| Document |
Document Title |
|
WO/2012/059436 |
The invention relates to novel compounds of formula (I), in which R1, R2, R3, R4, R5, Y, Q and G are defined as indicated above, to several methods and intermediate products for the production thereof and use thereof as herbicides and/or...
|
|
WO/2012/058866 |
Provided are a benzamide derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the preparation method and use thereof for preparing a medicine for treating cancer, wherein the group definitions of formula ...
|
|
WO/2012/057093 |
The present invention provides a method for commercially advantageously producing, at low cost, an optically active form of an anti-(3S,4R)-3-alkylcarbamoyl-4-hydroxy pyrrolidine derivative or an enantiomer thereof that is a key intermed...
|
|
WO/2012/050101 |
Provided is a method for producing a urethane compound that makes it possible for a urethanation reaction to advance uniformly and to suppress the generation of byproducts. This method for producing a urethane compound comprises reacting...
|
|
WO/2012/039132 |
Disclosed is a method for producing a compound represented by general formula (2) by causing a compound represented by general formula (1) to react with ammonia.
|
|
WO/2012/025502 |
The invention relates to a new process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, ba...
|
|
WO/2012/025501 |
The invention relates to a new process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a y-amino-5-biphenyl-a-methylalkanoic acid, or acid ester, backb...
|
|
WO/2012/023570 |
Provided is an inexpensive, simple, and efficient method for preparing, from a starting material, a nitro compound constituting a diamine precursor compound which is a starting material for producing a polyamic acid and/or polyimide. Com...
|
|
WO/2012/020724 |
A process for preparing aminoadamantyl carbamate derivatives useful as important intermediates for 11βHSD-1 inhibitors is provided. A process for preparing acid addition salts of compounds represented by general formula (II) or solvates...
|
|
WO/2012/014226 |
The present invention discloses novel process for the preparation of (2R)-2-acetamido-N- benzyl-3-methoxypropanamide of Formula I involving novel intermediates of Formula - XIX and Formula - XX.
|
|
WO/2012/008228 |
Disclosed is a method for oxidizing alcohols, wherein it is possible to efficiently oxidize primary alcohols and secondary alcohols and to achieve high reaction efficiency even when air is used as the bulk oxidant. Specifically disclosed...
|
|
WO/2012/005059 |
A method of producing toluene dicarbamate is provided with: a carbamate production step in which toluenediamine, urea and/or an N-unsubstituted carbamic acid ester, and an alcohol are reacted to produce toluene dicarbamate; and a benzoyl...
|
|
WO/2012/002203 |
Disclosed is a production method for obtaining an optically active β-aminocarbonyl compound by a Mannich reaction of an aldimine in which nitrogen is protected and a malonic acid diester, in the presence of optically active BINOL and 1-...
|
|
WO/2012/002538 |
Disclosed is a process for preparing anhydride crystals of the compound represented by formula (1) in a high yield and at a high purity, the compound represented by formula (1) being an important intermediate for the preparation of compo...
|
|
WO/2012/000608 |
The present invention relates to novel beta-aminoaldehyde derivatives of the formulae (I), (II) and (III), in which the substituents R1 to R5 and A have the meaning given in the description, to a novel process for their preparation, to i...
|
|
WO/2012/000608 |
The present invention relates to novel beta-aminoaldehyde derivatives of the formulae (I), (II) and (III), in which the substituents R1 to R5 and A have the meaning given in the description, to a novel process for their preparation, to i...
|
|
WO/2011/161255 |
The present invention provides an alternative synthesis of N-substituted aminotetralines comprising resolution of N-substituted aminotetralins of formula (II), wherein R1, R2 and R3 are as defined for compound of formula (I).
|
|
WO/2011/158598 |
The disclosed carbamate production method is provided with a urea-producing process, a carbamation process, an ammonia-separating process wherein gas is absorbed in water in the presence of carbonate salt to form water with absorbed gas ...
