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Matches 401 - 450 out of 3,510

Document Document Title
WO/2005/063698A1
A process for the preparation of carbamates from organic urea and organic carbonate in presence of a solid base catalyst is disclosed. The process works at the milder reaction conditions and utilizes inexpensive catalysts that can be rec...  
WO/2005/062811A2
One aspect of the present invention relates to a method of preparing allylic carboxylate compounds comprising the step of contacting a compound comprising an allylic hydrogen atom with a carboxylic acid in the presence of palladium, a su...  
WO/2005/061446A2
The present invention relates to a process for preparing an aminoalkyl phenylcarbamate (4), comprising the steps of converting a hydroxy phenyl ketone (2) to a phenylcarbamate ketone (3), and converting the phenylcarbamate ketone (3) to ...  
WO/2005/061445A1
Methods and reagents for rhodium-promoted carbonylation via isocyanate using carbon-isotope labeled carbon monoxide are provided. The resultant carbon­ isotope labeled compounds are useful as radiopharmaceuticals, especially for use in ...  
WO/2005/061434A1
The invention relates to a novel method for producing dendritic trimesic acid triamides.  
WO/2005/058804A1
There is provided a process for the preparation of a compound of Formula: (1) wherein Ar represents an optionally substituted hydrocarbyl or an optionally substituted heterocyclyl group comprising an aromatic moiety; and R1, R2 and R3 ea...  
WO/2005/058805A1
A process for producing an optically active amine compound (IV), characterized in that nucleophilic addition of nucleophilic agent (III) to imine compound (II) is carried out in the presence of asymmetric urea compound (I). An advantageo...  
WO2005010011A3
Disclosed herein are methods for synthesizing 1-(acyloxy)-alkyl prodrug derivatives of drugs through oxidation of 1-acyl-alkyl derivatives of drugs under anhydrous reaction conditions. The methods typically proceed stereospecifically, in...  
WO/2005/054186A2
The present invention relates to methods of preparing a stereoisomerically enriched compound of formula (I), wherein R6 is hydrogen, comprising treating a compound of formula (I), wherein R6 is chosen from C1-C10 alkyl, C2-C10 alkenyl, C...  
WO/2005/047234A1
The invention relates to a method for producing carbamate group-containing (meth)acrylic esters. The inventive method is characterized by reacting at least one carbamate group-containing hydroxy compound with (meth)acrylic anhydride in t...  
WO2005000803A8
A process for producing an asymmetric compound (IV), characterized by causing a compound (II) to add a nucleophilic reagent (III) through conjugate addition in the presence of an asymmetric urea compound (I). Also provided is a nonmetall...  
WO/2005/040099A1
Processes for efficiently producing a 3-substituted (2R,3R)-2-(protected amino)-3-hydroxypropionic acid derivative from a 3-substituted (2S*,3R*)-2,3-epoxypropionic acid. The processes are the following (1) to (3): (1) a process which co...  
WO2004002939A3
The present invention relates to a compound formula [I]: Y is bond, -0-(CH2)n- (in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R<1> is hydrogen, lower alkyl, etc., R<2> is hydrogen or an amino protective group, R<3> is ...  
WO2005016866A3
The present invention is to provide a method for producing the desired optically active beta-amino acid derivatives of high optical purities in high yields, without requiring a step of deprotection. More particularly, the present inventi...  
WO/2005/033180A1
The present invention relates to novel aspartates, their method of production and the use of these mono and polyaspartates as reactive components for polyisocyanates in two-component polyurethane coating compositions and for preparing po...  
WO2005009928A3
The present disclosure provides methods of synthesizing alkylating agents and methods of use.  
WO/2005/033064A1
A process for preparing O-carbamoyl aminoalcohols represented by Formula(I) wherein: n is an integer from 0 and 5; R1, R2, R3 and R4 are individually selected from the group consisting of hydrogen, alkyl, cycloalkyl, substituted or unsub...  
WO/2005/021515A2
The present invention relates to isoxazoline derivatives of structure (I), which can be used as selective inhibitors of phosphodiesterase (PDE) type IV. In particular, compounds disclosed herein can be useful in the treatment of AIDS, as...  
WO2005000803A3
A process for producing an asymmetric compound (IV), characterized by causing a compound (II) to add a nucleophilic reagent (III) through conjugate addition in the presence of an asymmetric urea compound (I). Also provided is a nonmetall...  
WO/2005/016866A2
The present invention is to provide a method for producing the desired optically active β-amino acid derivatives of high optical purities in high yields, without requiring a step of deprotection. More particularly, the present invention...  
WO/2005/016871A1
A process for the manufacture of iodopropynyl butylcarbamate (IPBC) is disclosed wherein the subject reaction is carried out in an aqueous solution of a suitable surfactant. The iodination reactant is metallic iodide salt which serves as...  
WO/2005/009928A2
The present disclosure provides methods of synthesizing alkylating agents and methods of use.  
WO/2005/010011A2
Disclosed herein are methods for synthesizing 1-(acyloxy)-alkyl prodrug derivatives of drugs through oxidation of 1-acyl-alkyl derivatives of drugs under anhydrous reaction conditions. The methods typically proceed stereospecifically, in...  
WO/2005/000803A2
A process for producing an asymmetric compound (IV), characterized by causing a compound (II) to add a nucleophilic reagent (III) through conjugate addition in the presence of an asymmetric urea compound (I). Also provided is a nonmetall...  
