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Matches 401 - 450 out of 7,730

Document Document Title
WO/2016/136963A1
Provided is a method for producing, through chemical synthesis, kakeromycin and derivatives thereof which exhibit antifungal activity and cytotoxicity, and are expected to serve as novel antifungal agents or anticancer agents. Said metho...  
WO/2016/123707A1
The present application relates to a novel process for the preparation of difluoromethyl ether-based derivatives from, for example, aliphatic and aromatic hydroxyl precursors, compositions comprising these compounds and their use, in par...  
WO/2016/119757A1
The present invention relates to a method for preparing a 2-[1-cycloalkylethyl] phenol derivative, i.e. a method for preparing a compound as shown in formula (I) and an isomer thereof, and an intermediate, and the method has the advantag...  
WO/2016/120167A1
The invention relates to polyphenylene polymethylene polyisocyanates having an NCO number of at least 29% and containing less than 2 wt% of carbamides, less than 8 wt% of carbodiimides or uretonimines, and less than 1000 ppm of organic c...  
WO/2016/114670A1
The invention pertains to the synthesis of carbamate and urea compounds. In particular the invention is directed to the synthesis of carbamate and urea compounds which may be used in the production of compounds that are used to stabilize...  
WO/2016/105448A1
This disclosure provides compounds and compositions for use as analgesics and for the treatment of various conditions, such as pain, headaches, allodynia, and fibromyalgia. The disclosure also provides compounds that are ligands, and in ...  
WO/2016/096641A1
The invention relates to novel compounds which are particularly suitable for use as writing monomers in holographic media. The invention further relates to a photopolymer and a holographic medium comprising the compounds according to the...  
WO/2016/097365A1
The present invention relates to a chemical blowing agent comprising at least one tertiary alkyl carbamate. The chemical blowing agent can be activated thermally and is suitable for foaming thermoplastic materials and can for example be ...  
WO/2016/095128A1
A surfactant and a method of forming the surfactant having the formula (I) where a is an integer from 1 to 10, b is an integer from 0 to 10, R1 is –CH3 or -H, n is an integer from 0 to 20, and R2 is a moiety selected from the group con...  
WO/2016/091965A1
The invention relates to special naphthyl urethane acrylates which can be used in particular as writing monomers in photopolymer formulations for holographic media. In addition, the invention relates to a photopolymer formulation compris...  
WO/2016/075605A1
The present invention provides a process for the preparation of crystalline anhydrous compound of Formula (X), Further, the present invention relates to the use of compound of Formula (X) preparation of Raltegravir (I) or its pharmaceuti...  
WO/2016/071347A1
The invention relates to novel carbodiimides comprising terminal urea and/or urethane groups of formula (I), in which R can be identical or different and is selected from the group of -NHCONHRI-, -NHCONR'RII- and -NHCOORIII- groups, wher...  
WO/2016/061393A1
Monomethyl and monoethyl fumarate prodrugs, pharmaceutical compositions comprising the monomethyl and monoethyl fumarate prodrugs, and methods of using monomethyl and monoethyl fumarate prodrugs and pharmaceutical compositions for treati...  
WO/2016/055015A1
Disclosed is a method for synthesizing a sitagliptin intermediate, the method comprising: under the existence of transition metal catalyst of chiral phosphine ligand and hydrogen, conducting asymmetrical reduction ammonification reaction...  
WO/2016/051420A1
The invention relates to the compounds of formula II or their pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The invention further relates to pharmaceutical compositions...  
WO/2016/047644A1
Provided is a production method for an optically active α-trifluormethyl-β-amino acid derivative whereby: a compound indicated by general formula (1) and a compound indicated by general formula (2) are reacted in the presence of a copp...  
WO/2016/049282A1
The invention relates to a compound prepared by (i) reacting (a) at least one compound selected from diisocyanate, polyisocyanate, or mixture thereof; (b) at least one isocyanate-reactive compound selected from a fluorinated alcohol; a c...  
WO/2016/026459A1
The present invention relates to an isopropyl phenol derivative and a preparation method thereof, and in particular relates to a method for preparing compounds shown by formulae (I) and (IV), and their intermediates, and to their interme...  
WO/2016/026827A1
The present invention refers to crystalline (S)-N-Boc-3-hydroxyadamant-1-yl glycine (abbreviated Boc-S-HADGLY) and a process for its preparation. More particularly, the present invention relates to a process for the preparation of crysta...  
WO/2016/019630A1
Disclosed is a method for synthesizing 1,3-disubstituted allene with high optical activity, namely a method for preparing 1,3-disubstituted allene with high optical activity in one step of functionalizing terminal alkyne, aldehyde and ch...  
WO/2016/015596A1
A process of preparing 2, 3-disubstituted-5-oxopyran compounds, comprising cyclizing a compound in the presence of a base and an organic solvent is provided.  
WO/2016/002918A1
Provided is a novel method for producing an indole compound or salt thereof having an ITK-inhibiting effect and being useful in the treatment or prevention of inflammatory diseases and the like. A method for producing N-[2-(6,6-dimethyl-...  
WO/2015/190118A1
The present invention relates to an onium salt, an acrylic acid copolymer containing the onium salt, and an antistatic agent containing the onium salt or the acrylic acid copolymer. The present invention provides an onium salt capable ...  
WO/2015/165352A1
The present invention provides a compound with a structure represented by general formula I or a pharmaceutically acceptable salt thereof, a preparation method for the compound or the salt, and a use of the compound or the pharmaceutical...  
