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Matches 101 - 150 out of 16,091

Document Document Title
WO/2023/013974A1
The present invention relates to a method for producing novel rucaparib which can achieve an excellent synthesis yield and reproducibility. More particularly, the present invention relates to: a novel production method for synthesizing r...  
WO/2023/015164A1
Described are the compounds, compositions and methods of treating a disease or disorder characterized by aberrant B-cell lymphoma 6 (BCL6) activity.  
WO/2023/008248A1
Provided is a reactive material that contains a compound represented by general formula (1) or (2). [Compound 1] (In formula (1), R1, R2, R3, and R4 each independently represent a hydrogen atom, a hydrocarbon group having 1-4 carbon at...  
WO/2023/003058A1
Provided in one embodiment is a method for preparing a phthalonitrile-based compound, comprising the steps of: (a) preparing a mixture comprising a phthalic acid-based compound and a nitrile-based compound; and (b) reacting the mixture, ...  
WO/2023/283831A1
Disclosed in the present invention is a compound having an inhibitory effect on a virus main protease (3CL protease, Mpro), which also has a significant inhibitory activity on the Mpros of SARS coronavirus (SARS-CoV) and novel coronaviru...  
WO/2023/284645A1
Disclosed in the present invention are an amide compound and a use thereof. The structure of the compound is as shown in general formula I; see the description for the definitions of substituents in the formula; and the use of the compou...  
WO/2023/287208A1
The purpose of the present invention is to provide a novel compound that efficiently absorbs light in the visible region as well as has favorable weather resistance, and provided are a compound, and a composition, a molded body, a dyed p...  
WO/2023/279836A1
Provided are an ionizable lipid compound of formula I for nucleic acid delivery and an LNP composition thereof, which can efficiently and stably deliver a biologically active substance to a target cell or an organ. The mRNA LNP prepared ...  
WO/2023/282556A1
The present specification discloses: a uricase-albumin conjugate and a method for producing same; and a uricase variant included in the uricase-albumin conjugate and a method for producing same. In particular, the present specification d...  
WO/2023/278688A1
Reaction pathways and conditions for the production of nitrogen-containing chelators, such as a glycine derivative, with reduction of ammonia byproducts. In particular, the present disclosure describes a process for the production of a n...  
WO/2023/277605A1
The present invention provides a novel compound for a capping layer and an organic light-emitting device containing same.  
WO/2023/273384A1
Provided in the present disclosure are a thermally activated delayed fluorescent material, an organic light-emitting device and a display apparatus. The energy level difference between a singlet energy level and a triplet energy level of...  
WO/2023/276954A1
Provided is a fluorine-containing ether compound that has excellent abrasion resistance even when the thickness thereof is low, and that can form a lubrication layer in which a reduction in film thickness caused by spin-off is unlikely t...  
WO/2022/267661A1
The present application belongs to the field of organic materials, and relates to an organic compound, and an electronic element and an electronic device using same. The organic compound has a structure as represented by formula 1, and t...  
WO/2022/255770A1
The present invention relates to a novel squaramide derivative and a use thereof and provides a novel derivative through the strategy of replacing a compound having a urea core with the bioisolate squaramide, whereby the derivative exhib...  
WO/2022/243099A1
A process for preparing substituted biphenyls of the formula (I) which comprises reacting a compound of the formula (Il) in the presence of a base and of a palladium catalyst, with an organoboron compound of the formula (IV).  
WO/2022/238707A1
The present invention relates to a group of resorcinol derivatives as a pharmaceutically active compounds and methods of preparation thereof. Resorcinol derivatives have been used to treat various diseases and disorders. While such treat...  
WO/2022/233243A1
The present application provides an organic compound, and an electronic element and electronic apparatus comprising same, which belong to the technical field of organic electroluminescence. The structure of the organic compound is as sho...  
WO/2022/232109A1
The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.  
WO/2022/230656A1
Provided is a method for producing a methyl-added compound, the method comprising a step for methylating a dinitrile compound represented by formula (1) in the presence of potassium carbonate and dimethyl carbonate to obtain the methyl-a...  
WO/2022/230916A1
The purpose of the present invention is to provide a methyl-methacrylate-containing composition having high quality stability in storage. The aforementioned problem is solved by a methyl-methacrylate-containing composition containing met...  
WO/2022/223678A2
Use of a compound of Formula 1 in a non-aqueous battery electrolyte formulation: wherein: R is an optionally fluorinated alky group, conveniently C1-6; each Y is independently H or F. X is H; a halogen, conveniently F; or an alkyl or a f...  
WO/2022/224278A1
The present invention relates in general, to the field of pharmaceutical compounds, more particularly to the compounds of Formula (I) which acts as inhibitors for PD1/PD-L1 interaction. The present invention further relates to a method o...  
WO/2022/222737A1
The present disclosure belongs to the technical field of organic materials, and provides a nitrogen-containing compound, and an electronic element and an electronic device comprising same. The nitrogen-containing compound has a structure...  
WO/2022/218733A1
The present invention provides a process for producing a substituted enamine compound of formula (I), and a process for producing oxazole compounds from the compound of formula (I). According to the processes of the present invention, it...  
WO/2022/219870A1
Provided is a platinum group metal supported catalyst column through which a reaction of forming a carbon-carbon bond in an aromatic bromide can be carried out at high yield. In the platinum group metal supported catalyst column, a plati...  
