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JP6473774B2 |
To provide a composition more excellent in light absorption characteristics and a method for using the same.A composition has crystalline particles containing cation and anion, where 10 mol or more and 95 mol% or less of the cation is a ...
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JP2018522846A |
The present invention relates to halogen-substituted phenoxyphenylamidines represented by the general formula (I), methods for preparing them, the use of amidines according to the present invention for controlling undesired microorganism...
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JP6306035B2 |
This invention relates to novel sulfoximine substituted quinazoline derivatives of formula I wherein Ar, R1 and R2 are as defined herein, and their use as MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) kinase inhibitors, pharmaceutic...
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JP6283576B2 |
The objective of the present invention is to provide a polyester resin composition which is free from the generation of an irritating gas in the production processes, and which is not increased in the viscosity of a polyester resin even ...
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JP6204102B2 |
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JP6202090B2 |
An amidine compound represented by formula (1) wherein R1, R2, R3, R4 and R5 are the same or different and represent a C1 to C5 alkyl group optionally having one or more halogen atoms or the like; R6 and R7 are a hydrogen atom or the lik...
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JP6198741B2 |
The invention relates to oseltamivir derivatives as influenza neuraminidase inhibitors for treating influenza infections and to a method for producing said compounds.
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JP6178496B2 |
The present invention relates to a new metal complex of the formula (1) wherein: M is a group 4-6 metal R 1 means is a substituent comprising a heteroatom of group 15, through which R 1 is bonded to the imine carbon atom; R 2 -R 5 are th...
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JP6175145B2 |
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JP2017081931A |
To provide antibacterial agents which can prevent infections cause by gram-negative bacteria, other compounds for use in the preparation of medicines and combinations of such compounds.The present invention provides a compound represente...
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JP2017081957A |
To provide compounds useful for reducing the production of visual cycle products.The present invention provides a compound having a structure represented by formula (1) (X is C(Ri)(Rj), or O; T is CH2, CH2CH2 or a direct bond; R1 and R2 ...
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JP2016222655A |
To provide a novel amidine compound having excellent bactericidal activity and a bactericidal agent or a plant disease control agent containing the same as an active ingredient.There is provided a compound represented by the formula [I] ...
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JP6009419B2 |
The application discloses CVD of thin films employing amidinate complexes of the metals lithium, sodium, potassium, beryllium, calcium, strontium, barium, scandium, yttrium, lanthanum and the other lanthanide metals, titanium, zirconium,...
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JP2016529238A |
The present invention relates to a compound of formula (I). [Chemical 1]Provided are a method for producing a compound of the present invention and a therapeutic use thereof. The present invention further provides a combination of a phar...
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JP2016164159A |
To provide compounds that are novel modulators, e.g., activators or agonists, of the human calcium sensing receptor (CaSR) and effective in treatment of chronic kidney disease and osteoporosis.The invention provides a compound represente...
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JP2016160221A |
To provide a reduction method using water as a proton source by means of N-heterocyclic carbene, in which the N-heterocyclic carbene is used actively as a reaction accelerator to realize a hydrogenation reaction by using water as the pro...
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JP5955221B2 |
An object of the present invention is to provide a novel fungicide having an excellent fungicidal activity. The compound used as the fungicide of the present invention is an ethynylphenylamidine compound or a salt thereof, the compound b...
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JP2016104739A |
To provide an ionic compound useful as an ionic conducting material, an electron conducting material, a coloring agent and a catalyst for various chemical reactions and its use.There is provided an ion compound represented by the formula...
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JP5916744B2 |
A present invention provide a technique for easily forming a high-quality cobalt base film, which have a small specific resistance. The present invention comprises a transportation process of a Co[i-C3H7NC(C2H5)N-i-C3H7]2, and a film for...
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JP5900292B2 |
To provide an imino chloride derivative production method and a phenylimidazole derivative production method which are highly safe and can achieve a high yield.A compound represented by the general formula (1) and a chlorinating agent ar...
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JP2016026165A |
To provide novel amide, cyanoamidine, thioamide, amidine, hydroxyimideamide, alkoxyimideamide, aryloxyimideamide and related compounds, which are inhibitors of the 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme.The present ...
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JP2016504320A |
4-Amino-3-chloro-6- (substituted) picolinate from difluoroacetic acid or trifluoroacetic acid, tritylamine or t-butylamine as protecting groups, 3,3-dialkoxyprop-1-in and substituted methyleneamine. Prepared by a series of steps. Methods...
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JP5848698B2 |
The present invention relates to inhibitors of 11- ß-hydroxysteroid dehydrogenase type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, centr...
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JP2015532308A |
The present invention has the general formula (I). [Chemical 1] It relates to a method for preparing a 4-aminobenzoamidine (4-AMBA) salt of (I), preferably a salt with hydrochloric acid or hydrobromic acid, particularly preferably a dich...
