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Patent Searching and Data


Matches 701 - 750 out of 7,730

Document Document Title
WO/2010/090031A1
Disclosed is a method for producing an optically active succinimide derivative which is a key intermediate of (3R)-2'-(4-bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'(1'H)- pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone. The method for pr...  
WO/2010/073974A1
Amides or lactams can be reduced respectively into alcohols or amino alcohols in the presence of an 8(VIII) group transition metal complex, a base and hydrogen gas (H2). By appropriately combining an 8(VIII) group transition metal compl...  
WO/2010/075520A1
Allyl 1 {[(α-isobutanoyloxyethoxy)carbonyl] aminomethyl} -1-cyclohexane acetate can be prepared by combining allyl 1-aminomethyl-1-cyclohexane acetate hydrochloride, a polar organic solvent, chloroethyl chloroformate, and an amine base ...  
WO/2010/072727A1
The present invention relates to new retinoid derivatives of Formula (I), and to pharmaceutical compositions containing them for the treatment of patients affected by pathologies such as arthritic conditions, tumours, metastatic cancer, ...  
WO/2010/072798A1
A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drag substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmet...  
WO/2010/064631A1
Provided are novel compounds which generate bases easily when irradiated with long-wavelength light (active energy rays), a photobase generator containing the compounds, and a photobase generation method. Disclosed are compounds represen...  
WO/2010/063403A2
The invention relates to the compounds suitable for radiolabeling with a chelator free radioisotope and radiolabeled compounds of the general Formula (I). Said compounds are ornithine or lysine derivatives.  
WO/2010/063002A2
Gabapentin enacarbil was prepared and purified from intermediates such as 1- haloalkyl carbamate or carbonate and diacid acetal skeleton. For example, a 1-haloalkyl carbonate or carbamate was prepared by combining a C1 to C 10 alcohol or...  
WO/2010/062490A2
The present invention provides methods of forming carbamates, ureas, and isocyanates. In certain embodiments these methods include the step of reacting an amine with an ester-substituted diaryl carbonate to form an activated carbamate wh...  
WO/2010/057378A1
A method for the preparation of docetaxel of formula 1, comprising: (1) acylating the hydroxyl of compound 2 with compound 3 to obtain compound 4; (2) removing the hydroxyl-protecting group R1 of the obtained compound 4 to obtain compoun...  
WO/2010/057515A1
The invention relates to a process for making levocetirizine, to a process for converting the racemic compound (4) into enantiomers, and to compounds used thereby.  
WO/2010/055162A1
Provided is an enantioselective, palladium-catalyzed method for the preparation of γ-amino-α,β-unsaturated carboxylic acid derivatives having the formulas II, III, IV and VIII.  
WO/2010/050523A1
Disclosed is a liquid crystal aligning agent which can provide, without addition of a crosslinking agent, a liquid crystal alignment film that has excellent mechanical strength and is not easily scratched by rubbing. The liquid crystal ...  
WO/2010/049379A1
The present invention relates to a process for the preparation of the chiral compound of formula (V), wherein R1 is a C1-C6 alkyl group optionally substituted with halogens, an aryl optionally substituted, or a trialkyl silyl group, for ...  
WO/2010/047318A1
Disclosed are novel helicene derivative, axially asymmetric amino acid, amine or aminoalcohol derivative, and azaperylene derivative. The inventors have created compounds each represented by general formula (I), (I'), (II), (II') or (III...  
WO/2010/047775A2
Methods of synthesizing a levodopa ester prodrug, salts thereof, and synthetic intermediates thereof are disclosed.  
WO/2010/041739A1
The issue is to provide a method to obtain optically active vinyl-cyclopropane carboxylic acid derivatives with high yield and high optical purity using starting materials that are safe and easily acquired at a low cost. An additional is...  
WO/2010/041748A1
Disclosed is a prophylactic or therapeutic agent for diabetes, diabetic complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, heart failure, cardiomyopathy, myocardial ischemia, cer...  
WO/2010/038837A1
A highly sensitive photosensitive resin composition which can obtain a solubility contrast regardless of the kinds of polyimide precursors, thereby being capable of forming a pattern having a good shape, while maintaining a sufficient pr...  
WO/2010/039256A1
A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or ...  
WO/2010/038828A1
A novel photobase generator which can sensitively generate a base even by h-ray in place of conventional 2-nitro-4,5-dimethoxybenzyloxycarbonylamine compound photobase generators. Specifically disclosed is an N-(α-aromatic group-substit...  
WO/2010/033043A1
The invention provides dendrimeric compounds of the formula 1 comprising amino acids, wherein n is an integer of 1-4, T is an alkylidene -(CH2)2CONH(CH2)2- group, R2 is an -NH2 group or a moiety of a primary organic amine, and P is an am...  
WO/2010/024762A1
A process for stereoselective synthesis of a β-phenylisoserine comprises reacting a carbonyl imine R-C=N-CO-OR1 with a protected α- oxyaldehyde X1O-CH2CHO in the presence of a chiral amine catalyst and oxidizing aldehyde so obtained.  
WO/2010/023892A1
Disclosed is a method of efficiently producing N-carboxy amino acid anhydride. The N-carboxy amino acid anhydride production method is characterized by including a process in which an amino acid organic salt compound and a carbonic acid ...  
WO/2010/023535A1
