/003557A1	NOVEL NONLINEAR OPTICAL AMINOARYL HYDRAZONES AND NONLINEAR OPTICAL POLYMERS THEREOF The present invention relates to nonlinear optical materials comprising aminoaryl hydrazones and to nonlinear optical polymeric compositions containing recurring covalently bonded moieties derived from the aminoaryl hydrazones of the inv...
WO/1993/025588A1	DISPERSIONS OR SOLUTIONS CONTAINING HYDROXYLAMINE COMPOUNDS AS CROSS-LINKING AGENTS The invention concerns dispersions or solutions of a polymerizate, polycondensate or polyadduct formed by a radical reaction and including 0.001 to 20 % by wt. of aldehyde-CHO or ketone-CO-groups, the dispersion or solution containing as...
WO/1993/025519A1	COPOLYMERIZABLE OXIME ETHERS AND COPOLYMERS CONTAINING THEM The invention concerns copolymerizable oxime ethers of generale formula (I), in which A is a bivalent link group; R?1¿ is a hydrogen atom or a C¿1? to C¿4? alkyl group; and R?2¿ and R?3¿, independently of each other, may be a hydrog...
WO/1993/023357A1	STILBENE DERIVATIVES AS ANTICANCER AGENTS The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can be utilized in a method of treating such ...
WO/1993/022280A1	SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM Substituted cyclohexene-1,2-bicarboxylic acid derivatives (I), (R?1¿, R?2¿ = H, possibly substituted C¿1?-C¿6? alkyl, C¿3?-C¿6? alkenyl or C¿3?-C¿6? alkinyl, C¿3?-C¿8? cycloalkyl, possibly substituted phenyl or heterocyclyl) an...

Matches 1,351 - 1,400 out of 5,404	< 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 >