|
|
WO/2011/125429 |
Disclosed is a method for producing a carbamate compound represented by formula (3), wherein a fluorine-containing carbonate diester compound represented by formula (1) and a non-aromatic diamine compound represented by formula (2) are c...
|
|
WO/2011/117393 |
The present invention refers to the preparation of racemic N-Boc-3-hydroxyadamant-1-yl glycine
|
|
WO/2011/113884 |
The present invention relates to N-carbomethoxy-N-methoxy-(2-chloromethyl)-aniline compounds of the formula I, wherein: n is 0, 1, 2 or 3, each R1 is independently selected from halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4- alkoxy or C1-...
|
|
WO/2011/111677 |
Disclosed is a novel bisphosphate compound that can be used with a wide range of reaction substrates and reactions as a catalyst for asymmetric reactions and can achieve an asymmetric reaction with a high yield and high asymmetric yield....
|
|
WO/2011/095110 |
Intermediate compounds which can be used for preparing Lacosamide as well as preparation methods of Lacosamide are provided. The present preparation methods can avoid using expensive CH3I and AgO and can also avoid using Pd-C catalyst.
|
|
WO/2011/092556 |
Herein described is a novel crystalline form of the hydrochloride of the (4- hydroxycarbamoyl-pheny3)-carbamic acid (6-dimethylamino methyl-2- naphtalenyl) ester. In particular, herein described is a polymorph of the hydrochloride of the...
|
|
WO/2011/078000 |
A method for treating an isocyanate residue, which comprises carrying out a thermal decomposition reaction of a carbamate that is produced by the reaction among an amine, urea and/or an N-unsubstituted carbamic acid ester and an alcohol ...
|
|
WO/2011/073362 |
A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmet...
|
|
WO/2011/070585 |
Processes for preparing Rivastigmine, salts and intermediates thereof are disclosed. More specifically, a process for preparing S-(-)-3-[(l -dimethylamino)ethyl]-phenol is provided.
|
|
WO/2011/071860 |
A method for delivering a nucleic acid to a cell can include exposing sample cells to a composition which includes charged lipids.
|
|
WO/2011/062139 |
Provided is a three-step method for manufacturing optically active 3-tert-butoxycarbonylamino-2-fluoro-1-propanol. The provided method can dramatically reduce the amount of a palladium catalyst used and can complete the reaction in one c...
|
|
WO/2011/061675 |
The present invention provides a process for the preparation of N-[(1S)-3-nitro-2oxo- l-(phenylmethyl)propyl]carbamic acid, 1,1-dimethylethyl ester (Nitroketone) of formula I, comprising the steps of, (a) preparing a solution of N- (tert...
|
|
WO/2011/060302 |
The embodiments described herein provide a reduction of an aldehyde or a ketone, such as a Meerwein-Ponnorf-Verley (MPV) reaction of an aldehyde or ketone. In some embodiments, the reaction occurs in the presence of A1[OC(CH3)3]. In some...
|
|
WO/2011/054818 |
The invention relates to a novel non-crystallizing methacrylate and a method for the production thereof. The invention further relates to a photopolymer formulation comprising the methacrylate of the invention as well as to use of said p...
|
|
WO/2011/054818 |
The invention relates to a novel non-crystallizing methacrylate and a method for the production thereof. The invention further relates to a photopolymer formulation comprising the methacrylate of the invention as well as to use of said p...
|
|
WO/2011/054171 |
Tyrosine derivative histone deacetylases inhibitors and preparation methods and applications thereof are disclosed. A kind of powerful histone deacetylases inhibitors, which can effectively treat the diseases of abnormal expression of th...
|
|
WO/2011/048124 |
The invention relates to a method for producing urethanes by reacting aromatic amines by with a dialkyl carbonate, characterized in that the alkyl radical of the organic dialkyl carbonate comprises 4-18 carbon atoms and is branched in th...
