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Matches 551 - 600 out of 3,496

Document Document Title
WO/2002/008248A1
A method for producing a compound represented by the general formula (VI): (VI) wherein R¿1? represents a hydrogen atom or a linear or branched aliphatic alkyl group having 1 to 4 carbon atoms, R¿2? represents a hydrogen atom or methyl...  
WO/2002/006189A2
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salt and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associa...  
WO/2002/006304A1
A process is described for the preparation of dipeptide derivatves having formula (I) characterized by reaction scheme (II).  
WO/2002/004403A1
The invention relates to substituted piperazine derivatives of general formula (I), wherein R?1¿ to R?7¿ have the meanings given in claim no. 1, isomers thereof and salts thereof, especially physiologically compatible salts thereof, wh...  
WO2001051457A3
The invention relates to a method for producing compounds of formula (I) wherein the radicals R<1> and R<2> have the meanings given in the description and in the claims, which can be used on a large scale.  
WO/2001/098235A2
The invention relates to 3,4-dihydroxybenzyl-substituted carbonic acid derivatives, to their production, and to their use as antioxidants or free-radical scavengers, especially in cosmetic and pharmaceutical preparations and in foodstuff...  
WO/2001/096285A1
The present invention relates to compound of formula (I) wherein R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ and n are as defined in the description and claims and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof...  
WO/2001/096282A1
The invention relates to a method for producing amides or esters from carboxylic acids and from an amine constituent or alcohol constituent in the presence of a 1,3,5-triazine and optionally in the presence of an organic solvent and of a...  
WO/2001/094438A1
The invention relates to urethane compounds which release organoleptically active aromatic alcohols; a method for producing said urethane compounds; and the use thereof in cosmetic, glue, paint and plastic compositions, and cleaning prod...  
WO/2001/092210A1
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the invention are useful as modulators of th...  
WO/2001/091897A1
This invention relates to a process for the continuous preparation of moderate to high viscosity reaction products requiring moderate to long reaction times (e.g. a polymer(s) including prepolymer(s)), specifically relates to the continu...  
WO/2001/090051A1
The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula (I) wherein X and R?1¿ to R?5¿ are as defined in the description and in the claims, as well as hydrates or solvates and/or physiologica...  
WO2000041476A3
Compounds of formula (I) wherein R1 is C1-C4-alkyl or cyclopropyl; R2 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkinyl; or C1-C6-alkyl substituted by 1 to 5 fluorine atoms; R3 is C1-C6-alkyl, C1-C6-alkoxy, C3-C6-cycloalkyl, C3-C6-cycloalkoxy...  
WO/2001/087837A1
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino] -propan-2-ol, carvedilol, or an acid addition salt thereof, is prepared by alkylating 5-chloromethyl-3-[2-(2-methoxy-phenoxy)-ethyl]-oxazolidin-2- one (VII) with 4-hydroxy-carb...  
WO/2001/085675A2
A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having formula (I) wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m is 1, 2 or 3, R...  
WO/2001/080998A1
A reaction vessel (40) represented on Fig.2, and method of identifying a ligand having affinity for a target molecule are disclosed. The reaction vessel (40) includes a first member defining a first chamber (42), the first chamber includ...  
WO/2001/074795A1
A process for preparing amic acid esters of the general formula (7) wherein A, R¿1?, R¿3?, and Het are each as defined in the claim, which comprises reacting an amino acid of the general formula (1) with a halocarbonate ester in the pr...  
WO2000050376A9
Efficient synthetic methods towards mixed aliphatic carbonates through the three component couplings of aliphatic alcohols, alkyl halides and carbon dioxide in the presence of cesium carbonate and tetrabutylammonium iode (TBAI). Due to t...  
WO/2001/070219A1
The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide via a dicarboxylated salicylamide intermediate. The present invention also relates to dicarboxylic salicylamide ...  
WO/2001/068591A1
This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula (I) wherein R?1¿, R?2¿, and R?3¿ are each independently in each occurrence aryl or heteroaryl, R?4¿ is -COOH or tetr...  
WO/2001/068590A1
Process for the preparation of aromatic urethanes consisting in reacting organic carbonates with aromatic amines in reactors operating in continuous, feeding a total quantity of aromatic amines in a percentage, with respect to the weight...  
WO/2001/062706A1
The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases usin...  
WO/2001/060786A1
A compound of the formula [Ig]; wherein R?1¿ is hydrogen or an amino protective group, R¿2? is hydrogen or hydroxy, and R¿3? and R¿4? are independently N-methyl-methoxycarbonylamino, N-ethyl-methoxycarbonylamino, N-propyl-methoxycarb...  
WO2000055124A3
The present invention relates to novel cysteine protease inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.  
WO/2001/056978A1
The invention relates to positional isomer diethyloctandioldicarbamates and diethyloctandioldiallophanates, to a method for the production thereof and to the use thereof as synthetic building blocks and constituents of adhesives, luting ...  
WO/2001/055081A2
Esters derived from fatty acids and juvenoid alcohols of the general formula (I), in which X means the oxygen atom or the NH group, Y means the NH group or the oxygen atom, R means methyl, ethyl, 1-propyl, 2-methylethyl or propargyl and ...  