WO/2004/101476A1
The invention relates to a process for amino acid synthesis, i.e., the preparation of side chain unsaturated &agr ,&agr -disubstituted-&agr -amino acid derivatives with formula (1) wherein: * denotes a stereogenic C-atom PG represents an...  
WO2004067498A3  
WO/2004/067498A2
The invention relates to compounds of general formula (I), where n = a whole number from 1 to 7, A is selected from one or several groups X, Y and/or Z, X = C1-2 alkylene, optionally substituted by one or more C1-12 alkyl, C3-7 cycloalky...  
WO2004026814A3
The invention is a process for the preparation of compounds of the Formula (I): where R1, R2, R3, R4 and R5 are defined in the specification, which are intermediates useful for the preparation of tubulin inhibitors useful in the treatmen...  
WO2003101917A3
A process for the preparation of compound of formula (I); wherein R<1> is hydrogen, linear, branched or cyclic lower alkyl, cyclohexyl, allyl, propargyl or benzyl; R<2> is hydrogen, methyl, ethyl or propyl; or R<1> and R<2> together with...  
WO/2004/058681A1
A process for producing a benzylamine derivative represented by the general formula (3): (3) (wherein X1 represents halogeno; R1 represents acyl; and R2 represents acyl), characterized by reacting a benzyl compound represented by the gen...  
WO/2004/052844A1
The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA anal...  
WO/2004/052843A1
The invention relates to a process for producing carbamoyloxy (meth)acrylates which comprises transesterification of hydroxyalkyl carbamates with an (meth)acrylate of formula CH2=CR29-COOR30 wherein R29 is hydrogen or methyl and R30 repr...  
WO2003051841A3
Carbamates and related compounds of formula R1 R2NCO-Y or R1 R2NCS-Y wherein R1 and R2 are hydrogen, alkyl, aryl, heteroaryl or may together form a piperidine, piperazine, morpholine or other heterocyclic ring, are inhibitors of hormone ...  
WO2003051842A3
Carbamates and related compounds of formula R1R2NCO-Y or R1R2NCS-Y wherein R1 and R2 may form a ring, are inhibitors of hormone sensitive lipase and are useful for the treatment of any disorder where it is desirable to modulate the plasm...  
WO/2004/046089A1
Novel methods for synthesizing a functional PNA monomer unit and functional PNA oligomer which are for incorporating functional molecules in any desired positions directly or postsynthetically through linkers having various lengths under...  
WO2004011523A3
Phase change solvents for thermoplastic polymers to provide blended compositions. Above the phase change temperature of the solvent, the phase change solvent solubilizes or intimately mixes with the thermoplastic polymer. Below the phase...  
WO/2004/037772A1
The present invention discloses an improved synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride salt. The synthesis is based on the reductive alkylation of Boc-ethylenediamine with ethyl glyoxylate hydrate and furnis...  
WO2003106399A3
The invention provides processes for preparing N-protected beta-amino aldehyde compounds which are useful as synthetic intermediates for preparing glycopeptide antibiotic derivatives. The processes include cleaving a carbon-carbon double...  
WO/2004/026814A2
The invention is a process for the preparation of compounds of the Formula (I): where R1, R2, R3, R4 and R5 are defined in the specification, which are intermediates useful for the preparation of tubulin inhibitors useful in the treatmen...  
WO2003066549A3
A regio- and stereoselective two-stage synthesis of beta-aminoalcohols employs a key transformation, viz., the creation of a cyclic sulfamidate from a precursor diol, mediated by Burgess-type reagents. The generality and scope of this ap...  
WO2002088085A3
This invention relates to methods for preparing certain cholesteryl ester transfer protein (CETP) inhibitors IA or IB and intermediates related thereto.  
WO/2004/024737A1
The invention relates to a method for binding heteroatom-carbon bonds. According to said method, a lithium compound (II) is first generated by reacting aliphatic or aromatic halogen compounds (I) with lithium metal, said compound is then...  
WO/2004/020384A1
The present invention refers to a process for preparing a compound of general formula (A), wherein R is a radical of naproxen or bromonaproxen and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer...  
WO/2004/020385A1
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independent...  
WO/2004/011523A2
Phase change solvents for thermoplastic polymers to provide blended compositions. Above the phase change temperature of the solvent, the phase change solvent solubilizes or intimately mixes with the thermoplastic polymer. Below the phase...  
WO2002079148A3
The present invention provides a more economical method of producing multifunctional carbonate resins. It overcomes the disadvantage of using relatively expensive starting material, such as polyglycidyl ethers, that have traditionally be...  
WO/2004/002939A2
The present invention relates to a compound formula [I]: Y is bond, -0-(CH2)n- (in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R1 is hydrogen, lower alkyl, etc., R2 is hydrogen or an amino protective group, R3 is hydrog...  
WO/2004/000794A1
Allyl carbamates are disclosed. The allyl carbamates are prepared by reacting an isocyanate with an allylic alcohol or alkoxylated allylic alcohol. Suitable isocyanates are selected from hexamethylene diisocyanate (HDI), HDI biuret, dime...  
WO/2003/106399A2
The invention provides processes for preparing N-protected β-amino aldehyde compounds which are useful as synthetic intermediates for preparing glycopeptide antibiotic derivatives. The processes include cleaving a carbon-carbon double b...  
WO/2003/104184A1
The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.  

Matches 401 - 450 out of 3,510