Disclosed herein are novel intermediates and process for large scale production of (S)- 3-[(1-dimethylamino) ethyl] phenyl-N-ethyl-N-methyl-carbamate (rivastigmine) or its pharmaceutically acceptable salts employing the novel intermediat...  
WO/2010/024775A1
There is provided a compound of Formula (I) or (II) and salts thereof wherein R1 is an imine or an alkylated imine, said imine or alkylated imine comprising a linear or branched alkyl group of length C1 to C5; R2 are each independently (...  
WO/2010/018676A1
A bactericide for agricultural and horticultural use containing an oxime ether derivative represented by formula (I) or at least one salt thereof. (In formula (I), X represents a halogen atom, a C1-20 alkyl group or the like; R1 and R2 e...  
WO/2010/018714A1
Disclosed is an amide derivative having excellent pest control effect, which is represented by general formula (1). In general formula (1), A represents a carbon atom, a nitrogen atom or the like; K represents a non-metal atomic group ne...  
WO/2010/018154A1
The present invention relates to a process for the production of (3aR, 4S, 7aR)-4-hydroxy-4-m-tolylethynyl-octahydro-indole-1-carboxyli c acid methyl ester (I), of carbamic acid (2-chloroethyl)(3-oxocyclohexyl)-alkyl ester enantiomers (I...  
WO/2010/015935A2
Disclosed herein are convenient, industrially advantageous and environmentally friendly processes for the preparation of cinacalcet hydrochloride. Disclosed also herein are novel hydrochloride, oxalate and di-p-toluoyl-L-(+)-tartrate sal...  
WO/2010/013567A1
Disclosed is a pest control agent having an excellent effect, which contains, as an active ingredient, a compound represented by general formula (1). (In the formula, A represents a carbon atom, a nitrogen atom or the like; K represents...  
WO/2010/013666A1
Disclosed is a commercially novel method for producing a carbamate compound by using a carbonic acid ester and an amide compound in the presence of a basic compound, wherein the reaction speed is higher than those in the conventional met...  
WO/2010/010113A1
The present invention is directed to a process for the manufacture of compounds of formula IV wherein R1 is an amino protecting group, and R2 is hydrogen or C1-10 alkyl, comprising a) reacting a compound of formula Ia, wherein M+ is a ca...  
WO/2010/010174A1
The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11 β-hydroxysteroid dehydrogenase...  
WO/2010/008312A1
The inventions relates to chemistry and medicine, in particular to antihypertensive agents and to the methods of the production thereof. The aim of said invention is to develop novel 1-alkyl-2-alkylcarbomoyl-glycerin derivatives which co...  
WO/2010/008886A2
Gabapentin prodrugs and intermediates thereof are described.  
WO/2010/008201A2
The present invention provides a UV-curable coating composition comprising an alkylene oxide-based urethane acrylate monomer and an optical fiber using the same, the optical fiber showing improved water resistance and excellent thermal, ...  
WO/2010/007202A1
The invention relates to the enzymatic resolution of derivatives of cis- and trans-cyclopentane-1,2-diamines in order to obtain enantiomerically pure or enriched compounds, a method for preparing the starting materials for this method, t...  
WO/2010/004231A2
The invention relates to novel compounds having the following formula (I) in which: n is an integer from 1 to 12, in particular from 1 to 8, m and m' are, independently of one another, integers from 0 to 8, - q and q' are, independently ...  
WO/2010/006085A1
The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprisi...  
WO/2010/003046A2
The preparation and use of calcium, barium, magnesium and copper salts of gabapentin enacarbil are described.  
WO/2010/000856A1
The present invention relates to a method for producing substituted aminobiphenylene, in particular 2-aminobiphenylene, and a method for producing (het)acrylic acid amides of such aminobiphenyenes, in particular 2-aminobiphenyene.  
WO/2009/154766A1
Disclosed are aspartic protease inhibitors represented by the following Formula: wherein R1 , R2, R3, R4, R5, R6, R7a, R7b and n are as defined herein, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising...  
WO/2009/151005A1
Disclosed is a method for efficiently producing an isocyanate compound at a low reaction temperature at a low reaction pressure without using a highly toxic phosgene and without going through a complicated process. Specifically, an isocy...  
WO/2009/147217A1
The present invention relates to compounds of formula (I) below in which: - R1 and R3 represent, independently of one another, a methoxy group optionally substituted by one or more fluorine atoms, - R2 and R4 represent, independently of ...  
WO/2009/146539A1
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing 4-(aminome...  
WO/2009/144179A1
The present invention relates to the compound L-menthyl-N-(2-hydroxyphenyl)carbamate, which is effective against body perspiration odor bacteria, in particular against armpit perspiration odor bacteria, and simultaneously effective as an...  
WO/2009/141170A2
The invention relates to a compound suited as entity carrier, having the general formula (I), wherein X is an amine-containing residue further defined herein. The invention further relates to the use of such compounds, a nanocarrier syst...  
WO/2009/141079A1
The invention relates to compounds and the synthesis of [F-18] labelled L-glutamic acid and [F- 18] labelled L-glutamate, to their derivatives according to formula (I) and to the uses thereof.  
WO/2009/139061A1
This invention provides a production process which, in producing an isocyanate without using phosgene, is free from various problems as seen in the prior art and can stably produce the isocyanate at a high yield for a long period of time...  

Matches 701 - 750 out of 7,730