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Matches 1 - 50 out of 10,085

Document Document Title
WO/2018/118830A1
Disclosed is a process for preparing Compound 8: (8) comprising the step of reacting Compound of 7: (7) wherein R is C1-8 alkyl or benzyl in the presence of a base. Also disclosed are intermediates and processes for preparing the interme...  
WO/2018/114393A1
The present invention relates to novel trifluoromethyloxadiazoles of the formula (I) or an N-oxide and/or their agriculturally useful salts and to their use for controlling phytopathogenic fungi, or to a method for combating phytopathoge...  
WO/2018/117152A1
The purpose of the present invention is to provide: a method for producing a 7H-pyrrolo[2,3-d]pyrimidine derivative which is useful as a Janus kinase (JAK) inhibitory agent; an intermediate of the same; and a method for producing the int...  
WO/2018/101329A1
The purpose of the present invention is to develop a therapeutic agent for inflammatory diseases such as inflammatory bowel disease and NASH, said therapeutic agent having few adverse effects and high efficacy. The present invention prov...  
WO/2018/097580A1
The present invention relates to a photoinitiator and a light-shielding photosensitive resin composition containing the same and, more specifically, to: a photoinitiator comprising compounds of two or more groups selected from a group of...  
WO/2018/096484A1
The current invention offers a process for the production of N-Boc-2-amino-3,3-dimethylbutyric acid by a reaction of tert-Leucine with di-tert-butyl-dicarbonate, the process comprising (i) contacting the tert-Leucine with di-tert-butyl-d...  
WO/2018/090982A1
Provided are a benzodicycloalkane derivative, and a preparation method and use thereof. In particular, provided is a compound of formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method th...  
WO/2018/086993A1
The present invention relates to a process for the synthesis of mono-protected α,ω-diamino alkanes, the use of said proces in a process for the synthesis of a linker drug comprising an α,ω-diamino alkane moiety and the use of the pro...  
WO/2018/087064A1
The invention relates to a method for producing triarylorganoborates from organoboronic acid esters in the presence of an n-valent cation 1/n Kn+, comprising the anhydrous treatment of the reaction mixture, and to the use of the obtained...  
WO/2018/078351A1
Described are compounds for targeting proteases, e.g. serine proteases and their use in the diagnostic methods and methods for treatment of respiratory diseases such as cystic fibrosis. The compounds have the structure [H]-[B]-[A]; where...  
WO/2018/073124A1
The invention relates to the preparation of fluorosubstituted fluoroformate from halosubstituted haloformate by reaction with at least one fluorinating agent in the presence of a catalyst. The further preparation of fluorosubstituted (fl...  
WO/2018/071327A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...  
WO/2018/067971A1
The present invention relates to carbamoyl phenylalaninol compounds and methods of using the same to treat disorders.  
WO/2018/060413A1
The present invention relates to a procatalystcomprising the compound represented by formula Aas an internal electron donor (Formula A), wherein R is hydrogen or a methyl group, N is nitrogen atom; O is oxygen atom; and C is carbon atom....  
WO/2018/060406A1
The present invention relates to a procatalyst comprising the compound represented by formula A as an internal electron donor, Formula A wherein R is hydrogen or a methyl group, N is nitrogen atom; O is oxygen atom; and C is carbon atom....  
WO/2018/050795A1
The present invention relates to a process for preparing a carotenoid mono-ester of the formula (I), including the stereoisomers of formula (I), wherein, R1 is e.g. hydrogen, C1-C20-alkyl, C2-C20-alkenyl, C4-C20-alkdienyl, C6-C20-alktrie...  
WO/2018/043658A1
Provided is an economically efficient method by which a carbamic acid ester is able to be produced with high yield and high selectivity. In a method for producing a carbamic acid ester according to the present invention, an amine, carbon...  
WO/2018/043829A1
Provided are a compound represented by a specific formula, a core-shell dye comprising a core comprising the compound and a shell enclosing the core, a photosensitive resin composition comprising the core-shell dye, and a color filter ma...  
WO/2018/038426A1
The present invention relates to: a novel acid addition salt of an optically active diamine derivative; and a preparation method therefor. The diamine derivative acid addition salt of the present invention can prepare edoxaban with high ...  
WO/2018/032359A1
Provided are an ethyl carbamate hapten combination, artificial antigen combination, and method for preparing same and application of same. The ethyl carbamate artificial antigen combination has the molecular structure as shown in formula...  
WO/2018/033866A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate comp...  
WO/2018/028903A1
Compounds useful for formulating inks, 3D printing resins, molding resins, coatings, sealants and adhesives which exhibit reduced shrinkage stress and high hardness and stiffness when cured are described which include a single free radic...  
WO/2018/024828A1
A process for the preparation of N-(dialkylaminoalkyl)-carbamic acid esters, in particular (propyl N-[3-(dimethylamino)propyl] carbamate) comprising an oxidative carbonylation reaction of a compound of general structure (II) wherein each...  
WO/2018/018091A1
The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.  
WO/2018/016634A1
Provided is a compound represented by formula (0). (0) (In formula (0): RY is a hydrogen atom, a C1–30 alkyl group, or a C6–30 aryl group; RZ is a C1–60 N-valent group or a single bond; each RT is independently an optionally-substi...  