WO/2022/219953A1
The purpose of the present invention is to provide: an ion exchanger which shows small shrinkage upon the contact with an organic solvent in a water-wetted state; and a method for producing the ion exchanger. Provided is an ion exchanger...  
WO/2022/218734A1
The present invention provides a substituted enamine compound of formula (I), and a process for producing oxazole compounds from the compound of formula (I). According to the processes of the present invention, it can produce substituted...  
WO/2022/213997A1
Disclosed are a compound comprising a structural unit as represented by at least one of formulae (1)-(4). The compound comprises an alcohol-soluble or water-soluble group. The compound has a large molar extinction coefficient, a color co...  
WO/2022/214068A1
A heat removal pipe group, a fluidized-bed reactor (1) provided with the heat removal pipe group, a method for using the heat removal pipe group to control the temperature of the fluidized-bed reactor (1), and a method for fabricating un...  
WO/2022/214067A1
A cooling coil set, a method for increasing reaction load using the cooling coil set, and an application thereof in preparation of an unsaturated nitrile. The cooling coil set comprises ten cooling coils, and among at least one cooling c...  
WO/2022/214069A1
A heat removal pipe group, a method for controlling the reaction temperature by using the heat removal pipe group, and a method for fabricating unsaturated nitriles. The heat removal pipe group comprises at least one first heat removal p...  
WO/2022/205574A1
The present invention relates to a method for producing entacapone tablets, comprising: auxiliary material sieving, batching, mixing, sieving, mixing, dry granulation, sieving, mixing with magnesium stearate, and pressing into a tablet f...  
WO/2022/206829A1
The present application relates to the field of electroluminescence, and discloses a compound, an organic electroluminescent device and a display apparatus. The structural formulae of the compound are represented by formulae (I) to (III)...  
WO/2022/204519A1
The present disclosure is concerned with substituted N-(5-chloro-4-((4- chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds, and methods of treating and/or preventing neurodegenerative or neurocognitive disorders including, bu...  
WO/2022/192781A1
The present disclosure provides phenalkylamine compounds and their use in treating medical disorders, such as psychiatric diseases and disorders. Pharmaceutical compositions and methods of making various phenalkylamine compounds are prov...  
WO/2022/189190A1
The invention relates to compounds of formula (I), and their use as herbicides. In said formula, R1 to R8 represent groups such as hydrogen, halogen or organic groups such as alkyl, alkenyl, alkynyl, or alkoxy; X is a bond or a divalent ...  
WO/2022/192714A1
Provided herein are methods and compositions for determining whether a patient suffers from systemic amyloidosis, comprising detecting the presence of a misfolded or aggregated protein in a tissue of the patient, wherein the detecting co...  
WO/2022/183798A1
The present application relates to an organic compound, and an organic electroluminescent device and an electronic apparatus using same. The structure of the organic compound is as represented in formula (1). When the organic compound of...  
WO/2022/178691A1
Disclosed is a method for preparing 2-iodo-aryl ether on the basis of o-halogen iodobenzene in the absence of a catalyst, comprising: adding an alkali metal hydride and a phenol into a solvent; and then adding o-halogen iodobenzene for r...  
WO/2022/178692A1
Disclosed in the present invention is a method for preparing 2-iodo aryl ether under the action of alkali metal hydride: adding alkali metal hydride and phenol to a solvent, then adding 1,2-diiodoarene, and reacting at 0-100℃ to obtain...  
WO/2022/180649A1
The present invention relates to a novel process for the preparation of 2,5-dichloro-3-(5-(3,4-dihydroxy-5-nitrophenyl)-1,2,4-oxadia zol-3-yl)-4,6-dimethylpyridine-1-oxide of formula (I). The present invention also relates to the novel i...  
WO/2022/173933A1
Provided herein are processes for the separation of acetonitrile from low-purity feedstock streams. The provided processes are particularly useful for isolating acetonitrile at high purity from chemical manufacturing waste streams that i...  
WO/2022/168754A1
A compound having an anion represented by formula (I) [wherein ring W1 represents an optionally substituted ring; ring W2 represents a ring having at least one double bond as a ring-constituent element and the ring W2 may have a substitu...  
WO/2022/166870A1
Disclosed in the present invention is a preparation method for a tetra-substituted allenoic acid compound based on a palladium catalytic system, that is, an optically active allenoic acid compound having axial chirality is directly const...  
WO/2022/161706A1
The present invention relates to a compound of formula (I) and an organic electronic device comprising a semiconductor layer which comprises a compound of formula (I).  
WO/2022/164291A2
Disclosed herein is a multimeric protein-albumin conjugate. The multimeric protein-albumin conjugate has a multimeric protein variant conjugated with albumin via a linker. In the multimeric protein-albumin conjugate, a predetermined numb...  
WO/2022/165099A2
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to scaffold molecules having anti-hRPN13 activity, proteolysis targeting chimeras (PROTACs) inc...  
WO/2022/160466A1
A 2-cyanoacrylate compound and use thereof for preventing and treating fungal diseases of crops, belonging to the field of fungicides. The 2-cyanoacrylate compound has good fungicidal activity, particularly has good fungicidal activity a...  
WO/2022/151968A1
The present invention relates to a method for purifying key intermediates of Citalopram, i.e. 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-hy droxymethylbenzonitrile and a salt thereof. The method comprises dissolving crude ...  

Matches 101 - 150 out of 16,091