WO/2001/055097A1
This invention relates to an improved synthesis of 5-(N-[(S)-N-{N,N-bis(2-chloroethyl)amino}phenoxycarbonyl)-$g (g)-glutamyl]amino)isophthalic acid (also named ZD9063P), a prodrug used in Antibody Directed Enzyme Prodrug Therapy (ADEPT),...  
WO/2001/051457A2
The invention relates to a method for producing compounds of formula (I) wherein the radicals R?1¿ and R?2¿ have the meanings given in the description and in the claims, which can be used on a large scale.  
WO/2001/047871A2
Process for the synthesis of polyurethane derivatives from aromatic polyamine compounds. The method involves reaction of an aromatic polyamine compound with CO and O¿2? in the presence of a catalyst comprising a Group VIII or lanthanide...  
WO/2001/047870A2
A process for the preparation of an aromatic polycarbamate which comprises reacting an aromatic polyamine, urea and an alcohol, characterised in that the alcohol is an alkoxylated monoalcohol.  
WO2000050376A3
Efficient synthetic methods towards mixed aliphatic carbonates through the three component couplings of aliphatic alcohols, alkyl halides and carbon dioxide in the presence of cesium carbonate and tetrabutylammonium iode (TBAI). Due to t...  
WO/2001/046120A1
The present invention provides a new process for the preparation of 2S,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitro benzenesulfonylamide hydrochloride, wherein this compound is prepared directly from the chloromethylalcohol....  
WO/2001/044165A1
Processes for industrially producing (aminomethyl)trifluoromethylcarbinol derivatives (I), in particular, optically active compounds, which are useful as materials for producing drugs such as proteases. A process for producing the compou...  
WO/2001/040163A1
Disclosed is a method for preparing a t-butoxycarbonylated amine compound and, more particularly, a method for preparing a t-butoxycarbonylated amine compound where an amine compound is reacted with a t-butylchloroformate in an aqueous o...  
WO/2001/036375A1
This invention relates to new aminoalcohol derivatives or salts thereof represented by formula (I): wherein each symbol is as defined in the specification or salts thereof which have gut selective sympathomimetic, anti-ulcerous, anti-pan...  
WO2001001569A3
The invention relates to a process for preparing (-)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by formula (I) wherein R1 and R2 are as described within the specification.  
WO2000055125A3
The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.  
WO/2001/027074A1
The invention relates to novel processes for preparing differentially protected lysine derivatives via a novel p-anisaldehyde Schiff base intermediate and the intermediate prepared therein.  
WO2000050378A3
The present invention relates to a method of preparing a 1-nitro-3-substituted-3-amino-2-propanol diastereomer represented by Structural Formula (I): In Structural Formula (I), R is an amine protecting group, and R<1> is an amino acid si...  
WO/2001/017952A1
3,4-Disubstituted-1-cyclopentene compounds, in substantially enantiopure form, have the relative stereochemistry according to formula (1A) or (1B) including the opposite enantiomers thereof, wherein R?1¿ is either COOX, wherein X is alk...  
WO2000055126A3
The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.  
WO/2001/010799A1
A method for preparing an N-[(aliphatic or aromatic)carbonyl)]-2-aminoacetamide compound, and for preparing a cyclized compound therefrom, as well as novel resin bound intermediate compounds that are useful for preparing such compounds.  
WO/2001/005747A1
A nitrile compound is prepared by treating a solid supported amide to dehydrate it and cleave it from the support in one operation. The preparation involves acetylation of the amide compound in the presence of a base at a temperature of ...  
WO/2001/000570A1
Problem: To provide intermediates for the synthesis of benzimidazole compounds having an excellent antihyperglycemic activity or salts thereof and a process for the preparation thereof. Means for solutions: A process for the preparation ...  
WO/2001/000634A1
A method for making a vinyl carbonate represented by the formula (I): CH¿2?=CHOC(O)X¿1?R¿1?, wherein X¿1? is oxygen or sulfur and R¿1? is a substituted or an unsubstituted aliphatic alkyl, aryl, aryl alkyl, olefinic, vinyl, or cyclo...  
WO/2001/000558A1
The invention relates to methods for preparing substituted cyclopentene compounds, their intermediates and use as neuraminidase inhibitors.  
WO/2001/001569A2
The invention relates to a process for preparing (-)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by formula (I) wherein R¿1? and R¿2? are as described within the specification.  
WO2000043343A3
A method for the cross-metathesis of terminal olefins is disclosed. The method describes making disubstituted internal olefin products by contacting a first terminal olefin with another first terminal olefin to form a dimer and then cont...  
WO/2000/069944A1
Polymerizable urethane acid compounds are provided. Preferred compounds additionally comprise a hydroxy functionality. These compounds are made by reaction of hydroxy functional acid compounds with isocyanates.  
WO2000051968A8
The present invention is directed to a method for the preparation of a chiral beta -amino ester of formula (I) or (II), wherein R is lower alkyl; and X and Y are the same or different halogens selected from the group consisting of CI, Br...  

Matches 551 - 600 out of 3,496