WO/2015/158799A1
The invention relates to a process for preparing alkylaryl carbamates from alkyl formates and at least one amino aryl compound in the presence of a metal-based catalyst. The alkylaryl carbamates can be used for the preparation of isocyan...  
WO/2015/151885A1
Provided is a fluorine-containing monomer, which can be solubilized in a hydrocarbon solvent and also has excellent water and oil repellence, and a manufacturing method therefor. A carboxylic ester / carbamate compound, which is represen...  
WO/2015/152221A1
[Problem] To provide a polymerizable monomer for dental material with which a hardened material having both the properties of high toughness and rigidity can be achieved, and also provide a polymerizable monomer composition for dental ma...  
WO/2015/146905A1
[Problem] To provide: an acrylic or methacrylic compound having an N-alkoxyalkyl group; and a method for producing the acrylic or methacrylic compound. [Solution] An acrylic or methacrylic compound which is represented by formula (1) and...  
WO/2015/132801A1
The present invention discloses a process for the synthesis of dimethyl carbonate (DMC) and further methyl-N-methyl carbamate (MNMC) starting from urea or methyl carbamate using salts such as nitrate or triflate salts of rare earth eleme...  
WO/2015/133247A1
Provided is an industrially advantageous carbamic acid ester production method whereby it becomes possible to produce a carbamic acid ester, such as an aromatic carbamic acid ester, with high yield and high selectivity without requiring ...  
WO/2015/130121A1
The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound.  
WO/2015/127556A1
Compositions for eliciting acute defecation in subjects having a spinal cord injury (SCI subject) are described herein. The compositions may generally comprise one or more of a 5-HT (5-hydroxytryptamine, serotonin) receptor agonist, a be...  
WO/2015/127559A1
The present disclosure relates to compounds of formula I : compositions containing same and methods for treating or preventing a condition associated with brown adipose tissue dysfunction in a subject and/or for converting white adipose ...  
WO/2015/127558A1
Compositions for eliciting acute micturition (voiding activity) in subjects having a spinal cord injury (SCI subject) are described herein. The compositions may generally comprise one or more of a 5-HT (5-hydroxytryptamine, serotonin) re...  
WO/2015/122494A1
Provided is a novel compound having an excellent suppression action against arrhythmia including atrial fibrillation and being useful as a pharmaceutical product having a separated antiviral effect. A compound indicated by general formul...  
WO/2015/123416A1
A method of producing a polycarbodiimide polymer comprises heating a precursor compound at a desired temperature. The method further comprises combining the precursor compound, a diisocyanate compound, and a carbodiimidization catalyst t...  
WO/2015/117146A1
β-Substituted -amino acids, β-substituted γ-amino acid derivatives, and β-substituted γ-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The β-substituted γ-amino acid derivatives and Î...  
WO/2015/115650A1
Provided is a method for producing an optically active carboxylic acid ester at a high yield and with high enantioselectivity using dynamic kinetic resolution, said optically active carboxylic acid ester having an α-nitrogen substituent...  
WO/2015/116786A1
In one aspect, the invention relates to compounds having the formula (I): where R1-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another asp...  
WO/2015/117147A1
β-Substituted β-amino acids, β-substituted β-amino acid derivatives, and β-substituted β-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The β-substituted β-amino acid derivatives and...  
WO/2015/109935A1
The invention generally relates to compounds of formula (I) with neural protective effect, and preparation and uses thereof. The compounds have multiple mechanisms or functions, for example, inhibition of monoamine oxidase and cholineste...  
WO/2015/109666A1
Disclosed are an ester group-containing aromatic propionamide compound, and a preparation method therefor and uses thereof, and provides a chemical structure formula of the new ester group-containing aromatic propionamide compound. The c...  
WO/2015/107064A1
The present invention relates to methods for linking tetrazines with dienophiles to establish at least two linkages by sequentially performing at least two cycloaddition reactions. The methods in particular allow establishing multi-label...  
WO/2015/093469A1
The present invention involves preparing compounds represented by the formula. (In the formula: R1 represents a Br group, an iodine group, a Cl group, an NO2 group, or an NH2 group; R2 represents a halogen group, an NO2 group, an NH2 gro...  
WO/2015/087341A1
The present invention relates to an improved process for the preparation of dimethyl carbonate and methyl-N-methyl carbamate starting from methanol and methyl carbamate catalyzed by ionic liquid catalyst in batch or continuous reactor.  
WO/2015/077451A1
The present invention relates to N-phenyl carbamate derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide 2 receptor.  
WO/2015/076346A1
An optically active 2,6-dimethyltyrosine derivative represented by formula (1) (wherein R1 represents a hydrogen atom or a protecting group for a phenol group; R2 represents a protecting group for an amino group; and * represents an asym...  
WO/2015/075744A1
The present invention relates to novel carbamate intermediate of formula (II), process for its preparation and process for its conversion into 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol, tapentadol and its pharmaceuticall...  
WO/2015/074085A1
What is described is a compound of formula (I), wherein R1 and R2 are the same or different, each a linear or branched alkyl with 1-9 carbons, or an alkenyl or alkynyl with 2 to 11 carbon atoms; L1 and L2 are the same or different, each ...  
WO/2015/060359A1
Provided are a novel diamine, and a polyimide precursor and polyimide using the same. A diamine represented by formula (1). (In formula (1), X1 and X5 each independently represents a single bond or the like, X2 and X4 each independently ...  

Matches 401 - 450 out of 7,730