WO/2018/011823A1
Disclosed are compounds and methods for the preparation of Edoxaban. In particular, a camphor sulfonate salt of an amine-protected [(1R,2S,5S)-1,2-amino-5-[(dimethylamino)carbonyl] cyclohexane, an intermediate that may be formed in the s...  
WO/2018/007919A1
The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, ...  
WO/2017/217553A1
[Problem] To provide a novel agricultural chemical, and particularly an herbicide. [Solution] An oxime compound represented by formula (1) and an herbicide containing the same. (In formula (1): B represents B-1 or the like; Q represents ...  
WO/2017/214634A1
This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors, R-isomers, and non-hydr...  
WO/2017/214539A1
The application relates to 2-amino-4-(substituted amino)phenyl carbamate derivatives, or pharmaceutically acceptable salts or solvates thereof, as KCNQ2/3 potassium channel modulators, and methods of their uses.  
WO/2017/211145A1
The present invention discloses a micro/nanomaterial, a product thereof with a surface covalently modified with a hydrophilic material, and a manufacturing method. The surface of the micro/nanomaterial comprises a carboxyl group or poten...  
WO/2017/206692A1
An organic amine salt compound having the general formula (I): An-[Bm+]p. In the formula, An- is anions having -n valence serving as CO2 donors, wherein n = 1, 2, or 3; Bm+ is or contains: ammonium ions and/or organic amine B cations; m ...  
WO/2017/206693A1
An organic amine salt compound having the general formula (I): An-[Bm+]p. In the formula, An- is anions having -n valence serving as CO2 donors, wherein n = 1, 2, or 3; Bm+ is or contains: ammonium ions, hydrazine ions and/or organic ami...  
WO/2017/204144A1
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal o...  
WO/2017/195147A1
The present invention relates to process for preparation of ledipasvir of formula (1) and its novel intermediates. The process involves reacting a compound of formula (4) with compound of formula (5) to yield a compound of formula (3), d...  
WO/2017/191332A3
A process of forming compounds of formula (I) comprising the steps of addition of an amino compound H2NR to a compound of formula (II) followed by cyclization, isomerization and hydrolysis.  
WO/2017/183723A1
The present invention addresses the problem of providing a novel compound having a strong opening action with respect to KCNQ 2-5 channels. Provided is a compound represented by the general formula (I) (in the formula, the definitions of...  
WO/2017/179018A1
There are provided Tissue Transglutaminase (TG2) inhibitor compounds, and compositions and methods of use thereof for the prevention or treatment of a cancer. Compounds of Formula I, and pharmaceutically acceptable salts thereof, are pro...  
WO/2017/181118A1
The present invention provides methods for producing cannabinoid prodrugs. Also described are pharmaceutically acceptable compositions of the prodrugs and a system for the large-scale production of the prodrugs.  
WO/2017/175238A1
: The invention discloses a novel process for highly chemoselective reactions of substituted anilines without any detectable reaction at aromatic amino group. The invention also relates to a novel process for preparation of neostigmine m...  
WO/2017/172476A1
Compounds, compositions, and methods for the treatment of Canavan disease are described.  
WO/2017/170934A1
The present invention pertains to an acetylacetone derivative which is useful in trapping metal elements by complex formation, and a simple and highly versatile synthesis method therefor. More specifically, the present invention pertains...  
WO/2017/160923A1
The present invention relates to formulations of Argan oil and Cannabidiol (CBD). The Formulations of the present invention are useful in treating inflammatory disorders including arthritis. More specifically, the compositions provide sy...  
WO/2017/155120A1
The present invention addresses the problem of providing a long life catalyst which can be produced simply and inexpensively, which exhibits high activity, and in which metal leakage is suppressed. Provided is a catalyst according to sev...  
WO/2017/137343A1
A method for the production of carbamate compounds comprises the steps of: A) reacting an organic primary amine with an organic halogen compound in the presence of a quaternary organic ammonium carbonate and/or bicarbonate, thereby obtai...  
WO/2017/133620A1
The present invention relates to a synthesis process of suvorexant, and a preparation method of novel compounds represented by formulas II, III, IV or V, or a salt or intermediate thereof for preparing the suvorexant. The preparation met...  
WO/2017/131236A1
The present invention relates to the nucleic acid complex expressed by formula 1. Formula 1: (In formula 1, X is an oligonucleotide, L1 and L2 each independently represents a sugar ligand, and S1, S2 and S3 each independently represents ...  
WO/2017/130156A1
The invention relates to compounds of Formula (I), (II), (III) or (IV), salts thereof, pharmaceutical compositions thereof, as well as methods of treating, curing or preventing HIV in subjects.  
WO/2017/131221A1
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4a and R4b are as defined in the specification, processes for their preparation, pharmaceutical compositions cont...  
WO/2017/125093A1
Disclosed are a hydroquinone compound, a preparation method therefor, and an application in tumour resistance or immunomodulation. The structural formula of the hydroquinone compound is as shown in formula I, wherein: X is C=O or CH2; Y ...  

Matches 1 - 50 out of 10,085