|
|
WO/2011/048727 |
Provided is a ruthenium carbonyl complex represented by general formula (1). (1) RuXY(CO)(L) (In general formula (1), X and Y represent anionic ligands and may be the same as each other or different from each other; and L represents a tr...
|
|
WO/2011/048612 |
A process for preparation of propargylated aminoindans or pharmaceutically acceptable salts thereof, comprises: a) reacting an indanone derivative or a salt thereof with propargyl amine or a salt thereof in the presence of a Lewis acid; ...
|
|
WO/2011/037613 |
The present invention relates to salts of 2-(2-((4-(((4-chlorophenyl)(phenyl)-carbamoyloxy)methyl)cycl
ohexyl)methoxy)acetamido)ethanesulfonic acid (Compound 1) and crystalline forms, solvates and hydrates thereof. The present invention ...
|
|
WO/2011/023757 |
A process for preparing iodopropargyl compounds of the formula (I) in which R is hydrogen, in each case optionally substituted C1-C20-alkyl, C2-C20-alkenyl, C6-C20-aryl or C3-C20-cycloalkyl, and n is an integer from 1 to 6, characterized...
|
|
WO/2011/021258 |
Provided is a process for the preparation of an N-substituted carbamic acid O-aryl ester derived from a ureido-containing compound. The process comprises a step of preparing an N-substituted carbamic acid O-aryl ester from both a ureido ...
|
|
WO/2011/021257 |
Provided is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative, and a hydroxy compound containing one or more hydroxy compounds. The method comprise...
|
|
WO/2011/022457 |
Compounds comprising a lactam moiety, and a urethane or urea functional group are presented. By a preferred synthesis route, they are prepared using at least one polymerizable compound comprising an isocyanate moiety and reacting it with...
|
|
WO/2010/122682 |
High-quality N-alkoxycarbonyl-tert-leucines can be efficiently and stably produced via simple operation by reacting tert-leucine with an N-alkoxycarbonylating agent in an amount of 0.90 to 1.00 time by mole that of tert-leucine in the pr...
|
|
WO/2010/116871 |
Disclosed is a process for producing an urethane compound, which comprises reacting a primary amine, urea and/or an N-unsubstituted carbamic acid ester and an alcohol with one another in the presence of a catalyst comprising a first meta...
|
|
WO/2010/113458 |
Disclosed is a commercially advantageous method for manufacturing a 1,5-benzodiazepine compound. A compound (5) is obtained from a reaction formula and used as an intermediate.
|
|
WO/2010/107993 |
(R)-Λ/-benzyl-2-(benzyloxycarbonylamino)-3 -methoxypropionamide is an intermediate useful for preparing lacosamide. It can be prepared, for example, by combining (R)-Λ/-benzyl-2-(benzyloxycarbonylamino)-3 -hydroxypropionamide with dime...
|
|
WO/2010/107993 |
(R)-Λ/-benzyl-2-(benzyloxycarbonylamino)-3 -methoxypropionamide is an intermediate useful for preparing lacosamide. It can be prepared, for example, by combining (R)-Λ/-benzyl-2-(benzyloxycarbonylamino)-3 -hydroxypropionamide with dime...
|
|
WO/2010/105768 |
The invention is directed to a process for preparing aromatic carbamates which comprises the reaction of an aromatic amine with an organic carbonate in the presence of a catalyst characterized in that Zn4O(OAc)6 is used as catalyst.
|
|
WO/2010/105768 |
The invention is directed to a process for preparing aromatic carbamates which comprises the reaction of an aromatic amine with an organic carbonate in the presence of a catalyst characterized in that Zn4O(OAc)6 is used as catalyst.
|
|
WO/2010/103155 |
The invention relates to the production of carbamates in a single reactor (one-pot) using solid catalysts, involving the reaction between at least one nitro compound, an organic carbonate of formula (OR)(OR)C=O, a gas selected from hyd...
|