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JP5782331B2 |
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JP5757480B2 |
To provide an ionic liquid having low viscosity and excellent in high temperature stability.There is provided an ionic liquid composed of a formamidinium-based cation represented by the general formula and an anion X other than Cl. In th...
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JP5722560B2 |
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JP2015091840A |
To provide a method of synthesizing the factor Xa inhibitor, betrixaban.Described herein is a method of preparing a compound of Formula II comprising a step of reaction between 2-amino-N-(5-chloro-pyridin-2-yl)-5-methoxy-benzamide and 4-...
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JP2015013811A |
To provide a plant disease controlling agent exhibiting a controlling effect against a wide range of plant pathogenic microbes without depending on the application site.There is provided a plant disease controlling agent which contains a...
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JP5629061B2 |
Battery has an electrolyte comprising a solvent and a salt (I) comprising a hydroxonium, nitrosonium, ammonium, metal, organic or organometallic cation and a 5-membered (hetero)cyclic anion. Battery has an electrolyte comprising a solven...
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JP2014196287A |
To provide alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds, which are useful for treating neurodegenerative diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's ...
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JP2014169271A |
To provide an ionic compound in which an anionic filler is non-locally distributed.The provided compound includes either of an amide and a salt thereof, whereas the amide or salt includes a sufficiently large number of anionic segments c...
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JP5567650B2 |
Pharmaceutical compositions comprising 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-
dioxo-1 (2H)-pyrimidinyl]methyl]-benzonitrile and pharmaceutically acceptable salts thereof are provided as well as kits and articles of ...
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JP5555872B2 |
Metal(IV) tetrakis(N,N'-dialkylamidinates) were synthesized and characterized. Exemplary metals include hafnium, zirconium, tantalum, niobium, tungsten, molybdenum, tin and uranium. These compounds are volatile, highly stable thermally, ...
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JP5550993B2 |
Novel monoamidine, monoamidoxime and bisamidine curatives, co-curatives and cure accelerators are provided for use with perfluoroelastomeric compositions as well as novel synthesis methods for making monoamidine- and monoamidoxime-based ...
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JP2014129553A |
To provide improved curatives capable of more easily dispersing in and more quickly curing perfluoroelastomers, particularly cyano curable perfluoroelastomers.Novel monoamidine, monoamidoxime and bisamidine curatives, co-curatives and cu...
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JP5539927B2 |
This invention concerns HIV replication inhibitors of formulathe N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, wherein the ring containing -a1=a2-a3=a4- a...
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JP5479488B2 |
The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds ...
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JP5437594B2 |
Heteroleptic organometallic compounds containing at least one formamidinate ligand are provided. These heteroleptic organometallic compounds have improved properties over conventional vapor deposition precursors. Such compounds are suita...
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JP2013541533A |
A continuous process for generation of phosgene from CO and Cl2 and consumption of the phosgene thus generated in a liquid-phase reaction so as to form organic products P. The process is implemented in two successive reactors R1 and R2, ...
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JP2013209375A |
To provide metal(IV) tetrakis(N,N'-dialkylamidinates) useful for vapor deposition and the like.Metal(IV) tetrakis(N,N'-dialkylamidinates) were synthesized and characterized. Exemplary metals include hafnium, zirconium, tantalum, niobium,...
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JP2013173740A |
To provide ionic compounds in which an anionic charge is delocalized and which is useful for ionic conducting materials, electronic conducting materials, colorants, and the catalyst for various chemical reactions.This invention relates t...
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JP5261181B2 |
The present invention relates to 2,5-di-substituted-4-phenyloxy-substituted-phenyl-amidine derivatives of formula (I) in which the substituents are as in the description, their process of preparation, their use as fungicide or insecticid...
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JP5251627B2 |
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JP5249226B2 |
The invention relates to the compounds of formula (I) having antithrombotic activity which especially inhibit blood clotting factor IXa, to methods for producing the same and to the use thereof as drugs.
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JP5249225B2 |
The invention relates to the compounds of formula I having antithrombotic activity which especially inhibits blood clotting factor IXa, to methods for producing the same and to the use thereof as drugs.
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JP5247661B2 |
This invention concerns HIV replication inhibitors of formulathe N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, wherein the ring containing -a1=a2-a3=a4- a...
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JP5239148B2 |
To provide a 3-iminopropene compound represented by formula (I) where X, Y, and Z are specific substituents, or its salt, a pesticide composition containing the same, a noxious organism controlling agent containing the same, and a method...
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JP2013121919A |
To provide a pharmaceutical product, particularly a pharmaceutical composition having a plasma kallikrein inhibition activity, useful as a prophylactic or therapeutic agent for edemas (particularly hereditary vascular edema), and useful ...
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JP5209649B2 |
Battery has an electrolyte comprising a solvent and a salt (I) comprising a hydroxonium, nitrosonium, ammonium, metal, organic or organometallic cation and a 5-membered (hetero)cyclic anion. Battery has an electrolyte comprising a solven...
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